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The map label for this gene is ttuD [H]

Identifier: 222110255

GI number: 222110255

Start: 1083205

End: 1084527

Strand: Direct

Name: ttuD [H]

Synonym: Dtpsy_1042

Alternate gene names: 222110255

Gene position: 1083205-1084527 (Clockwise)

Preceding gene: 222110254

Following gene: 222110256

Centisome position: 28.53

GC content: 72.41

Gene sequence:

>1323_bases
ATGACCATGACAGCCCCAGACCCCTTGCGAGACCCTCAAGCCTTCCTGCTGCACCTCTACCGCGTGGCGGTGCAGCGCGC
CCAGCCCTTGCACAGCATGGCGCAGCATCTGCCGCCGCCACCCAAGGGGCGCACCGTGGTGCTGGGCGCGGGCAAGGCGG
GTGCCTCCATGGCGCAGGCGCTGGAGGCGCTGTGGCCGCAGGATGCACCGCTGTCGGGGCTGGTGGTCACGCGCTACGGC
CACATACCGCCGCGGCCCGAGGGGTTGGCGCAGCGCCTGGAAGTCGTCGAGGCCGCGCACCCCGTGCCCGACGCGGCGGG
CCTGGCCGCGGCCGAGCGCATCCTGGCGCTGACCCGAGGGCTGACCGAAGACGACCTGGTGCTGTGTCTCATCTCGGGCG
GTGGCTCGGCGCTGCTCACGCTGCCGGCCGAAGGCATCACGCTGGAGGAGAAGCAACGCATCAACCGCGCACTGCTGGAA
AGCGGCGCGGCCATCGGCGAGATGAACTGCGTGCGCAAGCACCTCTCGCGCATCAAGGGCGGTCGCCTGGCGGCAGCCTG
CGCGCCGGCGCGCGTCGTCACGCTGACCATCAGCGATGTGCCGGGGGACGACCCTTCCGTGATCGCCAGCGGCCCCACGG
TCCCCGACGCCAGCACCTGCGCTGACGCGCTGGACATCCTGGCGCGCTACCGCATCGACATTCCCGCCGCCGTGCACACA
GCGCTGCAGGCCGGTGCACTGGAAACCCCCAAGCTCGGCGATGTCCGCTTTGCCGGCCATGCGGTGCACATGATCGCGAC
GCCCCAGCAGTCGCTGCAGGCAGCGGCGGATGCGGCGCGCGCGGCGGGGGTGGCGGCGTACATCCTGTCCGACGAGATGG
AGGGCGAGTCGCGCGAGGTGGGCAAGGTGCACGCCGCGCTGGCGCGTGCGGTGGCGCGCCACGGCCAGCCGTTTTCGCGG
CCGTGCGTGATTCTTTCGGGCGGCGAGACCACCGTCACCGTGCGCCCGCGCGCCCCGGGCGCGCCGAAGGGGCGCGGCGG
CCGCGCGGGCGAGTTCTGCATGGGCCTGGCGCAGGCGCTGCAGGGGCAGGAAGGGGTGTGGGCGCTGGCGGCCGATACCG
ACGGCATCGACGGCGTGGAAGACAACGCCGGCGCACGCGTGGCACCCGACACGCTGGCGCGCGCGGCGGCGCAGGGCGCA
CGCATCGGCGACCATCTAGACCGCAACGACGCCTACGGCTACTTCGAGCGGCTGGGCGATCTGGTCGTCACGGGGCCCAC
GCACACCAATGTGAACGACTTCCGCGCGCTACTTGTTTTGTAG

Upstream 100 bases:

>100_bases
CTTTGCGCGACTGGTCAAGGAAGCCAAGGTTTCGCTGGATGGACGGTAGGGCTTGTGCCGGCCGCGTGCTTTGGATAATG
CGCGGCGGAGACAACGACCC

Downstream 100 bases:

>100_bases
CTTGCCGCGCCTGCTGTTGCTGGATTTCAGATACGAATGCATCTGAATGCGGCTTCTATCAGGCGCTGGCAGCTCACTTT
TTTGATCTGCTGGCGCGGGC

Product: hydroxypyruvate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MTMTAPDPLRDPQAFLLHLYRVAVQRAQPLHSMAQHLPPPPKGRTVVLGAGKAGASMAQALEALWPQDAPLSGLVVTRYG
HIPPRPEGLAQRLEVVEAAHPVPDAAGLAAAERILALTRGLTEDDLVLCLISGGGSALLTLPAEGITLEEKQRINRALLE
SGAAIGEMNCVRKHLSRIKGGRLAAACAPARVVTLTISDVPGDDPSVIASGPTVPDASTCADALDILARYRIDIPAAVHT
ALQAGALETPKLGDVRFAGHAVHMIATPQQSLQAAADAARAAGVAAYILSDEMEGESREVGKVHAALARAVARHGQPFSR
PCVILSGGETTVTVRPRAPGAPKGRGGRAGEFCMGLAQALQGQEGVWALAADTDGIDGVEDNAGARVAPDTLARAAAQGA
RIGDHLDRNDAYGYFERLGDLVVTGPTHTNVNDFRALLVL

Sequences:

>Translated_440_residues
MTMTAPDPLRDPQAFLLHLYRVAVQRAQPLHSMAQHLPPPPKGRTVVLGAGKAGASMAQALEALWPQDAPLSGLVVTRYG
HIPPRPEGLAQRLEVVEAAHPVPDAAGLAAAERILALTRGLTEDDLVLCLISGGGSALLTLPAEGITLEEKQRINRALLE
SGAAIGEMNCVRKHLSRIKGGRLAAACAPARVVTLTISDVPGDDPSVIASGPTVPDASTCADALDILARYRIDIPAAVHT
ALQAGALETPKLGDVRFAGHAVHMIATPQQSLQAAADAARAAGVAAYILSDEMEGESREVGKVHAALARAVARHGQPFSR
PCVILSGGETTVTVRPRAPGAPKGRGGRAGEFCMGLAQALQGQEGVWALAADTDGIDGVEDNAGARVAPDTLARAAAQGA
RIGDHLDRNDAYGYFERLGDLVVTGPTHTNVNDFRALLVL
>Mature_439_residues
TMTAPDPLRDPQAFLLHLYRVAVQRAQPLHSMAQHLPPPPKGRTVVLGAGKAGASMAQALEALWPQDAPLSGLVVTRYGH
IPPRPEGLAQRLEVVEAAHPVPDAAGLAAAERILALTRGLTEDDLVLCLISGGGSALLTLPAEGITLEEKQRINRALLES
GAAIGEMNCVRKHLSRIKGGRLAAACAPARVVTLTISDVPGDDPSVIASGPTVPDASTCADALDILARYRIDIPAAVHTA
LQAGALETPKLGDVRFAGHAVHMIATPQQSLQAAADAARAAGVAAYILSDEMEGESREVGKVHAALARAVARHGQPFSRP
CVILSGGETTVTVRPRAPGAPKGRGGRAGEFCMGLAQALQGQEGVWALAADTDGIDGVEDNAGARVAPDTLARAAAQGAR
IGDHLDRNDAYGYFERLGDLVVTGPTHTNVNDFRALLVL

Specific function: Degrades an unidentified toxic product from the first step of tartrate degradation [H]

COG id: COG2379

COG function: function code G; Putative glycerate kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI31543063, Length=395, Percent_Identity=36.9620253164557, Blast_Score=174, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI193205461, Length=422, Percent_Identity=29.3838862559242, Blast_Score=151, Evalue=6e-37,
Organism=Drosophila melanogaster, GI19920578, Length=391, Percent_Identity=31.2020460358056, Blast_Score=128, Evalue=7e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007835 [H]

Pfam domain/function: PF05161 MOFRL [H]

EC number: =1.1.1.81 [H]

Molecular weight: Translated: 45719; Mature: 45588

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMTAPDPLRDPQAFLLHLYRVAVQRAQPLHSMAQHLPPPPKGRTVVLGAGKAGASMAQA
CCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHH
LEALWPQDAPLSGLVVTRYGHIPPRPEGLAQRLEVVEAAHPVPDAAGLAAAERILALTRG
HHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCC
LTEDDLVLCLISGGGSALLTLPAEGITLEEKQRINRALLESGAAIGEMNCVRKHLSRIKG
CCCCCEEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
GRLAAACAPARVVTLTISDVPGDDPSVIASGPTVPDASTCADALDILARYRIDIPAAVHT
CCEEEECCCCEEEEEEEECCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCHHHHH
ALQAGALETPKLGDVRFAGHAVHMIATPQQSLQAAADAARAAGVAAYILSDEMEGESREV
HHHHCCCCCCCCCCEEECCCEEEEEECCHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHH
GKVHAALARAVARHGQPFSRPCVILSGGETTVTVRPRAPGAPKGRGGRAGEFCMGLAQAL
HHHHHHHHHHHHHCCCCCCCCEEEEECCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHH
QGQEGVWALAADTDGIDGVEDNAGARVAPDTLARAAAQGARIGDHLDRNDAYGYFERLGD
CCCCCEEEEEECCCCCCCCCCCCCCEECHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCC
LVVTGPTHTNVNDFRALLVL
EEEECCCCCCHHHHHEEEEC
>Mature Secondary Structure 
TMTAPDPLRDPQAFLLHLYRVAVQRAQPLHSMAQHLPPPPKGRTVVLGAGKAGASMAQA
CCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHH
LEALWPQDAPLSGLVVTRYGHIPPRPEGLAQRLEVVEAAHPVPDAAGLAAAERILALTRG
HHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCC
LTEDDLVLCLISGGGSALLTLPAEGITLEEKQRINRALLESGAAIGEMNCVRKHLSRIKG
CCCCCEEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
GRLAAACAPARVVTLTISDVPGDDPSVIASGPTVPDASTCADALDILARYRIDIPAAVHT
CCEEEECCCCEEEEEEEECCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCHHHHH
ALQAGALETPKLGDVRFAGHAVHMIATPQQSLQAAADAARAAGVAAYILSDEMEGESREV
HHHHCCCCCCCCCCEEECCCEEEEEECCHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHH
GKVHAALARAVARHGQPFSRPCVILSGGETTVTVRPRAPGAPKGRGGRAGEFCMGLAQAL
HHHHHHHHHHHHHCCCCCCCCEEEEECCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHH
QGQEGVWALAADTDGIDGVEDNAGARVAPDTLARAAAQGARIGDHLDRNDAYGYFERLGD
CCCCCEEEEEECCCCCCCCCCCCCCEECHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCC
LVVTGPTHTNVNDFRALLVL
EEEECCCCCCHHHHHEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]