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The map label for this gene is chvI [H]

Identifier: 222102784

GI number: 222102784

Start: 446416

End: 447102

Strand: Direct

Name: chvI [H]

Synonym: Avi_7488

Alternate gene names: 222102784

Gene position: 446416-447102 (Clockwise)

Preceding gene: 222102780

Following gene: 222102785

Centisome position: 70.66

GC content: 57.06

Gene sequence:

>687_bases
ATGACCAATGTCCTCTTGATTGACGATGACACGGAGCTGACCACGATTCTGAGTGAGTACCTGACAGGGGAGGGTTTCAC
GGTATTCGCAGTGGTCAATGGCAAGCAGGGACTGGCCGAGATCGCTGCCCGCAGGATCGATATGGTCGTCCTTGATATCA
TGATGCCGCAAATGAACGGAATTGATGTTCTGCAGCGGATACGCCGTGTCAGCGAGGTCCCCGTCCTCATGCTCACCGCC
CGTGGCGATGACGTAGACCGCATTTCCGGCCTCAACCTGGGTGCCGATGATTATGTGGCGAAACCCTGTTCATCCGGTGA
GCTTGTGGCCCGACTACGCGCTATCCTCAGGCGCGTTGGACCAGACAAGGATGTCGAGACTGAGCAATTACGATCCGGCG
ATCTGGTTCTGAACCCGGCCAACAGAACTGCGGAATGGCGAGGCCTGCCGTTTGAACTGACAGGAACGGAATTTATCCTG
CTTGAAGTCCTGGTGCGCAATGCGGGACAGCTGATTTCAAGGCAGTTTATCTCAAAGCAGGCATTTGGCCGTCCGCTCGT
CGCCTTTGACCGGCGTATCGACGTCCACATCAGCAGCGTGCGGCAGAAACTGGGCCGACGCGAGGACGGGCAGTCCTGGA
TCCAGTCCGTTCGCGGGCAGGGTTATCAACTCATCCGGGATGTTTGA

Upstream 100 bases:

>100_bases
TAAGTGCCGTCAGGGATGTGTAAAATTGGGTAAAATAACACTTGCTAGCCGTGCGGCCGGTTTATCCTGTCCTTTATAAG
TTCAATGGCAGACCAGATCG

Downstream 100 bases:

>100_bases
TGACAAGGCTTTTCCGAAAATTCTTCATTTTCGTCTGGCTGGCGATGACCGTGTCCATTGTTGGCATCATTTCATTGGAT
AGGGTCTTCCATCTGTTTCC

Product: two component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MTNVLLIDDDTELTTILSEYLTGEGFTVFAVVNGKQGLAEIAARRIDMVVLDIMMPQMNGIDVLQRIRRVSEVPVLMLTA
RGDDVDRISGLNLGADDYVAKPCSSGELVARLRAILRRVGPDKDVETEQLRSGDLVLNPANRTAEWRGLPFELTGTEFIL
LEVLVRNAGQLISRQFISKQAFGRPLVAFDRRIDVHISSVRQKLGRREDGQSWIQSVRGQGYQLIRDV

Sequences:

>Translated_228_residues
MTNVLLIDDDTELTTILSEYLTGEGFTVFAVVNGKQGLAEIAARRIDMVVLDIMMPQMNGIDVLQRIRRVSEVPVLMLTA
RGDDVDRISGLNLGADDYVAKPCSSGELVARLRAILRRVGPDKDVETEQLRSGDLVLNPANRTAEWRGLPFELTGTEFIL
LEVLVRNAGQLISRQFISKQAFGRPLVAFDRRIDVHISSVRQKLGRREDGQSWIQSVRGQGYQLIRDV
>Mature_227_residues
TNVLLIDDDTELTTILSEYLTGEGFTVFAVVNGKQGLAEIAARRIDMVVLDIMMPQMNGIDVLQRIRRVSEVPVLMLTAR
GDDVDRISGLNLGADDYVAKPCSSGELVARLRAILRRVGPDKDVETEQLRSGDLVLNPANRTAEWRGLPFELTGTEFILL
EVLVRNAGQLISRQFISKQAFGRPLVAFDRRIDVHISSVRQKLGRREDGQSWIQSVRGQGYQLIRDV

Specific function: Member of the two-component regulatory system CpxA/CpxR. This system combats a variety of extracytoplasmic protein-mediated toxicities. It performs this function by increasing the synthesis of the periplasmic protease, DegP as well as that of CpxP protein

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=45.2173913043478, Blast_Score=200, Evalue=6e-53,
Organism=Escherichia coli, GI1788394, Length=220, Percent_Identity=35, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=36.9565217391304, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1789402, Length=222, Percent_Identity=36.9369369369369, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1786911, Length=229, Percent_Identity=34.061135371179, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=34.9775784753363, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI1786784, Length=223, Percent_Identity=34.9775784753363, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=32.3008849557522, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1790552, Length=225, Percent_Identity=34.2222222222222, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=32.7586206896552, Blast_Score=112, Evalue=1e-26,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=32, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=28.3261802575107, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=27.7056277056277, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1787375, Length=225, Percent_Identity=28.8888888888889, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790299, Length=108, Percent_Identity=35.1851851851852, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790437, Length=115, Percent_Identity=33.9130434782609, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788550, Length=106, Percent_Identity=33.9622641509434, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788905, Length=124, Percent_Identity=29.8387096774194, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25476; Mature: 25345

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNVLLIDDDTELTTILSEYLTGEGFTVFAVVNGKQGLAEIAARRIDMVVLDIMMPQMNG
CCCEEEEECCCHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCC
IDVLQRIRRVSEVPVLMLTARGDDVDRISGLNLGADDYVAKPCSSGELVARLRAILRRVG
HHHHHHHHHHHCCCEEEEEECCCCHHHHCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHCC
PDKDVETEQLRSGDLVLNPANRTAEWRGLPFELTGTEFILLEVLVRNAGQLISRQFISKQ
CCCCCCHHHHCCCCEEECCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
AFGRPLVAFDRRIDVHISSVRQKLGRREDGQSWIQSVRGQGYQLIRDV
HCCCCHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHCC
>Mature Secondary Structure 
TNVLLIDDDTELTTILSEYLTGEGFTVFAVVNGKQGLAEIAARRIDMVVLDIMMPQMNG
CCEEEEECCCHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCC
IDVLQRIRRVSEVPVLMLTARGDDVDRISGLNLGADDYVAKPCSSGELVARLRAILRRVG
HHHHHHHHHHHCCCEEEEEECCCCHHHHCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHCC
PDKDVETEQLRSGDLVLNPANRTAEWRGLPFELTGTEFILLEVLVRNAGQLISRQFISKQ
CCCCCCHHHHCCCCEEECCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
AFGRPLVAFDRRIDVHISSVRQKLGRREDGQSWIQSVRGQGYQLIRDV
HCCCCHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]