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The map label for this gene is 222102731

Identifier: 222102731

GI number: 222102731

Start: 384226

End: 385377

Strand: Direct

Name: 222102731

Synonym: Avi_7411

Alternate gene names: NA

Gene position: 384226-385377 (Clockwise)

Preceding gene: 222102730

Following gene: 222102732

Centisome position: 60.82

GC content: 58.16

Gene sequence:

>1152_bases
ATGAGTATCCGTGGCAAGGCCTTTATTGTTGGGGCCTACGAGCATCCGGGCCGTAATCTGCCTGACCATTCAGTGCAGCA
AATCCATGCAGAATGTGCGATGGGCGCACTTAGCGACGCGGGCCTGTCCATCAAAGACGTGGATGGTTATTTCAGCAATG
GCCAATTGGGGTTCGGCGGCATTTCCATGGCCGAATATCTCGGCCTGAGATTGAGCTACATCGATTCCACCTTTACCGGC
GGCTCCTCCTATATGGCGCATGTCGGCCATGCCGCTGCTGCCATTGCCGCAGGAAAGTGCAAGGTCGCCCTCATCACGCA
AGGGGCCAAGGTGCGGGGTGTCATTCGCGGTGCCAAGCATACTGCGGATACACCGGAATTTCCCTTCGAGACGGTCTATG
GCGAAACCAATGCGGCCATTTATGCGCTGGCTGCGCGTCGGCATATGCATGAATACGGTACAACGGCAGAACAGCTCGCC
GCCGTTAAAGTTGCGGCGGCGGCCTATGCGCAACACAATCCAAATGCGCTGTTGCGCAAGCTCGTTTCAATCGACGATGT
TATGAATTCGCCAATCATTGCCGATCCCCTTCATCGGCTCGATTGCTGCGTTGTTACCGATGGCGGCGGCGCTCTTGTTC
TTGTTGCTCCTGAAATCGCGCGAAGCTTGAAGCGCCAGAGTGTCAAGCTTTTGGGTCATGCCGAAGCGATCCGGCATGGT
GGAGATGGCCCAAGCGATTTTGCCAGCACGGCAGCGGCGCTTTCAGGACCCCGTGCATTCACTGAGGCGGGCGTCAGCCC
TCGAGACGTTCGGTATGCCTCGATTTACGACTCCTTCACCATCACCGTCATCATGACTTTGGAGGATCTCGGCTTTTGCG
GGAAAGGTGAGGGTGGCGCATTTGTTGCCAGCGGCGCGCTGGGGCTTGATGGTCTGCTCCCGATCAACACGGATGGCGGC
GGCCTCTGCAACAACCATCCGGGCTACCAAGGCGGTATGGTGCGAACCATCGAAGCGGTGCGCCAGCTGCGGGGCGAAGC
CAATCCAAATACACAGGTCAAAAACTGCACCATAGCACTGGCGCACGGAACCGGCGGCGGCATGTCGCGGCACGCCAGCG
TTACGCTGGTGTTGGGTCAGGAGGACGCATAA

Upstream 100 bases:

>100_bases
TTCTGGTGGTGCCTGCGCAATGCTGGGCTGAACGATAGCCCCGAGGCCTTTGGTCGTTTGTTCACCAAACACTTGCCCGC
GTAAACATTGGGGAAATGAC

Downstream 100 bases:

>100_bases
TGGAAGACCGTCAAGAAGTGCAAGCGCTTCCCATTCCTGTGCCGGTGGTTTTCCCGGAAACAGAACCGTTCTGGACGAAT
GCCCGGAAAGGCAAGTTGCT

Product: acetyl-CoA acetyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MSIRGKAFIVGAYEHPGRNLPDHSVQQIHAECAMGALSDAGLSIKDVDGYFSNGQLGFGGISMAEYLGLRLSYIDSTFTG
GSSYMAHVGHAAAAIAAGKCKVALITQGAKVRGVIRGAKHTADTPEFPFETVYGETNAAIYALAARRHMHEYGTTAEQLA
AVKVAAAAYAQHNPNALLRKLVSIDDVMNSPIIADPLHRLDCCVVTDGGGALVLVAPEIARSLKRQSVKLLGHAEAIRHG
GDGPSDFASTAAALSGPRAFTEAGVSPRDVRYASIYDSFTITVIMTLEDLGFCGKGEGGAFVASGALGLDGLLPINTDGG
GLCNNHPGYQGGMVRTIEAVRQLRGEANPNTQVKNCTIALAHGTGGGMSRHASVTLVLGQEDA

Sequences:

>Translated_383_residues
MSIRGKAFIVGAYEHPGRNLPDHSVQQIHAECAMGALSDAGLSIKDVDGYFSNGQLGFGGISMAEYLGLRLSYIDSTFTG
GSSYMAHVGHAAAAIAAGKCKVALITQGAKVRGVIRGAKHTADTPEFPFETVYGETNAAIYALAARRHMHEYGTTAEQLA
AVKVAAAAYAQHNPNALLRKLVSIDDVMNSPIIADPLHRLDCCVVTDGGGALVLVAPEIARSLKRQSVKLLGHAEAIRHG
GDGPSDFASTAAALSGPRAFTEAGVSPRDVRYASIYDSFTITVIMTLEDLGFCGKGEGGAFVASGALGLDGLLPINTDGG
GLCNNHPGYQGGMVRTIEAVRQLRGEANPNTQVKNCTIALAHGTGGGMSRHASVTLVLGQEDA
>Mature_382_residues
SIRGKAFIVGAYEHPGRNLPDHSVQQIHAECAMGALSDAGLSIKDVDGYFSNGQLGFGGISMAEYLGLRLSYIDSTFTGG
SSYMAHVGHAAAAIAAGKCKVALITQGAKVRGVIRGAKHTADTPEFPFETVYGETNAAIYALAARRHMHEYGTTAEQLAA
VKVAAAAYAQHNPNALLRKLVSIDDVMNSPIIADPLHRLDCCVVTDGGGALVLVAPEIARSLKRQSVKLLGHAEAIRHGG
DGPSDFASTAAALSGPRAFTEAGVSPRDVRYASIYDSFTITVIMTLEDLGFCGKGEGGAFVASGALGLDGLLPINTDGGG
LCNNHPGYQGGMVRTIEAVRQLRGEANPNTQVKNCTIALAHGTGGGMSRHASVTLVLGQEDA

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI302344762, Length=239, Percent_Identity=28.0334728033473, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI302344760, Length=239, Percent_Identity=28.0334728033473, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI302344767, Length=239, Percent_Identity=28.0334728033473, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI19923233, Length=239, Percent_Identity=28.0334728033473, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI55956775, Length=199, Percent_Identity=26.1306532663317, Blast_Score=83, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17537653, Length=237, Percent_Identity=29.535864978903, Blast_Score=107, Evalue=9e-24,
Organism=Drosophila melanogaster, GI19921506, Length=392, Percent_Identity=27.0408163265306, Blast_Score=129, Evalue=5e-30,
Organism=Drosophila melanogaster, GI24585051, Length=392, Percent_Identity=27.2959183673469, Blast_Score=125, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: NA

Molecular weight: Translated: 39787; Mature: 39655

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIRGKAFIVGAYEHPGRNLPDHSVQQIHAECAMGALSDAGLSIKDVDGYFSNGQLGFGG
CCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCHHCCCCEEEECCCCCCCCCCCCCC
ISMAEYLGLRLSYIDSTFTGGSSYMAHVGHAAAAIAAGKCKVALITQGAKVRGVIRGAKH
HHHHHHHCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCEEHEEECCCC
TADTPEFPFETVYGETNAAIYALAARRHMHEYGTTAEQLAAVKVAAAAYAQHNPNALLRK
CCCCCCCCCHHHCCCCCHHEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHH
LVSIDDVMNSPIIADPLHRLDCCVVTDGGGALVLVAPEIARSLKRQSVKLLGHAEAIRHG
HHHHHHHHCCCCCCCCHHHCEEEEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCC
GDGPSDFASTAAALSGPRAFTEAGVSPRDVRYASIYDSFTITVIMTLEDLGFCGKGEGGA
CCCHHHHHHHHHHHCCCHHHHHCCCCHHHEEEEEEECCEEEEEEEEEECCCCCCCCCCCE
FVASGALGLDGLLPINTDGGGLCNNHPGYQGGMVRTIEAVRQLRGEANPNTQVKNCTIAL
EEEECCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEEE
AHGTGGGMSRHASVTLVLGQEDA
EECCCCCCCCCEEEEEEEECCCC
>Mature Secondary Structure 
SIRGKAFIVGAYEHPGRNLPDHSVQQIHAECAMGALSDAGLSIKDVDGYFSNGQLGFGG
CCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCHHCCCCEEEECCCCCCCCCCCCCC
ISMAEYLGLRLSYIDSTFTGGSSYMAHVGHAAAAIAAGKCKVALITQGAKVRGVIRGAKH
HHHHHHHCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCEEHEEECCCC
TADTPEFPFETVYGETNAAIYALAARRHMHEYGTTAEQLAAVKVAAAAYAQHNPNALLRK
CCCCCCCCCHHHCCCCCHHEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHH
LVSIDDVMNSPIIADPLHRLDCCVVTDGGGALVLVAPEIARSLKRQSVKLLGHAEAIRHG
HHHHHHHHCCCCCCCCHHHCEEEEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCC
GDGPSDFASTAAALSGPRAFTEAGVSPRDVRYASIYDSFTITVIMTLEDLGFCGKGEGGA
CCCHHHHHHHHHHHCCCHHHHHCCCCHHHEEEEEEECCEEEEEEEEEECCCCCCCCCCCE
FVASGALGLDGLLPINTDGGGLCNNHPGYQGGMVRTIEAVRQLRGEANPNTQVKNCTIAL
EEEECCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEEE
AHGTGGGMSRHASVTLVLGQEDA
EECCCCCCCCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]