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The map label for this gene is recQ [H]

Identifier: 222109326

GI number: 222109326

Start: 111704

End: 113575

Strand: Direct

Name: recQ [H]

Synonym: Dtpsy_0103

Alternate gene names: 222109326

Gene position: 111704-113575 (Clockwise)

Preceding gene: 222109319

Following gene: 222109332

Centisome position: 2.94

GC content: 70.41

Gene sequence:

>1872_bases
TTGTCCCCCGCGCATTTCGTCCTGCACGACGTCTTTGGCTACGAGCAGTTCCGTGGCCCGCAGCAGGCCATCATCGACCA
TGTGATCGCCGGCGGCGACGCGCTGGTGCTGATGCCCACGGGCGGCGGCAAGAGCCTGTGCTACCAGGTGCCGGCCATCG
TGCGGCGCGATGCGGGGCTGGGCGTGACGGTGGTGGTTTCGCCGCTGATCGCGCTGATGCACGACCAGGTGGGCGCGCTG
CACGAGGCGGGGGTGGAGGCGGCCTTCCTCAACTCCACGCTGGACTGGCAGCAGACGCAGGACGTGGAGAGGCGCCTGGC
GCGCGGCGAGATCACGCTGCTGTACGCCGCGCCCGAGCGCGTGACCACCGACCGCTTTCTCACGCTGCTGGACGGTCTGC
ATGCGCGCGGGCAGCTCGGGCTGTTCGCCATCGACGAGGCGCACTGCGTGAGCCAGTGGGGCCACGACTTCCGCCCCGAA
TACCGCCAGCTCGCGGTGCTGCACGAGCGCTATGCGGGCGTGCCGCGCATTGCCCTCACGGCCACGGCGGACGCGCTCAC
GCGCGAGGACATCGTGCAGGGCCTGCGGCTGCAGCAGGCGCGGCAGTTCGTCAGCAGCTTCGACCGGCCCAACATCCGCT
ACCGCATCGAGGAAAAGAAGGAGCCGCTCACGCAGCTCATGCGCTTCATCGACCGCGAGCACCTGGGCGAGGCCGGCGTG
GTCTATTGCCAGTCCCGCAAGCGCGTGGAGGAACTGGCCCAGGCGCTGTGCGATGCGGGCCTGACGGCGCTGCCCTACCA
CGCGGGCCTGCCCGCCGAGGTGCGCCAGCAGAACCAGGACCGCTTCCTGCGCGAGGACGGCATCGTGATGGTGGCCACCA
TCGCCTTCGGCATGGGCATCGACAAGCCCGACGTGCGCTTTGTGGCCCATGTGGACATGCCCAAGAACATTGAGGGCTAC
TACCAGGAGACGGGCCGCGCGGGCCGCGACGGTCTGCCCGCCGACGCGTGGATGGCCTACGGCCTGCAGGACGTGGTGAA
CCAGCGCCGCATGATCGACGAGAGCCCCGCGGGCGAGGAGTTCAAGGCCGTGATGCGCGGCAAGCTCGATGCGCTGCTGG
CCCTGGCCGAGGCCACGGACTGCCGGCGCGTGCGGCTGCTGGGCTACTTCGGCGAGGCGTCCGAACCCTGCGGCAATTGC
GACAACTGCCTGAATCCGCCGGCCGTGTGGGACGGCACGGATGCCGCGCGCAAGCTCCTGTCCACCATCTATCGCGTGCA
CGAGGCCAGCGGCCTGACCTTCGGCACGGGCCACATCATGGACATCCTGCGCGGCAAGGCCACGGACAAGGTCCAGCAGT
TCGGCCATGAAAAACTCTCCACCTTCGGCCTGGGCGCACAGTATTCCGAGGCGCAGCTGCGCGGCGTGCTGCGCCAGTTG
CTGGCCGCCGGCGCCGTGGGGCTGCACAAGGTCACGACCGAGGGCGGCCACAGCTTTGACACGCTGGCGCTGACCGAGGG
ATCGCGCCCCGTGCTGCGCGGCGAGCAGAGCGTGCTGCTGCGCGAGGCCACGGCCGCGGCCGGCCCCAAGAAGCCGCGCC
GCGCCAGCGCCCCGCCGGTGGCAGCGGCCAACCTGGGACAGGACGCCCAGGTGCGCTTCATCAACCTCAAGGCCTGGCGC
GCCGAGGTGGCGCGCGAGCACAACCTGCCGGCCTACGTGATCTTCCACGACGCCACGCTGGCCGCTATTGCCGAGCGCAA
CCCGGCCACGCTGGAGGATCTGCAGGGCATCAGCGGCATGGGTGCGAAAAAGCTGGAGGCGTACGGCGCCGAAGTGCTGC
GGGTGTGCGGCGCCGGGGCCGCGGCCGGCTGA

Upstream 100 bases:

>100_bases
CATGGCCGGTCGGTCTGCAGGACTGCGTTTCACAGGCCAAAAGTGCCTCTAGCGCTTATCCAGCAAGCGCTAACAGCTAT
TAAAAAGAGAGTCTACCGAT

Downstream 100 bases:

>100_bases
TCAGGCGCACCGCAGGCTGGTGGGCAGCGGCCACTGCGTGGGGCGGCGCCGTACGGCACCAGGGCACGCTGGCGGGCGTG
CTGCATTCCTGCAGCACCCA

Product: ATP-dependent DNA helicase recq

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 623; Mature: 622

Protein sequence:

>623_residues
MSPAHFVLHDVFGYEQFRGPQQAIIDHVIAGGDALVLMPTGGGKSLCYQVPAIVRRDAGLGVTVVVSPLIALMHDQVGAL
HEAGVEAAFLNSTLDWQQTQDVERRLARGEITLLYAAPERVTTDRFLTLLDGLHARGQLGLFAIDEAHCVSQWGHDFRPE
YRQLAVLHERYAGVPRIALTATADALTREDIVQGLRLQQARQFVSSFDRPNIRYRIEEKKEPLTQLMRFIDREHLGEAGV
VYCQSRKRVEELAQALCDAGLTALPYHAGLPAEVRQQNQDRFLREDGIVMVATIAFGMGIDKPDVRFVAHVDMPKNIEGY
YQETGRAGRDGLPADAWMAYGLQDVVNQRRMIDESPAGEEFKAVMRGKLDALLALAEATDCRRVRLLGYFGEASEPCGNC
DNCLNPPAVWDGTDAARKLLSTIYRVHEASGLTFGTGHIMDILRGKATDKVQQFGHEKLSTFGLGAQYSEAQLRGVLRQL
LAAGAVGLHKVTTEGGHSFDTLALTEGSRPVLRGEQSVLLREATAAAGPKKPRRASAPPVAAANLGQDAQVRFINLKAWR
AEVAREHNLPAYVIFHDATLAAIAERNPATLEDLQGISGMGAKKLEAYGAEVLRVCGAGAAAG

Sequences:

>Translated_623_residues
MSPAHFVLHDVFGYEQFRGPQQAIIDHVIAGGDALVLMPTGGGKSLCYQVPAIVRRDAGLGVTVVVSPLIALMHDQVGAL
HEAGVEAAFLNSTLDWQQTQDVERRLARGEITLLYAAPERVTTDRFLTLLDGLHARGQLGLFAIDEAHCVSQWGHDFRPE
YRQLAVLHERYAGVPRIALTATADALTREDIVQGLRLQQARQFVSSFDRPNIRYRIEEKKEPLTQLMRFIDREHLGEAGV
VYCQSRKRVEELAQALCDAGLTALPYHAGLPAEVRQQNQDRFLREDGIVMVATIAFGMGIDKPDVRFVAHVDMPKNIEGY
YQETGRAGRDGLPADAWMAYGLQDVVNQRRMIDESPAGEEFKAVMRGKLDALLALAEATDCRRVRLLGYFGEASEPCGNC
DNCLNPPAVWDGTDAARKLLSTIYRVHEASGLTFGTGHIMDILRGKATDKVQQFGHEKLSTFGLGAQYSEAQLRGVLRQL
LAAGAVGLHKVTTEGGHSFDTLALTEGSRPVLRGEQSVLLREATAAAGPKKPRRASAPPVAAANLGQDAQVRFINLKAWR
AEVAREHNLPAYVIFHDATLAAIAERNPATLEDLQGISGMGAKKLEAYGAEVLRVCGAGAAAG
>Mature_622_residues
SPAHFVLHDVFGYEQFRGPQQAIIDHVIAGGDALVLMPTGGGKSLCYQVPAIVRRDAGLGVTVVVSPLIALMHDQVGALH
EAGVEAAFLNSTLDWQQTQDVERRLARGEITLLYAAPERVTTDRFLTLLDGLHARGQLGLFAIDEAHCVSQWGHDFRPEY
RQLAVLHERYAGVPRIALTATADALTREDIVQGLRLQQARQFVSSFDRPNIRYRIEEKKEPLTQLMRFIDREHLGEAGVV
YCQSRKRVEELAQALCDAGLTALPYHAGLPAEVRQQNQDRFLREDGIVMVATIAFGMGIDKPDVRFVAHVDMPKNIEGYY
QETGRAGRDGLPADAWMAYGLQDVVNQRRMIDESPAGEEFKAVMRGKLDALLALAEATDCRRVRLLGYFGEASEPCGNCD
NCLNPPAVWDGTDAARKLLSTIYRVHEASGLTFGTGHIMDILRGKATDKVQQFGHEKLSTFGLGAQYSEAQLRGVLRQLL
AAGAVGLHKVTTEGGHSFDTLALTEGSRPVLRGEQSVLLREATAAAGPKKPRRASAPPVAAANLGQDAQVRFINLKAWRA
EVAREHNLPAYVIFHDATLAAIAERNPATLEDLQGISGMGAKKLEAYGAEVLRVCGAGAAAG

Specific function: Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI4557365, Length=637, Percent_Identity=33.5949764521193, Blast_Score=349, Evalue=4e-96,
Organism=Homo sapiens, GI14591902, Length=438, Percent_Identity=35.6164383561644, Blast_Score=289, Evalue=5e-78,
Organism=Homo sapiens, GI14591904, Length=438, Percent_Identity=35.6164383561644, Blast_Score=289, Evalue=5e-78,
Organism=Homo sapiens, GI148612816, Length=428, Percent_Identity=39.4859813084112, Blast_Score=278, Evalue=1e-74,
Organism=Homo sapiens, GI110735439, Length=566, Percent_Identity=33.3922261484099, Blast_Score=261, Evalue=1e-69,
Organism=Homo sapiens, GI169218196, Length=566, Percent_Identity=33.3922261484099, Blast_Score=260, Evalue=3e-69,
Organism=Homo sapiens, GI51242947, Length=355, Percent_Identity=41.6901408450704, Blast_Score=258, Evalue=1e-68,
Organism=Homo sapiens, GI51242943, Length=355, Percent_Identity=41.6901408450704, Blast_Score=258, Evalue=1e-68,
Organism=Homo sapiens, GI284005309, Length=384, Percent_Identity=33.59375, Blast_Score=180, Evalue=4e-45,
Organism=Escherichia coli, GI48994977, Length=611, Percent_Identity=47.7905073649754, Blast_Score=537, Evalue=1e-154,
Organism=Caenorhabditis elegans, GI25145561, Length=652, Percent_Identity=35.8895705521472, Blast_Score=339, Evalue=2e-93,
Organism=Caenorhabditis elegans, GI32564293, Length=668, Percent_Identity=31.437125748503, Blast_Score=302, Evalue=4e-82,
Organism=Caenorhabditis elegans, GI71987997, Length=409, Percent_Identity=39.119804400978, Blast_Score=297, Evalue=1e-80,
Organism=Caenorhabditis elegans, GI71987993, Length=409, Percent_Identity=39.119804400978, Blast_Score=297, Evalue=1e-80,
Organism=Caenorhabditis elegans, GI17552866, Length=439, Percent_Identity=37.3576309794989, Blast_Score=261, Evalue=8e-70,
Organism=Caenorhabditis elegans, GI17555296, Length=379, Percent_Identity=23.4828496042216, Blast_Score=69, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6323844, Length=543, Percent_Identity=33.1491712707182, Blast_Score=331, Evalue=3e-91,
Organism=Saccharomyces cerevisiae, GI6319714, Length=373, Percent_Identity=21.71581769437, Blast_Score=70, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24646066, Length=635, Percent_Identity=36.0629921259843, Blast_Score=371, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24664226, Length=437, Percent_Identity=37.070938215103, Blast_Score=273, Evalue=3e-73,
Organism=Drosophila melanogaster, GI24664230, Length=437, Percent_Identity=37.070938215103, Blast_Score=271, Evalue=1e-72,
Organism=Drosophila melanogaster, GI62472181, Length=437, Percent_Identity=37.5286041189931, Blast_Score=270, Evalue=2e-72,
Organism=Drosophila melanogaster, GI21358123, Length=352, Percent_Identity=36.3636363636364, Blast_Score=201, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 67945; Mature: 67814

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPAHFVLHDVFGYEQFRGPQQAIIDHVIAGGDALVLMPTGGGKSLCYQVPAIVRRDAGL
CCCHHHHHHHHHCHHHHCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCC
GVTVVVSPLIALMHDQVGALHEAGVEAAFLNSTLDWQQTQDVERRLARGEITLLYAAPER
CHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHCCCEEEEEECCCH
VTTDRFLTLLDGLHARGQLGLFAIDEAHCVSQWGHDFRPEYRQLAVLHERYAGVPRIALT
HHHHHHHHHHHCCCCCCCCCEEEECHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEE
ATADALTREDIVQGLRLQQARQFVSSFDRPNIRYRIEEKKEPLTQLMRFIDREHLGEAGV
ECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCE
VYCQSRKRVEELAQALCDAGLTALPYHAGLPAEVRQQNQDRFLREDGIVMVATIAFGMGI
EEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCHHHHHHHHCCEEEEEEHHHHCCC
DKPDVRFVAHVDMPKNIEGYYQETGRAGRDGLPADAWMAYGLQDVVNQRRMIDESPAGEE
CCCCCEEEEEECCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHH
FKAVMRGKLDALLALAEATDCRRVRLLGYFGEASEPCGNCDNCLNPPAVWDGTDAARKLL
HHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
STIYRVHEASGLTFGTGHIMDILRGKATDKVQQFGHEKLSTFGLGAQYSEAQLRGVLRQL
HHHHHHHHHCCCEECHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
LAAGAVGLHKVTTEGGHSFDTLALTEGSRPVLRGEQSVLLREATAAAGPKKPRRASAPPV
HHHCCCCCEEEECCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
AAANLGQDAQVRFINLKAWRAEVAREHNLPAYVIFHDATLAAIAERNPATLEDLQGISGM
HHHCCCCCCEEEEEEHHHHHHHHHHHCCCCEEEEEECCHHHHHHCCCCCCHHHHCCCCCC
GAKKLEAYGAEVLRVCGAGAAAG
CHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SPAHFVLHDVFGYEQFRGPQQAIIDHVIAGGDALVLMPTGGGKSLCYQVPAIVRRDAGL
CCHHHHHHHHHCHHHHCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCC
GVTVVVSPLIALMHDQVGALHEAGVEAAFLNSTLDWQQTQDVERRLARGEITLLYAAPER
CHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHCCCEEEEEECCCH
VTTDRFLTLLDGLHARGQLGLFAIDEAHCVSQWGHDFRPEYRQLAVLHERYAGVPRIALT
HHHHHHHHHHHCCCCCCCCCEEEECHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEE
ATADALTREDIVQGLRLQQARQFVSSFDRPNIRYRIEEKKEPLTQLMRFIDREHLGEAGV
ECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCE
VYCQSRKRVEELAQALCDAGLTALPYHAGLPAEVRQQNQDRFLREDGIVMVATIAFGMGI
EEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCHHHHHHHHCCEEEEEEHHHHCCC
DKPDVRFVAHVDMPKNIEGYYQETGRAGRDGLPADAWMAYGLQDVVNQRRMIDESPAGEE
CCCCCEEEEEECCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHH
FKAVMRGKLDALLALAEATDCRRVRLLGYFGEASEPCGNCDNCLNPPAVWDGTDAARKLL
HHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
STIYRVHEASGLTFGTGHIMDILRGKATDKVQQFGHEKLSTFGLGAQYSEAQLRGVLRQL
HHHHHHHHHCCCEECHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
LAAGAVGLHKVTTEGGHSFDTLALTEGSRPVLRGEQSVLLREATAAAGPKKPRRASAPPV
HHHCCCCCEEEECCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
AAANLGQDAQVRFINLKAWRAEVAREHNLPAYVIFHDATLAAIAERNPATLEDLQGISGM
HHHCCCCCCEEEEEEHHHHHHHHHHHCCCCEEEEEECCHHHHHHCCCCCCHHHHCCCCCC
GAKKLEAYGAEVLRVCGAGAAAG
CHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3027506; 1379743; 9278503; 2164680 [H]