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The map label for this gene is dppC [H]

Identifier: 222102812

GI number: 222102812

Start: 478058

End: 478978

Strand: Direct

Name: dppC [H]

Synonym: Avi_7532

Alternate gene names: 222102812

Gene position: 478058-478978 (Clockwise)

Preceding gene: 222102811

Following gene: 222102813

Centisome position: 75.67

GC content: 57.33

Gene sequence:

>921_bases
ATGAGCACGCCCGGCACTCCTTCACCATCAATGGCAGATAAGAACAGCGACCTGAGCGCGATTGTGCGAGCCAATATGCC
ATGGTCGGCCAGATTGCGGCTGCCGGGTGCAAGCCCCTTTGAGCTGGTTGCGCTCGGCTTTCTGATACTGCTGGTGCTGA
CCGCGATTTTTGTCAATTTCATTCCGGGACTTGTCAGCCCCAGATTCCCCTACGGCGATTTTTCCCAGCCGCCAGAATGG
TCATTAAACGGGCTTCTGGGAACCGATGATATTGGCCGCAGCATCCTGTCGCGTGTGCTCTATGGGGCGCGGGCATCGTT
GATGATTGTTGGCGTCGCCACCTGTATTTCAGTGTTCGCTGGCCTGTTGTTGGGCATGCTCGCAGGCTTCTATCGCGGCA
TTTTTGAGCGCATGGTTGATCTCTACGCCAATACAATGTCGGCTCTGCCGTCCATTCTGGTGGTATTGGCCTTCGTGACG
GCCACAGGACCCTCGGTGCTGACGATTATGCTCACCCTTGGCATTCTCGATATCGGCACTTACGCCCGTGTTGCCAAGGC
GGGTGTGATTTCCCAGAGCAACCGGGACTATGTTCTCGCCGCCCGCGCCATGGGGGCAAGAGATAGCCGGATTCTGCTGA
AGGAAATCCTGCCCAATCTGGTCCCGGCTCTCACCGCTGTCATGCCCACCTTGATGGCAGGCCTGATTATCACCGAAGGA
TCATTGAGCTTTCTCGGCTATGGCATTCCGGCCCCGGCCCCCAGTTGGGGCGGCATGATTGCCAGCTCCACCGATCTGCT
AAGCCGCTTTCCTCTGCTGATCCTTGGGCCGGTAATGGCCATTATTCTAACGGTCTATGCGTTCAACACCGTGGGGGATT
ATTTCGCCCAGCGTCTCAACAGCCGCGAGAGGGAGAGCTGA

Upstream 100 bases:

>100_bases
TGGTGCAGGCGATTTTGTCGCTCACTGTCGTGGTCTTCGTCACCATCTTCATGCTGGTGGATATCGGCTATGCCATCATC
GATCCACGGGTTAATGTCAC

Downstream 100 bases:

>100_bases
TATGGCCAGTGACATCAGCCAACCTCCTATCCTGTCGTGCGAGCGCATGTCCTGCACAATTGCGGCAAAACCTGCCCCTT
TGCAGGTGCTGCACGATATT

Product: ABC transporter membrane spanning protein (dipeptide)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MSTPGTPSPSMADKNSDLSAIVRANMPWSARLRLPGASPFELVALGFLILLVLTAIFVNFIPGLVSPRFPYGDFSQPPEW
SLNGLLGTDDIGRSILSRVLYGARASLMIVGVATCISVFAGLLLGMLAGFYRGIFERMVDLYANTMSALPSILVVLAFVT
ATGPSVLTIMLTLGILDIGTYARVAKAGVISQSNRDYVLAARAMGARDSRILLKEILPNLVPALTAVMPTLMAGLIITEG
SLSFLGYGIPAPAPSWGGMIASSTDLLSRFPLLILGPVMAIILTVYAFNTVGDYFAQRLNSRERES

Sequences:

>Translated_306_residues
MSTPGTPSPSMADKNSDLSAIVRANMPWSARLRLPGASPFELVALGFLILLVLTAIFVNFIPGLVSPRFPYGDFSQPPEW
SLNGLLGTDDIGRSILSRVLYGARASLMIVGVATCISVFAGLLLGMLAGFYRGIFERMVDLYANTMSALPSILVVLAFVT
ATGPSVLTIMLTLGILDIGTYARVAKAGVISQSNRDYVLAARAMGARDSRILLKEILPNLVPALTAVMPTLMAGLIITEG
SLSFLGYGIPAPAPSWGGMIASSTDLLSRFPLLILGPVMAIILTVYAFNTVGDYFAQRLNSRERES
>Mature_305_residues
STPGTPSPSMADKNSDLSAIVRANMPWSARLRLPGASPFELVALGFLILLVLTAIFVNFIPGLVSPRFPYGDFSQPPEWS
LNGLLGTDDIGRSILSRVLYGARASLMIVGVATCISVFAGLLLGMLAGFYRGIFERMVDLYANTMSALPSILVVLAFVTA
TGPSVLTIMLTLGILDIGTYARVAKAGVISQSNRDYVLAARAMGARDSRILLKEILPNLVPALTAVMPTLMAGLIITEGS
LSFLGYGIPAPAPSWGGMIASSTDLLSRFPLLILGPVMAIILTVYAFNTVGDYFAQRLNSRERES

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=272, Percent_Identity=33.4558823529412, Blast_Score=147, Evalue=6e-37,
Organism=Escherichia coli, GI1789964, Length=259, Percent_Identity=34.7490347490347, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1787498, Length=266, Percent_Identity=30.0751879699248, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1787549, Length=235, Percent_Identity=31.4893617021277, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787760, Length=212, Percent_Identity=32.0754716981132, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1789889, Length=215, Percent_Identity=28.8372093023256, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1788505, Length=195, Percent_Identity=29.7435897435897, Blast_Score=95, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32579; Mature: 32448

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPGTPSPSMADKNSDLSAIVRANMPWSARLRLPGASPFELVALGFLILLVLTAIFVNF
CCCCCCCCCCCCCCCCCHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
IPGLVSPRFPYGDFSQPPEWSLNGLLGTDDIGRSILSRVLYGARASLMIVGVATCISVFA
HHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLLLGMLAGFYRGIFERMVDLYANTMSALPSILVVLAFVTATGPSVLTIMLTLGILDIGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
YARVAKAGVISQSNRDYVLAARAMGARDSRILLKEILPNLVPALTAVMPTLMAGLIITEG
HHHHHHHHHHCCCCCCEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SLSFLGYGIPAPAPSWGGMIASSTDLLSRFPLLILGPVMAIILTVYAFNTVGDYFAQRLN
CHHHHCCCCCCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRERES
HCCCCC
>Mature Secondary Structure 
STPGTPSPSMADKNSDLSAIVRANMPWSARLRLPGASPFELVALGFLILLVLTAIFVNF
CCCCCCCCCCCCCCCCHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
IPGLVSPRFPYGDFSQPPEWSLNGLLGTDDIGRSILSRVLYGARASLMIVGVATCISVFA
HHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLLLGMLAGFYRGIFERMVDLYANTMSALPSILVVLAFVTATGPSVLTIMLTLGILDIGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
YARVAKAGVISQSNRDYVLAARAMGARDSRILLKEILPNLVPALTAVMPTLMAGLIITEG
HHHHHHHHHHCCCCCCEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SLSFLGYGIPAPAPSWGGMIASSTDLLSRFPLLILGPVMAIILTVYAFNTVGDYFAQRLN
CHHHHCCCCCCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRERES
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]