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The map label for this gene is mlaC [H]

Identifier: 222109935

GI number: 222109935

Start: 751851

End: 752498

Strand: Direct

Name: mlaC [H]

Synonym: Dtpsy_0720

Alternate gene names: 222109935

Gene position: 751851-752498 (Clockwise)

Preceding gene: 222109934

Following gene: 222109936

Centisome position: 19.8

GC content: 66.98

Gene sequence:

>648_bases
ATGATGAACCGCCGTACCCTGATCCATGCCGCCGCCGCGATGGCGGTGGCCACGTGGGTGGCCGTGCCCCAGGCCGCGCT
GGCGGCCGACGAGGCACCGGATGCCCTCGTCAAGCGCCTCTCGGTCGATGTGCTGGAGACGCTGCGCAAAGACAAATCCA
TCAAGGCCGGCGACGTGGACCGCATCATGGCGCTGGTGGACAAGACCATCCTGCCCCACGTGAACTTCCGCCGCATGACG
GCAGCGTCCGTCGGGCCGGGCTGGCGCAAGGCTACGCCGGAGCAGCAGGCGCGCCTGCAGGACGAGTTCAAGACACTGCT
GGTGCGCACTTACGCGGGCGCGCTCAGCCAGGTCACGGACCAGAGCATCGTTGTGAAGCCGCTGCGCGCAGCCGCCGAAG
ACAAGGACGTGCTCGTGCGCACCGAAATCCGCGGCCGGGGCGACCCGATACAACTGGACTACCGTCTGGAGAAGACGCCG
GGCGAGGGTGCGGGCTGGAAAATCTACAACCTCAACGTTCTGGGGGTGTGGCTGGTGGAAACCTACCGCAGCCAGTTCGC
GCAGGAGATCAACGCCAAGGGCGTGGATGGCCTGATCGAGGCGCTGGTGGCGCGCAACAAGGCCAACGCCGCCTCCAGCG
CCAAGTAA

Upstream 100 bases:

>100_bases
GGCGGCGACGCATGTGCAGCGCGGGGCGCCCTCCACAATCTACCCAACGAAACCAGATATGGCAGCGCACGGCGTGGCGC
TGCACGCAAGGAGCCTCACC

Downstream 100 bases:

>100_bases
CCAGAACAGCAACAGAAAGAAGCGAAAGGCCTGTGCATGCTGGTGCTGCCCGCTGAACTCACCCACCGCCACGCTGGCGC
CACCCTGCGCATGCTGCTGC

Product: toluene tolerance family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MMNRRTLIHAAAAMAVATWVAVPQAALAADEAPDALVKRLSVDVLETLRKDKSIKAGDVDRIMALVDKTILPHVNFRRMT
AASVGPGWRKATPEQQARLQDEFKTLLVRTYAGALSQVTDQSIVVKPLRAAAEDKDVLVRTEIRGRGDPIQLDYRLEKTP
GEGAGWKIYNLNVLGVWLVETYRSQFAQEINAKGVDGLIEALVARNKANAASSAK

Sequences:

>Translated_215_residues
MMNRRTLIHAAAAMAVATWVAVPQAALAADEAPDALVKRLSVDVLETLRKDKSIKAGDVDRIMALVDKTILPHVNFRRMT
AASVGPGWRKATPEQQARLQDEFKTLLVRTYAGALSQVTDQSIVVKPLRAAAEDKDVLVRTEIRGRGDPIQLDYRLEKTP
GEGAGWKIYNLNVLGVWLVETYRSQFAQEINAKGVDGLIEALVARNKANAASSAK
>Mature_215_residues
MMNRRTLIHAAAAMAVATWVAVPQAALAADEAPDALVKRLSVDVLETLRKDKSIKAGDVDRIMALVDKTILPHVNFRRMT
AASVGPGWRKATPEQQARLQDEFKTLLVRTYAGALSQVTDQSIVVKPLRAAAEDKDVLVRTEIRGRGDPIQLDYRLEKTP
GEGAGWKIYNLNVLGVWLVETYRSQFAQEINAKGVDGLIEALVARNKANAASSAK

Specific function: Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. May transfer phospholipid across the peripl

COG id: COG2854

COG function: function code Q; ABC-type transport system involved in resistance to organic solvents, auxiliary component

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaC/ttg2D family [H]

Homologues:

Organism=Escherichia coli, GI1789583, Length=194, Percent_Identity=27.319587628866, Blast_Score=70, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023094
- InterPro:   IPR008869 [H]

Pfam domain/function: PF05494 Tol_Tol_Ttg2 [H]

EC number: NA

Molecular weight: Translated: 23527; Mature: 23527

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNRRTLIHAAAAMAVATWVAVPQAALAADEAPDALVKRLSVDVLETLRKDKSIKAGDVD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHH
RIMALVDKTILPHVNFRRMTAASVGPGWRKATPEQQARLQDEFKTLLVRTYAGALSQVTD
HHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QSIVVKPLRAAAEDKDVLVRTEIRGRGDPIQLDYRLEKTPGEGAGWKIYNLNVLGVWLVE
CHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEEEECCCCCCCCEEEEEEEEHHHHHHH
TYRSQFAQEINAKGVDGLIEALVARNKANAASSAK
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MMNRRTLIHAAAAMAVATWVAVPQAALAADEAPDALVKRLSVDVLETLRKDKSIKAGDVD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHH
RIMALVDKTILPHVNFRRMTAASVGPGWRKATPEQQARLQDEFKTLLVRTYAGALSQVTD
HHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QSIVVKPLRAAAEDKDVLVRTEIRGRGDPIQLDYRLEKTPGEGAGWKIYNLNVLGVWLVE
CHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEEEECCCCCCCCEEEEEEEEHHHHHHH
TYRSQFAQEINAKGVDGLIEALVARNKANAASSAK
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]