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The map label for this gene is gmhA [H]

Identifier: 222109627

GI number: 222109627

Start: 412744

End: 413337

Strand: Direct

Name: gmhA [H]

Synonym: Dtpsy_0407

Alternate gene names: 222109627

Gene position: 412744-413337 (Clockwise)

Preceding gene: 222109626

Following gene: 222109628

Centisome position: 10.87

GC content: 68.69

Gene sequence:

>594_bases
ATGCTTGAGCAACGCATCCAACAGCATTTCATCGACAGCGCCGACCTGAAATACCAGTCGGCCCAGGCGCTCAGCCATCC
CATCAGCGCAGCCGTGCAGGCCATCTGGGCCTGTGTGACCAACGGCGCCAAGGTGCTGGCCTGCGGTAGCGGCCCTTCGT
CCGCGCAGGCCCTGCAGTTCGCGGCCTTTTGCGTGGCCGGTTTCGAGCGCGATAGGCCCGAACTGGCGGCGCTGGCCCTG
GTGCCCGATGCCCTGGCCACCGGCACCAGCGCCGTAGCGGACAGCGCCGTGCTGGCGCGCCAGGTGCGCGCCCTGGGGCA
GGCAGGAGATCTGCTGCTGGTCATCACCATCGGCGGCAACGAGCCAGCCCTGCTGCAGGCCGTGCAGGCCGCCCATGAGC
GGGACATGACCGTGGTCGCCCTGTGTGGCCGCGACGGCGGGGCGTTGGGCGCGCTGCTGCACGAGACCGATGTCCAGATC
TGCGTGCCGCACGACCGAGCCGCCCGTGTGCGCGAGGTGCATGCGCTGGTGCTGCACTGCCTGTGCGACGGCGTGGACGC
CCAGTTACTTGGAGAACAGGAGATTCCTCTATGA

Upstream 100 bases:

>100_bases
GACCGGCTGCAGTGGCTGCGCGGCGCATTCGACGCCGCGTAGCGCGCGGCCTACCGTTTGCTACAGGCGCCGCGATACCC
GCAGGTATCATTCACGGCCC

Downstream 100 bases:

>100_bases
CATTTCCCCTGCTGCGAATTTCTAGCGCCGCGCTCGCGGCCGCGGCCCTGGCCGGCAGCCTCGCCGGCTGCGCGCCGCTG
GTCATCGGCGGCGGTGCCGT

Product: phosphoheptose isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase [H]

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MLEQRIQQHFIDSADLKYQSAQALSHPISAAVQAIWACVTNGAKVLACGSGPSSAQALQFAAFCVAGFERDRPELAALAL
VPDALATGTSAVADSAVLARQVRALGQAGDLLLVITIGGNEPALLQAVQAAHERDMTVVALCGRDGGALGALLHETDVQI
CVPHDRAARVREVHALVLHCLCDGVDAQLLGEQEIPL

Sequences:

>Translated_197_residues
MLEQRIQQHFIDSADLKYQSAQALSHPISAAVQAIWACVTNGAKVLACGSGPSSAQALQFAAFCVAGFERDRPELAALAL
VPDALATGTSAVADSAVLARQVRALGQAGDLLLVITIGGNEPALLQAVQAAHERDMTVVALCGRDGGALGALLHETDVQI
CVPHDRAARVREVHALVLHCLCDGVDAQLLGEQEIPL
>Mature_197_residues
MLEQRIQQHFIDSADLKYQSAQALSHPISAAVQAIWACVTNGAKVLACGSGPSSAQALQFAAFCVAGFERDRPELAALAL
VPDALATGTSAVADSAVLARQVRALGQAGDLLLVITIGGNEPALLQAVQAAHERDMTVVALCGRDGGALGALLHETDVQI
CVPHDRAARVREVHALVLHCLCDGVDAQLLGEQEIPL

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate [H]

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1789539, Length=197, Percent_Identity=43.1472081218274, Blast_Score=153, Evalue=9e-39,
Organism=Escherichia coli, GI1786416, Length=170, Percent_Identity=31.7647058823529, Blast_Score=92, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020620
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.28 [H]

Molecular weight: Translated: 20529; Mature: 20529

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEQRIQQHFIDSADLKYQSAQALSHPISAAVQAIWACVTNGAKVLACGSGPSSAQALQF
CCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHH
AAFCVAGFERDRPELAALALVPDALATGTSAVADSAVLARQVRALGQAGDLLLVITIGGN
HHHHHHCCCCCCCHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCC
EPALLQAVQAAHERDMTVVALCGRDGGALGALLHETDVQICVPHDRAARVREVHALVLHC
CHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHEECCCCEEEECCHHHHHHHHHHHHHHHH
LCDGVDAQLLGEQEIPL
HHCCCCHHHCCCCCCCC
>Mature Secondary Structure
MLEQRIQQHFIDSADLKYQSAQALSHPISAAVQAIWACVTNGAKVLACGSGPSSAQALQF
CCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHH
AAFCVAGFERDRPELAALALVPDALATGTSAVADSAVLARQVRALGQAGDLLLVITIGGN
HHHHHHCCCCCCCHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCC
EPALLQAVQAAHERDMTVVALCGRDGGALGALLHETDVQICVPHDRAARVREVHALVLHC
CHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHEECCCCEEEECCHHHHHHHHHHHHHHHH
LCDGVDAQLLGEQEIPL
HHCCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA