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The map label for this gene is potC [H]

Identifier: 222102511

GI number: 222102511

Start: 106364

End: 107209

Strand: Direct

Name: potC [H]

Synonym: Avi_7131

Alternate gene names: 222102511

Gene position: 106364-107209 (Clockwise)

Preceding gene: 222102510

Following gene: 222102512

Centisome position: 16.84

GC content: 56.97

Gene sequence:

>846_bases
ATGCGCGAGCGTGGACAACCAAGACCTGCTTCCTTCTATCTGCTGTTGGGCATTTTCGCTGTCTATCTGGCCTTTCTCTA
TGGGCCGATGCTGTGTGTGTTCATCCTGTCCTTTCAGGGACCAAGCGGCGGCATGAGCTTTCCCATGGTCGGGGTTTCAA
CCCATTGGTTTCAGGTGCTGCTGGGCGGCACGGGCGGCGAAGGGGTTGGCGATCTGCATGATGCCTTCTTTCGTTCCATG
CGCCTCGCCGCTATTGTAGCGGTGCTGACCATGACGATATCGGTGGCGGCAGGCATGGCCTATCGGCGAAAGTTCCCTGG
GGCCAATCTGGTATTTTACTCTGCAATAGCGGCCATGGTGCTGCCGGGGATTTTTGTTGGTTTTGGCATCGCGCTGGCCT
TCCATCTGCTGGGCTACAAGATCCAGTGGTATTCGTCGGGTATTGGCGCGCAGCTCACCTGGTCACTGCCTTTTGGCCTG
TTAATCATGTTTATCGTGATGGGGCGTTTCAACCGGTCCTATGAAGAGGCCGCCACGGATCTTGGTGCCACCAGCTGGCA
GCGCTTCAGCCAGGTAATCTTGCCAATCATTCTGCCAGGCGTCGTTGGGATCTTCATGGCCGGTTTTACCTCCTCCTATG
AAGAATTGGCCCGCACGTCACTCAATGTCGGCTCGGGCAATACCATGCCGATGGAAATCACCGGATTGCTGACGGCGGCC
ACATCACCGGTGCTGTTTGCCATTGGCACGCTGACGACCGCGGTGTCCTTCATTCTCGTCATCGGCATGCTGCTTCTGGC
GACGACGCTGGCCAAGCGGCAACAGTCGAGATTGCAACCGCATTGA

Upstream 100 bases:

>100_bases
GGCAAAATCGGTTGTGATGCTGGTCATTGTGCTGGGCTTCGTCGCCTCTCTGCTGCGCCTCGTTGATATCCGAAAAGAAC
TGGCCAATCAGGAGTGAATG

Downstream 100 bases:

>100_bases
TGCGACCCATTCCATGAGGATGTAATAATGAGACATGAAACACAGCTGACAACAGTTCCGACGGATAGCGTTGCGAAGAA
TGTGATCCAGAAAACCGCCC

Product: ABC transporter membrane spanning protein (spermidine/putrescine)

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MRERGQPRPASFYLLLGIFAVYLAFLYGPMLCVFILSFQGPSGGMSFPMVGVSTHWFQVLLGGTGGEGVGDLHDAFFRSM
RLAAIVAVLTMTISVAAGMAYRRKFPGANLVFYSAIAAMVLPGIFVGFGIALAFHLLGYKIQWYSSGIGAQLTWSLPFGL
LIMFIVMGRFNRSYEEAATDLGATSWQRFSQVILPIILPGVVGIFMAGFTSSYEELARTSLNVGSGNTMPMEITGLLTAA
TSPVLFAIGTLTTAVSFILVIGMLLLATTLAKRQQSRLQPH

Sequences:

>Translated_281_residues
MRERGQPRPASFYLLLGIFAVYLAFLYGPMLCVFILSFQGPSGGMSFPMVGVSTHWFQVLLGGTGGEGVGDLHDAFFRSM
RLAAIVAVLTMTISVAAGMAYRRKFPGANLVFYSAIAAMVLPGIFVGFGIALAFHLLGYKIQWYSSGIGAQLTWSLPFGL
LIMFIVMGRFNRSYEEAATDLGATSWQRFSQVILPIILPGVVGIFMAGFTSSYEELARTSLNVGSGNTMPMEITGLLTAA
TSPVLFAIGTLTTAVSFILVIGMLLLATTLAKRQQSRLQPH
>Mature_281_residues
MRERGQPRPASFYLLLGIFAVYLAFLYGPMLCVFILSFQGPSGGMSFPMVGVSTHWFQVLLGGTGGEGVGDLHDAFFRSM
RLAAIVAVLTMTISVAAGMAYRRKFPGANLVFYSAIAAMVLPGIFVGFGIALAFHLLGYKIQWYSSGIGAQLTWSLPFGL
LIMFIVMGRFNRSYEEAATDLGATSWQRFSQVILPIILPGVVGIFMAGFTSSYEELARTSLNVGSGNTMPMEITGLLTAA
TSPVLFAIGTLTTAVSFILVIGMLLLATTLAKRQQSRLQPH

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=242, Percent_Identity=25.2066115702479, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1787714, Length=211, Percent_Identity=27.4881516587678, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787081, Length=262, Percent_Identity=28.6259541984733, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30293; Mature: 30293

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRERGQPRPASFYLLLGIFAVYLAFLYGPMLCVFILSFQGPSGGMSFPMVGVSTHWFQVL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
LGGTGGEGVGDLHDAFFRSMRLAAIVAVLTMTISVAAGMAYRRKFPGANLVFYSAIAAMV
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
LPGIFVGFGIALAFHLLGYKIQWYSSGIGAQLTWSLPFGLLIMFIVMGRFNRSYEEAATD
HHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEECCHHHHHHHHHHHHHCCCCHHHHHHH
LGATSWQRFSQVILPIILPGVVGIFMAGFTSSYEELARTSLNVGSGNTMPMEITGLLTAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
TSPVLFAIGTLTTAVSFILVIGMLLLATTLAKRQQSRLQPH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRERGQPRPASFYLLLGIFAVYLAFLYGPMLCVFILSFQGPSGGMSFPMVGVSTHWFQVL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
LGGTGGEGVGDLHDAFFRSMRLAAIVAVLTMTISVAAGMAYRRKFPGANLVFYSAIAAMV
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
LPGIFVGFGIALAFHLLGYKIQWYSSGIGAQLTWSLPFGLLIMFIVMGRFNRSYEEAATD
HHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEECCHHHHHHHHHHHHHCCCCHHHHHHH
LGATSWQRFSQVILPIILPGVVGIFMAGFTSSYEELARTSLNVGSGNTMPMEITGLLTAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
TSPVLFAIGTLTTAVSFILVIGMLLLATTLAKRQQSRLQPH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]