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The map label for this gene is gmhB [H]

Identifier: 222109761

GI number: 222109761

Start: 565289

End: 565864

Strand: Direct

Name: gmhB [H]

Synonym: Dtpsy_0545

Alternate gene names: 222109761

Gene position: 565289-565864 (Clockwise)

Preceding gene: 222109760

Following gene: 222109762

Centisome position: 14.89

GC content: 71.53

Gene sequence:

>576_bases
ATGAAACTCGCCATCCTGGACCGAGACGGAACGCTCAACGCGCTGGGCGATGGCTTCATCGCCTCGCCCGACGAATGGGT
GCCGGTGCCTGGCGCGCTGGAGGCCGTGGCGCGGCTGAACCACGCGGGCTGGCATGTGGTGGTGGCCACCAACCAGCCGG
GCCTGGGCCGCGGCCTCTTCGATGCGCAGACCCTGGTGGCCATCCACGCAAAGATGCACCGGCAGCTGGCCACGCTGGGT
GGGCGCATCGACGCGGTGTTCTACTGCCCCCACACCGAGAGCGAGCAATGCCACTGCCGCAAGCCCGCTCCGGGCCTGAT
GGAGCAGATCCGCGATCGCTACGGCGCGGAGGGGCAGGAAATTCTGGTGGCGGGCAGCAGTGCGGCCCACCTGCAGGCGG
CGAGCGAGCTGGGCGCGCAACTGCACATGGTCTGCACCGGTCGCTCGGCCCACCTGGACCCGCGCCAGAGCCTGCCGCCC
GGCTGGCCCGCCGGCACGCGCGCCCATGCCAGCCTGGGCGCGCTGGCGGATTTCATCGCCCCGCAGAACGGTGCCAGCCT
GCCCGTGGCCCTGTGA

Upstream 100 bases:

>100_bases
GCGCCTGGCGGTGTGACCGTGCGCGGCTGTGGGGCCTGGACCGTTACGCCGGTGACGGCGGACGCGGGCGGCGCGGCAGC
GTTGCTTTGATAATCGCGCC

Downstream 100 bases:

>100_bases
TGCGAAGACTATTGAATTGATAGCTGCTCGCGCTTACTGCATGGGCGCTAGAGGCCAAAAACACTGAAAATTGCTTCATG
GCACTGATCCGCTCCATTCT

Product: histidinol-phosphate phosphatase family protein

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MKLAILDRDGTLNALGDGFIASPDEWVPVPGALEAVARLNHAGWHVVVATNQPGLGRGLFDAQTLVAIHAKMHRQLATLG
GRIDAVFYCPHTESEQCHCRKPAPGLMEQIRDRYGAEGQEILVAGSSAAHLQAASELGAQLHMVCTGRSAHLDPRQSLPP
GWPAGTRAHASLGALADFIAPQNGASLPVAL

Sequences:

>Translated_191_residues
MKLAILDRDGTLNALGDGFIASPDEWVPVPGALEAVARLNHAGWHVVVATNQPGLGRGLFDAQTLVAIHAKMHRQLATLG
GRIDAVFYCPHTESEQCHCRKPAPGLMEQIRDRYGAEGQEILVAGSSAAHLQAASELGAQLHMVCTGRSAHLDPRQSLPP
GWPAGTRAHASLGALADFIAPQNGASLPVAL
>Mature_191_residues
MKLAILDRDGTLNALGDGFIASPDEWVPVPGALEAVARLNHAGWHVVVATNQPGLGRGLFDAQTLVAIHAKMHRQLATLG
GRIDAVFYCPHTESEQCHCRKPAPGLMEQIRDRYGAEGQEILVAGSSAAHLQAASELGAQLHMVCTGRSAHLDPRQSLPP
GWPAGTRAHASLGALADFIAPQNGASLPVAL

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=153, Percent_Identity=32.0261437908497, Blast_Score=79, Evalue=1e-16,
Organism=Escherichia coli, GI87082027, Length=139, Percent_Identity=30.9352517985612, Blast_Score=73, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: NA

Molecular weight: Translated: 20109; Mature: 20109

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLAILDRDGTLNALGDGFIASPDEWVPVPGALEAVARLNHAGWHVVVATNQPGLGRGLF
CEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCH
DAQTLVAIHAKMHRQLATLGGRIDAVFYCPHTESEQCHCRKPAPGLMEQIRDRYGAEGQE
HHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCE
ILVAGSSAAHLQAASELGAQLHMVCTGRSAHLDPRQSLPPGWPAGTRAHASLGALADFIA
EEEECCCHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHC
PQNGASLPVAL
CCCCCCCCCCC
>Mature Secondary Structure
MKLAILDRDGTLNALGDGFIASPDEWVPVPGALEAVARLNHAGWHVVVATNQPGLGRGLF
CEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCH
DAQTLVAIHAKMHRQLATLGGRIDAVFYCPHTESEQCHCRKPAPGLMEQIRDRYGAEGQE
HHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCE
ILVAGSSAAHLQAASELGAQLHMVCTGRSAHLDPRQSLPPGWPAGTRAHASLGALADFIA
EEEECCCHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHC
PQNGASLPVAL
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919; 12101286 [H]