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The map label for this gene is mnmG [H]

Identifier: 222109270

GI number: 222109270

Start: 48425

End: 50398

Strand: Direct

Name: mnmG [H]

Synonym: Dtpsy_0045

Alternate gene names: 222109270

Gene position: 48425-50398 (Clockwise)

Preceding gene: 222109263

Following gene: 222109271

Centisome position: 1.28

GC content: 65.45

Gene sequence:

>1974_bases
ATGTTGTACCCCCAGGATTTCGATGTCATCGTCGTTGGCGGAGGCCATGCCGGCACCGAGGCCGCGCTGGCCGCCGCGCG
CATGGGCAGCCGCACGCTGCTGCTCACGCACAACATCGAGACGCTGGGGCAGATGAGTTGCAACCCCAGCATCGGCGGCA
TTGGCAAGGGCCACCTGGTGAAGGAGGTGGACGCGCTGGGCGGCGCCATGGCGCTGGCGACCGATGAGGCGGGCATCCAG
TTCCGCATCCTCAACAGCAGCAAGGGCCCGGCCGTGCGCGCCACGCGTGCGCAGGCCGACCGCATCCTCTACAAGGCGGC
CATCCGCCGCATGCTGGAGAACCAACCCAACCTGTGGTTGTTCCAGCAGGCGGTGGACGACCTGATGGTGGAGGGCGACC
GCGTGGTGGGCGCCGTCACGCAGGTGGGCATCCGCTTTCGCAGTCGCGCGGTGGTGCTGACGGCGGGCACCTTCTTGGAC
GGCAAGATCCATGTGGGTCTGAACAACTACGCGGCCGGCCGCGCGGGGGATCCTCCGGCCGTAAGCCTGTCGGCACGCCT
GAAGGAGCTGCAGTTGCCCCAGGGACGCTTGAAGACCGGCACGCCGCCGCGCATCGACGGGCGCAGCATCGACTTCAGCC
AGTGTGAGGAGCAGCCCGGCGACGGCATGCCCGGCGGTGTGAACGAGGGTGCTGTGCCTGTGTTCAGCTTCATGGGCAAT
GCGGCCATGCACCCGCGCCAGGTGCCCTGCTGGATCACGCACACCAACGCGCGCACGCACGAGATCATCCGCAGCGGCTT
TGACCGCAGTCCCATGTTCACCGGCAAGATCGAGGGCGTGGGCCCGCGCTACTGCCCCAGCGTGGAGGACAAGATCAACC
GCTTTGCCGACAAGGAAAGCCATCAGATCTTTCTGGAGCCGGAAGGGCTGACCACGCACGAGTTCTACCCCAACGGCATC
AGCACCAGCCTGCCGTTCGATATCCAGTACGACCTGGTGCGCTCGATGCGCGGCCTGGAGAACGCGCACATTCTGCGGCC
GGGCTACGCCATCGAGTACGACTACTTCGACCCGCGTTCGCTCAAGAGCAGTTTCGAGACGCGGCAGATCCAGGGCCTGT
TCTTCGCGGGCCAAATCAATGGCACCACAGGGTACGAGGAGGCGGCGGCGCAGGGCCTGTTCGCCGGTATCAACGCCGCG
CTGCAATGCCGAGGGGAGCGTGCCTGGGTGCCCGCGCGCGACGAGGCCTATCTGGGCGTGTTGGTGGACGATCTGATCAC
CAAGGGCGTGACCGAGCCCTACCGCATGTTCACCAGCCGCGCCGAGTTCCGCCTGCAGCTGCGCGAGGACAACGCCGACA
TGCGCCTGACCGATGCGGGGCGTCGCATGGGTTTGGTGGACGATGCGCGCTGGGACGCTTTCAGCCGCAAGCGCGATGCG
GTTTCACGTGAAACAGAGCGTTTGAAATCGACATGGGTGAACCCGCGCAACCTGCCCACGGTGGAGGCCGAGCGCGTGCT
GGGTAAAGCCATCGAACATGAATACAACCTCTTCGACCTGTTGCGCCGTCCGGACGTGGGGTATGACGCACTGACGACCA
TGGATGGCGGCAAGTATGCGAGCGAGGCTGTTTCACGTGAAACGTTGGGCGAGCTGAGTGCGCCCGTGATCGAGCAGGTC
GAGATTGCCGCCAAGTACGCGGGCTATATCGAGCGCCAACGGGACGAGGTGCAGCGCGCCGCGCACTTCGAAAAGCTGCG
CCTGCCCGAAGATCTGGACTACATGCAAGTGGCGGCCTTGTCGATTGAGGTGCGGCAAAAACTGCAGAAGCACCGGCCGG
AGACGTTGGGCCAGGCGTCGCGTATTTCCGGGGTGACACCGGCGGCGATCTCGCTGCTGATGGTCCACTTGAAGAAGGGC
GGTTTCAAGGGGTTTGCCCCGCAGCCGGCGGATGGGGTGGAGACGGTCGCATGA

Upstream 100 bases:

>100_bases
GCCGGCAGCGCAGGCGCGAGGGTGGGGGCGGTACCGGCGCCGTGAAAGCCGGGCTTGTTCACCGTTTGACAGGGCCGCAG
CGGGCCCGGAGCACCCCACC

Downstream 100 bases:

>100_bases
GCGTGGTGTCGAACACAAGCCTTGAGCACGCCTTGCGTGAGGGCGCCAACGCCTTGGGGTTGGATCTGTCGGAAGCGCAA
ATCACACAGCTATTGGACTT

Product: tRNA uridine 5-carboxymethylaminomethyl modification protein GidA

Products: NA

Alternate protein names: Glucose-inhibited division protein A [H]

Number of amino acids: Translated: 657; Mature: 657

Protein sequence:

>657_residues
MLYPQDFDVIVVGGGHAGTEAALAAARMGSRTLLLTHNIETLGQMSCNPSIGGIGKGHLVKEVDALGGAMALATDEAGIQ
FRILNSSKGPAVRATRAQADRILYKAAIRRMLENQPNLWLFQQAVDDLMVEGDRVVGAVTQVGIRFRSRAVVLTAGTFLD
GKIHVGLNNYAAGRAGDPPAVSLSARLKELQLPQGRLKTGTPPRIDGRSIDFSQCEEQPGDGMPGGVNEGAVPVFSFMGN
AAMHPRQVPCWITHTNARTHEIIRSGFDRSPMFTGKIEGVGPRYCPSVEDKINRFADKESHQIFLEPEGLTTHEFYPNGI
STSLPFDIQYDLVRSMRGLENAHILRPGYAIEYDYFDPRSLKSSFETRQIQGLFFAGQINGTTGYEEAAAQGLFAGINAA
LQCRGERAWVPARDEAYLGVLVDDLITKGVTEPYRMFTSRAEFRLQLREDNADMRLTDAGRRMGLVDDARWDAFSRKRDA
VSRETERLKSTWVNPRNLPTVEAERVLGKAIEHEYNLFDLLRRPDVGYDALTTMDGGKYASEAVSRETLGELSAPVIEQV
EIAAKYAGYIERQRDEVQRAAHFEKLRLPEDLDYMQVAALSIEVRQKLQKHRPETLGQASRISGVTPAAISLLMVHLKKG
GFKGFAPQPADGVETVA

Sequences:

>Translated_657_residues
MLYPQDFDVIVVGGGHAGTEAALAAARMGSRTLLLTHNIETLGQMSCNPSIGGIGKGHLVKEVDALGGAMALATDEAGIQ
FRILNSSKGPAVRATRAQADRILYKAAIRRMLENQPNLWLFQQAVDDLMVEGDRVVGAVTQVGIRFRSRAVVLTAGTFLD
GKIHVGLNNYAAGRAGDPPAVSLSARLKELQLPQGRLKTGTPPRIDGRSIDFSQCEEQPGDGMPGGVNEGAVPVFSFMGN
AAMHPRQVPCWITHTNARTHEIIRSGFDRSPMFTGKIEGVGPRYCPSVEDKINRFADKESHQIFLEPEGLTTHEFYPNGI
STSLPFDIQYDLVRSMRGLENAHILRPGYAIEYDYFDPRSLKSSFETRQIQGLFFAGQINGTTGYEEAAAQGLFAGINAA
LQCRGERAWVPARDEAYLGVLVDDLITKGVTEPYRMFTSRAEFRLQLREDNADMRLTDAGRRMGLVDDARWDAFSRKRDA
VSRETERLKSTWVNPRNLPTVEAERVLGKAIEHEYNLFDLLRRPDVGYDALTTMDGGKYASEAVSRETLGELSAPVIEQV
EIAAKYAGYIERQRDEVQRAAHFEKLRLPEDLDYMQVAALSIEVRQKLQKHRPETLGQASRISGVTPAAISLLMVHLKKG
GFKGFAPQPADGVETVA
>Mature_657_residues
MLYPQDFDVIVVGGGHAGTEAALAAARMGSRTLLLTHNIETLGQMSCNPSIGGIGKGHLVKEVDALGGAMALATDEAGIQ
FRILNSSKGPAVRATRAQADRILYKAAIRRMLENQPNLWLFQQAVDDLMVEGDRVVGAVTQVGIRFRSRAVVLTAGTFLD
GKIHVGLNNYAAGRAGDPPAVSLSARLKELQLPQGRLKTGTPPRIDGRSIDFSQCEEQPGDGMPGGVNEGAVPVFSFMGN
AAMHPRQVPCWITHTNARTHEIIRSGFDRSPMFTGKIEGVGPRYCPSVEDKINRFADKESHQIFLEPEGLTTHEFYPNGI
STSLPFDIQYDLVRSMRGLENAHILRPGYAIEYDYFDPRSLKSSFETRQIQGLFFAGQINGTTGYEEAAAQGLFAGINAA
LQCRGERAWVPARDEAYLGVLVDDLITKGVTEPYRMFTSRAEFRLQLREDNADMRLTDAGRRMGLVDDARWDAFSRKRDA
VSRETERLKSTWVNPRNLPTVEAERVLGKAIEHEYNLFDLLRRPDVGYDALTTMDGGKYASEAVSRETLGELSAPVIEQV
EIAAKYAGYIERQRDEVQRAAHFEKLRLPEDLDYMQVAALSIEVRQKLQKHRPETLGQASRISGVTPAAISLLMVHLKKG
GFKGFAPQPADGVETVA

Specific function: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 [H]

COG id: COG0445

COG function: function code D; NAD/FAD-utilizing enzyme apparently involved in cell division

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MnmG family [H]

Homologues:

Organism=Homo sapiens, GI74024895, Length=646, Percent_Identity=45.046439628483, Blast_Score=496, Evalue=1e-140,
Organism=Homo sapiens, GI19882217, Length=671, Percent_Identity=43.3681073025335, Blast_Score=483, Evalue=1e-136,
Organism=Homo sapiens, GI183227703, Length=686, Percent_Identity=42.4198250728863, Blast_Score=477, Evalue=1e-134,
Organism=Escherichia coli, GI2367273, Length=642, Percent_Identity=65.8878504672897, Blast_Score=862, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17534255, Length=644, Percent_Identity=41.304347826087, Blast_Score=471, Evalue=1e-133,
Organism=Saccharomyces cerevisiae, GI6321202, Length=635, Percent_Identity=43.7795275590551, Blast_Score=501, Evalue=1e-142,
Organism=Drosophila melanogaster, GI24658174, Length=653, Percent_Identity=45.4823889739663, Blast_Score=508, Evalue=1e-144,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004416
- InterPro:   IPR002218
- InterPro:   IPR020595 [H]

Pfam domain/function: PF01134 GIDA [H]

EC number: NA

Molecular weight: Translated: 72345; Mature: 72345

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS01280 GIDA_1 ; PS01281 GIDA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYPQDFDVIVVGGGHAGTEAALAAARMGSRTLLLTHNIETLGQMSCNPSIGGIGKGHLV
CCCCCCCCEEEECCCCCCHHHHHHHHHCCCEEEEEEECHHHHHCCCCCCCCCCCCCCHHH
KEVDALGGAMALATDEAGIQFRILNSSKGPAVRATRAQADRILYKAAIRRMLENQPNLWL
HHHHHCCCEEEEEECCCCEEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCEEE
FQQAVDDLMVEGDRVVGAVTQVGIRFRSRAVVLTAGTFLDGKIHVGLNNYAAGRAGDPPA
HHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECEEECCEEEECCCCCCCCCCCCCCC
VSLSARLKELQLPQGRLKTGTPPRIDGRSIDFSQCEEQPGDGMPGGVNEGAVPVFSFMGN
EEHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHCC
AAMHPRQVPCWITHTNARTHEIIRSGFDRSPMFTGKIEGVGPRYCPSVEDKINRFADKES
CCCCCCCCCEEEEECCCHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCC
HQIFLEPEGLTTHEFYPNGISTSLPFDIQYDLVRSMRGLENAHILRPGYAIEYDYFDPRS
CEEEECCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEECCCEEEEECCCCCHH
LKSSFETRQIQGLFFAGQINGTTGYEEAAAQGLFAGINAALQCRGERAWVPARDEAYLGV
HHHHHHHHHEEEEEEEEEECCCCCHHHHHHHHHHHHCCHHEEECCCCCCCCCCCCCHHHH
LVDDLITKGVTEPYRMFTSRAEFRLQLREDNADMRLTDAGRRMGLVDDARWDAFSRKRDA
HHHHHHHHCCCHHHHHHHCCCEEEEEEECCCCCEEEECCCCCCCCCCCCHHHHHHHHHHH
VSRETERLKSTWVNPRNLPTVEAERVLGKAIEHEYNLFDLLRRPDVGYDALTTMDGGKYA
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHCCCCCCHHEEECCCCHHH
SEAVSRETLGELSAPVIEQVEIAAKYAGYIERQRDEVQRAAHFEKLRLPEDLDYMQVAAL
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
SIEVRQKLQKHRPETLGQASRISGVTPAAISLLMVHLKKGGFKGFAPQPADGVETVA
HHHHHHHHHHCCCHHHCCHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLYPQDFDVIVVGGGHAGTEAALAAARMGSRTLLLTHNIETLGQMSCNPSIGGIGKGHLV
CCCCCCCCEEEECCCCCCHHHHHHHHHCCCEEEEEEECHHHHHCCCCCCCCCCCCCCHHH
KEVDALGGAMALATDEAGIQFRILNSSKGPAVRATRAQADRILYKAAIRRMLENQPNLWL
HHHHHCCCEEEEEECCCCEEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCEEE
FQQAVDDLMVEGDRVVGAVTQVGIRFRSRAVVLTAGTFLDGKIHVGLNNYAAGRAGDPPA
HHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECEEECCEEEECCCCCCCCCCCCCCC
VSLSARLKELQLPQGRLKTGTPPRIDGRSIDFSQCEEQPGDGMPGGVNEGAVPVFSFMGN
EEHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHCC
AAMHPRQVPCWITHTNARTHEIIRSGFDRSPMFTGKIEGVGPRYCPSVEDKINRFADKES
CCCCCCCCCEEEEECCCHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCC
HQIFLEPEGLTTHEFYPNGISTSLPFDIQYDLVRSMRGLENAHILRPGYAIEYDYFDPRS
CEEEECCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEECCCEEEEECCCCCHH
LKSSFETRQIQGLFFAGQINGTTGYEEAAAQGLFAGINAALQCRGERAWVPARDEAYLGV
HHHHHHHHHEEEEEEEEEECCCCCHHHHHHHHHHHHCCHHEEECCCCCCCCCCCCCHHHH
LVDDLITKGVTEPYRMFTSRAEFRLQLREDNADMRLTDAGRRMGLVDDARWDAFSRKRDA
HHHHHHHHCCCHHHHHHHCCCEEEEEEECCCCCEEEECCCCCCCCCCCCHHHHHHHHHHH
VSRETERLKSTWVNPRNLPTVEAERVLGKAIEHEYNLFDLLRRPDVGYDALTTMDGGKYA
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHCCCCCCHHEEECCCCHHH
SEAVSRETLGELSAPVIEQVEIAAKYAGYIERQRDEVQRAAHFEKLRLPEDLDYMQVAAL
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
SIEVRQKLQKHRPETLGQASRISGVTPAAISLLMVHLKKGGFKGFAPQPADGVETVA
HHHHHHHHHHCCCHHHCCHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA