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The map label for this gene is rbtR [H]

Identifier: 222102705

GI number: 222102705

Start: 354596

End: 355639

Strand: Direct

Name: rbtR [H]

Synonym: Avi_7379

Alternate gene names: 222102705

Gene position: 354596-355639 (Clockwise)

Preceding gene: 222102699

Following gene: 222102706

Centisome position: 56.13

GC content: 54.89

Gene sequence:

>1044_bases
GTGAATCAGAAAAAAACTGCCAAGAAGACGACGATCTATGATCTGGCCGAGCTTGCGGGCACATCGGCCAGCGCTGTGAG
TGCTGTTTTGAACGGCAATTGGAAGAAGCGCCGGATCAGCACGCAATTGGCGGAAAAAATCAGACGGATTGCTGAAGAGC
AAGGCTATGCGCTCAACATGCAGGCCAGCCTGCTGCGCCGGGAAAAATCCCAGATCATCGGCATGATCGTCCCTAAGTAT
GACAACCGTTATTTTGGCTCGATCGTAGAGACCTTCGAGGACATGGCGCGCTCGCGCGGCCTTTTCCCGATTATCACCTG
CACGCGACGTGACCCGGAGCTTGAAGTAGAGGCCGCACGGACTCTGCTGTCCTATCAAGTGGAATGGCTGGTTTCGACCG
GAGCAACCAACCCCGACCGGATCACCGAAATATGCACCTCCGCCGGCGCGCGCAGCATTAATCTCGACCTGCCGGGAACA
GCAGCACCTTCCGTTATTTCGGATAATTTTGCAGGGGCGCGGGAATTGACCCGTCGTATTCTAAAAAATTGCCACAGCAA
GACCGGCAAGGCCGCACCCCTGCTGTTTGTTGGCGGGCGCGCCACTGATCACAACACCTTGGAGCGGGTGCGCGGTTTTC
GGGCAGCCCATCAGGATATGGGCGTTCCGATCGATGAACGCCACATACTCACCTGCGGATACGCCCCGGAAAAAGCAGAA
AAAGCTTTGCAAACATTGGCGATGGTTGAAGGCGAAATTCCGGGCGGAATGTTTGTAAACTCCACCATCTCTCTGGAAGG
CGTCATGCAGTGGCTCAAGACCTCCGGCTATGTCGCGGATCGGCTACCAGCGATGGGCTGTTTCGACTGGGATCCCTTTG
TGGCGCTTTTGGGTGGCGACATCGAAATGGTGCGCCAGGATGTCGATGGCATGCTCAAGGCGGTTTTTGAGATTATCGAT
ACAGGAATATCACAGACTACATTCATTGAGGTGCCGCCGTTATTCTCTGGGCAAGCAAATGCTGAGGTGAAAATCACCCC
TTAA

Upstream 100 bases:

>100_bases
CCAACCAACTTCATCGATTGAGCAACGTTGCTCAATCGATGACGCAAGAATTGCCATCTTCTGACTTTGATGTCAAGTTG
GGTTTCAACGGGAGGCGCTT

Downstream 100 bases:

>100_bases
ACTCTGAACTGACCGACTGCCCGGATACCGTTCGATCAGGCAAACTAGCACACCTGTACGAGTTGACCTTACGCCGCCTA
TGCCGCTGAAGTTACGCGGG

Product: transcriptional regulator LacI family

Products: NA

Alternate protein names: Rbt operon repressor [H]

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MNQKKTAKKTTIYDLAELAGTSASAVSAVLNGNWKKRRISTQLAEKIRRIAEEQGYALNMQASLLRREKSQIIGMIVPKY
DNRYFGSIVETFEDMARSRGLFPIITCTRRDPELEVEAARTLLSYQVEWLVSTGATNPDRITEICTSAGARSINLDLPGT
AAPSVISDNFAGARELTRRILKNCHSKTGKAAPLLFVGGRATDHNTLERVRGFRAAHQDMGVPIDERHILTCGYAPEKAE
KALQTLAMVEGEIPGGMFVNSTISLEGVMQWLKTSGYVADRLPAMGCFDWDPFVALLGGDIEMVRQDVDGMLKAVFEIID
TGISQTTFIEVPPLFSGQANAEVKITP

Sequences:

>Translated_347_residues
MNQKKTAKKTTIYDLAELAGTSASAVSAVLNGNWKKRRISTQLAEKIRRIAEEQGYALNMQASLLRREKSQIIGMIVPKY
DNRYFGSIVETFEDMARSRGLFPIITCTRRDPELEVEAARTLLSYQVEWLVSTGATNPDRITEICTSAGARSINLDLPGT
AAPSVISDNFAGARELTRRILKNCHSKTGKAAPLLFVGGRATDHNTLERVRGFRAAHQDMGVPIDERHILTCGYAPEKAE
KALQTLAMVEGEIPGGMFVNSTISLEGVMQWLKTSGYVADRLPAMGCFDWDPFVALLGGDIEMVRQDVDGMLKAVFEIID
TGISQTTFIEVPPLFSGQANAEVKITP
>Mature_347_residues
MNQKKTAKKTTIYDLAELAGTSASAVSAVLNGNWKKRRISTQLAEKIRRIAEEQGYALNMQASLLRREKSQIIGMIVPKY
DNRYFGSIVETFEDMARSRGLFPIITCTRRDPELEVEAARTLLSYQVEWLVSTGATNPDRITEICTSAGARSINLDLPGT
AAPSVISDNFAGARELTRRILKNCHSKTGKAAPLLFVGGRATDHNTLERVRGFRAAHQDMGVPIDERHILTCGYAPEKAE
KALQTLAMVEGEIPGGMFVNSTISLEGVMQWLKTSGYVADRLPAMGCFDWDPFVALLGGDIEMVRQDVDGMLKAVFEIID
TGISQTTFIEVPPLFSGQANAEVKITP

Specific function: Repressor for the genes of the ribitol operon. Binds D- ribulose as an inducer [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787906, Length=275, Percent_Identity=29.4545454545455, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1786268, Length=314, Percent_Identity=26.4331210191083, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1788474, Length=181, Percent_Identity=29.8342541436464, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI48994940, Length=219, Percent_Identity=25.1141552511416, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789202, Length=239, Percent_Identity=25.9414225941423, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 38116; Mature: 38116

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQKKTAKKTTIYDLAELAGTSASAVSAVLNGNWKKRRISTQLAEKIRRIAEEQGYALNM
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEECH
QASLLRREKSQIIGMIVPKYDNRYFGSIVETFEDMARSRGLFPIITCTRRDPELEVEAAR
HHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHH
TLLSYQVEWLVSTGATNPDRITEICTSAGARSINLDLPGTAAPSVISDNFAGARELTRRI
HHHHHHHHHHEECCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCHHHCCCCCHHHHHHHH
LKNCHSKTGKAAPLLFVGGRATDHNTLERVRGFRAAHQDMGVPIDERHILTCGYAPEKAE
HHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHH
KALQTLAMVEGEIPGGMFVNSTISLEGVMQWLKTSGYVADRLPAMGCFDWDPFVALLGGD
HHHHHHHHHCCCCCCCEEEECEECHHHHHHHHHHCCCHHHCCCCCCCCCCCHHHHHHCCC
IEMVRQDVDGMLKAVFEIIDTGISQTTFIEVPPLFSGQANAEVKITP
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCEEEECC
>Mature Secondary Structure
MNQKKTAKKTTIYDLAELAGTSASAVSAVLNGNWKKRRISTQLAEKIRRIAEEQGYALNM
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEECH
QASLLRREKSQIIGMIVPKYDNRYFGSIVETFEDMARSRGLFPIITCTRRDPELEVEAAR
HHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHH
TLLSYQVEWLVSTGATNPDRITEICTSAGARSINLDLPGTAAPSVISDNFAGARELTRRI
HHHHHHHHHHEECCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCHHHCCCCCHHHHHHHH
LKNCHSKTGKAAPLLFVGGRATDHNTLERVRGFRAAHQDMGVPIDERHILTCGYAPEKAE
HHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHH
KALQTLAMVEGEIPGGMFVNSTISLEGVMQWLKTSGYVADRLPAMGCFDWDPFVALLGGD
HHHHHHHHHCCCCCCCEEEECEECHHHHHHHHHHCCCHHHCCCCCCCCCCCHHHHHHCCC
IEMVRQDVDGMLKAVFEIIDTGISQTTFIEVPPLFSGQANAEVKITP
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3891331 [H]