Click here to switch to the map view.

The map label for this gene is uppP

Identifier: 222110285

GI number: 222110285

Start: 1116773

End: 1117597

Strand: Direct

Name: uppP

Synonym: Dtpsy_1072

Alternate gene names: 222110285

Gene position: 1116773-1117597 (Clockwise)

Preceding gene: 222110280

Following gene: 222110293

Centisome position: 29.42

GC content: 65.33

Gene sequence:

>825_bases
GTGGACACTCTCTTGCTGCTCAAGGCCGCCATCATGGGCGTGGTCGAAGGGCTGACCGAATTCCTCCCCATCTCTTCCAC
CGGCCACCTGATCCTGGCCGGGTCGCTGCTCGGGTTTGACGATGCCAAGGCCAAGGTCTTCGACATCGCCATCCAGACCG
GCGCCATTTTCGCGGTCATTCTGGTCTATTGGCAGCGCATCCGCGCGACGCTGGTGGCGCTGCCCACCGAGCGGCAGGCG
CGTCGTTTCGCCTTAAACGTGCTGATCGGCTTTCTTCCGGCCGTGCTGCTGGGTCTGTTGCTGGGCAAGGCCATCAAGGC
GCATCTGTTCACGCCGGTGGTGGTGGCTAGCACCTTCATCCTGGGCGGCTTCGTCATCCTCTGGGCCGAGCGGCGCCAGC
AGGCCGCCGTGCGCATCCATGCCGTGGACGACATGACGCCGCTGGACGCGCTGAAGGTTGGCCTGGTGCAGTGCCTGGCC
ATGGTGCCCGGCACCAGCCGCAGCGGTGCCACCATCATCGGCGGCATGCTGCTGGGGCTGTCGCGCAAGGCGGCCACCGA
CTATTCGTTCTTTCTCGCCATCCCCACGCTGATCGGCGCAGGCGTCTACAGCCTCTACAAGGAGCGCGCGCTGCTGTCGG
CGGCCGACATTCCGCTGTTTGCCGTGGGACTGGTGTTTTCGTTCATCAGCGCCTGGCTGTGCGTGCGCTGGCTGCTGCGC
TACATCAGCTCGCACAGCTTCGTGCCGTTCGCCTGGTATCGCATCGCGTTTGGCCTGGTGGTGCTGGTCACGGCATGGAG
CGGCCTGGTGACCTGGGCCGAATAG

Upstream 100 bases:

>100_bases
TTCTGGCGTATGGCCCGGCAGGACACAGGGCGTGACACCCGTGTCACGCCGCACGGGGCTGATAATCCGCGCTTTGCTTT
TTCGCTGTCAGGACGCTTGC

Downstream 100 bases:

>100_bases
CCGCGTCAGGACGACGCCAGCGCCAGGTCGCCCTTGTTGCGGCGCACGCAGAACTTGCCCTGCTGCTTGCCGCTGTACAT
GGCGGCGTCCGCCAGGCGGA

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MDTLLLLKAAIMGVVEGLTEFLPISSTGHLILAGSLLGFDDAKAKVFDIAIQTGAIFAVILVYWQRIRATLVALPTERQA
RRFALNVLIGFLPAVLLGLLLGKAIKAHLFTPVVVASTFILGGFVILWAERRQQAAVRIHAVDDMTPLDALKVGLVQCLA
MVPGTSRSGATIIGGMLLGLSRKAATDYSFFLAIPTLIGAGVYSLYKERALLSAADIPLFAVGLVFSFISAWLCVRWLLR
YISSHSFVPFAWYRIAFGLVVLVTAWSGLVTWAE

Sequences:

>Translated_274_residues
MDTLLLLKAAIMGVVEGLTEFLPISSTGHLILAGSLLGFDDAKAKVFDIAIQTGAIFAVILVYWQRIRATLVALPTERQA
RRFALNVLIGFLPAVLLGLLLGKAIKAHLFTPVVVASTFILGGFVILWAERRQQAAVRIHAVDDMTPLDALKVGLVQCLA
MVPGTSRSGATIIGGMLLGLSRKAATDYSFFLAIPTLIGAGVYSLYKERALLSAADIPLFAVGLVFSFISAWLCVRWLLR
YISSHSFVPFAWYRIAFGLVVLVTAWSGLVTWAE
>Mature_274_residues
MDTLLLLKAAIMGVVEGLTEFLPISSTGHLILAGSLLGFDDAKAKVFDIAIQTGAIFAVILVYWQRIRATLVALPTERQA
RRFALNVLIGFLPAVLLGLLLGKAIKAHLFTPVVVASTFILGGFVILWAERRQQAAVRIHAVDDMTPLDALKVGLVQCLA
MVPGTSRSGATIIGGMLLGLSRKAATDYSFFLAIPTLIGAGVYSLYKERALLSAADIPLFAVGLVFSFISAWLCVRWLLR
YISSHSFVPFAWYRIAFGLVVLVTAWSGLVTWAE

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=260, Percent_Identity=45.3846153846154, Blast_Score=223, Evalue=9e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_ACIET (B9MFI6)

Other databases:

- EMBL:   CP001392
- RefSeq:   YP_002552549.1
- GeneID:   7382881
- GenomeReviews:   CP001392_GR
- KEGG:   dia:Dtpsy_1072
- ProtClustDB:   PRK00281
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 29650; Mature: 29650

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x2175bd1c)-; HASH(0x2392c1d0)-; HASH(0x23930f50)-; HASH(0x2393104c)-; HASH(0x23930ff8)-; HASH(0x2392e6f0)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTLLLLKAAIMGVVEGLTEFLPISSTGHLILAGSLLGFDDAKAKVFDIAIQTGAIFAVI
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
LVYWQRIRATLVALPTERQARRFALNVLIGFLPAVLLGLLLGKAIKAHLFTPVVVASTFI
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGGFVILWAERRQQAAVRIHAVDDMTPLDALKVGLVQCLAMVPGTSRSGATIIGGMLLGL
HHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHC
SRKAATDYSFFLAIPTLIGAGVYSLYKERALLSAADIPLFAVGLVFSFISAWLCVRWLLR
CHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
YISSHSFVPFAWYRIAFGLVVLVTAWSGLVTWAE
HHCCCCCCHHHHHHHHHHHHHHHHHHHCHHCCCH
>Mature Secondary Structure
MDTLLLLKAAIMGVVEGLTEFLPISSTGHLILAGSLLGFDDAKAKVFDIAIQTGAIFAVI
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
LVYWQRIRATLVALPTERQARRFALNVLIGFLPAVLLGLLLGKAIKAHLFTPVVVASTFI
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGGFVILWAERRQQAAVRIHAVDDMTPLDALKVGLVQCLAMVPGTSRSGATIIGGMLLGL
HHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHC
SRKAATDYSFFLAIPTLIGAGVYSLYKERALLSAADIPLFAVGLVFSFISAWLCVRWLLR
CHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
YISSHSFVPFAWYRIAFGLVVLVTAWSGLVTWAE
HHCCCCCCHHHHHHHHHHHHHHHHHHHCHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA