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The map label for this gene is pdxA [H]

Identifier: 222109965

GI number: 222109965

Start: 778972

End: 780027

Strand: Direct

Name: pdxA [H]

Synonym: Dtpsy_0750

Alternate gene names: 222109965

Gene position: 778972-780027 (Clockwise)

Preceding gene: 222109964

Following gene: 222109967

Centisome position: 20.52

GC content: 70.17

Gene sequence:

>1056_bases
ATGAATGCACTTCCCGCGCTTGCCATCACCCAGGGGGATCCCGCAGGCATCGGTCCGGAAATCGTGGCCAAGGCGTTTCG
CGATGCGCCACAGGTGCTGCGCGGCTGCTTCGTCGTGGGAGACCTGCCGACCATGCGCCGTGCGGCGTCCTGCATCATGC
GGCCGGGCCAGCCCAGTTTGCCCGTGGCGCGCCTGGATGCGCACCGTGCGCCGGTCGACCTGGCCGACATTCCGCCGCGC
TGCCTGCCCGTATGGCAACTGCCGGAATTGGAGGGGGTGGCCCCTGCGCCCTGGGGGCGGGTGAGCGCCGAAGCCGGGCG
TGCCGCGGCGGCGTGCGTGGTGTGGGCTGCGCGTGCTGCATTGCGTGGCGAGGTTGCTGCGCTGGTGACGGCGCCTTTGC
ACAAGGAGGCGCTCGCGGCCGCGGGCGTGCACCATCCCGGTCACACGGAACTGCTGCAAGCCGAGGCAGCGCTCCATGCG
GGCGTGTCCTTGCAGCAGATGCCCGTGCGCATGATGCTCGCGAATGACGAGCTGCGCACCGTGCTCGTCAGTATCCACGT
CGCGCTGCGCGATGCCATTACCGCGGTGACGCAGGACAGCGTGCTGCAGACGCTGCGGATCACCCATGCCGCGCTCTCGC
GCAGCCTGGGGCGCGCTCCGCGCATCGGCGTGGCGGGGCTCAATCCGCATGCGGGCGAGGGGGGCTTGTTCGGCCGCGAG
GAGCTCGAAATCATCGCGCCGGCCGTGACGCGGGCGCGCAGTGAGGGGATCGATGCCCACGGCCCGTTTGCACCCGACAC
CATTTTCATGCGCGCCCGCTCCACGCCGCAGCGCGCCGGCGAGTTTGACGTGGTGCTGGCCATGTACCACGACCAGGGCC
TGATCCCGGTGAAGTATTTGGGCGTGGACAAGGGGGTGAACGTTACGCTCGGGTTGCCGCTTGTGCGCACCAGCCCTGAC
CACGGCACGGCCTTCGACATCGCGGGGCAGGGGACGGCGGATGCGGAGAGCCTGATCGAAGCCGTGCGCATGGCGCGGCA
GTTGGCGCGGCCCTGA

Upstream 100 bases:

>100_bases
TCGATATCGACAATCCTGCTTGATTTTTTGCTACTGAAAGTATAGCTGCTTGCGCTTTATGGTAGAGCGCTAGGGCCCTA
TTTGATCTATAGGCTTGTTC

Downstream 100 bases:

>100_bases
ACGTCTCCCTGAAATGCAAAGGCCCGCCGCCCGGGGAGGGCGGTGGGCCTTTTTACGCGCCCTCTGGCGTGCTGTCAGCG
CTTGAGGCTGTCGCGGATCT

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MNALPALAITQGDPAGIGPEIVAKAFRDAPQVLRGCFVVGDLPTMRRAASCIMRPGQPSLPVARLDAHRAPVDLADIPPR
CLPVWQLPELEGVAPAPWGRVSAEAGRAAAACVVWAARAALRGEVAALVTAPLHKEALAAAGVHHPGHTELLQAEAALHA
GVSLQQMPVRMMLANDELRTVLVSIHVALRDAITAVTQDSVLQTLRITHAALSRSLGRAPRIGVAGLNPHAGEGGLFGRE
ELEIIAPAVTRARSEGIDAHGPFAPDTIFMRARSTPQRAGEFDVVLAMYHDQGLIPVKYLGVDKGVNVTLGLPLVRTSPD
HGTAFDIAGQGTADAESLIEAVRMARQLARP

Sequences:

>Translated_351_residues
MNALPALAITQGDPAGIGPEIVAKAFRDAPQVLRGCFVVGDLPTMRRAASCIMRPGQPSLPVARLDAHRAPVDLADIPPR
CLPVWQLPELEGVAPAPWGRVSAEAGRAAAACVVWAARAALRGEVAALVTAPLHKEALAAAGVHHPGHTELLQAEAALHA
GVSLQQMPVRMMLANDELRTVLVSIHVALRDAITAVTQDSVLQTLRITHAALSRSLGRAPRIGVAGLNPHAGEGGLFGRE
ELEIIAPAVTRARSEGIDAHGPFAPDTIFMRARSTPQRAGEFDVVLAMYHDQGLIPVKYLGVDKGVNVTLGLPLVRTSPD
HGTAFDIAGQGTADAESLIEAVRMARQLARP
>Mature_351_residues
MNALPALAITQGDPAGIGPEIVAKAFRDAPQVLRGCFVVGDLPTMRRAASCIMRPGQPSLPVARLDAHRAPVDLADIPPR
CLPVWQLPELEGVAPAPWGRVSAEAGRAAAACVVWAARAALRGEVAALVTAPLHKEALAAAGVHHPGHTELLQAEAALHA
GVSLQQMPVRMMLANDELRTVLVSIHVALRDAITAVTQDSVLQTLRITHAALSRSLGRAPRIGVAGLNPHAGEGGLFGRE
ELEIIAPAVTRARSEGIDAHGPFAPDTIFMRARSTPQRAGEFDVVLAMYHDQGLIPVKYLGVDKGVNVTLGLPLVRTSPD
HGTAFDIAGQGTADAESLIEAVRMARQLARP

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=349, Percent_Identity=37.8223495702006, Blast_Score=204, Evalue=9e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 36917; Mature: 36917

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNALPALAITQGDPAGIGPEIVAKAFRDAPQVLRGCFVVGDLPTMRRAASCIMRPGQPSL
CCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHCCCCCCCC
PVARLDAHRAPVDLADIPPRCLPVWQLPELEGVAPAPWGRVSAEAGRAAAACVVWAARAA
CHHHHCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHH
LRGEVAALVTAPLHKEALAAAGVHHPGHTELLQAEAALHAGVSLQQMPVRMMLANDELRT
HHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHCCEEEEECCHHHHH
VLVSIHVALRDAITAVTQDSVLQTLRITHAALSRSLGRAPRIGVAGLNPHAGEGGLFGRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCH
ELEIIAPAVTRARSEGIDAHGPFAPDTIFMRARSTPQRAGEFDVVLAMYHDQGLIPVKYL
HHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEEECCCCCCEEEEE
GVDKGVNVTLGLPLVRTSPDHGTAFDIAGQGTADAESLIEAVRMARQLARP
CCCCCCEEEECCEEEEECCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNALPALAITQGDPAGIGPEIVAKAFRDAPQVLRGCFVVGDLPTMRRAASCIMRPGQPSL
CCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHCCCCCCCC
PVARLDAHRAPVDLADIPPRCLPVWQLPELEGVAPAPWGRVSAEAGRAAAACVVWAARAA
CHHHHCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHH
LRGEVAALVTAPLHKEALAAAGVHHPGHTELLQAEAALHAGVSLQQMPVRMMLANDELRT
HHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHCCEEEEECCHHHHH
VLVSIHVALRDAITAVTQDSVLQTLRITHAALSRSLGRAPRIGVAGLNPHAGEGGLFGRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCH
ELEIIAPAVTRARSEGIDAHGPFAPDTIFMRARSTPQRAGEFDVVLAMYHDQGLIPVKYL
HHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEEECCCCCCEEEEE
GVDKGVNVTLGLPLVRTSPDHGTAFDIAGQGTADAESLIEAVRMARQLARP
CCCCCCEEEECCEEEEECCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA