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The map label for this gene is nocR [H]

Identifier: 222102806

GI number: 222102806

Start: 470060

End: 471931

Strand: Reverse

Name: nocR [H]

Synonym: Avi_7526

Alternate gene names: 222102806

Gene position: 471931-470060 (Counterclockwise)

Preceding gene: 222102820

Following gene: 222102796

Centisome position: 74.7

GC content: 54.97

Gene sequence:

>1872_bases
ATGGACCATTACGGCATTGAGCTCAAGCCTCTCGCGAAATTCGTTCTGGCGTGCCAGAATCCCAGCATTTCCAATTCGTC
CCGCGCGCTTGGAATAGCTCCATCCGTTTTGAGCGCTGCTTTACACGGCTTGGAAGATCGCCTGCATATGAAGCTTTTCG
AGCGCAAAGGGCGCTACCTCGGCCTTTTGCCATCAGCCTTCTGGCTTTATCGAAATGCGGCAGTGCTTCTGCATCTGGAG
GAATTTTCAAGACGCAGTCTGGCTATCCCTGCAAACCGGATGGAAAAGCTGTCCGTTCGGATCGACCTGAATTTTTCCAT
CGGCAGAATGACGAAGGCGGTGAGCTGTGCCATTCAGCAAATGGGCCTACAGCACCCCGAAACCTTTATAGCCTGCCAGT
TTCTCGACACAGCCAGTGCAGCAAGCGGTGGTTTCATCAGAGAATCCATGGATCACATTCCAGCCGAACATTGCGCCACG
ATTGAGATCGGCTGTCATAATGAGCACTCGTTCCGGGAAGAGCCTGGGACTGAATTATTGTATCGCGACCCGTGGATAGC
CGTCAGCGCCACGGATCCGGTGACAGATATTAAAGCCGATGCGGATATTCTAGCTGTTGTCAGGATGAGCGCTCACCAGA
TGCAGGTCGTTGCCCATTATGCGGATCAGCATGGGTTATCCGCGCGGCTGAAATTCGTGGACGCCGGACCAGCAGAACTT
GGGCGTCTTCTCTCGGATTTTCCCCATATGCGGTTTTTGTTGCCCTCCAGCATGGTGGCCAATCGGCTGGGAATCAGCCG
TATTTATCGCGAATCTCTGGTGCCGCCTCTGGTGTCTATGGTGCGTGTGGGCACAAGCGGTGCATTGGAGACAAAAGCAC
GACGTTTTATAGGGCTGCTGCGGGAAAATATGGAAGGCGAAGAGCAAAATGTTGTGTTTGATCCCCAACTGACGGCGCGC
CAGATGCATTATTTCAATCTTGTCCACCGCTGCGGCGGCATTTCAGCGGCGGCGCGGGTGGCTAATCTCGCCCAGTCTTC
GGTGTCCGCACAGCTTCATTCTATGGAAGCAGTTCTGGGAACACCTCTCTTTGAGCGCAGCAAGGAGGGTGCCACGCCAA
CCGATGCGGGCATTAATCTTTGGCCCCTGATGGCAGAGGTGGAGAAGCGGCAGGATCGGCTGTCGCGGCAATCCGGCGAT
ATTGCGGCCCATACCCAGCACCGCGTCTCGATTGGCATGTTGCCCAGCTCCGGCCACGATAGCGCCTTGACCGAAAAAAT
TGCTGAGGCGCTGACTATGATCAGCATTCAGCATCCCTCGCTGAAAATGGAAATAACGGAAGCGTCAAACACGATCCTGC
ATGACAAAGTTCGTTCTGGTGAACTGAATCTTGCTATTGTCGGGGTGGTCCAGCCTCAGTTTCCACGCGTGCTGCTTGGC
CCCAGCGAGCCATTGTCGGTGGTTGCCAATCCGCGGTTCAATTTTGGCGGACGCAGCGAGATCAATCTGGCCGAAGTCTG
CGAACTGCCGCTTGTGCTGGGTGCGCGCCATCTCAGCATTCACCAGAGTTTTGCTGCAGCCACCCACGCGCGCAATCTGG
AGCCGCATTCGAAGATTGAAGTCGGCTCTCTTGCACTGGCCATCGCCATGGTTCGCCGCGCCAGTCTGTGCACAATCTTG
CCGGCCTCTTCTGTGCAAAAAGACCTGGAGACCGGGCGTCTTGTGGCTATAAAGATCAATCAGGAAGAAATTTCCGGGAC
ACTCTCCATCATTTTTTCCGCTGATCGGGAGCTATCCGGCGCTGAGCGCGCCGTGATGAAAACGCTGGTGGATGTGTTTG
GCAAGAAATTACATGAGGGCCTTGCGCGATAA

Upstream 100 bases:

>100_bases
TCCCGCAAGGATTGAAACCATGTGAAATTTGCCCAACGTTCTCTCGGAAATCGTTGTTACGTCACTTGAGAGCCACGCAG
CGTAACCCTATGCTCGGCGA

Downstream 100 bases:

>100_bases
GCGTTTCAGCGTGTCACGCTCACCACCGCTTCCACAAAATTGTTGATCTGCTCGTGGCGCAGCCCCGCAATGTTGATACG
ACTGTCCTCAACCATGTAAA

Product: transcriptional regulator LysR family

Products: NA

Alternate protein names: Nitrogen assimilation control protein [H]

Number of amino acids: Translated: 623; Mature: 623

Protein sequence:

>623_residues
MDHYGIELKPLAKFVLACQNPSISNSSRALGIAPSVLSAALHGLEDRLHMKLFERKGRYLGLLPSAFWLYRNAAVLLHLE
EFSRRSLAIPANRMEKLSVRIDLNFSIGRMTKAVSCAIQQMGLQHPETFIACQFLDTASAASGGFIRESMDHIPAEHCAT
IEIGCHNEHSFREEPGTELLYRDPWIAVSATDPVTDIKADADILAVVRMSAHQMQVVAHYADQHGLSARLKFVDAGPAEL
GRLLSDFPHMRFLLPSSMVANRLGISRIYRESLVPPLVSMVRVGTSGALETKARRFIGLLRENMEGEEQNVVFDPQLTAR
QMHYFNLVHRCGGISAAARVANLAQSSVSAQLHSMEAVLGTPLFERSKEGATPTDAGINLWPLMAEVEKRQDRLSRQSGD
IAAHTQHRVSIGMLPSSGHDSALTEKIAEALTMISIQHPSLKMEITEASNTILHDKVRSGELNLAIVGVVQPQFPRVLLG
PSEPLSVVANPRFNFGGRSEINLAEVCELPLVLGARHLSIHQSFAAATHARNLEPHSKIEVGSLALAIAMVRRASLCTIL
PASSVQKDLETGRLVAIKINQEEISGTLSIIFSADRELSGAERAVMKTLVDVFGKKLHEGLAR

Sequences:

>Translated_623_residues
MDHYGIELKPLAKFVLACQNPSISNSSRALGIAPSVLSAALHGLEDRLHMKLFERKGRYLGLLPSAFWLYRNAAVLLHLE
EFSRRSLAIPANRMEKLSVRIDLNFSIGRMTKAVSCAIQQMGLQHPETFIACQFLDTASAASGGFIRESMDHIPAEHCAT
IEIGCHNEHSFREEPGTELLYRDPWIAVSATDPVTDIKADADILAVVRMSAHQMQVVAHYADQHGLSARLKFVDAGPAEL
GRLLSDFPHMRFLLPSSMVANRLGISRIYRESLVPPLVSMVRVGTSGALETKARRFIGLLRENMEGEEQNVVFDPQLTAR
QMHYFNLVHRCGGISAAARVANLAQSSVSAQLHSMEAVLGTPLFERSKEGATPTDAGINLWPLMAEVEKRQDRLSRQSGD
IAAHTQHRVSIGMLPSSGHDSALTEKIAEALTMISIQHPSLKMEITEASNTILHDKVRSGELNLAIVGVVQPQFPRVLLG
PSEPLSVVANPRFNFGGRSEINLAEVCELPLVLGARHLSIHQSFAAATHARNLEPHSKIEVGSLALAIAMVRRASLCTIL
PASSVQKDLETGRLVAIKINQEEISGTLSIIFSADRELSGAERAVMKTLVDVFGKKLHEGLAR
>Mature_623_residues
MDHYGIELKPLAKFVLACQNPSISNSSRALGIAPSVLSAALHGLEDRLHMKLFERKGRYLGLLPSAFWLYRNAAVLLHLE
EFSRRSLAIPANRMEKLSVRIDLNFSIGRMTKAVSCAIQQMGLQHPETFIACQFLDTASAASGGFIRESMDHIPAEHCAT
IEIGCHNEHSFREEPGTELLYRDPWIAVSATDPVTDIKADADILAVVRMSAHQMQVVAHYADQHGLSARLKFVDAGPAEL
GRLLSDFPHMRFLLPSSMVANRLGISRIYRESLVPPLVSMVRVGTSGALETKARRFIGLLRENMEGEEQNVVFDPQLTAR
QMHYFNLVHRCGGISAAARVANLAQSSVSAQLHSMEAVLGTPLFERSKEGATPTDAGINLWPLMAEVEKRQDRLSRQSGD
IAAHTQHRVSIGMLPSSGHDSALTEKIAEALTMISIQHPSLKMEITEASNTILHDKVRSGELNLAIVGVVQPQFPRVLLG
PSEPLSVVANPRFNFGGRSEINLAEVCELPLVLGARHLSIHQSFAAATHARNLEPHSKIEVGSLALAIAMVRRASLCTIL
PASSVQKDLETGRLVAIKINQEEISGTLSIIFSADRELSGAERAVMKTLVDVFGKKLHEGLAR

Specific function: Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation. Negative regulator of its own expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=256, Percent_Identity=24.609375, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI87081904, Length=296, Percent_Identity=22.6351351351351, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 68181; Mature: 68181

Theoretical pI: Translated: 7.59; Mature: 7.59

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDHYGIELKPLAKFVLACQNPSISNSSRALGIAPSVLSAALHGLEDRLHMKLFERKGRYL
CCCCCCCHHHHHHHHHHCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHCCCEE
GLLPSAFWLYRNAAVLLHLEEFSRRSLAIPANRMEKLSVRIDLNFSIGRMTKAVSCAIQQ
EECHHHHHHHHCCEEEEEEHHHCCCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHH
MGLQHPETFIACQFLDTASAASGGFIRESMDHIPAEHCATIEIGCHNEHSFREEPGTELL
HCCCCCCCEEEEEEHHCCCCCCCCHHHHHHHCCCHHHCEEEEEECCCCCCCCCCCCCEEE
YRDPWIAVSATDPVTDIKADADILAVVRMSAHQMQVVAHYADQHGLSARLKFVDAGPAEL
EECCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCHHHH
GRLLSDFPHMRFLLPSSMVANRLGISRIYRESLVPPLVSMVRVGTSGALETKARRFIGLL
HHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHH
RENMEGEEQNVVFDPQLTARQMHYFNLVHRCGGISAAARVANLAQSSVSAQLHSMEAVLG
HHCCCCCCCCEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
TPLFERSKEGATPTDAGINLWPLMAEVEKRQDRLSRQSGDIAAHTQHRVSIGMLPSSGHD
CCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEEECCCCCCC
SALTEKIAEALTMISIQHPSLKMEITEASNTILHDKVRSGELNLAIVGVVQPQFPRVLLG
HHHHHHHHHHHHHHEEECCCEEEEEECCCCCEEHHHCCCCCEEEEEEEEECCCCCEEEEC
PSEPLSVVANPRFNFGGRSEINLAEVCELPLVLGARHLSIHQSFAAATHARNLEPHSKIE
CCCCCEEEECCCCCCCCCCCCCHHHHHCCHHHHCCHHHHHHHHHHHHHHHCCCCCCCCEE
VGSLALAIAMVRRASLCTILPASSVQKDLETGRLVAIKINQEEISGTLSIIFSADRELSG
HHHHHHHHHHHHHHHHEEECCCHHHHHHHCCCCEEEEEECHHHHCCEEEEEEECCCCCCH
AERAVMKTLVDVFGKKLHEGLAR
HHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDHYGIELKPLAKFVLACQNPSISNSSRALGIAPSVLSAALHGLEDRLHMKLFERKGRYL
CCCCCCCHHHHHHHHHHCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHCCCEE
GLLPSAFWLYRNAAVLLHLEEFSRRSLAIPANRMEKLSVRIDLNFSIGRMTKAVSCAIQQ
EECHHHHHHHHCCEEEEEEHHHCCCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHH
MGLQHPETFIACQFLDTASAASGGFIRESMDHIPAEHCATIEIGCHNEHSFREEPGTELL
HCCCCCCCEEEEEEHHCCCCCCCCHHHHHHHCCCHHHCEEEEEECCCCCCCCCCCCCEEE
YRDPWIAVSATDPVTDIKADADILAVVRMSAHQMQVVAHYADQHGLSARLKFVDAGPAEL
EECCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCHHHH
GRLLSDFPHMRFLLPSSMVANRLGISRIYRESLVPPLVSMVRVGTSGALETKARRFIGLL
HHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHH
RENMEGEEQNVVFDPQLTARQMHYFNLVHRCGGISAAARVANLAQSSVSAQLHSMEAVLG
HHCCCCCCCCEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
TPLFERSKEGATPTDAGINLWPLMAEVEKRQDRLSRQSGDIAAHTQHRVSIGMLPSSGHD
CCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEEECCCCCCC
SALTEKIAEALTMISIQHPSLKMEITEASNTILHDKVRSGELNLAIVGVVQPQFPRVLLG
HHHHHHHHHHHHHHEEECCCEEEEEECCCCCEEHHHCCCCCEEEEEEEEECCCCCEEEEC
PSEPLSVVANPRFNFGGRSEINLAEVCELPLVLGARHLSIHQSFAAATHARNLEPHSKIE
CCCCCEEEECCCCCCCCCCCCCHHHHHCCHHHHCCHHHHHHHHHHHHHHHCCCCCCCCEE
VGSLALAIAMVRRASLCTILPASSVQKDLETGRLVAIKINQEEISGTLSIIFSADRELSG
HHHHHHHHHHHHHHHHEEECCCHHHHHHHCCCCEEEEEECHHHHCCEEEEEEECCCCCCH
AERAVMKTLVDVFGKKLHEGLAR
HHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8458853 [H]