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The map label for this gene is nuoC [H]

Identifier: 222110088

GI number: 222110088

Start: 897469

End: 898077

Strand: Direct

Name: nuoC [H]

Synonym: Dtpsy_0874

Alternate gene names: 222110088

Gene position: 897469-898077 (Clockwise)

Preceding gene: 222110087

Following gene: 222110089

Centisome position: 23.64

GC content: 60.92

Gene sequence:

>609_bases
ATGACTGCTATTGCCATTCACCCTGAGAGCCTGCGGGACGTGGTTGCCTCCGCTCTGGGTGACCGCGTGCGCCAGATCTC
GGTGGCGCTGGATGAGGTGACCGTGGTGGTGTCCGCTGCGCGCTATCTCGAAGCCATGCAAATCCTGCGCGATGCGCCCG
ATTGCAAGTTCGAGCAATTGATTGATCTGTGCGGCGTCGACTATTCTGCCTATGGCGCCACGGGCTCGGAAGGACCGCGC
TACGCCGTGGTTTCCCATTTGCTCTCCGTTTCCCTCAACCAGCGGTTGCGCGTGAAGGTGTTCTGCTCCGACGACGACTT
TCCCATCGTCGCCTCGGTTACCGACATCTGGAACTCGGCCAACTGGTTTGAGCGCGAGGCATTCGATCTGTTCGGCATCG
TGTTTGACGGGCACAACGATCTGCGCCGCATCCTGACCGATTACGGATTCATCGGCCACCCGTTCCGCAAGGACTTCCCC
TTGTCCGGCCATGTCGAGATGCGCTATGACGCCGACCAGCGTCGCGTGATCTATGAGCCCGTGACCATCGAGCCGCGCGA
AGTGACGCCGCGCATCATCCGCGAAGACAAGTACGGAGGCCTGCACTGA

Upstream 100 bases:

>100_bases
GGTTGTCCTCCGACGGCCGAGGCGCTGATCTACGGGATCATTCAGCTGCAACAGAAGATCCGCCGCACCCACACCATTGC
GCGCGCCTGAAGGGACGAAG

Downstream 100 bases:

>100_bases
GGCGGCATGCCGCTTGGTGATCGACCATGGCTGAAATCAAGAACTACTCCCTGAACTTCGGACCGCAGCACCCGGCAGCA
CACGGCGTGCTGCGCTTGGT

Product: NADH (or f420h2) dehydrogenase subunit c

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C [H]

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:

>202_residues
MTAIAIHPESLRDVVASALGDRVRQISVALDEVTVVVSAARYLEAMQILRDAPDCKFEQLIDLCGVDYSAYGATGSEGPR
YAVVSHLLSVSLNQRLRVKVFCSDDDFPIVASVTDIWNSANWFEREAFDLFGIVFDGHNDLRRILTDYGFIGHPFRKDFP
LSGHVEMRYDADQRRVIYEPVTIEPREVTPRIIREDKYGGLH

Sequences:

>Translated_202_residues
MTAIAIHPESLRDVVASALGDRVRQISVALDEVTVVVSAARYLEAMQILRDAPDCKFEQLIDLCGVDYSAYGATGSEGPR
YAVVSHLLSVSLNQRLRVKVFCSDDDFPIVASVTDIWNSANWFEREAFDLFGIVFDGHNDLRRILTDYGFIGHPFRKDFP
LSGHVEMRYDADQRRVIYEPVTIEPREVTPRIIREDKYGGLH
>Mature_201_residues
TAIAIHPESLRDVVASALGDRVRQISVALDEVTVVVSAARYLEAMQILRDAPDCKFEQLIDLCGVDYSAYGATGSEGPRY
AVVSHLLSVSLNQRLRVKVFCSDDDFPIVASVTDIWNSANWFEREAFDLFGIVFDGHNDLRRILTDYGFIGHPFRKDFPL
SGHVEMRYDADQRRVIYEPVTIEPREVTPRIIREDKYGGLH

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=172, Percent_Identity=42.4418604651163, Blast_Score=144, Evalue=4e-35,
Organism=Escherichia coli, GI145693162, Length=127, Percent_Identity=37.007874015748, Blast_Score=85, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI32563621, Length=166, Percent_Identity=38.5542168674699, Blast_Score=127, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI71990788, Length=166, Percent_Identity=38.5542168674699, Blast_Score=126, Evalue=7e-30,
Organism=Drosophila melanogaster, GI24656494, Length=170, Percent_Identity=41.1764705882353, Blast_Score=138, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 22863; Mature: 22732

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAIAIHPESLRDVVASALGDRVRQISVALDEVTVVVSAARYLEAMQILRDAPDCKFEQL
CCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
IDLCGVDYSAYGATGSEGPRYAVVSHLLSVSLNQRLRVKVFCSDDDFPIVASVTDIWNSA
HHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEHHHHHCCC
NWFEREAFDLFGIVFDGHNDLRRILTDYGFIGHPFRKDFPLSGHVEMRYDADQRRVIYEP
CHHHHHHHHEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCEEEECC
VTIEPREVTPRIIREDKYGGLH
CCCCCHHCCHHHHHCCCCCCCC
>Mature Secondary Structure 
TAIAIHPESLRDVVASALGDRVRQISVALDEVTVVVSAARYLEAMQILRDAPDCKFEQL
CEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
IDLCGVDYSAYGATGSEGPRYAVVSHLLSVSLNQRLRVKVFCSDDDFPIVASVTDIWNSA
HHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEHHHHHCCC
NWFEREAFDLFGIVFDGHNDLRRILTDYGFIGHPFRKDFPLSGHVEMRYDADQRRVIYEP
CHHHHHHHHEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCEEEECC
VTIEPREVTPRIIREDKYGGLH
CCCCCHHCCHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA