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The map label for this gene is acoR [H]

Identifier: 222102899

GI number: 222102899

Start: 582859

End: 584745

Strand: Direct

Name: acoR [H]

Synonym: Avi_7648

Alternate gene names: 222102899

Gene position: 582859-584745 (Clockwise)

Preceding gene: 222102898

Following gene: 222102900

Centisome position: 92.26

GC content: 62.32

Gene sequence:

>1887_bases
ATGGGTTTTGCCGATCACGTCAAGGAAATCGAGCGCGTCGGGCAGGGAAGCAATACCGGCCGCGACGCCATTGTCGTGGA
ATCCTGGCGGCGTTGCCTGGAGACCTACCAGCTCGACCCGGCGCAAGCGCGTGAGGCGGTTATCGTCTCGCAAACACGCC
TGCGCGAACATCGTCAGCAGGCGGAGGACCTCGTACACATCGCACGCTCTGGGCTGGAGCGGCTCTACCGGCAGGTTGCC
GAGCAGAATTATGTTCTTCTCCTCTCCGACCGGCAGGGCGTAACCGTCGAATTTCTCGGTGATCCCTCCTTCAACAACAA
CTTGCGAAAGGCCGGGCTCTATCTCGGCTCGGAATGGTCCGAGCCCCGCGCTGGCACGTGCGCTGTTGGCGCCTGCCTGG
CCACCGGCGAGGCTCTGACGATCCATCAGACCGACCATTTTGACATCACCCATACACCACTCTCCTGCACCGCTGCACCG
ATCTATGACACGCAAGGCGCGTTGGCAGCGGTCCTCGATATTTCGCTGCTGAGCTCACCCATCTTAAAGACGAGCCAGAA
TATGGCACGTCATCTTGTCTCCTCGACCGTGCGGCGCATCGAGCTCGCCAATCTCATGGCGAACAGTCGACACGACCTGG
TGCTGCGCTTTGCTGGCGCGCCGGAATTTCTCGATGTTGATCCGGAAGCGGCGATTTCCGTCGATGGCGCCGGACGCATC
ACCGGCATGACGCATGGCGGCGCGCGGCTTCTCGCTGCCTCGCGTGGAATTGACTGGCGACAGCCCGAGCTTGTGCTTGG
CCAGCCGGTCGCGGATTTTTTCGAGGCAGGCTTGGACGAGCTCGCTTCGCTGACCCGCGCCAGCCTGCCGCAAGACCGGC
GGATTGCCGTGCGCGATGGGTCGGTCCTCTTTGCCCATGCGATCGAGCCGCAACAGCGCGTGGCCGGGACGCCGCTCGTC
CGAGCTCTTCGGTCGCCGCCAGCCATGAACCTGCTCGGCGGCAGTGTCGAAATCATGGACAGCCTTCGCCGCAAGATCGC
CAAGCTCGCACCGAGCGCACTGCCGATCCTGCTTCAGGGCGAGACCGGAACCGGCAAGGAATATCTGGCACGCATCATCC
ACGAGGTGAGCGGGTTGTCAGGCCGCTTCGTTGCGGTCAATTGCGCAGCAATCCCTGAACAGCTGATCGAAAGCGAATTG
TTCGGCTATGCGCCAGGCGCCTTCACCGGCGCCCTTGTCAAGGGACGAAAGGGGTTGGTCGAGGAAGCGGTGGGCGGAAC
CCTGTTCCTCGACGAAATCGGCGACATGCCATACGCCGCGCAAAGCAGGTTGCTCAGGGTTCTGGCCGAGGGTGAGGTGT
TGCCGGTCGGCGGTTCGGTGGCGCGCAAGGTGGAGTTTCGCGTCGTGTCTGCGTCGCATCGGTCTTTGGCCGACATGGTC
GCAACCGGCGCATTCCGGCAAGACCTCTATTACCGGCTGAATGCCGCCGTACTATCCCTTCCACGGCTTTGTGAGCGCGG
CGACTTGCCATGGCTCCTCGACAAGTTGCTCGAAAAACATGCTCCGGTGAACCGATCGCTCAGGCTTTCAAACACTGCCC
GCCTTTTGATCCTCAATCATCGCTGGCCAGGCAATATCCGCGAGCTGGACAATGCGATCGCCTTCGCCGCAGCCCTGTGC
GACGATGGGCTGATTGAGGTAACGGACCTTCCAGAACAGCTGGCTGCCAACGTGCAGCTGCCTGGCGACGACAGCCCTGA
AGCCGAACTTCGCGCGGTGCTCGCCGCTTGCCATGGCAATGTTTCCGAGGCGGCGCGCCGCCTCGGTATTGATCGCACCA
CAATGCATCGCCGTATGCGCAGGTTCGGCATAGACAGGCCGCATTGA

Upstream 100 bases:

>100_bases
TGACCGACAAGATGTCTCGAAGCATTAGGCGCTTCTGGCAATTGGGGCTATGATCTCCTTAAAGATCACGGGAGGCGGCT
TTTCAAGAGCCGGTGATTTC

Downstream 100 bases:

>100_bases
GCATCCGGACTGTGGCATACGCCACACCTGTCGCGCCACAGCTGTGGCGTAGCGAAACCTGCCCCGCCTCGAAAACTGAA
TAATTCCAGTCCTTCGCCCT

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 628; Mature: 627

Protein sequence:

>628_residues
MGFADHVKEIERVGQGSNTGRDAIVVESWRRCLETYQLDPAQAREAVIVSQTRLREHRQQAEDLVHIARSGLERLYRQVA
EQNYVLLLSDRQGVTVEFLGDPSFNNNLRKAGLYLGSEWSEPRAGTCAVGACLATGEALTIHQTDHFDITHTPLSCTAAP
IYDTQGALAAVLDISLLSSPILKTSQNMARHLVSSTVRRIELANLMANSRHDLVLRFAGAPEFLDVDPEAAISVDGAGRI
TGMTHGGARLLAASRGIDWRQPELVLGQPVADFFEAGLDELASLTRASLPQDRRIAVRDGSVLFAHAIEPQQRVAGTPLV
RALRSPPAMNLLGGSVEIMDSLRRKIAKLAPSALPILLQGETGTGKEYLARIIHEVSGLSGRFVAVNCAAIPEQLIESEL
FGYAPGAFTGALVKGRKGLVEEAVGGTLFLDEIGDMPYAAQSRLLRVLAEGEVLPVGGSVARKVEFRVVSASHRSLADMV
ATGAFRQDLYYRLNAAVLSLPRLCERGDLPWLLDKLLEKHAPVNRSLRLSNTARLLILNHRWPGNIRELDNAIAFAAALC
DDGLIEVTDLPEQLAANVQLPGDDSPEAELRAVLAACHGNVSEAARRLGIDRTTMHRRMRRFGIDRPH

Sequences:

>Translated_628_residues
MGFADHVKEIERVGQGSNTGRDAIVVESWRRCLETYQLDPAQAREAVIVSQTRLREHRQQAEDLVHIARSGLERLYRQVA
EQNYVLLLSDRQGVTVEFLGDPSFNNNLRKAGLYLGSEWSEPRAGTCAVGACLATGEALTIHQTDHFDITHTPLSCTAAP
IYDTQGALAAVLDISLLSSPILKTSQNMARHLVSSTVRRIELANLMANSRHDLVLRFAGAPEFLDVDPEAAISVDGAGRI
TGMTHGGARLLAASRGIDWRQPELVLGQPVADFFEAGLDELASLTRASLPQDRRIAVRDGSVLFAHAIEPQQRVAGTPLV
RALRSPPAMNLLGGSVEIMDSLRRKIAKLAPSALPILLQGETGTGKEYLARIIHEVSGLSGRFVAVNCAAIPEQLIESEL
FGYAPGAFTGALVKGRKGLVEEAVGGTLFLDEIGDMPYAAQSRLLRVLAEGEVLPVGGSVARKVEFRVVSASHRSLADMV
ATGAFRQDLYYRLNAAVLSLPRLCERGDLPWLLDKLLEKHAPVNRSLRLSNTARLLILNHRWPGNIRELDNAIAFAAALC
DDGLIEVTDLPEQLAANVQLPGDDSPEAELRAVLAACHGNVSEAARRLGIDRTTMHRRMRRFGIDRPH
>Mature_627_residues
GFADHVKEIERVGQGSNTGRDAIVVESWRRCLETYQLDPAQAREAVIVSQTRLREHRQQAEDLVHIARSGLERLYRQVAE
QNYVLLLSDRQGVTVEFLGDPSFNNNLRKAGLYLGSEWSEPRAGTCAVGACLATGEALTIHQTDHFDITHTPLSCTAAPI
YDTQGALAAVLDISLLSSPILKTSQNMARHLVSSTVRRIELANLMANSRHDLVLRFAGAPEFLDVDPEAAISVDGAGRIT
GMTHGGARLLAASRGIDWRQPELVLGQPVADFFEAGLDELASLTRASLPQDRRIAVRDGSVLFAHAIEPQQRVAGTPLVR
ALRSPPAMNLLGGSVEIMDSLRRKIAKLAPSALPILLQGETGTGKEYLARIIHEVSGLSGRFVAVNCAAIPEQLIESELF
GYAPGAFTGALVKGRKGLVEEAVGGTLFLDEIGDMPYAAQSRLLRVLAEGEVLPVGGSVARKVEFRVVSASHRSLADMVA
TGAFRQDLYYRLNAAVLSLPRLCERGDLPWLLDKLLEKHAPVNRSLRLSNTARLLILNHRWPGNIRELDNAIAFAAALCD
DGLIEVTDLPEQLAANVQLPGDDSPEAELRAVLAACHGNVSEAARRLGIDRTTMHRRMRRFGIDRPH

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789233, Length=321, Percent_Identity=39.8753894080997, Blast_Score=224, Evalue=2e-59,
Organism=Escherichia coli, GI1788905, Length=294, Percent_Identity=43.1972789115646, Blast_Score=213, Evalue=3e-56,
Organism=Escherichia coli, GI1790437, Length=300, Percent_Identity=44.6666666666667, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1788550, Length=316, Percent_Identity=40.5063291139241, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1789087, Length=308, Percent_Identity=42.2077922077922, Blast_Score=189, Evalue=7e-49,
Organism=Escherichia coli, GI1786524, Length=324, Percent_Identity=41.358024691358, Blast_Score=187, Evalue=2e-48,
Organism=Escherichia coli, GI1790299, Length=341, Percent_Identity=36.6568914956012, Blast_Score=186, Evalue=4e-48,
Organism=Escherichia coli, GI87082117, Length=312, Percent_Identity=41.3461538461538, Blast_Score=183, Evalue=3e-47,
Organism=Escherichia coli, GI87082152, Length=310, Percent_Identity=39.6774193548387, Blast_Score=180, Evalue=3e-46,
Organism=Escherichia coli, GI1787583, Length=307, Percent_Identity=36.1563517915309, Blast_Score=169, Evalue=7e-43,
Organism=Escherichia coli, GI87081872, Length=231, Percent_Identity=43.2900432900433, Blast_Score=159, Evalue=6e-40,
Organism=Escherichia coli, GI87081858, Length=655, Percent_Identity=26.7175572519084, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1789828, Length=270, Percent_Identity=37.037037037037, Blast_Score=140, Evalue=3e-34,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 68360; Mature: 68229

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFADHVKEIERVGQGSNTGRDAIVVESWRRCLETYQLDPAQAREAVIVSQTRLREHRQQ
CCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
AEDLVHIARSGLERLYRQVAEQNYVLLLSDRQGVTVEFLGDPSFNNNLRKAGLYLGSEWS
HHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEECCCCCCCCHHHHHCEECCCCC
EPRAGTCAVGACLATGEALTIHQTDHFDITHTPLSCTAAPIYDTQGALAAVLDISLLSSP
CCCCCHHHHHHHHHCCCEEEEEECCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
ILKTSQNMARHLVSSTVRRIELANLMANSRHDLVLRFAGAPEFLDVDPEAAISVDGAGRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEEECCCCCE
TGMTHGGARLLAASRGIDWRQPELVLGQPVADFFEAGLDELASLTRASLPQDRRIAVRDG
EEECCCCCEEEEHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECC
SVLFAHAIEPQQRVAGTPLVRALRSPPAMNLLGGSVEIMDSLRRKIAKLAPSALPILLQG
CEEEEECCCHHHHHCCCHHHHHHCCCCCCHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEC
ETGTGKEYLARIIHEVSGLSGRFVAVNCAAIPEQLIESELFGYAPGAFTGALVKGRKGLV
CCCCCHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHH
EEAVGGTLFLDEIGDMPYAAQSRLLRVLAEGEVLPVGGSVARKVEFRVVSASHRSLADMV
HHHCCCEEEEHHHCCCCHHHHHHHHHHHHCCCEEECCCHHHHEEEEEEECCCHHHHHHHH
ATGAFRQDLYYRLNAAVLSLPRLCERGDLPWLLDKLLEKHAPVNRSLRLSNTARLLILNH
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEECCCEEEEEEEC
RWPGNIRELDNAIAFAAALCDDGLIEVTDLPEQLAANVQLPGDDSPEAELRAVLAACHGN
CCCCCHHHHHHHHHHHHHHHCCCCEEECCCHHHHHCCCCCCCCCCCHHHHHHHHHHHCCC
VSEAARRLGIDRTTMHRRMRRFGIDRPH
HHHHHHHHCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
GFADHVKEIERVGQGSNTGRDAIVVESWRRCLETYQLDPAQAREAVIVSQTRLREHRQQ
CHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
AEDLVHIARSGLERLYRQVAEQNYVLLLSDRQGVTVEFLGDPSFNNNLRKAGLYLGSEWS
HHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEECCCCCCCCHHHHHCEECCCCC
EPRAGTCAVGACLATGEALTIHQTDHFDITHTPLSCTAAPIYDTQGALAAVLDISLLSSP
CCCCCHHHHHHHHHCCCEEEEEECCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
ILKTSQNMARHLVSSTVRRIELANLMANSRHDLVLRFAGAPEFLDVDPEAAISVDGAGRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEEECCCCCE
TGMTHGGARLLAASRGIDWRQPELVLGQPVADFFEAGLDELASLTRASLPQDRRIAVRDG
EEECCCCCEEEEHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECC
SVLFAHAIEPQQRVAGTPLVRALRSPPAMNLLGGSVEIMDSLRRKIAKLAPSALPILLQG
CEEEEECCCHHHHHCCCHHHHHHCCCCCCHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEC
ETGTGKEYLARIIHEVSGLSGRFVAVNCAAIPEQLIESELFGYAPGAFTGALVKGRKGLV
CCCCCHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHH
EEAVGGTLFLDEIGDMPYAAQSRLLRVLAEGEVLPVGGSVARKVEFRVVSASHRSLADMV
HHHCCCEEEEHHHCCCCHHHHHHHHHHHHCCCEEECCCHHHHEEEEEEECCCHHHHHHHH
ATGAFRQDLYYRLNAAVLSLPRLCERGDLPWLLDKLLEKHAPVNRSLRLSNTARLLILNH
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEECCCEEEEEEEC
RWPGNIRELDNAIAFAAALCDDGLIEVTDLPEQLAANVQLPGDDSPEAELRAVLAACHGN
CCCCCHHHHHHHHHHHHHHHCCCCEEECCCHHHHHCCCCCCCCCCCHHHHHHHHHHHCCC
VSEAARRLGIDRTTMHRRMRRFGIDRPH
HHHHHHHHCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]