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The map label for this gene is dppB [C]

Identifier: 222102545

GI number: 222102545

Start: 141451

End: 142395

Strand: Reverse

Name: dppB [C]

Synonym: Avi_7174

Alternate gene names: 222102545

Gene position: 142395-141451 (Counterclockwise)

Preceding gene: 222102546

Following gene: 222102544

Centisome position: 22.54

GC content: 56.51

Gene sequence:

>945_bases
ATGACGCGATATGTTGCAAGCCGGATAGGACAGGCGGTTCTGGTGCTCTGGGCAGCCTTTACCCTGTCCTTTATTCTGTT
GCAGGCCATGCCTGGGGACGCGGTGCTGATCAAGTTTCTCAGCCCTGATTATGGGTTAAGCCCTGATCAAATCAAGGAAA
TTCGCGCCGCCTATGCCGTGGATTCCTCTGTGTTCGTCCAATATTTCCACACATTGGCGAATTTCTTACAGGGTGATTTT
GGCTATTCGCTGCACGCGGGCGTGCCGGTGACGGCGCAGTTGGCCATAGGTCTGCCTGCAACGCTCACGCTGGCAGCTCT
CGCCTTTCTTGCTGCCATCGTCCTTGCGGTCTTTGTGGCGGTGCTGTCTTCGCTCGCACCATTTTCATTTTTGCGCAATC
TGGTACAGGCAGTGCCTTCGCTGTTGATCTCGGTTCCAGTGTTCTGGCTGGGCATTATGCTGATCCAGATTTTCTCGTTT
CGGCTCAAGCTGGTCTCGGTGATCAATCCCGGACCATGGGAAAGTCTCGTCCTGCCGGTGATCACCCTGTCTGTTCCCAT
TGCCGCACCGCTGGCGCAAATCCTGATCCGCAATATTGATGAAATCCGCACCCGGCCCTTCATCTCTGTCGTCATTGCCA
AGGGGGCCACGCCCGCCCGTGTGCTGTGGCGGCATGTCGCCATCAATGCGGCTTTGCCAGTGCTGACCATTGCCGGGGTG
CTGTTTGGCGAGCTTCTGGCCGGAGCCGTGGTGACCGAAACCGTATTTGGCCTGAACGGCCTAGGCGAATTGACGGAAAA
AGCCGTCAGCACGCAGGATATTGCCGTGCTTCAGGCCATTGTGGTGATTTCCGCCACCGCCTTTGTCATCATCAATCTTC
TGGTCGATCTTGCCTATCCCCTTCTCGATCCCCGCCTGAGAAGCCGGAACGGAGCCGCATCATGA

Upstream 100 bases:

>100_bases
CCCGCCCCAGCTTCTACAGCGTCTGGCTGGATAAGTAATGGTCAGCACCCGGGTGACAGCAACAGCCGCCACCCGGTTTT
GAAATCTGCGGAGATCGATG

Downstream 100 bases:

>100_bases
GCAGTGTTGAAATTCTCTCCCTGCAAGCCAATGGCGTGAAATCGGATAGCGTCAAGCGCCGGGCGTCCCTCACCCGTTTT
AAAGGCTTGCGCCCCGGTCT

Product: ABC transporter membrane spanning protein (dipeptide)

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MTRYVASRIGQAVLVLWAAFTLSFILLQAMPGDAVLIKFLSPDYGLSPDQIKEIRAAYAVDSSVFVQYFHTLANFLQGDF
GYSLHAGVPVTAQLAIGLPATLTLAALAFLAAIVLAVFVAVLSSLAPFSFLRNLVQAVPSLLISVPVFWLGIMLIQIFSF
RLKLVSVINPGPWESLVLPVITLSVPIAAPLAQILIRNIDEIRTRPFISVVIAKGATPARVLWRHVAINAALPVLTIAGV
LFGELLAGAVVTETVFGLNGLGELTEKAVSTQDIAVLQAIVVISATAFVIINLLVDLAYPLLDPRLRSRNGAAS

Sequences:

>Translated_314_residues
MTRYVASRIGQAVLVLWAAFTLSFILLQAMPGDAVLIKFLSPDYGLSPDQIKEIRAAYAVDSSVFVQYFHTLANFLQGDF
GYSLHAGVPVTAQLAIGLPATLTLAALAFLAAIVLAVFVAVLSSLAPFSFLRNLVQAVPSLLISVPVFWLGIMLIQIFSF
RLKLVSVINPGPWESLVLPVITLSVPIAAPLAQILIRNIDEIRTRPFISVVIAKGATPARVLWRHVAINAALPVLTIAGV
LFGELLAGAVVTETVFGLNGLGELTEKAVSTQDIAVLQAIVVISATAFVIINLLVDLAYPLLDPRLRSRNGAAS
>Mature_313_residues
TRYVASRIGQAVLVLWAAFTLSFILLQAMPGDAVLIKFLSPDYGLSPDQIKEIRAAYAVDSSVFVQYFHTLANFLQGDFG
YSLHAGVPVTAQLAIGLPATLTLAALAFLAAIVLAVFVAVLSSLAPFSFLRNLVQAVPSLLISVPVFWLGIMLIQIFSFR
LKLVSVINPGPWESLVLPVITLSVPIAAPLAQILIRNIDEIRTRPFISVVIAKGATPARVLWRHVAINAALPVLTIAGVL
FGELLAGAVVTETVFGLNGLGELTEKAVSTQDIAVLQAIVVISATAFVIINLLVDLAYPLLDPRLRSRNGAAS

Specific function: Probably part of the binding-protein-dependent transport system y4tOPQRS for a peptide. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=341, Percent_Identity=28.7390029325513, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI1787053, Length=310, Percent_Identity=29.6774193548387, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI1789888, Length=314, Percent_Identity=28.0254777070064, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1787497, Length=310, Percent_Identity=27.0967741935484, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1787550, Length=273, Percent_Identity=27.8388278388278, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1788504, Length=285, Percent_Identity=28.4210526315789, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1787761, Length=334, Percent_Identity=28.1437125748503, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33517; Mature: 33386

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: PS00101 HEXAPEP_TRANSFERASES ; PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRYVASRIGQAVLVLWAAFTLSFILLQAMPGDAVLIKFLSPDYGLSPDQIKEIRAAYAV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHH
DSSVFVQYFHTLANFLQGDFGYSLHAGVPVTAQLAIGLPATLTLAALAFLAAIVLAVFVA
HHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VLSSLAPFSFLRNLVQAVPSLLISVPVFWLGIMLIQIFSFRLKLVSVINPGPWESLVLPV
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
ITLSVPIAAPLAQILIRNIDEIRTRPFISVVIAKGATPARVLWRHVAINAALPVLTIAGV
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHH
LFGELLAGAVVTETVFGLNGLGELTEKAVSTQDIAVLQAIVVISATAFVIINLLVDLAYP
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLDPRLRSRNGAAS
HHCCHHHCCCCCCC
>Mature Secondary Structure 
TRYVASRIGQAVLVLWAAFTLSFILLQAMPGDAVLIKFLSPDYGLSPDQIKEIRAAYAV
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHH
DSSVFVQYFHTLANFLQGDFGYSLHAGVPVTAQLAIGLPATLTLAALAFLAAIVLAVFVA
HHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VLSSLAPFSFLRNLVQAVPSLLISVPVFWLGIMLIQIFSFRLKLVSVINPGPWESLVLPV
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
ITLSVPIAAPLAQILIRNIDEIRTRPFISVVIAKGATPARVLWRHVAINAALPVLTIAGV
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHH
LFGELLAGAVVTETVFGLNGLGELTEKAVSTQDIAVLQAIVVISATAFVIINLLVDLAYP
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLDPRLRSRNGAAS
HHCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9163424; 8796346 [H]