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The map label for this gene is corC [H]

Identifier: 222109755

GI number: 222109755

Start: 557547

End: 558425

Strand: Direct

Name: corC [H]

Synonym: Dtpsy_0539

Alternate gene names: 222109755

Gene position: 557547-558425 (Clockwise)

Preceding gene: 222109754

Following gene: 222109756

Centisome position: 14.69

GC content: 68.26

Gene sequence:

>879_bases
GTGTCCGACCCCCACCCTGCGCGCGCCTCCGACAAGGAGGACAAGCGCACGTTCCTGCAGCGCCTCGTCGAGTTCATCAA
CCCCGGGCCGGACTCGACGGCCGAGCTCATCGCCACGCTGGCCGAGGCCGAGGACAACGACGTCATCAACGCCGATGCGC
GGGTGATGCTGGAGCGCGTGCTGCGCATGGCCGAGATGACCGCGGGCGACGTGCTGGTGCCCGCGCCACGCATGGACATG
CTGGACATCGACGCGCCGGTGGATGAGCTCATGCACCAGGTGCTGCATACCGCGCACTCGCGCTTTCCGGTGTACCAGGG
CGAGCGCGACAACATCATCGGCATCCTGCTGGCCAAGGATCTGCTCAAGCTCTGGCGCTCGCCGGGGCTGAACGTGCGCA
CGCTGGTGCGCCCGGCGCTGTTCGTGCCCGAGAGCAAGGGCCTGCATGACCTGGGGCGTGAGTTTCGCAACACGCGCAAC
CACATGGCCATCGCCATCGACGAGTTCGGCCGCATCGCCGGTCTGGTGACGTTCGAGGACGTGATCGAGCAGATCGTGGG
CGAGATCGAGGACGAGTTCGATATCCCCGAGGACGAGGGCGACATCTTCGGCCTGGCCGACCGCACCTTCCGCGTGAGCG
GCGACACGCCCGTGGAGCGCGTGGCCGAGGCCTTCGGCGTGGCGCTGCAGGGCAGCGACCCCGATGAGAGCTTTGACACC
ATCGGCGGCCTGATCGCGCATGAGCTGGGCCGCATGCCGCGCAAGGGAGAGTCCGTGGTGCTCGGCGGCCTGCAGTTTGT
GGTGATGCACACCAAGGGCGGGTCGGTGCGCTGGTTCAAGGTCGCACCGGCGGCGGGCACGCCCGAGTCCGAACGCTGA

Upstream 100 bases:

>100_bases
CACCAGGCCGCCGAGTAGGCAGGCGTGCCCCGCGGGTGCGCGGGGCGATCCGCTATCCTTGGGGGCTGATCCACTCCCTG
CACAACCTGCACCCGTTCCC

Downstream 100 bases:

>100_bases
TGGCCGTCGCACCGCCCTTGGCCGCGCACGCACCGCGCCGCGGCCCGTTGCCCTGGGTGCTGGCACTGGTGGCCGGGCTG
GCGCAGGCCGCATCGCTGGC

Product: cbs domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MSDPHPARASDKEDKRTFLQRLVEFINPGPDSTAELIATLAEAEDNDVINADARVMLERVLRMAEMTAGDVLVPAPRMDM
LDIDAPVDELMHQVLHTAHSRFPVYQGERDNIIGILLAKDLLKLWRSPGLNVRTLVRPALFVPESKGLHDLGREFRNTRN
HMAIAIDEFGRIAGLVTFEDVIEQIVGEIEDEFDIPEDEGDIFGLADRTFRVSGDTPVERVAEAFGVALQGSDPDESFDT
IGGLIAHELGRMPRKGESVVLGGLQFVVMHTKGGSVRWFKVAPAAGTPESER

Sequences:

>Translated_292_residues
MSDPHPARASDKEDKRTFLQRLVEFINPGPDSTAELIATLAEAEDNDVINADARVMLERVLRMAEMTAGDVLVPAPRMDM
LDIDAPVDELMHQVLHTAHSRFPVYQGERDNIIGILLAKDLLKLWRSPGLNVRTLVRPALFVPESKGLHDLGREFRNTRN
HMAIAIDEFGRIAGLVTFEDVIEQIVGEIEDEFDIPEDEGDIFGLADRTFRVSGDTPVERVAEAFGVALQGSDPDESFDT
IGGLIAHELGRMPRKGESVVLGGLQFVVMHTKGGSVRWFKVAPAAGTPESER
>Mature_291_residues
SDPHPARASDKEDKRTFLQRLVEFINPGPDSTAELIATLAEAEDNDVINADARVMLERVLRMAEMTAGDVLVPAPRMDML
DIDAPVDELMHQVLHTAHSRFPVYQGERDNIIGILLAKDLLKLWRSPGLNVRTLVRPALFVPESKGLHDLGREFRNTRNH
MAIAIDEFGRIAGLVTFEDVIEQIVGEIEDEFDIPEDEGDIFGLADRTFRVSGDTPVERVAEAFGVALQGSDPDESFDTI
GGLIAHELGRMPRKGESVVLGGLQFVVMHTKGGSVRWFKVAPAAGTPESER

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=203, Percent_Identity=31.5270935960591, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI40068055, Length=167, Percent_Identity=29.940119760479, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI40068053, Length=167, Percent_Identity=29.940119760479, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI94681046, Length=167, Percent_Identity=30.5389221556886, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI40068049, Length=140, Percent_Identity=35, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1786879, Length=271, Percent_Identity=39.1143911439114, Blast_Score=164, Evalue=8e-42,
Organism=Escherichia coli, GI87082033, Length=260, Percent_Identity=29.2307692307692, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1788119, Length=217, Percent_Identity=33.1797235023041, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI145693175, Length=239, Percent_Identity=26.3598326359833, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1790664, Length=222, Percent_Identity=24.7747747747748, Blast_Score=75, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 32243; Mature: 32112

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDPHPARASDKEDKRTFLQRLVEFINPGPDSTAELIATLAEAEDNDVINADARVMLERV
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEECHHHHHHHHHH
LRMAEMTAGDVLVPAPRMDMLDIDAPVDELMHQVLHTAHSRFPVYQGERDNIIGILLAKD
HHHHHHCCCCEEECCCCCCCEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHH
LLKLWRSPGLNVRTLVRPALFVPESKGLHDLGREFRNTRNHMAIAIDEFGRIAGLVTFED
HHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHH
VIEQIVGEIEDEFDIPEDEGDIFGLADRTFRVSGDTPVERVAEAFGVALQGSDPDESFDT
HHHHHHHHHHHHCCCCCCCCCEEEECCCEEEECCCCHHHHHHHHHCEEECCCCCCHHHHH
IGGLIAHELGRMPRKGESVVLGGLQFVVMHTKGGSVRWFKVAPAAGTPESER
HHHHHHHHHHCCCCCCCEEEEECEEEEEEECCCCCEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
SDPHPARASDKEDKRTFLQRLVEFINPGPDSTAELIATLAEAEDNDVINADARVMLERV
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEECHHHHHHHHHH
LRMAEMTAGDVLVPAPRMDMLDIDAPVDELMHQVLHTAHSRFPVYQGERDNIIGILLAKD
HHHHHHCCCCEEECCCCCCCEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHH
LLKLWRSPGLNVRTLVRPALFVPESKGLHDLGREFRNTRNHMAIAIDEFGRIAGLVTFED
HHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHH
VIEQIVGEIEDEFDIPEDEGDIFGLADRTFRVSGDTPVERVAEAFGVALQGSDPDESFDT
HHHHHHHHHHHHCCCCCCCCCEEEECCCEEEECCCCHHHHHHHHHCEEECCCCCCHHHHH
IGGLIAHELGRMPRKGESVVLGGLQFVVMHTKGGSVRWFKVAPAAGTPESER
HHHHHHHHHHCCCCCCCEEEEECEEEEEEECCCCCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12522265 [H]