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The map label for this gene is aatA [H]

Identifier: 222102910

GI number: 222102910

Start: 594894

End: 596108

Strand: Direct

Name: aatA [H]

Synonym: Avi_7660

Alternate gene names: 222102910

Gene position: 594894-596108 (Clockwise)

Preceding gene: 222102909

Following gene: 222102912

Centisome position: 94.16

GC content: 57.28

Gene sequence:

>1215_bases
ATGTCCATGCCCAAGCCAATGATTGCCGACCGTCTCAAGAATGTCGCGGTTTCCGCTTCCGCAGCCATGACGCAGCGTGC
CCGCGAACTTGCCGCCCAGGGCATTGACGTTGTATCCCTCTCATCTGGCGAGCCGGATTTTGCCACCCCCGCCCACGCCA
TTGAAGCTGCGCATGCGGCAGCGCTGGCTGGTGACACCAAATATCCGCCGCTGGATGGCACCGCTGCCTTGCGCGCTGCC
ATTTCCCGCAAATTCAAGCGCGAAAACAGCTTGGACTATGACCCAAGCCAGATTGTTGTCGCAGGTGGTGGCAAGCAGGT
GATTTTCAATGCGGTGATGGCCACCTGCAATCCCGGCGACGAAGTGGTGATCCCCACGCCATCGTGGATCAGCTATGCCG
ATATCGTACGCTTTGCAGGCGGTGTGCCGGTTCCCGTGGAATGCCCGCAGCAGAATGGTTTCAAGCTGCGCGCCGAAGAC
CTTGAGGCGGCCATTACGCCCAAAACCAAATGGCTGTTTTTGAACTTCCCCAACAATCCCACAGGTGCCGCCTGCTCGCG
CCAGGATATGGCCGCAATTGCCGAAGTGATGCTGCGTCATCCCGACGTCTGGATCATGACCGACGACATCTATGAACACC
TGATCTACGACGGCTTTGAATTTTGCACCATCGCCGAAGTTGAACCACGCCTCTATGACCGCGTGCTGACGGTAAACGGC
GCCTCAAAGGCCTATGCCATGACTGGTTGGCGTCTTGGCTATTGCGGTGGCCCGAAGGATCTCATCAAGGCAATCAGCAA
TGTCAACGGCCAGAACGCGGGCGGTACATCCACCATCACTCAGGCCGCTGCCATGGCTGTTCTGGATGGTCCGCAGGATC
TGTTGAAAGAACGCGCCAATATCTACAAGGGCCGTCGTGATTATGTGCTGTCGCGCCTTGCCGAGATTGATGGTCTGCGC
GCCCATAAGCCTGAAGGTGCGTTTTACATCTTCCCCAGCATCGCTGGCCTGATTGGCAAAACCACCAAGGGTGGCCGCAA
GATTGAAAACGACGCCGATTTCGTCTCGGCCCTGATTGATGAGCAGCATGTTGCGACCGTTCAAGGTGCGGCCTATGGCA
TGAGCCCCTTCTTCCGCATTTCCTATGCCACCAGCATGGAACGGCTTACAGCGGGCTGTGACCGGATTGCGCAATTCTGC
AAGGATATGAAGTAA

Upstream 100 bases:

>100_bases
AATTGAAGCCACGGGTGCTACCCTTGCCACTGCCCGCGACGTGATTGCCTGACATCACCCGATTTTGAAACCTTCACCAC
AACACTTGAAAGTCTAGACC

Downstream 100 bases:

>100_bases
TCTTGGCCATGTAGAAAATATTGCACCATGCATCCCAACGGATGCATGGCGCGCATAAACCGCTCTAATTCTTCAACTGC
CGCGTCAAACGCAGCAAAAT

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MSMPKPMIADRLKNVAVSASAAMTQRARELAAQGIDVVSLSSGEPDFATPAHAIEAAHAAALAGDTKYPPLDGTAALRAA
ISRKFKRENSLDYDPSQIVVAGGGKQVIFNAVMATCNPGDEVVIPTPSWISYADIVRFAGGVPVPVECPQQNGFKLRAED
LEAAITPKTKWLFLNFPNNPTGAACSRQDMAAIAEVMLRHPDVWIMTDDIYEHLIYDGFEFCTIAEVEPRLYDRVLTVNG
ASKAYAMTGWRLGYCGGPKDLIKAISNVNGQNAGGTSTITQAAAMAVLDGPQDLLKERANIYKGRRDYVLSRLAEIDGLR
AHKPEGAFYIFPSIAGLIGKTTKGGRKIENDADFVSALIDEQHVATVQGAAYGMSPFFRISYATSMERLTAGCDRIAQFC
KDMK

Sequences:

>Translated_404_residues
MSMPKPMIADRLKNVAVSASAAMTQRARELAAQGIDVVSLSSGEPDFATPAHAIEAAHAAALAGDTKYPPLDGTAALRAA
ISRKFKRENSLDYDPSQIVVAGGGKQVIFNAVMATCNPGDEVVIPTPSWISYADIVRFAGGVPVPVECPQQNGFKLRAED
LEAAITPKTKWLFLNFPNNPTGAACSRQDMAAIAEVMLRHPDVWIMTDDIYEHLIYDGFEFCTIAEVEPRLYDRVLTVNG
ASKAYAMTGWRLGYCGGPKDLIKAISNVNGQNAGGTSTITQAAAMAVLDGPQDLLKERANIYKGRRDYVLSRLAEIDGLR
AHKPEGAFYIFPSIAGLIGKTTKGGRKIENDADFVSALIDEQHVATVQGAAYGMSPFFRISYATSMERLTAGCDRIAQFC
KDMK
>Mature_403_residues
SMPKPMIADRLKNVAVSASAAMTQRARELAAQGIDVVSLSSGEPDFATPAHAIEAAHAAALAGDTKYPPLDGTAALRAAI
SRKFKRENSLDYDPSQIVVAGGGKQVIFNAVMATCNPGDEVVIPTPSWISYADIVRFAGGVPVPVECPQQNGFKLRAEDL
EAAITPKTKWLFLNFPNNPTGAACSRQDMAAIAEVMLRHPDVWIMTDDIYEHLIYDGFEFCTIAEVEPRLYDRVLTVNGA
SKAYAMTGWRLGYCGGPKDLIKAISNVNGQNAGGTSTITQAAAMAVLDGPQDLLKERANIYKGRRDYVLSRLAEIDGLRA
HKPEGAFYIFPSIAGLIGKTTKGGRKIENDADFVSALIDEQHVATVQGAAYGMSPFFRISYATSMERLTAGCDRIAQFCK
DMK

Specific function: Required for symbiotic nitrogen fixation [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=423, Percent_Identity=27.8959810874704, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI169881279, Length=423, Percent_Identity=27.8959810874704, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI56713256, Length=357, Percent_Identity=27.4509803921569, Blast_Score=138, Evalue=9e-33,
Organism=Homo sapiens, GI56713254, Length=354, Percent_Identity=27.4011299435028, Blast_Score=138, Evalue=9e-33,
Organism=Homo sapiens, GI169881281, Length=419, Percent_Identity=25.0596658711217, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI4507369, Length=382, Percent_Identity=24.0837696335079, Blast_Score=109, Evalue=5e-24,
Organism=Escherichia coli, GI1788722, Length=400, Percent_Identity=30.25, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1786816, Length=373, Percent_Identity=26.5415549597855, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1788627, Length=410, Percent_Identity=26.3414634146341, Blast_Score=129, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI71994476, Length=396, Percent_Identity=27.5252525252525, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI71994472, Length=396, Percent_Identity=27.5252525252525, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17567663, Length=376, Percent_Identity=25, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17567369, Length=317, Percent_Identity=25.5520504731861, Blast_Score=111, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6322401, Length=325, Percent_Identity=26.7692307692308, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI28573069, Length=392, Percent_Identity=25.765306122449, Blast_Score=137, Evalue=9e-33,
Organism=Drosophila melanogaster, GI24646114, Length=392, Percent_Identity=25.765306122449, Blast_Score=137, Evalue=9e-33,
Organism=Drosophila melanogaster, GI28573067, Length=392, Percent_Identity=25.765306122449, Blast_Score=137, Evalue=9e-33,
Organism=Drosophila melanogaster, GI28573065, Length=392, Percent_Identity=25.765306122449, Blast_Score=137, Evalue=9e-33,
Organism=Drosophila melanogaster, GI18859735, Length=319, Percent_Identity=23.1974921630094, Blast_Score=105, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43589; Mature: 43458

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMPKPMIADRLKNVAVSASAAMTQRARELAAQGIDVVSLSSGEPDFATPAHAIEAAHAA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHH
ALAGDTKYPPLDGTAALRAAISRKFKRENSLDYDPSQIVVAGGGKQVIFNAVMATCNPGD
HHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCC
EVVIPTPSWISYADIVRFAGGVPVPVECPQQNGFKLRAEDLEAAITPKTKWLFLNFPNNP
EEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEHHHCCCEECCCEEEEEEECCCCC
TGAACSRQDMAAIAEVMLRHPDVWIMTDDIYEHLIYDGFEFCTIAEVEPRLYDRVLTVNG
CCCCCCHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHCCCCEEEEECCCHHHHHEEEEECC
ASKAYAMTGWRLGYCGGPKDLIKAISNVNGQNAGGTSTITQAAAMAVLDGPQDLLKERAN
CCCEEEECCCEEEECCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHH
IYKGRRDYVLSRLAEIDGLRAHKPEGAFYIFPSIAGLIGKTTKGGRKIENDADFVSALID
HHCCHHHHHHHHHHHHCCCCCCCCCCCEEECCHHHHHHCCCCCCCCCCCCHHHHHHHHHH
EQHVATVQGAAYGMSPFFRISYATSMERLTAGCDRIAQFCKDMK
HHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SMPKPMIADRLKNVAVSASAAMTQRARELAAQGIDVVSLSSGEPDFATPAHAIEAAHAA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHH
ALAGDTKYPPLDGTAALRAAISRKFKRENSLDYDPSQIVVAGGGKQVIFNAVMATCNPGD
HHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCC
EVVIPTPSWISYADIVRFAGGVPVPVECPQQNGFKLRAEDLEAAITPKTKWLFLNFPNNP
EEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEHHHCCCEECCCEEEEEEECCCCC
TGAACSRQDMAAIAEVMLRHPDVWIMTDDIYEHLIYDGFEFCTIAEVEPRLYDRVLTVNG
CCCCCCHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHCCCCEEEEECCCHHHHHEEEEECC
ASKAYAMTGWRLGYCGGPKDLIKAISNVNGQNAGGTSTITQAAAMAVLDGPQDLLKERAN
CCCEEEECCCEEEECCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHH
IYKGRRDYVLSRLAEIDGLRAHKPEGAFYIFPSIAGLIGKTTKGGRKIENDADFVSALID
HHCCHHHHHHHHHHHHCCCCCCCCCCCEEECCHHHHHHCCCCCCCCCCCCHHHHHHHHHH
EQHVATVQGAAYGMSPFFRISYATSMERLTAGCDRIAQFCKDMK
HHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2019560; 8096210; 11481430 [H]