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The map label for this gene is mhpR [H]

Identifier: 222102724

GI number: 222102724

Start: 375396

End: 376295

Strand: Direct

Name: mhpR [H]

Synonym: Avi_7402

Alternate gene names: 222102724

Gene position: 375396-376295 (Clockwise)

Preceding gene: 222102723

Following gene: 222102725

Centisome position: 59.42

GC content: 54.11

Gene sequence:

>900_bases
ATGTTTTCAAAAAAAGTCAAATGGGAGGAGACCATGACTTACAAAAGCATCAGAGCACTGGAGCGCGGTATAGACGTGTT
GCAGTACCTCAATACGGTTAAAGGAGCTGCACCGCCGGAGATTGCTGAAAACGTCAATCTTCCACGTCCTACAGTCCATC
GAATTCTTGAAACGCTGAGCGAACTCAACTTGGTCTATCGCAGTCAGCTTGGAGACGAATATCGTCTTAGCTCTGGCGTG
CAGCGATTGGCGGGCAACAGGTCATCCGTGCGGCTGAATTGGATTGATGAAATCGCCTTGCCAGCACTGCTCGAACTCAC
ATCGGAGATCATTTGGCCGTCGGACATTGCTGTTTGCCACAAAGCTGCAATGATCATCCAGGGAACCACACATCGCATCA
GTCCCATGTCGTGCGATGTCGGAATGGTGGGCAATCGGCGTTCCATGCTGATGAGCCCGCTGGGCCGTGCCTATCTCAGT
CACTGCCCGGATGACGAGCTAAAGTCTATTCTTTGCGCTCTGAACGCGTCATCGGCATCTGAGGATAAGGGCGCGCGCGA
TCGCGCTTTCATTAAGGAGATTATTGAAACGGGTCGTCGTGATGGTGTTAGCGCCTGCAACGAACGACCGCACCCGCGAT
GCGCCAGCCTTGCTGCACCCATTCGCTTGAATGGGAAGGTACTTGCCTGCATGAACGTTGTCTGGCGGGCCAATATGCTC
ACGATTGAAGACGCAATGGATCAGATACGTGACCCATTGCTCGCGACGCGTGACCGGATCGAAGCTCAACTCCACGAACA
GTTCGCACGACCGGCGCTGGGCTCGACAAGCTTCCCTGAAACATACACCCTGCGGACGGGAACGCGTGATCGCTTGCCTC
ACAGTCTAGCCCTTGCTTGA

Upstream 100 bases:

>100_bases
GAAAATCCAATGAATTCGCGGGCAAAGCGTCGGCGATGGCAGGCGAATGAGCGGCGCTCGTCGATATCTGACAGGTTTGA
CAATGCATAGAGCGAGGAGC

Downstream 100 bases:

>100_bases
TTGCATCAATATGGCCCGCCCACGAGGGGTTTCCTTCGTGGGCGGCCCCTATTGGCTCAGAGGAAGGACAAAGCATGACC
AAAACACTTGGATTTCTTGG

Product: Transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MFSKKVKWEETMTYKSIRALERGIDVLQYLNTVKGAAPPEIAENVNLPRPTVHRILETLSELNLVYRSQLGDEYRLSSGV
QRLAGNRSSVRLNWIDEIALPALLELTSEIIWPSDIAVCHKAAMIIQGTTHRISPMSCDVGMVGNRRSMLMSPLGRAYLS
HCPDDELKSILCALNASSASEDKGARDRAFIKEIIETGRRDGVSACNERPHPRCASLAAPIRLNGKVLACMNVVWRANML
TIEDAMDQIRDPLLATRDRIEAQLHEQFARPALGSTSFPETYTLRTGTRDRLPHSLALA

Sequences:

>Translated_299_residues
MFSKKVKWEETMTYKSIRALERGIDVLQYLNTVKGAAPPEIAENVNLPRPTVHRILETLSELNLVYRSQLGDEYRLSSGV
QRLAGNRSSVRLNWIDEIALPALLELTSEIIWPSDIAVCHKAAMIIQGTTHRISPMSCDVGMVGNRRSMLMSPLGRAYLS
HCPDDELKSILCALNASSASEDKGARDRAFIKEIIETGRRDGVSACNERPHPRCASLAAPIRLNGKVLACMNVVWRANML
TIEDAMDQIRDPLLATRDRIEAQLHEQFARPALGSTSFPETYTLRTGTRDRLPHSLALA
>Mature_299_residues
MFSKKVKWEETMTYKSIRALERGIDVLQYLNTVKGAAPPEIAENVNLPRPTVHRILETLSELNLVYRSQLGDEYRLSSGV
QRLAGNRSSVRLNWIDEIALPALLELTSEIIWPSDIAVCHKAAMIIQGTTHRISPMSCDVGMVGNRRSMLMSPLGRAYLS
HCPDDELKSILCALNASSASEDKGARDRAFIKEIIETGRRDGVSACNERPHPRCASLAAPIRLNGKVLACMNVVWRANML
TIEDAMDQIRDPLLATRDRIEAQLHEQFARPALGSTSFPETYTLRTGTRDRLPHSLALA

Specific function: Activator of the mhpRABCDEF operon coding for components of the 3-hydroxyphenylpropionate degradation pathway [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI145693096, Length=263, Percent_Identity=33.4600760456274, Blast_Score=128, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 33331; Mature: 33331

Theoretical pI: Translated: 8.29; Mature: 8.29

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSKKVKWEETMTYKSIRALERGIDVLQYLNTVKGAAPPEIAENVNLPRPTVHRILETLS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHH
ELNLVYRSQLGDEYRLSSGVQRLAGNRSSVRLNWIDEIALPALLELTSEIIWPSDIAVCH
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHH
KAAMIIQGTTHRISPMSCDVGMVGNRRSMLMSPLGRAYLSHCPDDELKSILCALNASSAS
HHHHHEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC
EDKGARDRAFIKEIIETGRRDGVSACNERPHPRCASLAAPIRLNGKVLACMNVVWRANML
CCCCCHHHHHHHHHHHCCCCCCHHHHCCCCCCCHHHHCCCEEECCCHHHHHHHHHHCCHH
TIEDAMDQIRDPLLATRDRIEAQLHEQFARPALGSTSFPETYTLRTGTRDRLPHSLALA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHCCCHHCCC
>Mature Secondary Structure
MFSKKVKWEETMTYKSIRALERGIDVLQYLNTVKGAAPPEIAENVNLPRPTVHRILETLS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHH
ELNLVYRSQLGDEYRLSSGVQRLAGNRSSVRLNWIDEIALPALLELTSEIIWPSDIAVCH
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHH
KAAMIIQGTTHRISPMSCDVGMVGNRRSMLMSPLGRAYLSHCPDDELKSILCALNASSAS
HHHHHEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC
EDKGARDRAFIKEIIETGRRDGVSACNERPHPRCASLAAPIRLNGKVLACMNVVWRANML
CCCCCHHHHHHHHHHHCCCCCCHHHHCCCCCCCHHHHCCCEEECCCHHHHHHHHHHCCHH
TIEDAMDQIRDPLLATRDRIEAQLHEQFARPALGSTSFPETYTLRTGTRDRLPHSLALA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]