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The map label for this gene is hflC [H]

Identifier: 222110311

GI number: 222110311

Start: 1146463

End: 1147368

Strand: Direct

Name: hflC [H]

Synonym: Dtpsy_1098

Alternate gene names: 222110311

Gene position: 1146463-1147368 (Clockwise)

Preceding gene: 222110310

Following gene: 222110312

Centisome position: 30.2

GC content: 58.17

Gene sequence:

>906_bases
GTGAACAGAATCGGATTTATCGCATCGACAGTTCTGCTGTTGCTGGCATTGCTCAGCTCGATGGTGTTCGTCGTCGACCA
ACGCCAGTTTGGCGTGGTGTACGCGTTGGGGCAGATCAAGGAAGTCATCACGGAACCAGGCTTGAATTTCAAGCTACCTC
CACCTTTCCAAAACGTTCGCTACATCGACAAGCGTCTGCTCACGCTGGACAGTTCAGACACCGAGTCGATGCTGACAGCC
GAGAAGCAGCGCGTGGTGATCGATTGGTATGTGCGCTGGCGCATTACCGACCCATCCGAGTACATCCGCAATGTGGGACT
GGACGAGAACGCAGGTGCACTGCAGCTCAATCGGGTGGTCCGCAATGCATTTCAGGAAGAAGTCAACCGTCGCACCGTCA
AGGAGCTGCTGTCGCTCAAGCGCGATGCGCTGATGTCCGACGTGAAACGTGAAGTGCTGGAAGCTGTGCGTGGCTCCAAG
CCTTGGGGTGTCGATGTCGTGGACGTGCGCATCACGCGGGTCGACTACGTAGAAGCGATCACGGAGTCCGTCTATCGACG
CATGGAAGCGGAACGCAAGCGCGTTGCGAATGAACTGCGCTCCACGGGCGCGGCGGAGGGGGAGAAGATTCGCGCAGACG
CAGACCGGCAGCGCGAGATCACCATTGCCAATGCCTACCGCGACGCCCAGAAGATCAAGGGCGAGGGTGATGCGGAAGCT
GCGCGTCTGTATGCGGAGGCATTCGGCCGTGATCCTCAATTTGCACAGTTCTACCGGAGCCTCGAAGCTTACAAGGCGAG
CTTCAACCGCAAGGGCGATGTCATGGTGCTGGATCCGGCGAACTCTGAATTTTTCAAGGTATTCAGAGGCGGGACGGGCA
ATGCATCTGCAGGCCCCCGTCGCTGA

Upstream 100 bases:

>100_bases
AGCGACAGTCCCTCCTGCCGCGACCTCTCAATTTCCCGGCGATTCTCGGTTGCGTGATGCCAACCGTTCGCGCGAACGTG
AGTCCCGATAGGAGAGCCGT

Downstream 100 bases:

>100_bases
TGAGCGACTGATGGCGGTGATCGGCCTCCATGAACGGGTTCTGGATCGCGTTGGGTTGGGTGCTGGTCATCGAAGGGCTG
CTGCCCTTCGTGTCACCTGG

Product: hflc protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MNRIGFIASTVLLLLALLSSMVFVVDQRQFGVVYALGQIKEVITEPGLNFKLPPPFQNVRYIDKRLLTLDSSDTESMLTA
EKQRVVIDWYVRWRITDPSEYIRNVGLDENAGALQLNRVVRNAFQEEVNRRTVKELLSLKRDALMSDVKREVLEAVRGSK
PWGVDVVDVRITRVDYVEAITESVYRRMEAERKRVANELRSTGAAEGEKIRADADRQREITIANAYRDAQKIKGEGDAEA
ARLYAEAFGRDPQFAQFYRSLEAYKASFNRKGDVMVLDPANSEFFKVFRGGTGNASAGPRR

Sequences:

>Translated_301_residues
MNRIGFIASTVLLLLALLSSMVFVVDQRQFGVVYALGQIKEVITEPGLNFKLPPPFQNVRYIDKRLLTLDSSDTESMLTA
EKQRVVIDWYVRWRITDPSEYIRNVGLDENAGALQLNRVVRNAFQEEVNRRTVKELLSLKRDALMSDVKREVLEAVRGSK
PWGVDVVDVRITRVDYVEAITESVYRRMEAERKRVANELRSTGAAEGEKIRADADRQREITIANAYRDAQKIKGEGDAEA
ARLYAEAFGRDPQFAQFYRSLEAYKASFNRKGDVMVLDPANSEFFKVFRGGTGNASAGPRR
>Mature_301_residues
MNRIGFIASTVLLLLALLSSMVFVVDQRQFGVVYALGQIKEVITEPGLNFKLPPPFQNVRYIDKRLLTLDSSDTESMLTA
EKQRVVIDWYVRWRITDPSEYIRNVGLDENAGALQLNRVVRNAFQEEVNRRTVKELLSLKRDALMSDVKREVLEAVRGSK
PWGVDVVDVRITRVDYVEAITESVYRRMEAERKRVANELRSTGAAEGEKIRADADRQREITIANAYRDAQKIKGEGDAEA
ARLYAEAFGRDPQFAQFYRSLEAYKASFNRKGDVMVLDPANSEFFKVFRGGTGNASAGPRR

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=314, Percent_Identity=33.7579617834395, Blast_Score=165, Evalue=4e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.-

Molecular weight: Translated: 34191; Mature: 34191

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRIGFIASTVLLLLALLSSMVFVVDQRQFGVVYALGQIKEVITEPGLNFKLPPPFQNVR
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
YIDKRLLTLDSSDTESMLTAEKQRVVIDWYVRWRITDPSEYIRNVGLDENAGALQLNRVV
HHHHHHHHCCCCCHHHHHHHHHCEEEEEEEEEEEECCHHHHHHHCCCCCCCCHHHHHHHH
RNAFQEEVNRRTVKELLSLKRDALMSDVKREVLEAVRGSKPWGVDVVDVRITRVDYVEAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHH
TESVYRRMEAERKRVANELRSTGAAEGEKIRADADRQREITIANAYRDAQKIKGEGDAEA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHCCCCCHHH
ARLYAEAFGRDPQFAQFYRSLEAYKASFNRKGDVMVLDPANSEFFKVFRGGTGNASAGPR
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHCCCCCCCCCCCC
R
C
>Mature Secondary Structure
MNRIGFIASTVLLLLALLSSMVFVVDQRQFGVVYALGQIKEVITEPGLNFKLPPPFQNVR
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
YIDKRLLTLDSSDTESMLTAEKQRVVIDWYVRWRITDPSEYIRNVGLDENAGALQLNRVV
HHHHHHHHCCCCCHHHHHHHHHCEEEEEEEEEEEECCHHHHHHHCCCCCCCCHHHHHHHH
RNAFQEEVNRRTVKELLSLKRDALMSDVKREVLEAVRGSKPWGVDVVDVRITRVDYVEAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHH
TESVYRRMEAERKRVANELRSTGAAEGEKIRADADRQREITIANAYRDAQKIKGEGDAEA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHCCCCCHHH
ARLYAEAFGRDPQFAQFYRSLEAYKASFNRKGDVMVLDPANSEFFKVFRGGTGNASAGPR
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHCCCCCCCCCCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]