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The map label for this gene is mcpA [H]

Identifier: 222102896

GI number: 222102896

Start: 577013

End: 578740

Strand: Reverse

Name: mcpA [H]

Synonym: Avi_7643

Alternate gene names: 222102896

Gene position: 578740-577013 (Counterclockwise)

Preceding gene: 222102902

Following gene: 222102894

Centisome position: 91.61

GC content: 52.37

Gene sequence:

>1728_bases
ATGGGATTGTTGTCAATTGTATTCGGAAGCGACATCAAAGCTATTTTCGATGCCATAAATCGGTCTCAAGGCGTCATTGA
ATTCGACATCCAGGGCAATATTCTTGATGCGAATGACAATTTCTGCAAGACGCTTGGATATGCAAAATCAGATATCATTG
GCAAACACCATCGGATCTTTCTCGATCCTGAAGAGGTGAAGACTAAAGCCTATGCCGATTTCTGGGCAAAACTCGTTTCC
GGCCAGTTCGACCAGCGCCAATATAAGCGGTTCACCAAATCGGGCGACCCCATCTGGATCGAAGCCTCTTACAATCCGGT
TTTTCGCGGGGGTAAGCCTTACAAAATTGTAAAAATTGCCACGGACATTACGGCGTCCACAAACAAAGCTATGGATGGCG
ACGGCAAGATGGAAGCGTTGTTGCGTTCTCAGGCCGTTATCGAGTTCACACCGACTGGCCAGATTTTGACTGCCAACGAG
AATTTCTGCAAGGCGATGAACTACGACCTCAGCGAGATCATTGGCAAAAATCATTCGATGTTTTGTGAACAAGCTTACAT
CGCGTCCCCCGATTACAAAGAGTTCTGGCGCAAGCTTGGAGCAGATGAGTTCCAGAGCGACGAGTTCTTGCGGATCGGGA
AAGGTGGCAAGAAAGTCTATATTCAGGCCACTTATAACCCCATCACAGATGAAAAGGGAAAGGTCGTCAAGGTTGTGAAA
TTCGCGATCGATGTCACCGGCCGCGTCAACGCCATTGCTGCGATTGGTGCAGGTCTTGAGCGCTTGTCCGACTGCAATAT
CCGAATGACGATTGATGAGCCGTTCATTCCAACCTTCGAGCACTTGCGTAAAGACTTCAACATGTCCATTGGCAAATTCC
AGGAAACCCTGGCGCAGGTGCTGGCGGAAACGGCGGCGGTTTCCGCCAATAGTCATGATATGCTCAAGGGATCGACCAGC
CTGGCAAAACGCTCGGAGCAACAGGCTGCCGCACTGGAGCAGACTTCTGCGGCATTGGAAGAAATAACCGCGACGGTGAG
AGAATCCAGTGCGCGTTCCAAAGATACTCGAAACTTGGTGCGCGACGCTCGTCAGGCCGCAACCGAGTCCGTAAAGGTCG
TTAACTTCACCGTCGCCGCCATGAGCCGCATCGAGGGCGCTTCGAAGGAAATCAGTAATATCATCACTGTTATCGATGAA
ATTGCCTTCCAGACCAACCTTTTAGCCCTGAATGCAGGCGTCGAAGCAGCCCGCGCTGGTGAAAGTGGCAAGGGCTTTGC
GGTCGTGGCCCAGGAGGTCCGTGAGTTGGCTCAACGCTCCGCCAAGGCCGCCAAGGAAATTTCGGAATTGATCGCTAAAT
CGACCAATGAAGTGAAGGACGGTGTACGTCTGGTCGGGGAAACCGGCAGTGCGCTGAACCGGATCGAGTCCTTCGTGCAA
TCTATCGATGTTAATATTGAAGCCATTTCCACGGCAGCGTCGGAGCAATCCACTAGCCTCACGGAAATCAGCACTGCGGT
CAACGCCTTAGACCAGATGACACAACAGAACGCGGGAATGGTCAGCGGCATGAATGCCATCAGCGAAGCACTTTCCAGTG
GCGCGGCTAAACTGAGCGAACTGGCAAACCGCTTCCAGCTCAACAGGCGCAGTGCCATCCGCGAGCCGGGAAGTTCCGCT
GCAATGCGTGACAACGACAGGCGGGAAAGCAATCGCTCGGCGGCCTGA

Upstream 100 bases:

>100_bases
GCAAAAATAAAAAAACGATCTTTTGGTATTTATTTTGTAATATTTATTATTCCTAAATAATATATATTATAATGTTCCGC
TATCAATAGGAGACGGCGCT

Downstream 100 bases:

>100_bases
CCGACAGACTATTTATGACCTGTATTAACGCTCAGTCAGCGGCGTCAGAATGGTCCAAGTATCAACGCTCGTGGATCAAA
AATTGAACACGCCGGACGCC

Product: sensory methylation accepting chemotaxis protein

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 575; Mature: 574

Protein sequence:

>575_residues
MGLLSIVFGSDIKAIFDAINRSQGVIEFDIQGNILDANDNFCKTLGYAKSDIIGKHHRIFLDPEEVKTKAYADFWAKLVS
GQFDQRQYKRFTKSGDPIWIEASYNPVFRGGKPYKIVKIATDITASTNKAMDGDGKMEALLRSQAVIEFTPTGQILTANE
NFCKAMNYDLSEIIGKNHSMFCEQAYIASPDYKEFWRKLGADEFQSDEFLRIGKGGKKVYIQATYNPITDEKGKVVKVVK
FAIDVTGRVNAIAAIGAGLERLSDCNIRMTIDEPFIPTFEHLRKDFNMSIGKFQETLAQVLAETAAVSANSHDMLKGSTS
LAKRSEQQAAALEQTSAALEEITATVRESSARSKDTRNLVRDARQAATESVKVVNFTVAAMSRIEGASKEISNIITVIDE
IAFQTNLLALNAGVEAARAGESGKGFAVVAQEVRELAQRSAKAAKEISELIAKSTNEVKDGVRLVGETGSALNRIESFVQ
SIDVNIEAISTAASEQSTSLTEISTAVNALDQMTQQNAGMVSGMNAISEALSSGAAKLSELANRFQLNRRSAIREPGSSA
AMRDNDRRESNRSAA

Sequences:

>Translated_575_residues
MGLLSIVFGSDIKAIFDAINRSQGVIEFDIQGNILDANDNFCKTLGYAKSDIIGKHHRIFLDPEEVKTKAYADFWAKLVS
GQFDQRQYKRFTKSGDPIWIEASYNPVFRGGKPYKIVKIATDITASTNKAMDGDGKMEALLRSQAVIEFTPTGQILTANE
NFCKAMNYDLSEIIGKNHSMFCEQAYIASPDYKEFWRKLGADEFQSDEFLRIGKGGKKVYIQATYNPITDEKGKVVKVVK
FAIDVTGRVNAIAAIGAGLERLSDCNIRMTIDEPFIPTFEHLRKDFNMSIGKFQETLAQVLAETAAVSANSHDMLKGSTS
LAKRSEQQAAALEQTSAALEEITATVRESSARSKDTRNLVRDARQAATESVKVVNFTVAAMSRIEGASKEISNIITVIDE
IAFQTNLLALNAGVEAARAGESGKGFAVVAQEVRELAQRSAKAAKEISELIAKSTNEVKDGVRLVGETGSALNRIESFVQ
SIDVNIEAISTAASEQSTSLTEISTAVNALDQMTQQNAGMVSGMNAISEALSSGAAKLSELANRFQLNRRSAIREPGSSA
AMRDNDRRESNRSAA
>Mature_574_residues
GLLSIVFGSDIKAIFDAINRSQGVIEFDIQGNILDANDNFCKTLGYAKSDIIGKHHRIFLDPEEVKTKAYADFWAKLVSG
QFDQRQYKRFTKSGDPIWIEASYNPVFRGGKPYKIVKIATDITASTNKAMDGDGKMEALLRSQAVIEFTPTGQILTANEN
FCKAMNYDLSEIIGKNHSMFCEQAYIASPDYKEFWRKLGADEFQSDEFLRIGKGGKKVYIQATYNPITDEKGKVVKVVKF
AIDVTGRVNAIAAIGAGLERLSDCNIRMTIDEPFIPTFEHLRKDFNMSIGKFQETLAQVLAETAAVSANSHDMLKGSTSL
AKRSEQQAAALEQTSAALEEITATVRESSARSKDTRNLVRDARQAATESVKVVNFTVAAMSRIEGASKEISNIITVIDEI
AFQTNLLALNAGVEAARAGESGKGFAVVAQEVRELAQRSAKAAKEISELIAKSTNEVKDGVRLVGETGSALNRIESFVQS
IDVNIEAISTAASEQSTSLTEISTAVNALDQMTQQNAGMVSGMNAISEALSSGAAKLSELANRFQLNRRSAIREPGSSAA
MRDNDRRESNRSAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=306, Percent_Identity=37.5816993464052, Blast_Score=185, Evalue=8e-48,
Organism=Escherichia coli, GI1788195, Length=294, Percent_Identity=39.7959183673469, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI2367378, Length=227, Percent_Identity=43.6123348017621, Blast_Score=169, Evalue=7e-43,
Organism=Escherichia coli, GI1788194, Length=243, Percent_Identity=41.9753086419753, Blast_Score=166, Evalue=4e-42,
Organism=Escherichia coli, GI1789453, Length=241, Percent_Identity=36.0995850622407, Blast_Score=137, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 62646; Mature: 62515

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLLSIVFGSDIKAIFDAINRSQGVIEFDIQGNILDANDNFCKTLGYAKSDIIGKHHRIF
CCCEEEECCCCHHHHHHHHCCCCCEEEEEECCCEECCCCCHHHHHCCHHHHHCCCCCEEE
LDPEEVKTKAYADFWAKLVSGQFDQRQYKRFTKSGDPIWIEASYNPVFRGGKPYKIVKIA
ECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEEEEEE
TDITASTNKAMDGDGKMEALLRSQAVIEFTPTGQILTANENFCKAMNYDLSEIIGKNHSM
ECCCCCCCCCCCCCHHHHHHHHCCCEEEECCCCCEEECCCHHHHHCCCCHHHHHCCCCCH
FCEQAYIASPDYKEFWRKLGADEFQSDEFLRIGKGGKKVYIQATYNPITDEKGKVVKVVK
HHHHHHCCCCCHHHHHHHCCCCCCCCCCEEEECCCCCEEEEEEECCCCCCCCCCEEEEHH
FAIDVTGRVNAIAAIGAGLERLSDCNIRMTIDEPFIPTFEHLRKDFNMSIGKFQETLAQV
HHHHCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHH
LAETAAVSANSHDMLKGSTSLAKRSEQQAAALEQTSAALEEITATVRESSARSKDTRNLV
HHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
RDARQAATESVKVVNFTVAAMSRIEGASKEISNIITVIDEIAFQTNLLALNAGVEAARAG
HHHHHHHHCCCHHEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHCC
ESGKGFAVVAQEVRELAQRSAKAAKEISELIAKSTNEVKDGVRLVGETGSALNRIESFVQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHH
SIDVNIEAISTAASEQSTSLTEISTAVNALDQMTQQNAGMVSGMNAISEALSSGAAKLSE
HHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
LANRFQLNRRSAIREPGSSAAMRDNDRRESNRSAA
HHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCCC
>Mature Secondary Structure 
GLLSIVFGSDIKAIFDAINRSQGVIEFDIQGNILDANDNFCKTLGYAKSDIIGKHHRIF
CCEEEECCCCHHHHHHHHCCCCCEEEEEECCCEECCCCCHHHHHCCHHHHHCCCCCEEE
LDPEEVKTKAYADFWAKLVSGQFDQRQYKRFTKSGDPIWIEASYNPVFRGGKPYKIVKIA
ECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEEEEEE
TDITASTNKAMDGDGKMEALLRSQAVIEFTPTGQILTANENFCKAMNYDLSEIIGKNHSM
ECCCCCCCCCCCCCHHHHHHHHCCCEEEECCCCCEEECCCHHHHHCCCCHHHHHCCCCCH
FCEQAYIASPDYKEFWRKLGADEFQSDEFLRIGKGGKKVYIQATYNPITDEKGKVVKVVK
HHHHHHCCCCCHHHHHHHCCCCCCCCCCEEEECCCCCEEEEEEECCCCCCCCCCEEEEHH
FAIDVTGRVNAIAAIGAGLERLSDCNIRMTIDEPFIPTFEHLRKDFNMSIGKFQETLAQV
HHHHCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHH
LAETAAVSANSHDMLKGSTSLAKRSEQQAAALEQTSAALEEITATVRESSARSKDTRNLV
HHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
RDARQAATESVKVVNFTVAAMSRIEGASKEISNIITVIDEIAFQTNLLALNAGVEAARAG
HHHHHHHHCCCHHEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHCC
ESGKGFAVVAQEVRELAQRSAKAAKEISELIAKSTNEVKDGVRLVGETGSALNRIESFVQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHH
SIDVNIEAISTAASEQSTSLTEISTAVNALDQMTQQNAGMVSGMNAISEALSSGAAKLSE
HHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
LANRFQLNRRSAIREPGSSAAMRDNDRRESNRSAA
HHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]