Click here to switch to the map view.

The map label for this gene is wrbA

Identifier: 222109282

GI number: 222109282

Start: 60623

End: 61225

Strand: Direct

Name: wrbA

Synonym: Dtpsy_0057

Alternate gene names: 222109282

Gene position: 60623-61225 (Clockwise)

Preceding gene: 222109281

Following gene: 222109288

Centisome position: 1.6

GC content: 68.66

Gene sequence:

>603_bases
ATGTCCAAGGTACTCGTTCTCTACTACTCGACTTACGGCCATCTCGAAACCATGGCGCAGGCCGTCGCCGAAGGCGCGCG
CTCTGCCGGTGCCACGGTGGACGTGAAGCGCGTTCCCGAAACGGTGCCGCAGGAGATCGCCCGGTCCGCGCACTTCAAGC
TGGACCAGTCCGCACCCGTCGCCACCGTGACCGAGCTGGAAAACTACGACGCGATCATCGTCGGCGCGCCCACGCGCTTT
GGCCGCATGCCCTCGCAGATGGGCAGCTTCCTCGACCAGGCGGGCGGCCTGTGGGCGCGCGGCGCCCTCAACGGCAAGGT
GGGCGCGGCGTTCACCTCCACCGCCACGCAGCACGGCGGGCAGGAGACGACGCTGTTTTCCATCATCACCAACCTGCTGC
ACTTCGGCATGGTGATCGTGGGGCTGCCCTACAGCTTCCAGGGCCAGATGACGCTGGACGAAGTGGTGGGCGGCGCCCCC
TACGGTGCGACCACCATCGCCGGCGGCCAGGGCCAGCGCCAGCCCAGCGCGACCGAGCTGGACGGCGCACGCTTCCAGGG
CCGTCTGGTGGCCGAGACGGCCAACAAGCTGTTCGGGGGCTGA

Upstream 100 bases:

>100_bases
GGGTGCCTCTGTGTGCTGGCCCATGAAGGCGGCGGGGTGCTGCGCGCGCTGCCAGCCATGCTGCTTGTGGCTGCACAAGC
GTTCTTGAAAAGGGAAAGTC

Downstream 100 bases:

>100_bases
GTCGTTACGCCAGAGTCCCGCAGGGCGTGCGCCTTGCGTGGCCGTACACCAGCGGGAGCAAGCCTCGCGGTAAAGCACAA
GCGCAGCTGCGTGCGGGTGG

Product: flavoprotein wrba

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MSKVLVLYYSTYGHLETMAQAVAEGARSAGATVDVKRVPETVPQEIARSAHFKLDQSAPVATVTELENYDAIIVGAPTRF
GRMPSQMGSFLDQAGGLWARGALNGKVGAAFTSTATQHGGQETTLFSIITNLLHFGMVIVGLPYSFQGQMTLDEVVGGAP
YGATTIAGGQGQRQPSATELDGARFQGRLVAETANKLFGG

Sequences:

>Translated_200_residues
MSKVLVLYYSTYGHLETMAQAVAEGARSAGATVDVKRVPETVPQEIARSAHFKLDQSAPVATVTELENYDAIIVGAPTRF
GRMPSQMGSFLDQAGGLWARGALNGKVGAAFTSTATQHGGQETTLFSIITNLLHFGMVIVGLPYSFQGQMTLDEVVGGAP
YGATTIAGGQGQRQPSATELDGARFQGRLVAETANKLFGG
>Mature_199_residues
SKVLVLYYSTYGHLETMAQAVAEGARSAGATVDVKRVPETVPQEIARSAHFKLDQSAPVATVTELENYDAIIVGAPTRFG
RMPSQMGSFLDQAGGLWARGALNGKVGAAFTSTATQHGGQETTLFSIITNLLHFGMVIVGLPYSFQGQMTLDEVVGGAPY
GATTIAGGQGQRQPSATELDGARFQGRLVAETANKLFGG

Specific function: Seems To Enhance The Formation And/Or Stability Of Noncovalent Complexes Between The Trp Repressor Protein And Operator-Bearing DNA. However, Wrba Does Not Specifically Influence The Affinity Or Mode Of Binding Of Trpr To Its Operator. It Seems Possible T

COG id: COG0655

COG function: function code R; Multimeric flavodoxin WrbA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain

Homologues:

Organism=Escherichia coli, GI1787239, Length=200, Percent_Identity=60.5, Blast_Score=213, Evalue=9e-57,
Organism=Saccharomyces cerevisiae, GI6319849, Length=201, Percent_Identity=44.2786069651741, Blast_Score=174, Evalue=6e-45,
Organism=Saccharomyces cerevisiae, GI6320235, Length=199, Percent_Identity=41.7085427135678, Blast_Score=156, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6319526, Length=201, Percent_Identity=31.8407960199005, Blast_Score=102, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): WRBA_ACIET (B9M9X5)

Other databases:

- EMBL:   CP001392
- RefSeq:   YP_002551546.1
- ProteinModelPortal:   B9M9X5
- GeneID:   7382748
- GenomeReviews:   CP001392_GR
- KEGG:   dia:Dtpsy_0057
- HAMAP:   MF_01017
- InterPro:   IPR008254
- InterPro:   IPR010089
- InterPro:   IPR005025
- TIGRFAMs:   TIGR01755

Pfam domain/function: PF03358 FMN_red

EC number: NA

Molecular weight: Translated: 20998; Mature: 20867

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50902 FLAVODOXIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKVLVLYYSTYGHLETMAQAVAEGARSAGATVDVKRVPETVPQEIARSAHFKLDQSAPV
CCCEEEEEECCHHHHHHHHHHHHHHHHHCCCEEEHHHCCHHHHHHHHHHHCCCCCCCCCC
ATVTELENYDAIIVGAPTRFGRMPSQMGSFLDQAGGLWARGALNGKVGAAFTSTATQHGG
EEEECCCCCCEEEEECCHHHCCCHHHHHHHHHHHCCEEECCCCCCCCCCHHHHHHHHCCC
QETTLFSIITNLLHFGMVIVGLPYSFQGQMTLDEVVGGAPYGATTIAGGQGQRQPSATEL
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHCCCCCCCEEEECCCCCCCCCCCCC
DGARFQGRLVAETANKLFGG
CCCHHCCCHHHHHHHHHCCC
>Mature Secondary Structure 
SKVLVLYYSTYGHLETMAQAVAEGARSAGATVDVKRVPETVPQEIARSAHFKLDQSAPV
CCEEEEEECCHHHHHHHHHHHHHHHHHCCCEEEHHHCCHHHHHHHHHHHCCCCCCCCCC
ATVTELENYDAIIVGAPTRFGRMPSQMGSFLDQAGGLWARGALNGKVGAAFTSTATQHGG
EEEECCCCCCEEEEECCHHHCCCHHHHHHHHHHHCCEEECCCCCCCCCCHHHHHHHHCCC
QETTLFSIITNLLHFGMVIVGLPYSFQGQMTLDEVVGGAPYGATTIAGGQGQRQPSATEL
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHCCCCCCCEEEECCCCCCCCCCCCC
DGARFQGRLVAETANKLFGG
CCCHHCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA