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The map label for this gene is htpG [H]

Identifier: 222109685

GI number: 222109685

Start: 480654

End: 482606

Strand: Direct

Name: htpG [H]

Synonym: Dtpsy_0466

Alternate gene names: 222109685

Gene position: 480654-482606 (Clockwise)

Preceding gene: 222109684

Following gene: 222109686

Centisome position: 12.66

GC content: 64.77

Gene sequence:

>1953_bases
ATGAGCAAGCACACCCATTCCTTCCAGGCCGAAGTGGCGCAACTGCTGCACCTGGTCACGCATTCGCTGTATTCCAACAA
AGAGATCTTCCTGCGCGAGCTGGTCTCTAACGCCTCGGACGCCTGTGACAAGCTGCGCTTTGAAGCGCTGAACAATGCCG
CGCTGTACGAGGATGCGCCCAACCTGGAGGTGCGCGTGTCCTTCGACAAGGAAGCGCGCACGCTGACCATCACCGATAAC
GGCATCGGCATGAGCGAGCAGGAGGCCATTGACCACCTGGGCACGATCGCCAAGAGCGGTACGCGCGACTTCATGAACCG
CCTGTCGGGCGACCAGAAGGCCGACGCGCAGCTGATCGGCCAGTTTGGCGTGGGCTTCTACTCGGGCTTCATCGTGGCCG
ATCGCATCACGGTCGAGAGCCGCCGCGCGGGCCTGCCCGCCAGCGAAGGCGTGCGCTGGGCCAGCGGCGGCGCGGGCGAC
TTCGAGGTGGAGGCCATCGAGCGTGCGGCGCGCGGCACCAGCGTGATCCTGCACCTGCGCGAGGATGCCGAGGAGTTCCT
CAACGCCTGGAAGATCAAGCAGGTGATCGGCAAGTATTCCGACCACATCAGCCTGCCCATCCTCATGGAGAAGGAGGAGT
GGAAAGAGAGCGAGAAGGAAGGCGAGCCGGGCCAGATGGTGAAGACCGGCGAGTGGGAAACCGTGAACAAGGCCAGCGCC
CTGTGGACGCGGCCCAAGAAGGACATCACCGACGAGCAGTACCAGGACTTCTACAAGTCCATCAGCCACGACTTCGAGAA
CCCGCTCACCTGGAGCCACAACCGCGTCGAGGGCAACACCGAGTACACGCAGTTGCTGTACATCCCCGCCAAGGCGCCGT
TCGACCTGTGGAACCGCGACAAGAAGGCCGGCGTGAAGCTGTACGTCAAGCGCGTGTTCATCATGGACGACGCCGAGTCG
CTCATGCCCAGCTACCTGCGCTTCGTCAAGGGCGTGATCGACTCCGCCGACCTGCCGCTGAACGTGAGCCGCGAGCTGCT
GCAGGAAAGCCGCGACGTGCGCCTGATCCGCGATGGCTCGGTCAAGCGCGTGCTGTCCATGCTCGAGGACCTGGCCAAGC
ACGACAAGCATGAGGCAGCGGCGGAAGGCGCCGATGGCGTGCAGGACGTGGTCAGCGCCGAGGACAAGGCCAAGGAAGGC
AAGTACACCCAGTTCTACGCCGAGTTCGGCGCCGTGCTCAAGGAAGGCCTGGGCGAGGACTTCGCCAACCGCGAACGTCT
GGCCAAGCTGCTGCGCTTTGCCTCCACCACATCGGATACGCCGAGCGTTTCCTTTGCCGACTACAAGGCGCGCATGAAGG
AGGGCCAGGAGGCCATCTACTACATCACCGCCGACACGCTGGCCGCCGCCAAGAACAGCCCGCAGCTCGAAGTCTTCAAG
AAGAAGGGCATCGAGGTGCTGCTCATGACCGACCGCGTGGACGAGTGGGCGCTGAACTACCTGCAGGACTTCGATGGCAC
GCCGCTGCAGTCCGTGGCCAAGGGCGCGGTGGACCTGGGCAAGCTGCAGGACGAGGCCGAGAAGAAGGCCGCCGAGGAGG
CCGCCGAGGCCTTCAAGCCCGTGCTCGCCAAGCTCAAGGAAGCGCTCAAGGACAAGGCCGAGGACGTGCGCGTGACCACG
CGCCTGGTTGATTCGCCCGCTTGCCTGGTGGTGCAGGACGGCGGCATGAGCACGCAGCTCGCGCGCCTGCTCAAGCAGGC
CGGCCAGAGCGCGCCTGACGCCAAGCCTGTGCTGGAAGTGAACCCCGAGCATGCGCTGGTCAAGAAGCTGGACGGCAGCG
TGCACTTTCACGACCTGGCGCACATCCTGTTCGACCAGGCGTTGCTGGCCGAAGGAGGCCTGCCCGAGGACCCGGCCGCG
TACGTGAAGCGCGTGAACGCGCTGCTGGCCTGA

Upstream 100 bases:

>100_bases
GTCGCGGCGCCCCCACCTGCGCATGCGTTCCGGCCGCGCCGGAGAACATGGTTGAATCCCCTGTGATTTCTTTCCCGTTG
CCTTTGTTTGAAAAACACCT

Downstream 100 bases:

>100_bases
GGCGGGCCTGCCACCCTCGCGCCCGGCCTGTGCCGGGCCGTCTCTACAGACCGACTACACCCGGTCCTGCGCAAGCAGGC
CGGGTTTTTTTGCGCCACGG

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 650; Mature: 649

Protein sequence:

>650_residues
MSKHTHSFQAEVAQLLHLVTHSLYSNKEIFLRELVSNASDACDKLRFEALNNAALYEDAPNLEVRVSFDKEARTLTITDN
GIGMSEQEAIDHLGTIAKSGTRDFMNRLSGDQKADAQLIGQFGVGFYSGFIVADRITVESRRAGLPASEGVRWASGGAGD
FEVEAIERAARGTSVILHLREDAEEFLNAWKIKQVIGKYSDHISLPILMEKEEWKESEKEGEPGQMVKTGEWETVNKASA
LWTRPKKDITDEQYQDFYKSISHDFENPLTWSHNRVEGNTEYTQLLYIPAKAPFDLWNRDKKAGVKLYVKRVFIMDDAES
LMPSYLRFVKGVIDSADLPLNVSRELLQESRDVRLIRDGSVKRVLSMLEDLAKHDKHEAAAEGADGVQDVVSAEDKAKEG
KYTQFYAEFGAVLKEGLGEDFANRERLAKLLRFASTTSDTPSVSFADYKARMKEGQEAIYYITADTLAAAKNSPQLEVFK
KKGIEVLLMTDRVDEWALNYLQDFDGTPLQSVAKGAVDLGKLQDEAEKKAAEEAAEAFKPVLAKLKEALKDKAEDVRVTT
RLVDSPACLVVQDGGMSTQLARLLKQAGQSAPDAKPVLEVNPEHALVKKLDGSVHFHDLAHILFDQALLAEGGLPEDPAA
YVKRVNALLA

Sequences:

>Translated_650_residues
MSKHTHSFQAEVAQLLHLVTHSLYSNKEIFLRELVSNASDACDKLRFEALNNAALYEDAPNLEVRVSFDKEARTLTITDN
GIGMSEQEAIDHLGTIAKSGTRDFMNRLSGDQKADAQLIGQFGVGFYSGFIVADRITVESRRAGLPASEGVRWASGGAGD
FEVEAIERAARGTSVILHLREDAEEFLNAWKIKQVIGKYSDHISLPILMEKEEWKESEKEGEPGQMVKTGEWETVNKASA
LWTRPKKDITDEQYQDFYKSISHDFENPLTWSHNRVEGNTEYTQLLYIPAKAPFDLWNRDKKAGVKLYVKRVFIMDDAES
LMPSYLRFVKGVIDSADLPLNVSRELLQESRDVRLIRDGSVKRVLSMLEDLAKHDKHEAAAEGADGVQDVVSAEDKAKEG
KYTQFYAEFGAVLKEGLGEDFANRERLAKLLRFASTTSDTPSVSFADYKARMKEGQEAIYYITADTLAAAKNSPQLEVFK
KKGIEVLLMTDRVDEWALNYLQDFDGTPLQSVAKGAVDLGKLQDEAEKKAAEEAAEAFKPVLAKLKEALKDKAEDVRVTT
RLVDSPACLVVQDGGMSTQLARLLKQAGQSAPDAKPVLEVNPEHALVKKLDGSVHFHDLAHILFDQALLAEGGLPEDPAA
YVKRVNALLA
>Mature_649_residues
SKHTHSFQAEVAQLLHLVTHSLYSNKEIFLRELVSNASDACDKLRFEALNNAALYEDAPNLEVRVSFDKEARTLTITDNG
IGMSEQEAIDHLGTIAKSGTRDFMNRLSGDQKADAQLIGQFGVGFYSGFIVADRITVESRRAGLPASEGVRWASGGAGDF
EVEAIERAARGTSVILHLREDAEEFLNAWKIKQVIGKYSDHISLPILMEKEEWKESEKEGEPGQMVKTGEWETVNKASAL
WTRPKKDITDEQYQDFYKSISHDFENPLTWSHNRVEGNTEYTQLLYIPAKAPFDLWNRDKKAGVKLYVKRVFIMDDAESL
MPSYLRFVKGVIDSADLPLNVSRELLQESRDVRLIRDGSVKRVLSMLEDLAKHDKHEAAAEGADGVQDVVSAEDKAKEGK
YTQFYAEFGAVLKEGLGEDFANRERLAKLLRFASTTSDTPSVSFADYKARMKEGQEAIYYITADTLAAAKNSPQLEVFKK
KGIEVLLMTDRVDEWALNYLQDFDGTPLQSVAKGAVDLGKLQDEAEKKAAEEAAEAFKPVLAKLKEALKDKAEDVRVTTR
LVDSPACLVVQDGGMSTQLARLLKQAGQSAPDAKPVLEVNPEHALVKKLDGSVHFHDLAHILFDQALLAEGGLPEDPAAY
VKRVNALLA

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI20149594, Length=706, Percent_Identity=38.9518413597734, Blast_Score=444, Evalue=1e-124,
Organism=Homo sapiens, GI4507677, Length=702, Percent_Identity=37.7492877492877, Blast_Score=419, Evalue=1e-117,
Organism=Homo sapiens, GI155722983, Length=666, Percent_Identity=34.984984984985, Blast_Score=378, Evalue=1e-104,
Organism=Homo sapiens, GI154146191, Length=216, Percent_Identity=47.2222222222222, Blast_Score=194, Evalue=3e-49,
Organism=Homo sapiens, GI153792590, Length=216, Percent_Identity=47.2222222222222, Blast_Score=193, Evalue=3e-49,
Organism=Escherichia coli, GI1786679, Length=653, Percent_Identity=56.2021439509954, Blast_Score=736, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=688, Percent_Identity=38.5174418604651, Blast_Score=464, Evalue=1e-131,
Organism=Caenorhabditis elegans, GI17542208, Length=693, Percent_Identity=37.6623376623377, Blast_Score=403, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI115535205, Length=672, Percent_Identity=32.1428571428571, Blast_Score=300, Evalue=2e-81,
Organism=Caenorhabditis elegans, GI115535167, Length=455, Percent_Identity=32.967032967033, Blast_Score=242, Evalue=4e-64,
Organism=Saccharomyces cerevisiae, GI6323840, Length=703, Percent_Identity=38.6913229018492, Blast_Score=461, Evalue=1e-130,
Organism=Saccharomyces cerevisiae, GI6325016, Length=709, Percent_Identity=37.9407616361072, Blast_Score=454, Evalue=1e-128,
Organism=Drosophila melanogaster, GI17647529, Length=704, Percent_Identity=38.6363636363636, Blast_Score=464, Evalue=1e-130,
Organism=Drosophila melanogaster, GI21357739, Length=698, Percent_Identity=36.676217765043, Blast_Score=410, Evalue=1e-114,
Organism=Drosophila melanogaster, GI24586016, Length=677, Percent_Identity=35.0073855243722, Blast_Score=365, Evalue=1e-101,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 72242; Mature: 72111

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKHTHSFQAEVAQLLHLVTHSLYSNKEIFLRELVSNASDACDKLRFEALNNAALYEDAP
CCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCC
NLEVRVSFDKEARTLTITDNGIGMSEQEAIDHLGTIAKSGTRDFMNRLSGDQKADAQLIG
CCEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHH
QFGVGFYSGFIVADRITVESRRAGLPASEGVRWASGGAGDFEVEAIERAARGTSVILHLR
HHHHHHHHCEEEEEEEEEHHHHCCCCHHCCCEECCCCCCCCHHHHHHHHHCCCEEEEEEH
EDAEEFLNAWKIKQVIGKYSDHISLPILMEKEEWKESEKEGEPGQMVKTGEWETVNKASA
HHHHHHHHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHCCCCCCCEEECCCCCCHHHHHH
LWTRPKKDITDEQYQDFYKSISHDFENPLTWSHNRVEGNTEYTQLLYIPAKAPFDLWNRD
HHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHCCC
KKAGVKLYVKRVFIMDDAESLMPSYLRFVKGVIDSADLPLNVSRELLQESRDVRLIRDGS
HHCCHHEEEEHHEEECCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCEEEEECCC
VKRVLSMLEDLAKHDKHEAAAEGADGVQDVVSAEDKAKEGKYTQFYAEFGAVLKEGLGED
HHHHHHHHHHHHHHCHHHHHHCCCCHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHCCCC
FANRERLAKLLRFASTTSDTPSVSFADYKARMKEGQEAIYYITADTLAAAKNSPQLEVFK
CCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCEEEEEEEHHHHHCCCCCCHHHHH
KKGIEVLLMTDRVDEWALNYLQDFDGTPLQSVAKGAVDLGKLQDEAEKKAAEEAAEAFKP
HCCCEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLAKLKEALKDKAEDVRVTTRLVDSPACLVVQDGGMSTQLARLLKQAGQSAPDAKPVLEV
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCEEE
NPEHALVKKLDGSVHFHDLAHILFDQALLAEGGLPEDPAAYVKRVNALLA
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SKHTHSFQAEVAQLLHLVTHSLYSNKEIFLRELVSNASDACDKLRFEALNNAALYEDAP
CCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCC
NLEVRVSFDKEARTLTITDNGIGMSEQEAIDHLGTIAKSGTRDFMNRLSGDQKADAQLIG
CCEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHH
QFGVGFYSGFIVADRITVESRRAGLPASEGVRWASGGAGDFEVEAIERAARGTSVILHLR
HHHHHHHHCEEEEEEEEEHHHHCCCCHHCCCEECCCCCCCCHHHHHHHHHCCCEEEEEEH
EDAEEFLNAWKIKQVIGKYSDHISLPILMEKEEWKESEKEGEPGQMVKTGEWETVNKASA
HHHHHHHHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHCCCCCCCEEECCCCCCHHHHHH
LWTRPKKDITDEQYQDFYKSISHDFENPLTWSHNRVEGNTEYTQLLYIPAKAPFDLWNRD
HHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHCCC
KKAGVKLYVKRVFIMDDAESLMPSYLRFVKGVIDSADLPLNVSRELLQESRDVRLIRDGS
HHCCHHEEEEHHEEECCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCEEEEECCC
VKRVLSMLEDLAKHDKHEAAAEGADGVQDVVSAEDKAKEGKYTQFYAEFGAVLKEGLGED
HHHHHHHHHHHHHHCHHHHHHCCCCHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHCCCC
FANRERLAKLLRFASTTSDTPSVSFADYKARMKEGQEAIYYITADTLAAAKNSPQLEVFK
CCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCEEEEEEEHHHHHCCCCCCHHHHH
KKGIEVLLMTDRVDEWALNYLQDFDGTPLQSVAKGAVDLGKLQDEAEKKAAEEAAEAFKP
HCCCEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLAKLKEALKDKAEDVRVTTRLVDSPACLVVQDGGMSTQLARLLKQAGQSAPDAKPVLEV
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCEEE
NPEHALVKKLDGSVHFHDLAHILFDQALLAEGGLPEDPAAYVKRVNALLA
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA