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The map label for this gene is macA [H]

Identifier: 222102754

GI number: 222102754

Start: 408815

End: 409888

Strand: Reverse

Name: macA [H]

Synonym: Avi_7440

Alternate gene names: 222102754

Gene position: 409888-408815 (Counterclockwise)

Preceding gene: 222102756

Following gene: 222102753

Centisome position: 64.88

GC content: 59.03

Gene sequence:

>1074_bases
ATGTCATATTTCCGCGAAGAGTTTGCGTCGACCTGGCCGGCATTGCGTGTGCGTTTCGGCGTTGGTGTGCGTCACGATCT
GGTCGCAGAAATCACACGGTTGGAATGTCATCGTGCGCTGATCCTGACAACGCCGGAACAGGCGCATGTCGCGGAAGAGT
TCGCGGCCCGGTGTGGCGACCACGCAGCAGGCATTTTTACCCGCGCCCGAATGCATACACCTGTGGACATATCGGAGGAA
GCAACGGCTTATGCCCGCGACATTGGCGCCGATTGTCTGGTCGCCATTGGCGGCGGCTCCACAACCGGCCTTGGCAAGGC
CATTGCTTTGCGCAGTGATCTGCCACAAATCGTTGTTCCAACGACCTATGCGGGCAGTGAAGCAACCGCCATTCTCGGAC
AGACGGAAAATGGCGTTAAAACCACATTGACCAGCGCCAAGGTTCAGCCCGAAGTTATTCTCTATGATGCAGAACTGGTG
CGCAGCCTGCCCGTTGGCATGACCGTGACCAGCGCGTTGAATGCGATGGCCCATGCTGCCGAAGGCCTTTATGCGCAAAA
CCGTACCCCCTTGACCACGCTGATGGCGCTTGAAGGGCTGCGCGCCTTTCGCGATGCCCTGCCCCGTGTTCTAAAAGATC
CGTCCGATCTCAAGGCGCGTGGTGAAACGCTCTATGGCGCATGGTTGTGCGGAACGGTGCTGGGTCAGGTCGGCATGGCA
CTGCACCACAAGCTCTGCCACACGCTGGGTGGTAGCTTTGATTTGCCGCATGCTGAAACGCACGCTGTGATCTTGCCGCA
TGCAATCGCCTACAACAGCGTTGCCGCGCAGGGTGAATTGCGCCCATTGGCTGAGCTGTTCGGGGGGCAAGAGCCAGGAG
CCGAGCTTTATGACTTTGCCCGCACATCGCATGCTCCGATGGCTCTGAAAGACCTTGGATTGAAGGAGAGCGACCTTGAT
CGGGCAGCCGATCTTGCGGCGCAAAATCCATACTGGAATCCACGTCCTGTGGAGCGGGACGCGATAAGGCGGCTTTTGCA
AGCGGCATGGACCGGAGAGCCGCCGGTCGCCTGA

Upstream 100 bases:

>100_bases
ACAAAAGATTATATTATATCGCCACCTTCCGATCAATATCCGCCTTTCACTGATCTATTGTCGCCTTCATAGGAGCCAGA
CAGTCGGCAGGAGGAGCCCC

Downstream 100 bases:

>100_bases
CAGAGTTGAAGAGGGAGGAAATTGACAAATGGCAGACATTACAACGGATGTGCTGATTATCGGCACTGGACCGGCAGGCT
CGGCAGCGGCAGCCCTGCTG

Product: maleylacetate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MSYFREEFASTWPALRVRFGVGVRHDLVAEITRLECHRALILTTPEQAHVAEEFAARCGDHAAGIFTRARMHTPVDISEE
ATAYARDIGADCLVAIGGGSTTGLGKAIALRSDLPQIVVPTTYAGSEATAILGQTENGVKTTLTSAKVQPEVILYDAELV
RSLPVGMTVTSALNAMAHAAEGLYAQNRTPLTTLMALEGLRAFRDALPRVLKDPSDLKARGETLYGAWLCGTVLGQVGMA
LHHKLCHTLGGSFDLPHAETHAVILPHAIAYNSVAAQGELRPLAELFGGQEPGAELYDFARTSHAPMALKDLGLKESDLD
RAADLAAQNPYWNPRPVERDAIRRLLQAAWTGEPPVA

Sequences:

>Translated_357_residues
MSYFREEFASTWPALRVRFGVGVRHDLVAEITRLECHRALILTTPEQAHVAEEFAARCGDHAAGIFTRARMHTPVDISEE
ATAYARDIGADCLVAIGGGSTTGLGKAIALRSDLPQIVVPTTYAGSEATAILGQTENGVKTTLTSAKVQPEVILYDAELV
RSLPVGMTVTSALNAMAHAAEGLYAQNRTPLTTLMALEGLRAFRDALPRVLKDPSDLKARGETLYGAWLCGTVLGQVGMA
LHHKLCHTLGGSFDLPHAETHAVILPHAIAYNSVAAQGELRPLAELFGGQEPGAELYDFARTSHAPMALKDLGLKESDLD
RAADLAAQNPYWNPRPVERDAIRRLLQAAWTGEPPVA
>Mature_356_residues
SYFREEFASTWPALRVRFGVGVRHDLVAEITRLECHRALILTTPEQAHVAEEFAARCGDHAAGIFTRARMHTPVDISEEA
TAYARDIGADCLVAIGGGSTTGLGKAIALRSDLPQIVVPTTYAGSEATAILGQTENGVKTTLTSAKVQPEVILYDAELVR
SLPVGMTVTSALNAMAHAAEGLYAQNRTPLTTLMALEGLRAFRDALPRVLKDPSDLKARGETLYGAWLCGTVLGQVGMAL
HHKLCHTLGGSFDLPHAETHAVILPHAIAYNSVAAQGELRPLAELFGGQEPGAELYDFARTSHAPMALKDLGLKESDLDR
AADLAAQNPYWNPRPVERDAIRRLLQAAWTGEPPVA

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI48994951, Length=299, Percent_Identity=27.4247491638796, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1789163, Length=375, Percent_Identity=25.3333333333333, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87082107, Length=213, Percent_Identity=29.5774647887324, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1787493, Length=249, Percent_Identity=22.8915662650602, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17537053, Length=419, Percent_Identity=23.3890214797136, Blast_Score=85, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6321181, Length=368, Percent_Identity=26.3586956521739, Blast_Score=112, Evalue=6e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.3.1.32 [H]

Molecular weight: Translated: 38357; Mature: 38226

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYFREEFASTWPALRVRFGVGVRHDLVAEITRLECHRALILTTPEQAHVAEEFAARCGD
CCHHHHHHHCCCHHHEEEECCCCHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHCCC
HAAGIFTRARMHTPVDISEEATAYARDIGADCLVAIGGGSTTGLGKAIALRSDLPQIVVP
HHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHCCCCCEEEE
TTYAGSEATAILGQTENGVKTTLTSAKVQPEVILYDAELVRSLPVGMTVTSALNAMAHAA
CCCCCCCCEEEECCCCCCCHHHHHHCCCCCEEEEECHHHHHHCCCCHHHHHHHHHHHHHH
EGLYAQNRTPLTTLMALEGLRAFRDALPRVLKDPSDLKARGETLYGAWLCGTVLGQVGMA
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHH
LHHKLCHTLGGSFDLPHAETHAVILPHAIAYNSVAAQGELRPLAELFGGQEPGAELYDFA
HHHHHHHHCCCCCCCCCCCCCEEEECHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHH
RTSHAPMALKDLGLKESDLDRAADLAAQNPYWNPRPVERDAIRRLLQAAWTGEPPVA
HCCCCCHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SYFREEFASTWPALRVRFGVGVRHDLVAEITRLECHRALILTTPEQAHVAEEFAARCGD
CHHHHHHHCCCHHHEEEECCCCHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHCCC
HAAGIFTRARMHTPVDISEEATAYARDIGADCLVAIGGGSTTGLGKAIALRSDLPQIVVP
HHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHCCCCCEEEE
TTYAGSEATAILGQTENGVKTTLTSAKVQPEVILYDAELVRSLPVGMTVTSALNAMAHAA
CCCCCCCCEEEECCCCCCCHHHHHHCCCCCEEEEECHHHHHHCCCCHHHHHHHHHHHHHH
EGLYAQNRTPLTTLMALEGLRAFRDALPRVLKDPSDLKARGETLYGAWLCGTVLGQVGMA
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHH
LHHKLCHTLGGSFDLPHAETHAVILPHAIAYNSVAAQGELRPLAELFGGQEPGAELYDFA
HHHHHHHHCCCCCCCCCCCCCEEEECHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHH
RTSHAPMALKDLGLKESDLDRAADLAAQNPYWNPRPVERDAIRRLLQAAWTGEPPVA
HCCCCCHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7538273 [H]