Click here to switch to the map view.

The map label for this gene is bioA [C]

Identifier: 222102796

GI number: 222102796

Start: 458809

End: 460212

Strand: Reverse

Name: bioA [C]

Synonym: Avi_7510

Alternate gene names: 222102796

Gene position: 460212-458809 (Counterclockwise)

Preceding gene: 222102806

Following gene: 222102795

Centisome position: 72.84

GC content: 54.77

Gene sequence:

>1404_bases
ATGATGACGAACATTGCTGAAATCACCGACATGGACCGCCGTACGGTTCTCCATCCCTTCACCTATCTCAAGGATTACGC
CTCCGGTGCCACTGAGCCGACCATCATGGAGACGGGCAAAGGGGTTCGCATCAAGGATGCAACGGGCAGGGAATATATTG
ACGGGTTCGCCGGTCTCTACTGCGTCAACATCGGCTACGGACGCACTGAAGTGGCCGAAGCCATCGCGCGACAGGCTTAC
AAGCTTGCCTACTACCATTCCTACGCAGCCCATACGACAGAAGAGCTCGCGCGCCTGTCTGATCGGCTGATCAGAATGGC
ACCAGGCAATATGTCCAAGGTGTTTTATGGTCTTTCAGGCTCTGACGCCAATGAAACGCAGGCAAAGATCGTCTGGTATT
ACAATAATTTGCGGGGGCTTCCTCGCAAGAAAAAGATCATTGCCCGCGAGCGTGGCTACCATGGCTGCTCGGTTGTCTCT
GGTTCCATGACCGGGCTGAGTTTTTACCATGACCATATGGACCTACCGATATCCGGTATCCTGCGCACCGGCGTTCCGCA
TTTCTATCGTGGTGCTTATCCCGGCGAAACAGAATTGGCCTTTTCTGAACGCCGCGCACACGAACTTGAAGCGCTCATCA
TCGCTGAAGGACCGGACACAGTCGGCGCATTTATTGCCGAGCCGGTTTTAGGCACAGGTGGCATCACACCGCCTCCGGCA
GGTTATTGGCCCAAAATTCAGGCCGTGCTGAAAAAATATGATGTGCTGTTGATCGCTGACGAGGTGATCTGCGGCTTCGG
TCGCACAGGCGCGATGTTCGGCTCTGATTTATACGGGATGGAGCCGGATCTTGTCACTGTCGCCAAGGGATTGACCTCCG
CTTACGTGCCGTTATCGGCCTCAATCATCTCGCAAAAAATATACGACGTTATGGAAGAGGCGACGCCTCGTGTCGGCTCA
TTCTCCCATGGTTACACTTATTCCGGCCATCCGATTGGCGCTGCGGCGGCCAATGCCGTGCTGGATATTGTCGAGCGGGA
AGATCTGGCCGGTCAGGCCGCACAAAAAGGAGCTTACCTGCTCAATAGGCTGAAGGCTGAGTTCGAGCAAAACCCTATTG
TCGGCGAAGTGCGTGGCGTCGGCATGATGGCGGCAATAGAGTTTGTGGCGGATCGCGGATCGAAACTGTCGTTTGATCCG
GCTTTGAAGGTCGGAGGTCGGATTTCTCAGGCGGCACGGGACCGTAATCTCATTGCCCGCGCCATGCCGCATGGAGATAT
TTTGGGCTTTGCGCCACCTTTGGTCATGACAGAGGCGGAGATTGACGAGATGGTGGCTATTACGAAAGCAGCTGTCGATG
AAGTGCTCAAGCAGCTCGATTCTGAAGGTGCTGTGATTGGTTGA

Upstream 100 bases:

>100_bases
AGAACAGACAATCCTGGATACGGCGAAGATGCGTCTCTTTCCCGGGAGTTGATCAAACTGAAATACCTGCGTTACGGCGG
TCTGGCCGCCTGAGGAAATA

Downstream 100 bases:

>100_bases
CCTAAGGAACTCATACAGATGACTGACGTCTTGAAAGTTCACGACCTCGTTAAAGCGTTTGGCTCTGTCAACATCCTCAA
CGGAATCAATTTCCGCATGC

Product: hypothetical protein

Products: L-Glutamate; L-Glutamate 5-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MMTNIAEITDMDRRTVLHPFTYLKDYASGATEPTIMETGKGVRIKDATGREYIDGFAGLYCVNIGYGRTEVAEAIARQAY
KLAYYHSYAAHTTEELARLSDRLIRMAPGNMSKVFYGLSGSDANETQAKIVWYYNNLRGLPRKKKIIARERGYHGCSVVS
GSMTGLSFYHDHMDLPISGILRTGVPHFYRGAYPGETELAFSERRAHELEALIIAEGPDTVGAFIAEPVLGTGGITPPPA
GYWPKIQAVLKKYDVLLIADEVICGFGRTGAMFGSDLYGMEPDLVTVAKGLTSAYVPLSASIISQKIYDVMEEATPRVGS
FSHGYTYSGHPIGAAAANAVLDIVEREDLAGQAAQKGAYLLNRLKAEFEQNPIVGEVRGVGMMAAIEFVADRGSKLSFDP
ALKVGGRISQAARDRNLIARAMPHGDILGFAPPLVMTEAEIDEMVAITKAAVDEVLKQLDSEGAVIG

Sequences:

>Translated_467_residues
MMTNIAEITDMDRRTVLHPFTYLKDYASGATEPTIMETGKGVRIKDATGREYIDGFAGLYCVNIGYGRTEVAEAIARQAY
KLAYYHSYAAHTTEELARLSDRLIRMAPGNMSKVFYGLSGSDANETQAKIVWYYNNLRGLPRKKKIIARERGYHGCSVVS
GSMTGLSFYHDHMDLPISGILRTGVPHFYRGAYPGETELAFSERRAHELEALIIAEGPDTVGAFIAEPVLGTGGITPPPA
GYWPKIQAVLKKYDVLLIADEVICGFGRTGAMFGSDLYGMEPDLVTVAKGLTSAYVPLSASIISQKIYDVMEEATPRVGS
FSHGYTYSGHPIGAAAANAVLDIVEREDLAGQAAQKGAYLLNRLKAEFEQNPIVGEVRGVGMMAAIEFVADRGSKLSFDP
ALKVGGRISQAARDRNLIARAMPHGDILGFAPPLVMTEAEIDEMVAITKAAVDEVLKQLDSEGAVIG
>Mature_467_residues
MMTNIAEITDMDRRTVLHPFTYLKDYASGATEPTIMETGKGVRIKDATGREYIDGFAGLYCVNIGYGRTEVAEAIARQAY
KLAYYHSYAAHTTEELARLSDRLIRMAPGNMSKVFYGLSGSDANETQAKIVWYYNNLRGLPRKKKIIARERGYHGCSVVS
GSMTGLSFYHDHMDLPISGILRTGVPHFYRGAYPGETELAFSERRAHELEALIIAEGPDTVGAFIAEPVLGTGGITPPPA
GYWPKIQAVLKKYDVLLIADEVICGFGRTGAMFGSDLYGMEPDLVTVAKGLTSAYVPLSASIISQKIYDVMEEATPRVGS
FSHGYTYSGHPIGAAAANAVLDIVEREDLAGQAAQKGAYLLNRLKAEFEQNPIVGEVRGVGMMAAIEFVADRGSKLSFDP
ALKVGGRISQAARDRNLIARAMPHGDILGFAPPLVMTEAEIDEMVAITKAAVDEVLKQLDSEGAVIG

Specific function: Unknown

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=455, Percent_Identity=29.6703296703297, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI13994255, Length=453, Percent_Identity=26.2693156732892, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI37574042, Length=428, Percent_Identity=27.803738317757, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI226442705, Length=426, Percent_Identity=27.4647887323944, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI226442709, Length=361, Percent_Identity=29.0858725761773, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI24119277, Length=437, Percent_Identity=24.9427917620137, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI284507298, Length=246, Percent_Identity=34.5528455284553, Blast_Score=121, Evalue=1e-27,
Organism=Escherichia coli, GI145693181, Length=411, Percent_Identity=29.1970802919708, Blast_Score=161, Evalue=7e-41,
Organism=Escherichia coli, GI1789016, Length=436, Percent_Identity=29.3577981651376, Blast_Score=154, Evalue=9e-39,
Organism=Escherichia coli, GI1788044, Length=414, Percent_Identity=29.2270531400966, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1789759, Length=420, Percent_Identity=28.5714285714286, Blast_Score=149, Evalue=5e-37,
Organism=Escherichia coli, GI1787560, Length=428, Percent_Identity=28.7383177570093, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1786991, Length=451, Percent_Identity=24.6119733924612, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1786349, Length=318, Percent_Identity=26.4150943396226, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI32564660, Length=475, Percent_Identity=26.3157894736842, Blast_Score=160, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI25144271, Length=464, Percent_Identity=27.1551724137931, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI71992977, Length=446, Percent_Identity=25.3363228699552, Blast_Score=128, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI25144274, Length=252, Percent_Identity=32.5396825396825, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17541228, Length=460, Percent_Identity=22.8260869565217, Blast_Score=82, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6323470, Length=430, Percent_Identity=29.7674418604651, Blast_Score=161, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6324432, Length=367, Percent_Identity=29.4277929155313, Blast_Score=141, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6324386, Length=489, Percent_Identity=25.3578732106339, Blast_Score=127, Evalue=6e-30,
Organism=Drosophila melanogaster, GI28574759, Length=447, Percent_Identity=27.5167785234899, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI161085790, Length=431, Percent_Identity=27.3781902552204, Blast_Score=163, Evalue=3e-40,
Organism=Drosophila melanogaster, GI21357415, Length=425, Percent_Identity=28.2352941176471, Blast_Score=142, Evalue=6e-34,
Organism=Drosophila melanogaster, GI21356575, Length=442, Percent_Identity=27.3755656108597, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI281366494, Length=382, Percent_Identity=23.2984293193717, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24667139, Length=382, Percent_Identity=23.2984293193717, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24667143, Length=382, Percent_Identity=23.2984293193717, Blast_Score=75, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.13 [C]

Molecular weight: Translated: 50607; Mature: 50607

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTNIAEITDMDRRTVLHPFTYLKDYASGATEPTIMETGKGVRIKDATGREYIDGFAGLY
CCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCEECCCCEEEECCCCHHHHHHHCCEE
CVNIGYGRTEVAEAIARQAYKLAYYHSYAAHTTEELARLSDRLIRMAPGNMSKVFYGLSG
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEECCC
SDANETQAKIVWYYNNLRGLPRKKKIIARERGYHGCSVVSGSMTGLSFYHDHMDLPISGI
CCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCCCEEECCCCCCHHHHHCCCCCCHHHH
LRTGVPHFYRGAYPGETELAFSERRAHELEALIIAEGPDTVGAFIAEPVLGTGGITPPPA
HHHCCCHHHCCCCCCCCCHHHHHHHHCCEEEEEEECCCCHHHHHHHCCCCCCCCCCCCCC
GYWPKIQAVLKKYDVLLIADEVICGFGRTGAMFGSDLYGMEPDLVTVAKGLTSAYVPLSA
CCCHHHHHHHHHCCEEEEEHHHHHCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHCCHHH
SIISQKIYDVMEEATPRVGSFSHGYTYSGHPIGAAAANAVLDIVEREDLAGQAAQKGAYL
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNRLKAEFEQNPIVGEVRGVGMMAAIEFVADRGSKLSFDPALKVGGRISQAARDRNLIAR
HHHHHHHHHCCCCEEHHHCCHHHHHHHHHHCCCCCCCCCHHHHHCCHHHHHHHHHHHHHH
AMPHGDILGFAPPLVMTEAEIDEMVAITKAAVDEVLKQLDSEGAVIG
HCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MMTNIAEITDMDRRTVLHPFTYLKDYASGATEPTIMETGKGVRIKDATGREYIDGFAGLY
CCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCEECCCCEEEECCCCHHHHHHHCCEE
CVNIGYGRTEVAEAIARQAYKLAYYHSYAAHTTEELARLSDRLIRMAPGNMSKVFYGLSG
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEECCC
SDANETQAKIVWYYNNLRGLPRKKKIIARERGYHGCSVVSGSMTGLSFYHDHMDLPISGI
CCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCCCEEECCCCCCHHHHHCCCCCCHHHH
LRTGVPHFYRGAYPGETELAFSERRAHELEALIIAEGPDTVGAFIAEPVLGTGGITPPPA
HHHCCCHHHCCCCCCCCCHHHHHHHHCCEEEEEEECCCCHHHHHHHCCCCCCCCCCCCCC
GYWPKIQAVLKKYDVLLIADEVICGFGRTGAMFGSDLYGMEPDLVTVAKGLTSAYVPLSA
CCCHHHHHHHHHCCEEEEEHHHHHCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHCCHHH
SIISQKIYDVMEEATPRVGSFSHGYTYSGHPIGAAAANAVLDIVEREDLAGQAAQKGAYL
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNRLKAEFEQNPIVGEVRGVGMMAAIEFVADRGSKLSFDPALKVGGRISQAARDRNLIAR
HHHHHHHHHCCCCEEHHHCCHHHHHHHHHHCCCCCCCCCHHHHHCCHHHHHHHHHHHHHH
AMPHGDILGFAPPLVMTEAEIDEMVAITKAAVDEVLKQLDSEGAVIG
HCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; Ornithine [C]

Specific reaction: 2-Oxoglutarate + Ornithine --> L-Glutamate + L-Glutamate 5-semialdehyde [C]

General reaction: Amino group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8796346; 9163424 [H]