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The map label for this gene is aroG [H]

Identifier: 222109245

GI number: 222109245

Start: 19509

End: 20609

Strand: Direct

Name: aroG [H]

Synonym: Dtpsy_0020

Alternate gene names: 222109245

Gene position: 19509-20609 (Clockwise)

Preceding gene: 222109244

Following gene: 222109246

Centisome position: 0.51

GC content: 69.03

Gene sequence:

>1101_bases
ATGACCCTGACCGAACGCCTCGCATCCCCGCTCACCACCCACGACACCACGCGCATCGACGACCTGCGCATCAAAGCCGT
GCGCCCGCTCATCACGCCCGCGCTGCTGCAGGAATGGCAGCCCGCGCCCGAGGCGGCGCAGACGCTGGTGGAAAGCAGCC
GCGTGGCCATCTCGCGCGTGCTGCACGGGCAGGACGACCGCCTCATCGTCGTGGTGGGGCCGTGCTCCATCCACGACCAT
GACCAGGCCATGGAGTACGCGCGCCTGTTGAAGGAGCAGGCGGATGCGTTGGCGCAGGACCTGCTCATCGTGATGCGCGT
GTATTTCGAGAAGCCCCGCACCACCGTGGGCTGGAAGGGCTACATCAACGACCCGCACCTGGACGGCAGCTTCGCCATCA
ACGAAGGCCTGGAGCGCGCCCGCGCATTGCTGCTGGACGTGCTGGCGCTGGGCCTGCCCGTGGGCACAGAGTTCCTGGAC
CTGCTGTCGCCGCAGTTCATCAGCGACCTGGTGAGCTGGGGCGCCATCGGCGCGCGCACCACCGAAAGCCAGAGCCACCG
GCAACTGGCCAGCGGCCTGTCCTGCCCCGTGGGCTTCAAGAACGGCACGGATGGCGGCGTGAAGGTGGCGGCCGACGCCA
TCCAGGCCGCGCAGGCACCGCATGCCTTCATGGGTATGACCAAGATGGGGCAGGCGGCGATCTTCGAGACGCGCGGCAAC
CACGACTGCCATGTGATCCTGCGCGGCGGCAAGGCCCCGAACTACGGCGCGGCCGACGTGCAGGCCGCCTGCGAGATGCT
GGGGAAGGCCGGCCAGCGCCCGCAGGTGATGATCGACCTGTCGCATGCCAACAGCAGCAAGCAGCACCGCCGCCAGATCG
ACGTGGCGCAGGACGTGGCCCAGCAGATCGCCGCGGGCGATGCACGCATCACCGGCGTGATGATCGAGAGCCACCTGCAG
GAGGGCCGCCAGGACATCGTGGACGGCCAGCCGCTCACACCCGGCGTGTCGGTCACCGACGCTTGCATCAGCTTCGCACA
GACCGTGCCGGTACTGCACCAGTTGGCTGCGGCCGTGCGCGAACGCCGCACGCGCGGCTGA

Upstream 100 bases:

>100_bases
ACAGGCGGTGTTACCTTCCTTCACCGCCACCTGCCGCCGGGGCAGGGCGCCGAACTCCCCGGACAGGCGCTCACGCGGGT
AGCGCGACAATCGGGGCACC

Downstream 100 bases:

>100_bases
CACGCTCCGGCGCCGTCGCGGCAGAAAAGAAGGAGGGCGCCCATGTACCATCAGTCACATCCGCCCGCCTTTTGGGCCAG
AAGCGTCCGCCATGTTCTTC

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MTLTERLASPLTTHDTTRIDDLRIKAVRPLITPALLQEWQPAPEAAQTLVESSRVAISRVLHGQDDRLIVVVGPCSIHDH
DQAMEYARLLKEQADALAQDLLIVMRVYFEKPRTTVGWKGYINDPHLDGSFAINEGLERARALLLDVLALGLPVGTEFLD
LLSPQFISDLVSWGAIGARTTESQSHRQLASGLSCPVGFKNGTDGGVKVAADAIQAAQAPHAFMGMTKMGQAAIFETRGN
HDCHVILRGGKAPNYGAADVQAACEMLGKAGQRPQVMIDLSHANSSKQHRRQIDVAQDVAQQIAAGDARITGVMIESHLQ
EGRQDIVDGQPLTPGVSVTDACISFAQTVPVLHQLAAAVRERRTRG

Sequences:

>Translated_366_residues
MTLTERLASPLTTHDTTRIDDLRIKAVRPLITPALLQEWQPAPEAAQTLVESSRVAISRVLHGQDDRLIVVVGPCSIHDH
DQAMEYARLLKEQADALAQDLLIVMRVYFEKPRTTVGWKGYINDPHLDGSFAINEGLERARALLLDVLALGLPVGTEFLD
LLSPQFISDLVSWGAIGARTTESQSHRQLASGLSCPVGFKNGTDGGVKVAADAIQAAQAPHAFMGMTKMGQAAIFETRGN
HDCHVILRGGKAPNYGAADVQAACEMLGKAGQRPQVMIDLSHANSSKQHRRQIDVAQDVAQQIAAGDARITGVMIESHLQ
EGRQDIVDGQPLTPGVSVTDACISFAQTVPVLHQLAAAVRERRTRG
>Mature_365_residues
TLTERLASPLTTHDTTRIDDLRIKAVRPLITPALLQEWQPAPEAAQTLVESSRVAISRVLHGQDDRLIVVVGPCSIHDHD
QAMEYARLLKEQADALAQDLLIVMRVYFEKPRTTVGWKGYINDPHLDGSFAINEGLERARALLLDVLALGLPVGTEFLDL
LSPQFISDLVSWGAIGARTTESQSHRQLASGLSCPVGFKNGTDGGVKVAADAIQAAQAPHAFMGMTKMGQAAIFETRGNH
DCHVILRGGKAPNYGAADVQAACEMLGKAGQRPQVMIDLSHANSSKQHRRQIDVAQDVAQQIAAGDARITGVMIESHLQE
GRQDIVDGQPLTPGVSVTDACISFAQTVPVLHQLAAAVRERRTRG

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786969, Length=344, Percent_Identity=61.3372093023256, Blast_Score=427, Evalue=1e-121,
Organism=Escherichia coli, GI1787996, Length=346, Percent_Identity=52.8901734104046, Blast_Score=376, Evalue=1e-105,
Organism=Escherichia coli, GI1788953, Length=341, Percent_Identity=53.0791788856305, Blast_Score=354, Evalue=4e-99,
Organism=Saccharomyces cerevisiae, GI6319726, Length=348, Percent_Identity=56.0344827586207, Blast_Score=357, Evalue=1e-99,
Organism=Saccharomyces cerevisiae, GI6320240, Length=357, Percent_Identity=49.2997198879552, Blast_Score=336, Evalue=4e-93,

Paralogues:

None

Copy number: 600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 39540; Mature: 39408

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLTERLASPLTTHDTTRIDDLRIKAVRPLITPALLQEWQPAPEAAQTLVESSRVAISRV
CCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
LHGQDDRLIVVVGPCSIHDHDQAMEYARLLKEQADALAQDLLIVMRVYFEKPRTTVGWKG
HCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
YINDPHLDGSFAINEGLERARALLLDVLALGLPVGTEFLDLLSPQFISDLVSWGAIGART
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCHHHHHHHHHHCCCCCCC
TESQSHRQLASGLSCPVGFKNGTDGGVKVAADAIQAAQAPHAFMGMTKMGQAAIFETRGN
CCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCHHEEECCCC
HDCHVILRGGKAPNYGAADVQAACEMLGKAGQRPQVMIDLSHANSSKQHRRQIDVAQDVA
CCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHH
QQIAAGDARITGVMIESHLQEGRQDIVDGQPLTPGVSVTDACISFAQTVPVLHQLAAAVR
HHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ERRTRG
HHHCCC
>Mature Secondary Structure 
TLTERLASPLTTHDTTRIDDLRIKAVRPLITPALLQEWQPAPEAAQTLVESSRVAISRV
CCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
LHGQDDRLIVVVGPCSIHDHDQAMEYARLLKEQADALAQDLLIVMRVYFEKPRTTVGWKG
HCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
YINDPHLDGSFAINEGLERARALLLDVLALGLPVGTEFLDLLSPQFISDLVSWGAIGART
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCHHHHHHHHHHCCCCCCC
TESQSHRQLASGLSCPVGFKNGTDGGVKVAADAIQAAQAPHAFMGMTKMGQAAIFETRGN
CCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCHHEEECCCC
HDCHVILRGGKAPNYGAADVQAACEMLGKAGQRPQVMIDLSHANSSKQHRRQIDVAQDVA
CCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHH
QQIAAGDARITGVMIESHLQEGRQDIVDGQPLTPGVSVTDACISFAQTVPVLHQLAAAVR
HHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ERRTRG
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]