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The map label for this gene is gltJ [H]

Identifier: 222109805

GI number: 222109805

Start: 609466

End: 610218

Strand: Direct

Name: gltJ [H]

Synonym: Dtpsy_0589

Alternate gene names: 222109805

Gene position: 609466-610218 (Clockwise)

Preceding gene: 222109804

Following gene: 222109806

Centisome position: 16.05

GC content: 62.42

Gene sequence:

>753_bases
ATGAATTGGGATTGGCAGGTGTTCTGCCAGGACACCATTACCCAAGAGGTCGGTCAAAGCTGCTTCGGCAAGAACGGCGA
CATCACCTACCTCGACTGGATGCTGTCAGCCTGGGGCTGGACGGTATCCGTTTCCTTGCTGTCGCTGGCCGTTGCGCTGG
TGGTCGGTTCGCTGGTCGGCACGCTGCGCACGCTGGAAGGCCGTCCATGGACGGTGCGCCTGGGCAACGCCTGGGTCGAG
CTGTTTCGCAACATTCCGCTGCTGGTGCACATCTTTGTGTGGTACCACGTGGTGCCGTCGATTTTCCCGGCCATGAAGTC
GCTGCCGGGCTTCGTGCTGGTGGTGTTTGCGCTGGGCTTTTTCACCTCGGCGCGTATCGCCGAGCAGGTGCGCTCGGGCA
TTCAGGCGCTGCCGCGCGGCCAGCGCTATGCGGGCATGGCGCTGGGCTTCACCACGTTCCAGTACTACCGCTACGTGCTG
CTGCCGATGGCGTTTCGCATCATCATCCCGCCGCTCACCAGCGAGACCATGAACGTGTTCAAGAACTCGTCGGTGGCGTT
TGCCGTTTCGGTGGCCGAGCTGACCATGTTTGCCATGCAGGCGCAGGAAGAGACTTCACGCGGCATCGAGGTGTACCTGG
CCGTCACGGCGCTGTACATCATCTCGGCCTTTGCCATCAACCGCATCATGGCGTTCATCGAAAAGCGCACGCGGGTGCCG
GGCCTGATTGCCGCAGGCGGGGGAGGACACTGA

Upstream 100 bases:

>100_bases
CCTTCGGCCTCTGGGCCCGAAGGGGCGTTTTTTGTTGTTGCGCCAGCGCCGCCATGTGCCGCCGCGGCAACACGGATCGA
AGAATAGAAGGGGTGCTCCT

Downstream 100 bases:

>100_bases
TATGAATCTGAATATCGATTGGTCCTTCTTCACCTGGGAGCTGTTCAGCAACTTCGTGATCAAGGGGCTGTACTTCAGCC
TGGTGCTGACGGTGATCGCC

Product: polar amino acid ABC transporter inner membrane subunit

Products: ADP; phosphate; L-glutamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MNWDWQVFCQDTITQEVGQSCFGKNGDITYLDWMLSAWGWTVSVSLLSLAVALVVGSLVGTLRTLEGRPWTVRLGNAWVE
LFRNIPLLVHIFVWYHVVPSIFPAMKSLPGFVLVVFALGFFTSARIAEQVRSGIQALPRGQRYAGMALGFTTFQYYRYVL
LPMAFRIIIPPLTSETMNVFKNSSVAFAVSVAELTMFAMQAQEETSRGIEVYLAVTALYIISAFAINRIMAFIEKRTRVP
GLIAAGGGGH

Sequences:

>Translated_250_residues
MNWDWQVFCQDTITQEVGQSCFGKNGDITYLDWMLSAWGWTVSVSLLSLAVALVVGSLVGTLRTLEGRPWTVRLGNAWVE
LFRNIPLLVHIFVWYHVVPSIFPAMKSLPGFVLVVFALGFFTSARIAEQVRSGIQALPRGQRYAGMALGFTTFQYYRYVL
LPMAFRIIIPPLTSETMNVFKNSSVAFAVSVAELTMFAMQAQEETSRGIEVYLAVTALYIISAFAINRIMAFIEKRTRVP
GLIAAGGGGH
>Mature_250_residues
MNWDWQVFCQDTITQEVGQSCFGKNGDITYLDWMLSAWGWTVSVSLLSLAVALVVGSLVGTLRTLEGRPWTVRLGNAWVE
LFRNIPLLVHIFVWYHVVPSIFPAMKSLPGFVLVVFALGFFTSARIAEQVRSGIQALPRGQRYAGMALGFTTFQYYRYVL
LPMAFRIIIPPLTSETMNVFKNSSVAFAVSVAELTMFAMQAQEETSRGIEVYLAVTALYIISAFAINRIMAFIEKRTRVP
GLIAAGGGGH

Specific function: Part of the binding-protein-dependent transport system for aspartate/glutamate; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786874, Length=251, Percent_Identity=37.8486055776892, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1787030, Length=200, Percent_Identity=31, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI48994930, Length=133, Percent_Identity=37.593984962406, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1788226, Length=213, Percent_Identity=29.5774647887324, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786873, Length=212, Percent_Identity=24.5283018867925, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI87082239, Length=161, Percent_Identity=27.9503105590062, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788645, Length=163, Percent_Identity=28.2208588957055, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787086, Length=215, Percent_Identity=25.5813953488372, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 27804; Mature: 27804

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EEEECCCCCC
>Mature Secondary Structure
MNWDWQVFCQDTITQEVGQSCFGKNGDITYLDWMLSAWGWTVSVSLLSLAVALVVGSLVG
CCCCCEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLRTLEGRPWTVRLGNAWVELFRNIPLLVHIFVWYHVVPSIFPAMKSLPGFVLVVFALGF
HHHHCCCCCEEEEECHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
FTSARIAEQVRSGIQALPRGQRYAGMALGFTTFQYYRYVLLPMAFRIIIPPLTSETMNVF
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
KNSSVAFAVSVAELTMFAMQAQEETSRGIEVYLAVTALYIISAFAINRIMAFIEKRTRVP
CCCCHHEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GLIAAGGGGH
EEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamate [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamate [Periplasm] + H2O = ADP + phosphate + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]