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The map label for this gene is scoA [H]

Identifier: 222102732

GI number: 222102732

Start: 385841

End: 387226

Strand: Direct

Name: scoA [H]

Synonym: Avi_7413

Alternate gene names: 222102732

Gene position: 385841-387226 (Clockwise)

Preceding gene: 222102731

Following gene: 222102733

Centisome position: 61.07

GC content: 57.36

Gene sequence:

>1386_bases
TTGAACAAGGTCTTCGAAAGTACCAGTGACGCTGTTGCGGATATCAAGGACGGCGCATCGATTGCAATTGCTGGCTTTGG
CGTTGGCCATTCCTATCCCAACAGCCTGGTGTTGGCGTTGCAGGCACAAGGGGCCAAGAATCTCGCCATCATCGCGAATT
CTCTGGGGGCGGGAGGCGATTTTCGCCCGCAGATCCTGGTGCAGAACGGTCAGGTAAGCAGGCTTGTTCTGTCTTTCTCC
GTCCGCCCGGGCATGCCTTCGCCGGAAGAGGAAAAGATTGCGGCAGGCGAGATTGCACTTGAAATGGTGCCACAGGGCAT
TCTCGTGGAGAGACTGCGGGCGGCGGGTGCCGGTTTGCCTGCTTTCTATAGCCCCGTCACTGTCGGAACTCCTCTCCAGG
AGGGCAAGGAAGTACGGCGCTTTGGCGAGCGGGATTATGTTCTCGAACATGCTCTGCCCGTTGATGTTGCGCTGATCCGT
GGATACCGCGCTGACCGTTTCGGCAATGTCGAATTTCGCGGCAGCAGTGCGCATTTTCATGCCAGCTTTGCCAGGGCGGC
GAAATTGACCATCGTTGAGGTGGAGCACATTGTTGAAGCTGGCGAAATCTCGCCCGAACGCGTCGGCTTGCCGGGGATTT
TTGTTTCGCGCGTCGTGCAGACGGTCGCCAAATATCCGGCCCCTGCGGGCCGGATGGGCCGCCGTGCGCCAGAGAGTGGG
CGGGAATATTTCGGCAAACCAGCCTTAACCCGGACGAATATGGCAAAGCGTGCTGCTGCACTCTTGCCTGAAGGTGCCTA
TGTCAATCTTGGCTCAGGCCTGCCCACGCTGGTCGCTGCGCACACACAGGACAAATCCATCTTTCTTCACGCGGAGAATG
GGGCTCTCGGTTACGATCTGCTGCAGGATCCTGCCCAATTCGACGTCGATTTTTTCGATGCGGCAGGAAACTTCATCAAA
ATGCGACCCGGTGGTGCCGTGTTTGACAGCGTAGCCTCCTTCGAAATTGCGCGATCAGGAAAGCTGTCGGCGATCCTTTT
GGGGGCCTATCAGGTCAGTGAAAAGGGTGATCTGGCCAATTGGGCCGTACCGGGCCAGTCCGGTGGGGGCATTGGCGGCG
CTATGGATCTCGCGTCGTCCGGGAGCAAGGTTATCGTTCTCATGGAGCATTGCGATGGCAAGGGTAAGCCAAAGTTTGTG
CGTAAATGTTCCTATCCGCTCACCGCGCTTGCGTGTGTCGATACGGTGGTAACTGACCTGGCGCTGCTGGTGCGTCAGGG
AAATAGCTTCGAGGTTACCGCGATTGCTGAAGGATTCACGCCAGATGAAATTCGTGCGCTAACCCCGATCGACATCACGT
TTGCGCAATCACTCGAGGTGATGTGA

Upstream 100 bases:

>100_bases
AGGTCGTGTTTCACAATAGCAGCGACGCCACGGCTCTCCCACGATTCACACCGGCCTGATTTGCCGAATTCAATTTTAGA
TGTAGTGGAAGGAGGAGGCA

Downstream 100 bases:

>100_bases
GCGGCCTGATGTCGCCATTGGGTCGGGATCAGGCAGTGGCGTGAACAAAGGTGGGGACGATTTTTTTTAATCTTCCGTTT
CGTTCCGGGACGGAAATAAC

Product: ScoB

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MNKVFESTSDAVADIKDGASIAIAGFGVGHSYPNSLVLALQAQGAKNLAIIANSLGAGGDFRPQILVQNGQVSRLVLSFS
VRPGMPSPEEEKIAAGEIALEMVPQGILVERLRAAGAGLPAFYSPVTVGTPLQEGKEVRRFGERDYVLEHALPVDVALIR
GYRADRFGNVEFRGSSAHFHASFARAAKLTIVEVEHIVEAGEISPERVGLPGIFVSRVVQTVAKYPAPAGRMGRRAPESG
REYFGKPALTRTNMAKRAAALLPEGAYVNLGSGLPTLVAAHTQDKSIFLHAENGALGYDLLQDPAQFDVDFFDAAGNFIK
MRPGGAVFDSVASFEIARSGKLSAILLGAYQVSEKGDLANWAVPGQSGGGIGGAMDLASSGSKVIVLMEHCDGKGKPKFV
RKCSYPLTALACVDTVVTDLALLVRQGNSFEVTAIAEGFTPDEIRALTPIDITFAQSLEVM

Sequences:

>Translated_461_residues
MNKVFESTSDAVADIKDGASIAIAGFGVGHSYPNSLVLALQAQGAKNLAIIANSLGAGGDFRPQILVQNGQVSRLVLSFS
VRPGMPSPEEEKIAAGEIALEMVPQGILVERLRAAGAGLPAFYSPVTVGTPLQEGKEVRRFGERDYVLEHALPVDVALIR
GYRADRFGNVEFRGSSAHFHASFARAAKLTIVEVEHIVEAGEISPERVGLPGIFVSRVVQTVAKYPAPAGRMGRRAPESG
REYFGKPALTRTNMAKRAAALLPEGAYVNLGSGLPTLVAAHTQDKSIFLHAENGALGYDLLQDPAQFDVDFFDAAGNFIK
MRPGGAVFDSVASFEIARSGKLSAILLGAYQVSEKGDLANWAVPGQSGGGIGGAMDLASSGSKVIVLMEHCDGKGKPKFV
RKCSYPLTALACVDTVVTDLALLVRQGNSFEVTAIAEGFTPDEIRALTPIDITFAQSLEVM
>Mature_461_residues
MNKVFESTSDAVADIKDGASIAIAGFGVGHSYPNSLVLALQAQGAKNLAIIANSLGAGGDFRPQILVQNGQVSRLVLSFS
VRPGMPSPEEEKIAAGEIALEMVPQGILVERLRAAGAGLPAFYSPVTVGTPLQEGKEVRRFGERDYVLEHALPVDVALIR
GYRADRFGNVEFRGSSAHFHASFARAAKLTIVEVEHIVEAGEISPERVGLPGIFVSRVVQTVAKYPAPAGRMGRRAPESG
REYFGKPALTRTNMAKRAAALLPEGAYVNLGSGLPTLVAAHTQDKSIFLHAENGALGYDLLQDPAQFDVDFFDAAGNFIK
MRPGGAVFDSVASFEIARSGKLSAILLGAYQVSEKGDLANWAVPGQSGGGIGGAMDLASSGSKVIVLMEHCDGKGKPKFV
RKCSYPLTALACVDTVVTDLALLVRQGNSFEVTAIAEGFTPDEIRALTPIDITFAQSLEVM

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG2057

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=482, Percent_Identity=36.3070539419087, Blast_Score=288, Evalue=5e-78,
Organism=Homo sapiens, GI11545841, Length=480, Percent_Identity=37.7083333333333, Blast_Score=287, Evalue=1e-77,
Organism=Escherichia coli, GI1788552, Length=210, Percent_Identity=40.4761904761905, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1788551, Length=219, Percent_Identity=34.2465753424658, Blast_Score=131, Evalue=9e-32,
Organism=Escherichia coli, GI1787985, Length=416, Percent_Identity=26.4423076923077, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17531517, Length=487, Percent_Identity=35.523613963039, Blast_Score=283, Evalue=9e-77,
Organism=Drosophila melanogaster, GI24655794, Length=483, Percent_Identity=34.9896480331263, Blast_Score=284, Evalue=8e-77,
Organism=Drosophila melanogaster, GI21358325, Length=483, Percent_Identity=34.9896480331263, Blast_Score=284, Evalue=8e-77,

Paralogues:

None

Copy number: 369 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 48725; Mature: 48725

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKVFESTSDAVADIKDGASIAIAGFGVGHSYPNSLVLALQAQGAKNLAIIANSLGAGGD
CCCCCCCCCHHHHHHCCCCEEEEEEECCCCCCCCEEEEEEECCCCCCEEEEEECCCCCCC
FRPQILVQNGQVSRLVLSFSVRPGMPSPEEEKIAAGEIALEMVPQGILVERLRAAGAGLP
CCCEEEEECCCEEEEEEEEEECCCCCCCCHHHHHHHHHEEECCCCHHHHHHHHHCCCCCC
AFYSPVTVGTPLQEGKEVRRFGERDYVLEHALPVDVALIRGYRADRFGNVEFRGSSAHFH
CCCCCCCCCCCHHHHHHHHHCCCCCCHHHHCCCHHHHHHCCCCCCCCCCEEEECCCCEEH
ASFARAAKLTIVEVEHIVEAGEISPERVGLPGIFVSRVVQTVAKYPAPAGRMGRRAPESG
HHHHHHHEEEEEEHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
REYFGKPALTRTNMAKRAAALLPEGAYVNLGSGLPTLVAAHTQDKSIFLHAENGALGYDL
HHHCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCEEEEEECCCCEEEEEECCCCCCHHH
LQDPAQFDVDFFDAAGNFIKMRPGGAVFDSVASFEIARSGKLSAILLGAYQVSEKGDLAN
HCCHHHCCCEEECCCCCEEEECCCCHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCE
WAVPGQSGGGIGGAMDLASSGSKVIVLMEHCDGKGKPKFVRKCSYPLTALACVDTVVTDL
EECCCCCCCCCCHHHHHCCCCCEEEEEEECCCCCCCCHHHHHCCCCHHHHHHHHHHHHHH
ALLVRQGNSFEVTAIAEGFTPDEIRALTPIDITFAQSLEVM
HHHHHCCCCEEEEEEECCCCHHHHEECCCCEEEECCCCCCC
>Mature Secondary Structure
MNKVFESTSDAVADIKDGASIAIAGFGVGHSYPNSLVLALQAQGAKNLAIIANSLGAGGD
CCCCCCCCCHHHHHHCCCCEEEEEEECCCCCCCCEEEEEEECCCCCCEEEEEECCCCCCC
FRPQILVQNGQVSRLVLSFSVRPGMPSPEEEKIAAGEIALEMVPQGILVERLRAAGAGLP
CCCEEEEECCCEEEEEEEEEECCCCCCCCHHHHHHHHHEEECCCCHHHHHHHHHCCCCCC
AFYSPVTVGTPLQEGKEVRRFGERDYVLEHALPVDVALIRGYRADRFGNVEFRGSSAHFH
CCCCCCCCCCCHHHHHHHHHCCCCCCHHHHCCCHHHHHHCCCCCCCCCCEEEECCCCEEH
ASFARAAKLTIVEVEHIVEAGEISPERVGLPGIFVSRVVQTVAKYPAPAGRMGRRAPESG
HHHHHHHEEEEEEHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
REYFGKPALTRTNMAKRAAALLPEGAYVNLGSGLPTLVAAHTQDKSIFLHAENGALGYDL
HHHCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCEEEEEECCCCEEEEEECCCCCCHHH
LQDPAQFDVDFFDAAGNFIKMRPGGAVFDSVASFEIARSGKLSAILLGAYQVSEKGDLAN
HCCHHHCCCEEECCCCCEEEECCCCHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCE
WAVPGQSGGGIGGAMDLASSGSKVIVLMEHCDGKGKPKFVRKCSYPLTALACVDTVVTDL
EECCCCCCCCCCHHHHHCCCCCEEEEEEECCCCCCCCHHHHHCCCCHHHHHHHHHHHHHH
ALLVRQGNSFEVTAIAEGFTPDEIRALTPIDITFAQSLEVM
HHHHHCCCCEEEEEEECCCCHHHHEECCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377 [H]