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The map label for this gene is fecD [H]

Identifier: 222102635

GI number: 222102635

Start: 246700

End: 247683

Strand: Reverse

Name: fecD [H]

Synonym: Avi_7289

Alternate gene names: 222102635

Gene position: 247683-246700 (Counterclockwise)

Preceding gene: 222102636

Following gene: 222102634

Centisome position: 39.2

GC content: 61.79

Gene sequence:

>984_bases
ATGATCCGGGTTTTCTTCGTCCTGATACTTCTGCTCACATTTCTCGTGGCGGCAAGTCTCGCTTTTGGTGACGTGTCCTT
GGGCTGGCAAGAACTCTACGATGTGCTGATGGGCACGGGCCGTGCACAGTTGCAGAGCGAAATGATTGTTTGGGATCTGC
GTCTTCCACGCGTTCTTCTGGCGCTCCTTGTTGGCGTCGCACTCGCGCTCGCCGGAACGATCAGCATTGCCATCATGCGC
AATCCGCTTGCTGATCCGGGCGTTCTGGGCATCAACAGCGGTGCGGCTGCTGCGGCCATGGCTGTCATTGTATTGATCAG
TGATCCACCTGTGGCGCTTCTGCAAGTGGCAGGCTTCGTGGGTGCCAGCGCCATGGCCCTTGCCGTTTTTGCACTCGCCT
GGCGCAGCGGCACCTCCTCGCTGCGTATCATCCTGATCGGCATCGGGCTTTCCGCCCTCGCCTCCGCCGGTACTACTTTC
CTGTCAGCCTTCGGCGACATTGGCGACGTTCAGCGGGCGCTGGTATGGTTAGCCGGCAGCGTCTACGACGCCAACATGGT
CAAGGTGCGGATGCTTGCGCTCTGGCTCATCGTGCCGATCGCACTCACACTTCTCGCCGCGCGGGAACTCGACCTCATCC
GCTTCGGTGACAATAGTGCAAGGAGCCTCGGCCAGCCCGTCGATCGTATACGGGGCCTGATGATCCTGCTGGTGACCCTA
CTCTCTGGTGCCGCCATTGCCGTGTCGGGTCTCATCGGCTTTGTCGGCCTTGTCGCGCCGCATATCGCGCGCCGGCTGGT
AGGAGTCTCCCATGCCCGGATCCTCCCGGTCGCAGCCCTCGTCGGTGCCTGCCTCGTCGTCGCCGCGGATCTCATCGGTC
GTGTCATCCTGGCCCCAGCGCAGCTCCCGGCCGGAATCGTGACCGGACTCGTCGGTGCTCCCTTCTTTGGCTATATTCTC
TGGAGACGTCGCCATGACCACTGA

Upstream 100 bases:

>100_bases
TGGTGTTTGGAAGCCAAAGCTTTCCCGTCGGTGTCACCATTGCGTTGATCGGCGCGCCGTTTTTCCTCTATCTCGCCCGC
ACGCGGCTGAGGGACGGCGC

Downstream 100 bases:

>100_bases
TCTGCAAGGCGGTCCCAGGATCATCAGCAATGGCGTCGACATTGCCTATGGCGATCGCCGCATCGTCGAAAATCTCGATC
TTGCGATCCCGCAACAGCGC

Product: ABC transporter

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MIRVFFVLILLLTFLVAASLAFGDVSLGWQELYDVLMGTGRAQLQSEMIVWDLRLPRVLLALLVGVALALAGTISIAIMR
NPLADPGVLGINSGAAAAAMAVIVLISDPPVALLQVAGFVGASAMALAVFALAWRSGTSSLRIILIGIGLSALASAGTTF
LSAFGDIGDVQRALVWLAGSVYDANMVKVRMLALWLIVPIALTLLAARELDLIRFGDNSARSLGQPVDRIRGLMILLVTL
LSGAAIAVSGLIGFVGLVAPHIARRLVGVSHARILPVAALVGACLVVAADLIGRVILAPAQLPAGIVTGLVGAPFFGYIL
WRRRHDH

Sequences:

>Translated_327_residues
MIRVFFVLILLLTFLVAASLAFGDVSLGWQELYDVLMGTGRAQLQSEMIVWDLRLPRVLLALLVGVALALAGTISIAIMR
NPLADPGVLGINSGAAAAAMAVIVLISDPPVALLQVAGFVGASAMALAVFALAWRSGTSSLRIILIGIGLSALASAGTTF
LSAFGDIGDVQRALVWLAGSVYDANMVKVRMLALWLIVPIALTLLAARELDLIRFGDNSARSLGQPVDRIRGLMILLVTL
LSGAAIAVSGLIGFVGLVAPHIARRLVGVSHARILPVAALVGACLVVAADLIGRVILAPAQLPAGIVTGLVGAPFFGYIL
WRRRHDH
>Mature_327_residues
MIRVFFVLILLLTFLVAASLAFGDVSLGWQELYDVLMGTGRAQLQSEMIVWDLRLPRVLLALLVGVALALAGTISIAIMR
NPLADPGVLGINSGAAAAAMAVIVLISDPPVALLQVAGFVGASAMALAVFALAWRSGTSSLRIILIGIGLSALASAGTTF
LSAFGDIGDVQRALVWLAGSVYDANMVKVRMLALWLIVPIALTLLAARELDLIRFGDNSARSLGQPVDRIRGLMILLVTL
LSGAAIAVSGLIGFVGLVAPHIARRLVGVSHARILPVAALVGACLVVAADLIGRVILAPAQLPAGIVTGLVGAPFFGYIL
WRRRHDH

Specific function: Part of the ABC transporter complex yfiYZ/yfhA/yusV involved in import of the iron-hydroxamate siderophores schizokinen, arthrobactin and corprogen (Probable) [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=308, Percent_Identity=37.3376623376623, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1786347, Length=318, Percent_Identity=34.5911949685535, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI1790741, Length=289, Percent_Identity=36.6782006920415, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1786804, Length=309, Percent_Identity=35.9223300970874, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1788004, Length=279, Percent_Identity=35.4838709677419, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1786805, Length=288, Percent_Identity=35.7638888888889, Blast_Score=117, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 34124; Mature: 34124

Theoretical pI: Translated: 11.03; Mature: 11.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRVFFVLILLLTFLVAASLAFGDVSLGWQELYDVLMGTGRAQLQSEMIVWDLRLPRVLL
CHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHEEECHHHHHHH
ALLVGVALALAGTISIAIMRNPLADPGVLGINSGAAAAAMAVIVLISDPPVALLQVAGFV
HHHHHHHHHHHHHHHHEEEECCCCCCCCEECCCCHHHHHHHHHEEECCCCHHHHHHHHHH
GASAMALAVFALAWRSGTSSLRIILIGIGLSALASAGTTFLSAFGDIGDVQRALVWLAGS
HHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
VYDANMVKVRMLALWLIVPIALTLLAARELDLIRFGDNSARSLGQPVDRIRGLMILLVTL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHCCHHHHHHHHHHHHHHH
LSGAAIAVSGLIGFVGLVAPHIARRLVGVSHARILPVAALVGACLVVAADLIGRVILAPA
HCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QLPAGIVTGLVGAPFFGYILWRRRHDH
CCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIRVFFVLILLLTFLVAASLAFGDVSLGWQELYDVLMGTGRAQLQSEMIVWDLRLPRVLL
CHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHEEECHHHHHHH
ALLVGVALALAGTISIAIMRNPLADPGVLGINSGAAAAAMAVIVLISDPPVALLQVAGFV
HHHHHHHHHHHHHHHHEEEECCCCCCCCEECCCCHHHHHHHHHEEECCCCHHHHHHHHHH
GASAMALAVFALAWRSGTSSLRIILIGIGLSALASAGTTFLSAFGDIGDVQRALVWLAGS
HHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
VYDANMVKVRMLALWLIVPIALTLLAARELDLIRFGDNSARSLGQPVDRIRGLMILLVTL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHCCHHHHHHHHHHHHHHH
LSGAAIAVSGLIGFVGLVAPHIARRLVGVSHARILPVAALVGACLVVAADLIGRVILAPA
HCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QLPAGIVTGLVGAPFFGYILWRRRHDH
CCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]