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The map label for this gene is obgE [H]

Identifier: 222109987

GI number: 222109987

Start: 799732

End: 800805

Strand: Direct

Name: obgE [H]

Synonym: Dtpsy_0772

Alternate gene names: 222109987

Gene position: 799732-800805 (Clockwise)

Preceding gene: 222109986

Following gene: 222109988

Centisome position: 21.06

GC content: 64.34

Gene sequence:

>1074_bases
ATGAAGTTCGTCGACGAAGCCTTTATTGACGTAGCCGCCGGTGACGGTGGCAACGGCTGTGTCTCCTTCCGGCACGAGAA
ATACAAGGAGTTCGGGGGGCCCGACGGTGGAGACGGCGGGCGTGGGGGGCATGTGTTCGCCGTGGCGGATCCCAATCTCA
ATACGTTGGTGGACTTCCGTTATTCACGCCGGCACGAGGCCAAGCGTGGCGAGCACGGCAAGGGCTCCGATATGTTCGGT
GCCGCGGGTTCCGATATCACGCTCAAGATGCCCGTGGGCACCATCATCAGCGATGCCGACACGGGCGAGGTGCTGTTCGA
ACTGTTGACGCCGGGCGAGGTCATCACCATCGCCAAGGGCGGCGACGGTGGTTTTGGCAACATGCGTTTCAAGAGCGCGA
TCAACCGTGCGCCGCGGCAAAAGACGCCCGGCTGGCCCGGCGAGCGTCGCAACCTCAAGCTGGAGCTGAAGGTGCTGGCC
GATGTGGGCCTGCTGGGCATGCCGAACGCCGGTAAGTCCACTTTCATTGCGGCGGTGTCGAACGCGCGGCCCAAGATTGC
CGACTACCCTTTCACGACGTTGCACCCCAACCTGGGCGTAGTACGCGTGGGGCCGGAGCAGAGCTTCGTCGTCGCCGACA
TTCCCGGCCTGATCGAAGGGGCCTCCGAGGGCGCTGGCCTGGGGCACCAGTTCCTGCGCCACCTGCAGCGCACACGGCTG
CTGCTGCACGTGGTGGACCTCGCGCCCTTCGACGAAGCGGTAGACCCGGTGGCCCAGGCCAAGGCCATCGTGGGTGAACT
GAAGAAATACGATGCCGGACTGTATGAAAAGCCCCGCTGGCTGGTCCTCAACAAGCTGGACATGGTGCCATCCGAAGAGC
GCGCTGCGCGGGTGAAGGACTTCGTGAAACGCTTCAAATGGAAGGGCCCCGTGTTCGAAATCTCCGCGCTGACGCGCGAA
GGCTGCGAGCCCCTGGTGCAGTCCATCTTCCAGCACGTGCACGCCCAGCAGTTGGCGCAGAATGCGCCGGCTGAGGTGGA
CCCGCGCTTCGCTGGTGAGCCACCGCGTGGGTGA

Upstream 100 bases:

>100_bases
TTTGTTGTTTTCAGCGCCTGGCGCAGCCGCGCGCATGCGTGATGGCGCCCTTTTGCGCACCCTCCGGCGCCCAGGTGCGC
TTTTTGTAAACTGGATACCC

Downstream 100 bases:

>100_bases
TGCGAGGATTGCTATTTAATTTATAGCTGTTGGCGCTTGCCTGACAAGCGCTAGGGCCTAATTTCTTATAAAAATGGTGT
CCAGTGTATTGCGCGACGCG

Product: GTPase obge

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MKFVDEAFIDVAAGDGGNGCVSFRHEKYKEFGGPDGGDGGRGGHVFAVADPNLNTLVDFRYSRRHEAKRGEHGKGSDMFG
AAGSDITLKMPVGTIISDADTGEVLFELLTPGEVITIAKGGDGGFGNMRFKSAINRAPRQKTPGWPGERRNLKLELKVLA
DVGLLGMPNAGKSTFIAAVSNARPKIADYPFTTLHPNLGVVRVGPEQSFVVADIPGLIEGASEGAGLGHQFLRHLQRTRL
LLHVVDLAPFDEAVDPVAQAKAIVGELKKYDAGLYEKPRWLVLNKLDMVPSEERAARVKDFVKRFKWKGPVFEISALTRE
GCEPLVQSIFQHVHAQQLAQNAPAEVDPRFAGEPPRG

Sequences:

>Translated_357_residues
MKFVDEAFIDVAAGDGGNGCVSFRHEKYKEFGGPDGGDGGRGGHVFAVADPNLNTLVDFRYSRRHEAKRGEHGKGSDMFG
AAGSDITLKMPVGTIISDADTGEVLFELLTPGEVITIAKGGDGGFGNMRFKSAINRAPRQKTPGWPGERRNLKLELKVLA
DVGLLGMPNAGKSTFIAAVSNARPKIADYPFTTLHPNLGVVRVGPEQSFVVADIPGLIEGASEGAGLGHQFLRHLQRTRL
LLHVVDLAPFDEAVDPVAQAKAIVGELKKYDAGLYEKPRWLVLNKLDMVPSEERAARVKDFVKRFKWKGPVFEISALTRE
GCEPLVQSIFQHVHAQQLAQNAPAEVDPRFAGEPPRG
>Mature_357_residues
MKFVDEAFIDVAAGDGGNGCVSFRHEKYKEFGGPDGGDGGRGGHVFAVADPNLNTLVDFRYSRRHEAKRGEHGKGSDMFG
AAGSDITLKMPVGTIISDADTGEVLFELLTPGEVITIAKGGDGGFGNMRFKSAINRAPRQKTPGWPGERRNLKLELKVLA
DVGLLGMPNAGKSTFIAAVSNARPKIADYPFTTLHPNLGVVRVGPEQSFVVADIPGLIEGASEGAGLGHQFLRHLQRTRL
LLHVVDLAPFDEAVDPVAQAKAIVGELKKYDAGLYEKPRWLVLNKLDMVPSEERAARVKDFVKRFKWKGPVFEISALTRE
GCEPLVQSIFQHVHAQQLAQNAPAEVDPRFAGEPPRG

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=324, Percent_Identity=41.9753086419753, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI111955139, Length=363, Percent_Identity=35.2617079889807, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI111955063, Length=195, Percent_Identity=36.4102564102564, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI58761500, Length=136, Percent_Identity=30.8823529411765, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1789574, Length=345, Percent_Identity=54.7826086956522, Blast_Score=337, Evalue=5e-94,
Organism=Escherichia coli, GI1787454, Length=138, Percent_Identity=34.0579710144928, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790615, Length=165, Percent_Identity=33.9393939393939, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17508313, Length=329, Percent_Identity=38.9057750759878, Blast_Score=157, Evalue=8e-39,
Organism=Caenorhabditis elegans, GI17552324, Length=314, Percent_Identity=29.2993630573248, Blast_Score=132, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17509631, Length=168, Percent_Identity=32.1428571428571, Blast_Score=75, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6321962, Length=196, Percent_Identity=38.7755102040816, Blast_Score=122, Evalue=7e-29,
Organism=Drosophila melanogaster, GI24585318, Length=307, Percent_Identity=37.785016286645, Blast_Score=168, Evalue=6e-42,
Organism=Drosophila melanogaster, GI20129375, Length=328, Percent_Identity=37.8048780487805, Blast_Score=151, Evalue=7e-37,
Organism=Drosophila melanogaster, GI24640873, Length=133, Percent_Identity=32.3308270676692, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24640877, Length=133, Percent_Identity=32.3308270676692, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24640875, Length=133, Percent_Identity=32.3308270676692, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 38624; Mature: 38624

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFVDEAFIDVAAGDGGNGCVSFRHEKYKEFGGPDGGDGGRGGHVFAVADPNLNTLVDFR
CCCHHHHHEEEECCCCCCCEEECCHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCEEHHH
YSRRHEAKRGEHGKGSDMFGAAGSDITLKMPVGTIISDADTGEVLFELLTPGEVITIAKG
HHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCEECCCCHHHHHHHHCCCCCEEEEEEC
GDGGFGNMRFKSAINRAPRQKTPGWPGERRNLKLELKVLADVGLLGMPNAGKSTFIAAVS
CCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCEEEEEEC
NARPKIADYPFTTLHPNLGVVRVGPEQSFVVADIPGLIEGASEGAGLGHQFLRHLQRTRL
CCCCCCCCCCCEEECCCCCEEEECCCCCEEEECCCHHHCCCCCCCCHHHHHHHHHHHHHH
LLHVVDLAPFDEAVDPVAQAKAIVGELKKYDAGLYEKPRWLVLNKLDMVPSEERAARVKD
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHCCCCCHHHHHHHHH
FVKRFKWKGPVFEISALTREGCEPLVQSIFQHVHAQQLAQNAPAEVDPRFAGEPPRG
HHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKFVDEAFIDVAAGDGGNGCVSFRHEKYKEFGGPDGGDGGRGGHVFAVADPNLNTLVDFR
CCCHHHHHEEEECCCCCCCEEECCHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCEEHHH
YSRRHEAKRGEHGKGSDMFGAAGSDITLKMPVGTIISDADTGEVLFELLTPGEVITIAKG
HHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCEECCCCHHHHHHHHCCCCCEEEEEEC
GDGGFGNMRFKSAINRAPRQKTPGWPGERRNLKLELKVLADVGLLGMPNAGKSTFIAAVS
CCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCEEEEEEC
NARPKIADYPFTTLHPNLGVVRVGPEQSFVVADIPGLIEGASEGAGLGHQFLRHLQRTRL
CCCCCCCCCCCEEECCCCCEEEECCCCCEEEECCCHHHCCCCCCCCHHHHHHHHHHHHHH
LLHVVDLAPFDEAVDPVAQAKAIVGELKKYDAGLYEKPRWLVLNKLDMVPSEERAARVKD
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHCCCCCHHHHHHHHH
FVKRFKWKGPVFEISALTREGCEPLVQSIFQHVHAQQLAQNAPAEVDPRFAGEPPRG
HHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA