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The map label for this gene is gph [C]

Identifier: 222109572

GI number: 222109572

Start: 361121

End: 361846

Strand: Direct

Name: gph [C]

Synonym: Dtpsy_0352

Alternate gene names: 222109572

Gene position: 361121-361846 (Clockwise)

Preceding gene: 222109570

Following gene: 222109576

Centisome position: 9.51

GC content: 67.63

Gene sequence:

>726_bases
ATGGAACGGGTGCAACAAGACCTCGCCGCGCTGCTCGCGCGCACCGACGCCGCGATCGTGGACCTCGACGGCACCATGGT
GGATACGTTGGGCGATTTTGCCGAGGCGCTCAATCGCATGCTGCGCGACCTGCAGCTCCCCGCCATCGCGCCCGCGGCGA
TCGAACGCATGGTCGGCAAGGGGTCGGAGCATCTCCTGCGTTCAGTACTAAAACACGTTCTAGCGCCCGACCAGCAAGCG
CTGACAGCTATGCAATTGGAAGCAAAGGCCGAGGCCTTGTATCCCCAGGCGTGGGAGCGCTACCAGCACCATTACCTGGC
CATCAACGGCCAGTATGCGGCGCTGTACGCCGGCGTGGCCGAAGGGCTTGCGGCGCTGCACCGCACCGGTCGGCCGCTGG
TGTGCCTGACCAACAAGCCCACCGACTTCGCCCGGCCTCTGCTGCGCGCCAAAGGGCTGGACGGCTTCTTCACCCACGTG
TTCGGCGGCGATGCGTTCGCGCGCAAGAAGCCCGACCCGCTGCCACTGCTCAAGGCCTGCGAGGCGGTGGGAACCTCGCC
GGCGCGCACGCTGATGATCGGCGACTCCAGCAACGATGCCCAGGCCGCGCGTGCGGCGGGCTGCCCCGTGGTGCTGGTGA
CGTACGGCTACAACCACGGCCAGCCCGTGCGCGGCGTGGACGCGGACGGCTACGTGGATGCGCTCACCGAGCTGATCGCT
AGCTGA

Upstream 100 bases:

>100_bases
CCCGGAAGGCGTCTGTCCGCATGCGGCGCCGTGGTGTGTCGGACGGGTCGGACAGCGCATACACTGCCCGCGCTCAATGC
ATGACTGACAAGGACAAGGG

Downstream 100 bases:

>100_bases
ATTCCTCCGGCCGCATGCGCGCCATGGGCGCCGCGCGGGGCGCCCGGGTCCTCAGAAGCTCTCCCACTCGTCGTTATCGG
CAGCCGTGCGGGCCGCTTGC

Product: phosphoglycolate phosphatase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MERVQQDLAALLARTDAAIVDLDGTMVDTLGDFAEALNRMLRDLQLPAIAPAAIERMVGKGSEHLLRSVLKHVLAPDQQA
LTAMQLEAKAEALYPQAWERYQHHYLAINGQYAALYAGVAEGLAALHRTGRPLVCLTNKPTDFARPLLRAKGLDGFFTHV
FGGDAFARKKPDPLPLLKACEAVGTSPARTLMIGDSSNDAQAARAAGCPVVLVTYGYNHGQPVRGVDADGYVDALTELIA
S

Sequences:

>Translated_241_residues
MERVQQDLAALLARTDAAIVDLDGTMVDTLGDFAEALNRMLRDLQLPAIAPAAIERMVGKGSEHLLRSVLKHVLAPDQQA
LTAMQLEAKAEALYPQAWERYQHHYLAINGQYAALYAGVAEGLAALHRTGRPLVCLTNKPTDFARPLLRAKGLDGFFTHV
FGGDAFARKKPDPLPLLKACEAVGTSPARTLMIGDSSNDAQAARAAGCPVVLVTYGYNHGQPVRGVDADGYVDALTELIA
S
>Mature_241_residues
MERVQQDLAALLARTDAAIVDLDGTMVDTLGDFAEALNRMLRDLQLPAIAPAAIERMVGKGSEHLLRSVLKHVLAPDQQA
LTAMQLEAKAEALYPQAWERYQHHYLAINGQYAALYAGVAEGLAALHRTGRPLVCLTNKPTDFARPLLRAKGLDGFFTHV
FGGDAFARKKPDPLPLLKACEAVGTSPARTLMIGDSSNDAQAARAAGCPVVLVTYGYNHGQPVRGVDADGYVDALTELIA
S

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=227, Percent_Identity=35.2422907488987, Blast_Score=126, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR000150
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 25857; Mature: 25857

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERVQQDLAALLARTDAAIVDLDGTMVDTLGDFAEALNRMLRDLQLPAIAPAAIERMVGK
CHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCC
GSEHLLRSVLKHVLAPDQQALTAMQLEAKAEALYPQAWERYQHHYLAINGQYAALYAGVA
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHCCEEEEECCCHHHHHHHHH
EGLAALHRTGRPLVCLTNKPTDFARPLLRAKGLDGFFTHVFGGDAFARKKPDPLPLLKAC
HHHHHHHHCCCCEEEECCCCCHHHHHHHHHCCCCHHHHHHHCCCHHHCCCCCCCHHHHHH
EAVGTSPARTLMIGDSSNDAQAARAAGCPVVLVTYGYNHGQPVRGVDADGYVDALTELIA
HHHCCCCCEEEEEECCCCHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHC
S
C
>Mature Secondary Structure
MERVQQDLAALLARTDAAIVDLDGTMVDTLGDFAEALNRMLRDLQLPAIAPAAIERMVGK
CHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCC
GSEHLLRSVLKHVLAPDQQALTAMQLEAKAEALYPQAWERYQHHYLAINGQYAALYAGVA
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHCCEEEEECCCHHHHHHHHH
EGLAALHRTGRPLVCLTNKPTDFARPLLRAKGLDGFFTHVFGGDAFARKKPDPLPLLKAC
HHHHHHHHCCCCEEEECCCCCHHHHHHHHHCCCCHHHHHHHCCCHHHCCCCCCCHHHHHH
EAVGTSPARTLMIGDSSNDAQAARAAGCPVVLVTYGYNHGQPVRGVDADGYVDALTELIA
HHHCCCCCEEEEEECCCCHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHC
S
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA