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The map label for this gene is surE

Identifier: 222110293

GI number: 222110293

Start: 1128391

End: 1129173

Strand: Direct

Name: surE

Synonym: Dtpsy_1080

Alternate gene names: 222110293

Gene position: 1128391-1129173 (Clockwise)

Preceding gene: 222110285

Following gene: 222110294

Centisome position: 29.72

GC content: 61.56

Gene sequence:

>783_bases
ATGAAAATCCTCATCTCCAACGACGACGGCTACCAGGCGCCTGGCATCGTGGCGCTGCATGACGCCCTTAAGACCATTGC
TGATGTGGAAGTGGTGGCTCCCGAACACAACAATAGCGCGAAGTCGAACGCCCTGACGCTGCATTCGCCGTTGTATGTGC
AAACCGCGCACAACGGCTTTCGCTATGTCAATGGCACGCCCGCCGATTGTGTGCACATTGCGCTGACGGGCCTGCTGGGT
TACCGGCCCGATCTGGTGGTCTCCGGCATCAACAACGGTGCCAACATGGGCGACGACACAATTTATTCCGGCACGGTGGG
TGCTGCGATGGAAGGCTATCTTTTTGGGATCCCGTCCATCGCCTTTTCGCAGGTGGACAAGGGGTGGGGCGAGATCGAGT
CGGCTGCGCGCAAGGCGCGCGAGATCGTTCAGCAGATGGATCGCCAAAACCTGGTCGGCGAAGCCCCCTGGCTGTTGAAT
GTCAACATTCCCAATATGCCGTATGACGCATTGCGGCCCTTGCGCATGTGCCGCCTGGGCCGGCGCCATGCGGCAGAGCG
TGTCATTGAGCAGCAGAGCCCGCGTGGGGAACTGATGTACTGGATCGGTGGCGCTGGCGCCGCCAAGGACGCGGCGGAGG
GCACCGATTTTCATGCCACGGCGCACGGCCATGTATCCGTCACGCCATTGAAGGTGGACCTGACCGATTACGACGGACTG
GGGTATTGGGCGCAGACGGTGGCCCGTCTCGTACCAGCGCAGGCGTCCGGCGAGGTGGCTTGA

Upstream 100 bases:

>100_bases
GCATCATAGGGGCCGCCTCGGAGGCTGGGTTGTCCCTTGCGTGACCAGCGACAGCGTGTGTGCGCGCTCCTACAATGCCA
GCCGTTCTGCCTTCCAGACC

Downstream 100 bases:

>100_bases
TGCAGCGGCGTCCAGGTTTTCCTGCGCGGATCGACTGGCGCCAACCCGGTGCACCCACCGCGGCGCCACCGGTAGGCGCG
CGCCGCGAGGTGCAGCCGCC

Product: stationary phase survival protein sure

Products: NA

Alternate protein names: Nucleoside 5'-monophosphate phosphohydrolase

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MKILISNDDGYQAPGIVALHDALKTIADVEVVAPEHNNSAKSNALTLHSPLYVQTAHNGFRYVNGTPADCVHIALTGLLG
YRPDLVVSGINNGANMGDDTIYSGTVGAAMEGYLFGIPSIAFSQVDKGWGEIESAARKAREIVQQMDRQNLVGEAPWLLN
VNIPNMPYDALRPLRMCRLGRRHAAERVIEQQSPRGELMYWIGGAGAAKDAAEGTDFHATAHGHVSVTPLKVDLTDYDGL
GYWAQTVARLVPAQASGEVA

Sequences:

>Translated_260_residues
MKILISNDDGYQAPGIVALHDALKTIADVEVVAPEHNNSAKSNALTLHSPLYVQTAHNGFRYVNGTPADCVHIALTGLLG
YRPDLVVSGINNGANMGDDTIYSGTVGAAMEGYLFGIPSIAFSQVDKGWGEIESAARKAREIVQQMDRQNLVGEAPWLLN
VNIPNMPYDALRPLRMCRLGRRHAAERVIEQQSPRGELMYWIGGAGAAKDAAEGTDFHATAHGHVSVTPLKVDLTDYDGL
GYWAQTVARLVPAQASGEVA
>Mature_260_residues
MKILISNDDGYQAPGIVALHDALKTIADVEVVAPEHNNSAKSNALTLHSPLYVQTAHNGFRYVNGTPADCVHIALTGLLG
YRPDLVVSGINNGANMGDDTIYSGTVGAAMEGYLFGIPSIAFSQVDKGWGEIESAARKAREIVQQMDRQNLVGEAPWLLN
VNIPNMPYDALRPLRMCRLGRRHAAERVIEQQSPRGELMYWIGGAGAAKDAAEGTDFHATAHGHVSVTPLKVDLTDYDGL
GYWAQTVARLVPAQASGEVA

Specific function: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family

Homologues:

Organism=Escherichia coli, GI1789101, Length=251, Percent_Identity=47.808764940239, Blast_Score=219, Evalue=1e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SURE_ACIET (B9MFW6)

Other databases:

- EMBL:   CP001392
- RefSeq:   YP_002552557.1
- ProteinModelPortal:   B9MFW6
- GeneID:   7382889
- GenomeReviews:   CP001392_GR
- KEGG:   dia:Dtpsy_1080
- ProtClustDB:   PRK00346
- GO:   GO:0005737
- HAMAP:   MF_00060
- InterPro:   IPR002828
- Gene3D:   G3DSA:3.40.1210.10
- TIGRFAMs:   TIGR00087

Pfam domain/function: PF01975 SurE; SSF64167 SurE-like_Pase/nucleotidase

EC number: =3.1.3.5

Molecular weight: Translated: 27931; Mature: 27931

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILISNDDGYQAPGIVALHDALKTIADVEVVAPEHNNSAKSNALTLHSPLYVQTAHNGF
CEEEEECCCCCCCCCCHHHHHHHHHHHCEEEECCCCCCCCCCCEEEEECCEEEEECCCCE
RYVNGTPADCVHIALTGLLGYRPDLVVSGINNGANMGDDTIYSGTVGAAMEGYLFGIPSI
EEECCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCEECCCHHHHHCCCEECCCHH
AFSQVDKGWGEIESAARKAREIVQQMDRQNLVGEAPWLLNVNIPNMPYDALRPLRMCRLG
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHH
RRHAAERVIEQQSPRGELMYWIGGAGAAKDAAEGTDFHATAHGHVSVTPLKVDLTDYDGL
HHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCEEEEECCEEEEEEEEEEECCCCCC
GYWAQTVARLVPAQASGEVA
CHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKILISNDDGYQAPGIVALHDALKTIADVEVVAPEHNNSAKSNALTLHSPLYVQTAHNGF
CEEEEECCCCCCCCCCHHHHHHHHHHHCEEEECCCCCCCCCCCEEEEECCEEEEECCCCE
RYVNGTPADCVHIALTGLLGYRPDLVVSGINNGANMGDDTIYSGTVGAAMEGYLFGIPSI
EEECCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCEECCCHHHHHCCCEECCCHH
AFSQVDKGWGEIESAARKAREIVQQMDRQNLVGEAPWLLNVNIPNMPYDALRPLRMCRLG
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHH
RRHAAERVIEQQSPRGELMYWIGGAGAAKDAAEGTDFHATAHGHVSVTPLKVDLTDYDGL
HHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCEEEEECCEEEEEEEEEEECCCCCC
GYWAQTVARLVPAQASGEVA
CHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA