Click here to switch to the map view.

The map label for this gene is aspC [H]

Identifier: 222109335

GI number: 222109335

Start: 127879

End: 129087

Strand: Direct

Name: aspC [H]

Synonym: Dtpsy_0113

Alternate gene names: 222109335

Gene position: 127879-129087 (Clockwise)

Preceding gene: 222109334

Following gene: 222109336

Centisome position: 3.37

GC content: 68.32

Gene sequence:

>1209_bases
ATGCACAACCCCGCTTCGCCCACCGATACCCTCCTGCCCGCCCTGGCGCGGCCCGCCATCCAGAGCCTGGGCGGATCGCT
GATCCGCGAAGTCGCCAACACCGGCATGGGGCGCGCGGACGTGCTGCCCTTCTGGTTTGGCGAGTCCGATCAGCCCACGC
CGCAGTTCATCCGGGATGCGGCGGCGCAGTCGCTCGGTTCGGGCGAGACCTTCTATTCGCAGAATCTGGGCCGGCCCTAC
CTGCGCGAGGCCATCGCGCAATATCTGTCGGACCTGCACGGACGCGAGGTGTCCGCCCAGCGCATCGGCGCTGTGGCCTC
GGGCGATGCCGGGCTGATGCTTACCTGCCAGATGCTGCTGTCGCCGGGCGACCGCGTGGTGGCCGTCACGCCGCTGTGGC
CCAACCTGCTGGAGATGCCGCGCATTCTGGGCGCGCAGGTTGAACGCGTGCCACTGGCGGTGCGGGGCGGGCGCTGGACG
CTTGCGCTGGATCGGCTGCTGGATGCGCTCACGCCGGGCACGCGCATGCTCATCCTCAATTCACCCAACAACCCCACAGG
CTGGACCATCGATGAGGAAAGCCTGGTGGCGATCCTCGCGCACTGCCGCCGCCATGGCATCTGGATTCTGAGCGACGACG
TGTACGAGCGTCTGGTATACGACCCGCAGCTGGCCAGCGCACCTTCTTTCCTGCGCCACTACGCACCGGGCGACCGCATC
ATCTCGGTCAACAGTTGTTCCAAGGCGTGGTGCATGACGGGTTGGCGCGCGGGTTGGATGGTGGTGCCCGAGGCGCTGGA
GGCCGACCTGGGCAAGGTCATTGAATACAACTTCTCGTGCATCTTCGAGCCCGTGCAGCGCGCCGCAACGGTGGCTTTAC
AGCAGGGCGAGGCGCATGTGGCGCAGCTGCGCGCGGGCCTCGTGGAAAGCCGCCGGCTGCTGGTGCAAGCGCTGCGTGCC
GTGCCGGGTGTGGAAGTGCCCGATGCCGGCGGGGCGATGTACGTGTTCTTCCGCCTGGCGGGCTTTGACGACTCCCTGGC
GCTTGCCAAACATCTGGTGAGCGAGGTCGGCTTGGGCCTGGCGCCGGGCGCGGCCTTCGGCCCCGAGGGTGAAGGCTGGC
TGCGCTGGTGCCACGCGGTGTCCGACGGGGCCAGACTGCGTGAGGGCGTGGAGCGTCTTGCGCGATTCGTGCAGCGTGCC
ACGGCTTGA

Upstream 100 bases:

>100_bases
ACTTCGCGCGGCGGCCTCGCGGTGAACATCGTGGAGTGCTGACGCGGTACGACCCTTAGCGCCCTGTTTCCCATACCTTT
TCGCTTTCCATCTGGCCCGC

Downstream 100 bases:

>100_bases
CAGGCGTGTGCGGCCGGCGGCCGCAGTCACCACGTGTACACGCGTCCCCGCCGTCCTTTCAACCTGCCTAAGCATGGGTT
GCTGAATCACGAAGCGTGTC

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MHNPASPTDTLLPALARPAIQSLGGSLIREVANTGMGRADVLPFWFGESDQPTPQFIRDAAAQSLGSGETFYSQNLGRPY
LREAIAQYLSDLHGREVSAQRIGAVASGDAGLMLTCQMLLSPGDRVVAVTPLWPNLLEMPRILGAQVERVPLAVRGGRWT
LALDRLLDALTPGTRMLILNSPNNPTGWTIDEESLVAILAHCRRHGIWILSDDVYERLVYDPQLASAPSFLRHYAPGDRI
ISVNSCSKAWCMTGWRAGWMVVPEALEADLGKVIEYNFSCIFEPVQRAATVALQQGEAHVAQLRAGLVESRRLLVQALRA
VPGVEVPDAGGAMYVFFRLAGFDDSLALAKHLVSEVGLGLAPGAAFGPEGEGWLRWCHAVSDGARLREGVERLARFVQRA
TA

Sequences:

>Translated_402_residues
MHNPASPTDTLLPALARPAIQSLGGSLIREVANTGMGRADVLPFWFGESDQPTPQFIRDAAAQSLGSGETFYSQNLGRPY
LREAIAQYLSDLHGREVSAQRIGAVASGDAGLMLTCQMLLSPGDRVVAVTPLWPNLLEMPRILGAQVERVPLAVRGGRWT
LALDRLLDALTPGTRMLILNSPNNPTGWTIDEESLVAILAHCRRHGIWILSDDVYERLVYDPQLASAPSFLRHYAPGDRI
ISVNSCSKAWCMTGWRAGWMVVPEALEADLGKVIEYNFSCIFEPVQRAATVALQQGEAHVAQLRAGLVESRRLLVQALRA
VPGVEVPDAGGAMYVFFRLAGFDDSLALAKHLVSEVGLGLAPGAAFGPEGEGWLRWCHAVSDGARLREGVERLARFVQRA
TA
>Mature_402_residues
MHNPASPTDTLLPALARPAIQSLGGSLIREVANTGMGRADVLPFWFGESDQPTPQFIRDAAAQSLGSGETFYSQNLGRPY
LREAIAQYLSDLHGREVSAQRIGAVASGDAGLMLTCQMLLSPGDRVVAVTPLWPNLLEMPRILGAQVERVPLAVRGGRWT
LALDRLLDALTPGTRMLILNSPNNPTGWTIDEESLVAILAHCRRHGIWILSDDVYERLVYDPQLASAPSFLRHYAPGDRI
ISVNSCSKAWCMTGWRAGWMVVPEALEADLGKVIEYNFSCIFEPVQRAATVALQQGEAHVAQLRAGLVESRRLLVQALRA
VPGVEVPDAGGAMYVFFRLAGFDDSLALAKHLVSEVGLGLAPGAAFGPEGEGWLRWCHAVSDGARLREGVERLARFVQRA
TA

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=401, Percent_Identity=24.6882793017456, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI169881279, Length=401, Percent_Identity=24.6882793017456, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI56713256, Length=397, Percent_Identity=25.9445843828715, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI56713254, Length=397, Percent_Identity=25.9445843828715, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI169881281, Length=272, Percent_Identity=23.8970588235294, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI4507369, Length=374, Percent_Identity=24.331550802139, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1788722, Length=359, Percent_Identity=30.08356545961, Blast_Score=134, Evalue=8e-33,
Organism=Escherichia coli, GI1786816, Length=352, Percent_Identity=26.1363636363636, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1788627, Length=339, Percent_Identity=28.023598820059, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1787909, Length=378, Percent_Identity=26.1904761904762, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787710, Length=362, Percent_Identity=26.2430939226519, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790797, Length=331, Percent_Identity=25.3776435045317, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788332, Length=248, Percent_Identity=28.6290322580645, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17567369, Length=322, Percent_Identity=26.0869565217391, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71994476, Length=383, Percent_Identity=24.8041775456919, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI71994472, Length=383, Percent_Identity=24.8041775456919, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17567663, Length=299, Percent_Identity=23.4113712374582, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322401, Length=255, Percent_Identity=28.2352941176471, Blast_Score=107, Evalue=2e-24,
Organism=Drosophila melanogaster, GI28573069, Length=387, Percent_Identity=25.8397932816537, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24646114, Length=387, Percent_Identity=25.8397932816537, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28573067, Length=387, Percent_Identity=25.8397932816537, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28573065, Length=387, Percent_Identity=25.8397932816537, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI18859735, Length=361, Percent_Identity=25.4847645429363, Blast_Score=92, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43620; Mature: 43620

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHNPASPTDTLLPALARPAIQSLGGSLIREVANTGMGRADVLPFWFGESDQPTPQFIRDA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCHHHHHHH
AAQSLGSGETFYSQNLGRPYLREAIAQYLSDLHGREVSAQRIGAVASGDAGLMLTCQMLL
HHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCHHHHHHHHH
SPGDRVVAVTPLWPNLLEMPRILGAQVERVPLAVRGGRWTLALDRLLDALTPGTRMLILN
CCCCCEEEECCCCHHHHHHHHHHHCHHHHCCEEEECCCHHHHHHHHHHHHCCCCEEEEEE
SPNNPTGWTIDEESLVAILAHCRRHGIWILSDDVYERLVYDPQLASAPSFLRHYAPGDRI
CCCCCCCCEECHHHHHHHHHHHHHCCEEEEEHHHHHHHHCCCCCCCCHHHHHHCCCCCCE
ISVNSCSKAWCMTGWRAGWMVVPEALEADLGKVIEYNFSCIFEPVQRAATVALQQGEAHV
EEECCCCHHHHHCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
AQLRAGLVESRRLLVQALRAVPGVEVPDAGGAMYVFFRLAGFDDSLALAKHLVSEVGLGL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCC
APGAAFGPEGEGWLRWCHAVSDGARLREGVERLARFVQRATA
CCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHNPASPTDTLLPALARPAIQSLGGSLIREVANTGMGRADVLPFWFGESDQPTPQFIRDA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCHHHHHHH
AAQSLGSGETFYSQNLGRPYLREAIAQYLSDLHGREVSAQRIGAVASGDAGLMLTCQMLL
HHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCHHHHHHHHH
SPGDRVVAVTPLWPNLLEMPRILGAQVERVPLAVRGGRWTLALDRLLDALTPGTRMLILN
CCCCCEEEECCCCHHHHHHHHHHHCHHHHCCEEEECCCHHHHHHHHHHHHCCCCEEEEEE
SPNNPTGWTIDEESLVAILAHCRRHGIWILSDDVYERLVYDPQLASAPSFLRHYAPGDRI
CCCCCCCCEECHHHHHHHHHHHHHCCEEEEEHHHHHHHHCCCCCCCCHHHHHHCCCCCCE
ISVNSCSKAWCMTGWRAGWMVVPEALEADLGKVIEYNFSCIFEPVQRAATVALQQGEAHV
EEECCCCHHHHHCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
AQLRAGLVESRRLLVQALRAVPGVEVPDAGGAMYVFFRLAGFDDSLALAKHLVSEVGLGL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCC
APGAAFGPEGEGWLRWCHAVSDGARLREGVERLARFVQRATA
CCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]