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The map label for this gene is rpe [H]

Identifier: 222109570

GI number: 222109570

Start: 359869

End: 360549

Strand: Direct

Name: rpe [H]

Synonym: Dtpsy_0350

Alternate gene names: 222109570

Gene position: 359869-360549 (Clockwise)

Preceding gene: 222109562

Following gene: 222109572

Centisome position: 9.48

GC content: 65.64

Gene sequence:

>681_bases
ATGAGCCGCACCTACCGCATCGCCCCCTCCATCCTGTCTGCCGACTTTGCCCGCCTGGGTGAGGAAGTGCGCAACGTCAT
CGCCGCCGGCGCCGACTGGATCCACTTTGACGTGATGGACAACCACTATGTGCCCAACCTCACCTTCGGCCCGATGGTGT
GCCAGGCCCTCAAGCCCCATGCCGTGACGCCCGCAGGGCACGCCGTACCGATCGACGTGCACTTGATGGTGCAGCCCGTG
GACGAACTGGCCACGGCGTTTGCCAAGGCGGGGGCGGACCTCATCAGCTTCCACCCCGATGCCTCGGCGCACGTGCACCG
CAGCATTCAGAACATCCGCGCGCAGGGCTGCAAGGCAGGCCTGACCTTCAACCCCGCCATGCCGCTTGACGTGCTGGACT
GGGTGATCGAGGACATCGACCTGATCCTGTTGATGAGCGTGAACCCCGGCTTTGGCGGACAGAGCTTCATCGACAGCACG
CTGCGCAAGATCGAAGCGGCCCGCAGGCGCATCGAGGCCTCGGGCAAGGACATCCGCCTGGAGGTGGACGGTGGCATCAA
GGCCGACAACATCCGCCGGGTGGCGGATGCGGGCGCGGACACGTTCGTTGCAGGCAGCGCCATCTTCGGCAAGAGCGACT
ACAAGGCGGTGATCGACGCCATGCGCGCCGAACTGGCGTGA

Upstream 100 bases:

>100_bases
GTGCGGCCCGCGTCGCACAAGGCCTGCTAAGGCCCCGCTCCGGCTGTGCCCGGCATGCGAACGTCGCGCCGCGGCGGCGT
CAACTGCGACAATCGCGGCC

Downstream 100 bases:

>100_bases
GGCGCCGCCGCGCGGCTTGATCGCAATCCGCTGAAAAGCCTATTGCACCGGCGTGGTGGCTTCGCGCAGCACGCCACCGC
CTTCCACCGAGCCTGACACC

Product: ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MSRTYRIAPSILSADFARLGEEVRNVIAAGADWIHFDVMDNHYVPNLTFGPMVCQALKPHAVTPAGHAVPIDVHLMVQPV
DELATAFAKAGADLISFHPDASAHVHRSIQNIRAQGCKAGLTFNPAMPLDVLDWVIEDIDLILLMSVNPGFGGQSFIDST
LRKIEAARRRIEASGKDIRLEVDGGIKADNIRRVADAGADTFVAGSAIFGKSDYKAVIDAMRAELA

Sequences:

>Translated_226_residues
MSRTYRIAPSILSADFARLGEEVRNVIAAGADWIHFDVMDNHYVPNLTFGPMVCQALKPHAVTPAGHAVPIDVHLMVQPV
DELATAFAKAGADLISFHPDASAHVHRSIQNIRAQGCKAGLTFNPAMPLDVLDWVIEDIDLILLMSVNPGFGGQSFIDST
LRKIEAARRRIEASGKDIRLEVDGGIKADNIRRVADAGADTFVAGSAIFGKSDYKAVIDAMRAELA
>Mature_225_residues
SRTYRIAPSILSADFARLGEEVRNVIAAGADWIHFDVMDNHYVPNLTFGPMVCQALKPHAVTPAGHAVPIDVHLMVQPVD
ELATAFAKAGADLISFHPDASAHVHRSIQNIRAQGCKAGLTFNPAMPLDVLDWVIEDIDLILLMSVNPGFGGQSFIDSTL
RKIEAARRRIEASGKDIRLEVDGGIKADNIRRVADAGADTFVAGSAIFGKSDYKAVIDAMRAELA

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=222, Percent_Identity=36.9369369369369, Blast_Score=156, Evalue=1e-38,
Organism=Homo sapiens, GI219879828, Length=222, Percent_Identity=35.1351351351351, Blast_Score=147, Evalue=8e-36,
Organism=Homo sapiens, GI24307923, Length=168, Percent_Identity=30.952380952381, Blast_Score=91, Evalue=8e-19,
Organism=Escherichia coli, GI1789788, Length=224, Percent_Identity=64.7321428571429, Blast_Score=299, Evalue=1e-82,
Organism=Escherichia coli, GI1790523, Length=203, Percent_Identity=34.9753694581281, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1790754, Length=215, Percent_Identity=28.8372093023256, Blast_Score=91, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17552948, Length=219, Percent_Identity=37.8995433789954, Blast_Score=151, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6322341, Length=227, Percent_Identity=37.4449339207048, Blast_Score=160, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24586301, Length=217, Percent_Identity=35.4838709677419, Blast_Score=142, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 24384; Mature: 24253

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1 ; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRTYRIAPSILSADFARLGEEVRNVIAAGADWIHFDVMDNHYVPNLTFGPMVCQALKPH
CCCCEECCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCC
AVTPAGHAVPIDVHLMVQPVDELATAFAKAGADLISFHPDASAHVHRSIQNIRAQGCKAG
CCCCCCCEEEEEEEEEECCHHHHHHHHHHCCCHHEEECCCCHHHHHHHHHHHHHHCCCCC
LTFNPAMPLDVLDWVIEDIDLILLMSVNPGFGGQSFIDSTLRKIEAARRRIEASGKDIRL
CEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEE
EVDGGIKADNIRRVADAGADTFVAGSAIFGKSDYKAVIDAMRAELA
EECCCCCHHHHHHHHHCCCCCEEECCHHCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SRTYRIAPSILSADFARLGEEVRNVIAAGADWIHFDVMDNHYVPNLTFGPMVCQALKPH
CCCEECCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCC
AVTPAGHAVPIDVHLMVQPVDELATAFAKAGADLISFHPDASAHVHRSIQNIRAQGCKAG
CCCCCCCEEEEEEEEEECCHHHHHHHHHHCCCHHEEECCCCHHHHHHHHHHHHHHCCCCC
LTFNPAMPLDVLDWVIEDIDLILLMSVNPGFGGQSFIDSTLRKIEAARRRIEASGKDIRL
CEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEE
EVDGGIKADNIRRVADAGADTFVAGSAIFGKSDYKAVIDAMRAELA
EECCCCCHHHHHHHHHCCCCCEEECCHHCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]