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The map label for this gene is fecC [H]

Identifier: 222102636

GI number: 222102636

Start: 247680

End: 248708

Strand: Reverse

Name: fecC [H]

Synonym: Avi_7290

Alternate gene names: 222102636

Gene position: 248708-247680 (Counterclockwise)

Preceding gene: 222102637

Following gene: 222102635

Centisome position: 39.37

GC content: 60.74

Gene sequence:

>1029_bases
ATGACCGACCGCACGGCTGGCTATATTGCAGAAACCGATGTAGGACGAGTGCTTGCGCTTGCCGCATTACTCTGTCTGCT
CATGCTTGCCACCGTGATCGCCATCTCACTGGGTGCGGCGATGATGCCGCCCGCCAAAGTCATCTCGGCACTCTTCGCAT
CCGAGACGTCGCGGGATCACCTGATCGTCATGACCATTCGCCTGCCACGTGCGCTTGCGGCGCTGCTGGCAGGTAGCGCA
CTGGCTGTCTCTGGTGCCATCATGCAGGCGGTGACAAACAATCCCCTCGCCTCACCGGACCTGCTCGGCATCAACGCAGG
CGCAGCCTTTGCAGTCGTCTCCGTCATGGCCATTTTCGGTGCCGGTATCGGCGACATCTACGTTTGGTTTGCTTTTCTCG
GCGCAGCCATCGCCGCGACCGTTGTCTATGCGCTGGGTTCGATGGGAATGGTGGGGCAATCCCCCCTCAGGCTCGTGCTG
GCGGGAGCTATCGTTGCGACCTTCCTGACCTCTGTGACCACCGTTATGCTGATCTTTGACCAGAGTACTCTTGATGCCGT
GCGCCTCTGGACCGCAGGCTCGGTGACGGGACGAAACATCGAACAGGTCAAGACCGTTGCGCCCTATATCATTGCCGGGC
TGATCGCTGCCCTGCCCTTTGGCCGTCATCTGACGACAATCAGCCTTGGCGCGGATACGTCGCGCGCGCTCGGCCAGAAC
CCAATCGTCTGGCGGGGCCTATCGGTCGCGGTGGTCATTTTGCTTGCCGGTGGTGCCGTCGCACTTGCCGGACCGATCGG
CTTCGTCGGGCTTGTCGTGCCCCATGTTGCAAGGATGTGCATCGGCGTTGACTATCGCTGGATCATTCCTTTTTCAGCAC
TCGGCGGTGCGTTGCTGGTGATCGTGGCAGATACGGTCGGACGATTGGTGTTTGGAAGCCAAAGCTTTCCCGTCGGTGTC
ACCATTGCGTTGATCGGCGCGCCGTTTTTCCTCTATCTCGCCCGCACGCGGCTGAGGGACGGCGCATGA

Upstream 100 bases:

>100_bases
GCGCCTATCGGGTCGACCGCGGCCCTTGGCAGAGCTTCTACGGCATCAGCTCGGCAAACCGTATCCTCGACGATGTCGAA
CGCTTCATCCTGACGACCCC

Downstream 100 bases:

>100_bases
TCCGGGTTTTCTTCGTCCTGATACTTCTGCTCACATTTCTCGTGGCGGCAAGTCTCGCTTTTGGTGACGTGTCCTTGGGC
TGGCAAGAACTCTACGATGT

Product: ABC transporter membrane spanning protein (iron(III) dicitrate)

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MTDRTAGYIAETDVGRVLALAALLCLLMLATVIAISLGAAMMPPAKVISALFASETSRDHLIVMTIRLPRALAALLAGSA
LAVSGAIMQAVTNNPLASPDLLGINAGAAFAVVSVMAIFGAGIGDIYVWFAFLGAAIAATVVYALGSMGMVGQSPLRLVL
AGAIVATFLTSVTTVMLIFDQSTLDAVRLWTAGSVTGRNIEQVKTVAPYIIAGLIAALPFGRHLTTISLGADTSRALGQN
PIVWRGLSVAVVILLAGGAVALAGPIGFVGLVVPHVARMCIGVDYRWIIPFSALGGALLVIVADTVGRLVFGSQSFPVGV
TIALIGAPFFLYLARTRLRDGA

Sequences:

>Translated_342_residues
MTDRTAGYIAETDVGRVLALAALLCLLMLATVIAISLGAAMMPPAKVISALFASETSRDHLIVMTIRLPRALAALLAGSA
LAVSGAIMQAVTNNPLASPDLLGINAGAAFAVVSVMAIFGAGIGDIYVWFAFLGAAIAATVVYALGSMGMVGQSPLRLVL
AGAIVATFLTSVTTVMLIFDQSTLDAVRLWTAGSVTGRNIEQVKTVAPYIIAGLIAALPFGRHLTTISLGADTSRALGQN
PIVWRGLSVAVVILLAGGAVALAGPIGFVGLVVPHVARMCIGVDYRWIIPFSALGGALLVIVADTVGRLVFGSQSFPVGV
TIALIGAPFFLYLARTRLRDGA
>Mature_341_residues
TDRTAGYIAETDVGRVLALAALLCLLMLATVIAISLGAAMMPPAKVISALFASETSRDHLIVMTIRLPRALAALLAGSAL
AVSGAIMQAVTNNPLASPDLLGINAGAAFAVVSVMAIFGAGIGDIYVWFAFLGAAIAATVVYALGSMGMVGQSPLRLVLA
GAIVATFLTSVTTVMLIFDQSTLDAVRLWTAGSVTGRNIEQVKTVAPYIIAGLIAALPFGRHLTTISLGADTSRALGQNP
IVWRGLSVAVVILLAGGAVALAGPIGFVGLVVPHVARMCIGVDYRWIIPFSALGGALLVIVADTVGRLVFGSQSFPVGVT
IALIGAPFFLYLARTRLRDGA

Specific function: Part of the ABC transporter complex yfiYZ/yfhA/yusV involved in import of the iron-hydroxamate siderophores schizokinen, arthrobactin and corprogen (Probable) [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786805, Length=307, Percent_Identity=41.042345276873, Blast_Score=181, Evalue=4e-47,
Organism=Escherichia coli, GI1790740, Length=283, Percent_Identity=34.6289752650177, Blast_Score=138, Evalue=7e-34,
Organism=Escherichia coli, GI1790741, Length=277, Percent_Identity=34.2960288808664, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1786347, Length=321, Percent_Identity=34.8909657320872, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1788004, Length=287, Percent_Identity=36.2369337979094, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1786804, Length=317, Percent_Identity=35.0157728706625, Blast_Score=114, Evalue=7e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35082; Mature: 34951

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: PS00850 GLY_RADICAL_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDRTAGYIAETDVGRVLALAALLCLLMLATVIAISLGAAMMPPAKVISALFASETSRDH
CCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCE
LIVMTIRLPRALAALLAGSALAVSGAIMQAVTNNPLASPDLLGINAGAAFAVVSVMAIFG
EEEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHC
AGIGDIYVWFAFLGAAIAATVVYALGSMGMVGQSPLRLVLAGAIVATFLTSVTTVMLIFD
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEC
QSTLDAVRLWTAGSVTGRNIEQVKTVAPYIIAGLIAALPFGRHLTTISLGADTSRALGQN
CCHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHCCCC
PIVWRGLSVAVVILLAGGAVALAGPIGFVGLVVPHVARMCIGVDYRWIIPFSALGGALLV
CCEECHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHCHHHHH
IVADTVGRLVFGSQSFPVGVTIALIGAPFFLYLARTRLRDGA
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TDRTAGYIAETDVGRVLALAALLCLLMLATVIAISLGAAMMPPAKVISALFASETSRDH
CCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCE
LIVMTIRLPRALAALLAGSALAVSGAIMQAVTNNPLASPDLLGINAGAAFAVVSVMAIFG
EEEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHC
AGIGDIYVWFAFLGAAIAATVVYALGSMGMVGQSPLRLVLAGAIVATFLTSVTTVMLIFD
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEC
QSTLDAVRLWTAGSVTGRNIEQVKTVAPYIIAGLIAALPFGRHLTTISLGADTSRALGQN
CCHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHCCCC
PIVWRGLSVAVVILLAGGAVALAGPIGFVGLVVPHVARMCIGVDYRWIIPFSALGGALLV
CCEECHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHCHHHHH
IVADTVGRLVFGSQSFPVGVTIALIGAPFFLYLARTRLRDGA
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]