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The map label for this gene is appC [H]

Identifier: 222102558

GI number: 222102558

Start: 157849

End: 158775

Strand: Reverse

Name: appC [H]

Synonym: Avi_7192

Alternate gene names: 222102558

Gene position: 158775-157849 (Counterclockwise)

Preceding gene: 222102559

Following gene: 222102557

Centisome position: 25.13

GC content: 59.12

Gene sequence:

>927_bases
ATGACCACCCAAACCCTACGTCCTTTTTCGAAACGCCACAGGTGGCGCAGGATTTCCCCCGTCACGATCTTGGCGGGTGC
CTTGGCCGTCGTGTTGGTGCTGGCTGCCTTGTTTGCCCCGCTTCTTGCGCCCCATGATCCGTTCAATCCGGCAACGCTGG
ATTTGATGGATGGCATGACACCGCCCATGGCCGCCAATGCCTTTAGTTGCAAAGTGTTTTGGCTGGGCACAGACAATCAG
GGCCGTGATATTCTCTCGTCCATTCTCTATGGCAGCCGGGTGTCCTTGCTGGTTGCCTTTTCCGCCACGCTTTTATCGCT
GGCTTTGGGTGTTGGTGCGGGGCTAATCAGCGGTTACGCAGGCAATGCCGTGGATGCCGTGATCATGCGCGTTGCCGATG
CGCAGCTGACCTTCCCGACCATTCTGGTCGCCCTGCTGATCTTTGGCATTGCCCACGGCATCATTCCGGCATCACAGCAG
GAACAGGCTGCGGTGTGGATTCTGATTTTCGCCATCGGCTTTTCCAACTGGCCCCAATTTGCCCGCACCGTGCGCGGGGC
CGTGCTGGTGGAAAAACGCAAGGATTATGTGGCGGCTGCAAAGCTCATCGGCGTCAGCCGCAGCCGCATTCTGCTCACGC
ATATCCTGCCCAATATTGCCGGGCCGGCTCTGGTGATTGCCACCATCGGTCTGGCGCTTGCTGTCATTGAAGAGGCAACC
CTGTCCTATCTTGGTGTTGGCGTGCCGCCCACGCGGCCGTCGCTTGGTACGCTGATCCGCATTGGCCAGCAATTCCTGTT
TTCGGGGGAATGGTGGATTATCGGTTTTCCCGCTGCCACGCTGGTTCTGCTGGCCCTGTCCGTCAATCTGTTGGGAGACC
GCTTGCGCGATGCGCTCAACCCGCGCCTGAGGAACAATCGCCGATGA

Upstream 100 bases:

>100_bases
ATCTCGGCTCTGTTTGTGCTCATCAATCTGATTGTTGATGGCCTCTATTACGCTGTTGATCCGCGTTTGCGGATTGTGCG
CACGGGCACGGAGTGATGCC

Downstream 100 bases:

>100_bases
GCCTGTCTTTATCCAAAACAAAACCCGTTCTGCGTATCAATAGTCTGAGCGTGGATTTTCCCGGTTTTGATGGCAATTTT
CGTGCAGTCGATGACCTATC

Product: ABC transporter membrane spanning protein (oligopeptide)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MTTQTLRPFSKRHRWRRISPVTILAGALAVVLVLAALFAPLLAPHDPFNPATLDLMDGMTPPMAANAFSCKVFWLGTDNQ
GRDILSSILYGSRVSLLVAFSATLLSLALGVGAGLISGYAGNAVDAVIMRVADAQLTFPTILVALLIFGIAHGIIPASQQ
EQAAVWILIFAIGFSNWPQFARTVRGAVLVEKRKDYVAAAKLIGVSRSRILLTHILPNIAGPALVIATIGLALAVIEEAT
LSYLGVGVPPTRPSLGTLIRIGQQFLFSGEWWIIGFPAATLVLLALSVNLLGDRLRDALNPRLRNNRR

Sequences:

>Translated_308_residues
MTTQTLRPFSKRHRWRRISPVTILAGALAVVLVLAALFAPLLAPHDPFNPATLDLMDGMTPPMAANAFSCKVFWLGTDNQ
GRDILSSILYGSRVSLLVAFSATLLSLALGVGAGLISGYAGNAVDAVIMRVADAQLTFPTILVALLIFGIAHGIIPASQQ
EQAAVWILIFAIGFSNWPQFARTVRGAVLVEKRKDYVAAAKLIGVSRSRILLTHILPNIAGPALVIATIGLALAVIEEAT
LSYLGVGVPPTRPSLGTLIRIGQQFLFSGEWWIIGFPAATLVLLALSVNLLGDRLRDALNPRLRNNRR
>Mature_307_residues
TTQTLRPFSKRHRWRRISPVTILAGALAVVLVLAALFAPLLAPHDPFNPATLDLMDGMTPPMAANAFSCKVFWLGTDNQG
RDILSSILYGSRVSLLVAFSATLLSLALGVGAGLISGYAGNAVDAVIMRVADAQLTFPTILVALLIFGIAHGIIPASQQE
QAAVWILIFAIGFSNWPQFARTVRGAVLVEKRKDYVAAAKLIGVSRSRILLTHILPNIAGPALVIATIGLALAVIEEATL
SYLGVGVPPTRPSLGTLIRIGQQFLFSGEWWIIGFPAATLVLLALSVNLLGDRLRDALNPRLRNNRR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787760, Length=284, Percent_Identity=32.7464788732394, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1789964, Length=273, Percent_Identity=39.1941391941392, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI1787054, Length=306, Percent_Identity=33.6601307189542, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1789889, Length=258, Percent_Identity=31.7829457364341, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787498, Length=317, Percent_Identity=34.7003154574132, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1788505, Length=243, Percent_Identity=32.5102880658436, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1787549, Length=298, Percent_Identity=28.1879194630872, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33013; Mature: 32881

Theoretical pI: Translated: 11.34; Mature: 11.34

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTQTLRPFSKRHRWRRISPVTILAGALAVVLVLAALFAPLLAPHDPFNPATLDLMDGMT
CCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCC
PPMAANAFSCKVFWLGTDNQGRDILSSILYGSRVSLLVAFSATLLSLALGVGAGLISGYA
CCCCCCCEEEEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GNAVDAVIMRVADAQLTFPTILVALLIFGIAHGIIPASQQEQAAVWILIFAIGFSNWPQF
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHEECCCCCCHHH
ARTVRGAVLVEKRKDYVAAAKLIGVSRSRILLTHILPNIAGPALVIATIGLALAVIEEAT
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
LSYLGVGVPPTRPSLGTLIRIGQQFLFSGEWWIIGFPAATLVLLALSVNLLGDRLRDALN
HHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCC
PRLRNNRR
CHHCCCCC
>Mature Secondary Structure 
TTQTLRPFSKRHRWRRISPVTILAGALAVVLVLAALFAPLLAPHDPFNPATLDLMDGMT
CCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCC
PPMAANAFSCKVFWLGTDNQGRDILSSILYGSRVSLLVAFSATLLSLALGVGAGLISGYA
CCCCCCCEEEEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GNAVDAVIMRVADAQLTFPTILVALLIFGIAHGIIPASQQEQAAVWILIFAIGFSNWPQF
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHEECCCCCCHHH
ARTVRGAVLVEKRKDYVAAAKLIGVSRSRILLTHILPNIAGPALVIATIGLALAVIEEAT
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
LSYLGVGVPPTRPSLGTLIRIGQQFLFSGEWWIIGFPAATLVLLALSVNLLGDRLRDALN
HHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCC
PRLRNNRR
CHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]