Click here to switch to the map view.

The map label for this gene is gltK [H]

Identifier: 222109806

GI number: 222109806

Start: 610220

End: 610891

Strand: Direct

Name: gltK [H]

Synonym: Dtpsy_0590

Alternate gene names: 222109806

Gene position: 610220-610891 (Clockwise)

Preceding gene: 222109805

Following gene: 222109807

Centisome position: 16.07

GC content: 62.05

Gene sequence:

>672_bases
ATGAATCTGAATATCGATTGGTCCTTCTTCACCTGGGAGCTGTTCAGCAACTTCGTGATCAAGGGGCTGTACTTCAGCCT
GGTGCTGACGGTGATCGCCACCGTGGGCGGCATCCTGCTGGGCACGGTGCTGGCGCTCATGCGCCTGTCGGGCAAGAAGT
GGCTGGACGTGCCGGCCACCATCTATGTCAACGGCATGCGCTCGATTCCCCTGGTGATGGTGATCCTGTGGTTCTTCCTG
CTGGTGCCCATGATCATCGGTCGCCCCATCGGCGCCGAGGTGTCGGCCGTGGTGACCTTCATCGCCTTCGAAGCCGCCTA
CTTCAGCGAGATCATGCGCGCAGGCATCCAGTCCATCCCGCGCGGCCAGGTGTTCGCGGGGCAGGCGCTGGGCATGACCT
ACGGGCAGAACATGCGCCTAGTGGTGCTGCCGCAGGCCTTCCGCAACATGCTGCCGGTGCTGCTCACGCAGACCATCATC
CTGTTCCAGGACACGTCGCTGGTGTACGCCATCGGTGCCTACGACATGCTCAAGGGCTTCGAGATCGCGGGCAAGAACTA
TGGCCGCCCGATCGAGGCCTACCTGGCCGCGGCCGTGGTCTATTTCATCCTCTGCTACGCGCTGTCCTGGCTGGTCAAGC
GCCTGCACAAGAAGATCGCCATCATTCGCTGA

Upstream 100 bases:

>100_bases
TACATCATCTCGGCCTTTGCCATCAACCGCATCATGGCGTTCATCGAAAAGCGCACGCGGGTGCCGGGCCTGATTGCCGC
AGGCGGGGGAGGACACTGAT

Downstream 100 bases:

>100_bases
AGCGGCGTTCCAAGGAATTGCAATGATTGAATTGAAGAACGTTTCCAAGTGGTACGGCAGCTTCCAGGTGCTCACGGACT
GCTCCACGAACATCCAGAAG

Product: polar amino acid ABC transporter inner membrane subunit

Products: ADP; phosphate; L-glutamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MNLNIDWSFFTWELFSNFVIKGLYFSLVLTVIATVGGILLGTVLALMRLSGKKWLDVPATIYVNGMRSIPLVMVILWFFL
LVPMIIGRPIGAEVSAVVTFIAFEAAYFSEIMRAGIQSIPRGQVFAGQALGMTYGQNMRLVVLPQAFRNMLPVLLTQTII
LFQDTSLVYAIGAYDMLKGFEIAGKNYGRPIEAYLAAAVVYFILCYALSWLVKRLHKKIAIIR

Sequences:

>Translated_223_residues
MNLNIDWSFFTWELFSNFVIKGLYFSLVLTVIATVGGILLGTVLALMRLSGKKWLDVPATIYVNGMRSIPLVMVILWFFL
LVPMIIGRPIGAEVSAVVTFIAFEAAYFSEIMRAGIQSIPRGQVFAGQALGMTYGQNMRLVVLPQAFRNMLPVLLTQTII
LFQDTSLVYAIGAYDMLKGFEIAGKNYGRPIEAYLAAAVVYFILCYALSWLVKRLHKKIAIIR
>Mature_223_residues
MNLNIDWSFFTWELFSNFVIKGLYFSLVLTVIATVGGILLGTVLALMRLSGKKWLDVPATIYVNGMRSIPLVMVILWFFL
LVPMIIGRPIGAEVSAVVTFIAFEAAYFSEIMRAGIQSIPRGQVFAGQALGMTYGQNMRLVVLPQAFRNMLPVLLTQTII
LFQDTSLVYAIGAYDMLKGFEIAGKNYGRPIEAYLAAAVVYFILCYALSWLVKRLHKKIAIIR

Specific function: Part of the binding-protein-dependent transport system for aspartate/glutamate; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786873, Length=224, Percent_Identity=48.2142857142857, Blast_Score=183, Evalue=1e-47,
Organism=Escherichia coli, GI87082239, Length=215, Percent_Identity=31.6279069767442, Blast_Score=113, Evalue=9e-27,
Organism=Escherichia coli, GI1787030, Length=222, Percent_Identity=32.4324324324324, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788226, Length=205, Percent_Identity=33.6585365853659, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1786874, Length=194, Percent_Identity=28.8659793814433, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1788645, Length=226, Percent_Identity=26.5486725663717, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI48994930, Length=124, Percent_Identity=35.4838709677419, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788646, Length=217, Percent_Identity=24.8847926267281, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787087, Length=115, Percent_Identity=33.9130434782609, Blast_Score=68, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24946; Mature: 24946

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLNIDWSFFTWELFSNFVIKGLYFSLVLTVIATVGGILLGTVLALMRLSGKKWLDVPAT
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCE
IYVNGMRSIPLVMVILWFFLLVPMIIGRPIGAEVSAVVTFIAFEAAYFSEIMRAGIQSIP
EEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RGQVFAGQALGMTYGQNMRLVVLPQAFRNMLPVLLTQTIILFQDTSLVYAIGAYDMLKGF
CCCEECCHHHCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHEECCCCEEEHHHHHHHHHH
EIAGKNYGRPIEAYLAAAVVYFILCYALSWLVKRLHKKIAIIR
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNLNIDWSFFTWELFSNFVIKGLYFSLVLTVIATVGGILLGTVLALMRLSGKKWLDVPAT
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCE
IYVNGMRSIPLVMVILWFFLLVPMIIGRPIGAEVSAVVTFIAFEAAYFSEIMRAGIQSIP
EEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RGQVFAGQALGMTYGQNMRLVVLPQAFRNMLPVLLTQTIILFQDTSLVYAIGAYDMLKGF
CCCEECCHHHCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHEECCCCEEEHHHHHHHHHH
EIAGKNYGRPIEAYLAAAVVYFILCYALSWLVKRLHKKIAIIR
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamate [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamate [Periplasm] + H2O = ADP + phosphate + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]