Click here to switch to the map view.

The map label for this gene is plsC [H]

Identifier: 222109762

GI number: 222109762

Start: 565942

End: 566691

Strand: Direct

Name: plsC [H]

Synonym: Dtpsy_0546

Alternate gene names: 222109762

Gene position: 565942-566691 (Clockwise)

Preceding gene: 222109761

Following gene: 222109763

Centisome position: 14.91

GC content: 69.07

Gene sequence:

>750_bases
ATGGCACTGATCCGCTCCATTCTTCATTTGTTGGTGATGGTCGTCACCGTAGTCCCCTACACCCTGGGCATCTTGCTGGT
GCGTGTGCTGGGCGGCAGCCCGGCGGCGCGCTACCGCGTGGCGCGCGCCTGGCTGAAGCTGTGCATCGACTCGGCGCGCT
GGCTGCTGGGCATCCGCACGCAGATCACCGGCATGGAGCACCTGCCCCAGGGCGAGCAGCAGGGCGCGGTGCTGCTGGTC
AAGCACCAGTCCACCTACGAGACCTTCCTGATGCCGGCGATCATGCCGCACCCGCTGGCCTACGTGTTCAAGAAGGAACT
GCTCTCGGTGCCGTTTTTCGGCTGGTCCATCGGCAGCCTGGACATGATCCACATCGACCGCGGCCAGCGCGCCCGCGCCT
TCGCCAAGGTGCTGCAGCAAGGCCGCCGCCTGTTGGCCAAGGGCACCTGGGTCATCATGTTTCCCGAGGGCACGCGCACG
GAACGCGGCGCCAAGGGCGACTACAAGAGCGGCGGCACGCGCCTGGCCATCGACGCCGGCGTGCCCGTGGTGCCGATCGC
CGTGACCTCGGCCACGGTCTGGCCGCGCAAGGCCTTCATCAAGCGTCCGGGGGTGGTGCACGTGTCCGTCGGCCGGCCCA
TCCCCACCGAGGGGCGCAAGCCTGACGAGCTGATGCGCGAGGTCGAGGCCTGGATCGAGGGCGAGATGCGCCGCCTGGAC
CCCGACGCCTACCCCCCCACCGCCGGCTGA

Upstream 100 bases:

>100_bases
CCAGCCTGCCCGTGGCCCTGTGATGCGAAGACTATTGAATTGATAGCTGCTCGCGCTTACTGCATGGGCGCTAGAGGCCA
AAAACACTGAAAATTGCTTC

Downstream 100 bases:

>100_bases
CATGCAGCGGCTGGTGCAGCTGGCGCTGGACTTCCTGGGCGGCGGGAGCAGCCCGGATTCCGGGGTGCCACAGCCGAAAC
GGGCGATGGCGCCCGTCCAG

Product: phospholipid/glycerol acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MALIRSILHLLVMVVTVVPYTLGILLVRVLGGSPAARYRVARAWLKLCIDSARWLLGIRTQITGMEHLPQGEQQGAVLLV
KHQSTYETFLMPAIMPHPLAYVFKKELLSVPFFGWSIGSLDMIHIDRGQRARAFAKVLQQGRRLLAKGTWVIMFPEGTRT
ERGAKGDYKSGGTRLAIDAGVPVVPIAVTSATVWPRKAFIKRPGVVHVSVGRPIPTEGRKPDELMREVEAWIEGEMRRLD
PDAYPPTAG

Sequences:

>Translated_249_residues
MALIRSILHLLVMVVTVVPYTLGILLVRVLGGSPAARYRVARAWLKLCIDSARWLLGIRTQITGMEHLPQGEQQGAVLLV
KHQSTYETFLMPAIMPHPLAYVFKKELLSVPFFGWSIGSLDMIHIDRGQRARAFAKVLQQGRRLLAKGTWVIMFPEGTRT
ERGAKGDYKSGGTRLAIDAGVPVVPIAVTSATVWPRKAFIKRPGVVHVSVGRPIPTEGRKPDELMREVEAWIEGEMRRLD
PDAYPPTAG
>Mature_248_residues
ALIRSILHLLVMVVTVVPYTLGILLVRVLGGSPAARYRVARAWLKLCIDSARWLLGIRTQITGMEHLPQGEQQGAVLLVK
HQSTYETFLMPAIMPHPLAYVFKKELLSVPFFGWSIGSLDMIHIDRGQRARAFAKVLQQGRRLLAKGTWVIMFPEGTRTE
RGAKGDYKSGGTRLAIDAGVPVVPIAVTSATVWPRKAFIKRPGVVHVSVGRPIPTEGRKPDELMREVEAWIEGEMRRLDP
DAYPPTAG

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=181, Percent_Identity=32.0441988950276, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI15100175, Length=181, Percent_Identity=32.0441988950276, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI6041665, Length=171, Percent_Identity=26.9005847953216, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1789395, Length=176, Percent_Identity=30.1136363636364, Blast_Score=73, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17564032, Length=221, Percent_Identity=28.0542986425339, Blast_Score=81, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6320151, Length=250, Percent_Identity=27.6, Blast_Score=82, Evalue=7e-17,
Organism=Drosophila melanogaster, GI281364648, Length=203, Percent_Identity=24.6305418719212, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24582856, Length=203, Percent_Identity=24.6305418719212, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24582854, Length=203, Percent_Identity=24.6305418719212, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24641614, Length=173, Percent_Identity=29.4797687861272, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641612, Length=173, Percent_Identity=29.4797687861272, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 27635; Mature: 27504

Theoretical pI: Translated: 10.81; Mature: 10.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALIRSILHLLVMVVTVVPYTLGILLVRVLGGSPAARYRVARAWLKLCIDSARWLLGIRT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QITGMEHLPQGEQQGAVLLVKHQSTYETFLMPAIMPHPLAYVFKKELLSVPFFGWSIGSL
HHCCHHHCCCCCCCCCEEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCE
DMIHIDRGQRARAFAKVLQQGRRLLAKGTWVIMFPEGTRTERGAKGDYKSGGTRLAIDAG
EEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECC
VPVVPIAVTSATVWPRKAFIKRPGVVHVSVGRPIPTEGRKPDELMREVEAWIEGEMRRLD
CCEEEEEEECCCCCHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCHHHHCC
PDAYPPTAG
CCCCCCCCC
>Mature Secondary Structure 
ALIRSILHLLVMVVTVVPYTLGILLVRVLGGSPAARYRVARAWLKLCIDSARWLLGIRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QITGMEHLPQGEQQGAVLLVKHQSTYETFLMPAIMPHPLAYVFKKELLSVPFFGWSIGSL
HHCCHHHCCCCCCCCCEEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCE
DMIHIDRGQRARAFAKVLQQGRRLLAKGTWVIMFPEGTRTERGAKGDYKSGGTRLAIDAG
EEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECC
VPVVPIAVTSATVWPRKAFIKRPGVVHVSVGRPIPTEGRKPDELMREVEAWIEGEMRRLD
CCEEEEEEECCCCCHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCHHHHCC
PDAYPPTAG
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]