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The map label for this gene is murA [H]

Identifier: 222109561

GI number: 222109561

Start: 349841

End: 351142

Strand: Direct

Name: murA [H]

Synonym: Dtpsy_0341

Alternate gene names: 222109561

Gene position: 349841-351142 (Clockwise)

Preceding gene: 222109560

Following gene: 222109562

Centisome position: 9.21

GC content: 68.82

Gene sequence:

>1302_bases
ATGTCCAACCTGATCGTGCATGGCGGCACGCCGCTGCGTGGCCGCGTCACCCCCTCTGCCAACAAGAACGCGGTATTGCC
CGTGCTGTGCGCCACGCTGCTCACGCGCGCGCCGCTGCGCCTGGTGGGCGTGCCCGACATCACCGACGTGCGCAAGATCC
TGGAGATCTTCCGCACCCTGGGCAGCGAGGTGCGCTGGGACCATGCCAGCGCCACGCTGGAACTGCACCACCAGGCCACG
CACTTCGACGCCGCCACGCACCGCCTGCCCGAGGAGATGCGCTCGTCCATCATGCTGGTGCCGCCGCTGCTGGCGCGCTT
CGGCGTGGCGCGGCTGGAGGACAACGTGAAGGGCTGCACCCTGGGCGTGCGCGAGATCGACCCGCATGTGGAGGTCTTTC
GCAGCTTCGGCGGCCAGGTGGAGCGGGCCGAGGGCTCGCTGCTGGTGCGCCGCGTGGGCATGCTCACGCCGGTGCACCAC
TGGCTGGACTATGCCTCGGTGACCACCACCGAGAACTTCGTGCTGTGCGCCGTGGCCGCGCAGGGCACCTCCACGCTGAC
CAACGCAGCGTCCGAGCCGCACGTGCAGGAGTTCTGCCGCTTCATGCAAATGCTGGGCGCGCAGATCGAGGGCGTGGGCA
CCTCGCGGCTTACGGTGCACGGCGGCGGCGACCTGGGGGGCGGTGAATTCCGCTTTGCCGAGGACTTTCACGAGATCACT
ACCTTCCTGGCGCTGGGGGCCATCACCGGCGGCGACGTGGTGGTGAAGAACAGCGCACCGGAGAACTTCCCGCTGATCGA
CCGTACGTTTGCCAAGTTTGGCGTGCGCGTGGAGCACCGGGACGGCTGGTCGCGCGCCTTCGTGGACGGGCCGCTCACGG
TGCAGACGCCCTTCACCCCCAACGTGCTGACCAAGGTGGAGGCCGCGCCCTGGCCCTATTTCCCGGTGGATCTGCTGCCG
ATCTTCATCGCGCTGGGCGTGCGCGCGCAGGGCAACGCCATGTTCTGGAACAAGGTGTACGACGGCGCTTTAGGCTGGAC
GGGCGAGCTGTCCAAGTTTGGCGCGCATGTGTACCAGTCCGACCCGCACCGCATCGTCACCTTCGGTGGCGGGCCGCTCG
CGCCGGCGGTGGTGGAGAGCCCCTACATCATCCGCGTGGCGATCGCGCTGTTCATGGTGGCGGCCAGTATCCCGGGGCGC
TCGGAGATCCGCAACGCCACGCCTATCCGCCGCGCGCACCCGCACTTTGTGGAGAACCTGCGCAGCCTGGGGGCCCGGGT
GGAGTGGACGGCAGAGGAGTAG

Upstream 100 bases:

>100_bases
TTGTGTCCAAGGACAAGGCTGTGCTTTGCATGCGAAAACGGCTGTTGACGCAGGACACGCATGCGGTGGCAGCTATTGTT
TTTGAAGAGGTTTGCGAACC

Downstream 100 bases:

>100_bases
CCGCGCCCTGATCGCCCCAGCCTTCGCTGCGCTGCAGCACAAAAGGGGATTGTGGTTTATACTTACGCCTAAGGGTTAAC
ACTTAGTGGTTAACCCGGTG

Product: epsp synthase (3-phosphoshikimate 1-carboxyvinyltransferase)

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 433; Mature: 432

Protein sequence:

>433_residues
MSNLIVHGGTPLRGRVTPSANKNAVLPVLCATLLTRAPLRLVGVPDITDVRKILEIFRTLGSEVRWDHASATLELHHQAT
HFDAATHRLPEEMRSSIMLVPPLLARFGVARLEDNVKGCTLGVREIDPHVEVFRSFGGQVERAEGSLLVRRVGMLTPVHH
WLDYASVTTTENFVLCAVAAQGTSTLTNAASEPHVQEFCRFMQMLGAQIEGVGTSRLTVHGGGDLGGGEFRFAEDFHEIT
TFLALGAITGGDVVVKNSAPENFPLIDRTFAKFGVRVEHRDGWSRAFVDGPLTVQTPFTPNVLTKVEAAPWPYFPVDLLP
IFIALGVRAQGNAMFWNKVYDGALGWTGELSKFGAHVYQSDPHRIVTFGGGPLAPAVVESPYIIRVAIALFMVAASIPGR
SEIRNATPIRRAHPHFVENLRSLGARVEWTAEE

Sequences:

>Translated_433_residues
MSNLIVHGGTPLRGRVTPSANKNAVLPVLCATLLTRAPLRLVGVPDITDVRKILEIFRTLGSEVRWDHASATLELHHQAT
HFDAATHRLPEEMRSSIMLVPPLLARFGVARLEDNVKGCTLGVREIDPHVEVFRSFGGQVERAEGSLLVRRVGMLTPVHH
WLDYASVTTTENFVLCAVAAQGTSTLTNAASEPHVQEFCRFMQMLGAQIEGVGTSRLTVHGGGDLGGGEFRFAEDFHEIT
TFLALGAITGGDVVVKNSAPENFPLIDRTFAKFGVRVEHRDGWSRAFVDGPLTVQTPFTPNVLTKVEAAPWPYFPVDLLP
IFIALGVRAQGNAMFWNKVYDGALGWTGELSKFGAHVYQSDPHRIVTFGGGPLAPAVVESPYIIRVAIALFMVAASIPGR
SEIRNATPIRRAHPHFVENLRSLGARVEWTAEE
>Mature_432_residues
SNLIVHGGTPLRGRVTPSANKNAVLPVLCATLLTRAPLRLVGVPDITDVRKILEIFRTLGSEVRWDHASATLELHHQATH
FDAATHRLPEEMRSSIMLVPPLLARFGVARLEDNVKGCTLGVREIDPHVEVFRSFGGQVERAEGSLLVRRVGMLTPVHHW
LDYASVTTTENFVLCAVAAQGTSTLTNAASEPHVQEFCRFMQMLGAQIEGVGTSRLTVHGGGDLGGGEFRFAEDFHEITT
FLALGAITGGDVVVKNSAPENFPLIDRTFAKFGVRVEHRDGWSRAFVDGPLTVQTPFTPNVLTKVEAAPWPYFPVDLLPI
FIALGVRAQGNAMFWNKVYDGALGWTGELSKFGAHVYQSDPHRIVTFGGGPLAPAVVESPYIIRVAIALFMVAASIPGRS
EIRNATPIRRAHPHFVENLRSLGARVEWTAEE

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=433, Percent_Identity=30.0230946882217, Blast_Score=191, Evalue=1e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 47311; Mature: 47180

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNLIVHGGTPLRGRVTPSANKNAVLPVLCATLLTRAPLRLVGVPDITDVRKILEIFRTL
CCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHH
GSEVRWDHASATLELHHQATHFDAATHRLPEEMRSSIMLVPPLLARFGVARLEDNVKGCT
CCCCEECCCCEEEEEEHHHHHHHHHHHHCCHHHHCCEEECCHHHHHHHHHHHHCCCCEEE
LGVREIDPHVEVFRSFGGQVERAEGSLLVRRVGMLTPVHHWLDYASVTTTENFVLCAVAA
EEHHHCCHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEEEC
QGTSTLTNAASEPHVQEFCRFMQMLGAQIEGVGTSRLTVHGGGDLGGGEFRFAEDFHEIT
CCCHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHH
TFLALGAITGGDVVVKNSAPENFPLIDRTFAKFGVRVEHRDGWSRAFVDGPLTVQTPFTP
HHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHCCEEEECCCCCEEEECCCEEEECCCCC
NVLTKVEAAPWPYFPVDLLPIFIALGVRAQGNAMFWNKVYDGALGWTGELSKFGAHVYQS
HHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEHHHHCCCCCCCCCHHHHHHHHCCC
DPHRIVTFGGGPLAPAVVESPYIIRVAIALFMVAASIPGRSEIRNATPIRRAHPHFVENL
CCCEEEEECCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCHHHHHHH
RSLGARVEWTAEE
HHCCCEEEEECCC
>Mature Secondary Structure 
SNLIVHGGTPLRGRVTPSANKNAVLPVLCATLLTRAPLRLVGVPDITDVRKILEIFRTL
CCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHH
GSEVRWDHASATLELHHQATHFDAATHRLPEEMRSSIMLVPPLLARFGVARLEDNVKGCT
CCCCEECCCCEEEEEEHHHHHHHHHHHHCCHHHHCCEEECCHHHHHHHHHHHHCCCCEEE
LGVREIDPHVEVFRSFGGQVERAEGSLLVRRVGMLTPVHHWLDYASVTTTENFVLCAVAA
EEHHHCCHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEEEC
QGTSTLTNAASEPHVQEFCRFMQMLGAQIEGVGTSRLTVHGGGDLGGGEFRFAEDFHEIT
CCCHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHH
TFLALGAITGGDVVVKNSAPENFPLIDRTFAKFGVRVEHRDGWSRAFVDGPLTVQTPFTP
HHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHCCEEEECCCCCEEEECCCEEEECCCCC
NVLTKVEAAPWPYFPVDLLPIFIALGVRAQGNAMFWNKVYDGALGWTGELSKFGAHVYQS
HHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEHHHHCCCCCCCCCHHHHHHHHCCC
DPHRIVTFGGGPLAPAVVESPYIIRVAIALFMVAASIPGRSEIRNATPIRRAHPHFVENL
CCCEEEEECCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCHHHHHHH
RSLGARVEWTAEE
HHCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9403685 [H]