Click here to switch to the map view.

The map label for this gene is tkt [H]

Identifier: 222096847

GI number: 222096847

Start: 3138274

End: 3140268

Strand: Reverse

Name: tkt [H]

Synonym: BCQ_3187

Alternate gene names: 222096847

Gene position: 3140268-3138274 (Counterclockwise)

Preceding gene: 222096848

Following gene: 222096846

Centisome position: 60.23

GC content: 39.8

Gene sequence:

>1995_bases
ATGACACAAAACATAAATCAATTAGCAGTGAATACAATTCGTACGTTATCAATTGATGCTATTAATGCGGCAAATTCAGG
TCATCCAGGTCTTCCGATGGGAGCAGCGCCAATGGCTTATGCATTATGGGCGAATCATTTAAATCATAATCCTAATCATC
CAAAATGGTTTAACCGTGATCGCTTCGTTTTATCGGCGGGACATGGATCTAGCTTATTATATAGCCTACTTCATTTAGCT
GGATATGACGTTTCAATTGATGACTTGAAAAACTTCAGAAAGTTAAATAGTAAAACACCAGGTCATCCTGAGTTTGGTCA
CACTTCTGGAGTTGAAGCGACGACAGGACCGTTAGGACAAGGGATTGCCAATGCTGTCGGAATGGCAATGGCAGAAGCGC
ATTTAGCGGCGAAGTTCAATAAGGGTGGTCACTCTATTATTGATCACAATACGTACGCTTTAGTTGGAGACGGTGATTTA
ATGGAAGGTGTCGCTTATGAAGCGATGTCAATGGCAGGACATATGAAACTTGGCAAGTTAATTGTGCTGTATGATTCAAA
TGAAATTTCACTTGATGGTGAATTAAACATTGCTTTCTCTGAAGATATGCAGAAAAGAGTAGAATCTGCACATTGGCAAT
ATGTAAGAGTTGAAGATGGAAACGATGTTGATGCGATTACAAAAGCGATTCAATTAGCGAAAGATAATACGGACCAACCT
ACTCTTATAGAAATTAGAACCATTATAGGTTACGGAAGTCCAAAAGTTGCTGGAACGAACAAAGCACATGGTAATCCGCT
TGGAGTAGAAGAAGCGACAGCGACAAAACAAGTGTATGGTTGGCATTATGAAGAAGACTTCTTTGTACCTGAAGAAGTAA
CAGCTCATTTTAATGAACTGAAACAAAAAGGTATTGAAAAAGAAAATGGCTGGAATGAGCAGTTCAACTTATACAGAGAG
TCAAACCCTGCACTAGCAGATGAATTAGAAAAAGCGATTACAGGTGAAGTTTTAATCGAAGCGAAAGACATTTTATCCTT
CGATACTGAAAAAACGATTTCAACTCGTGTTGCAAGTGGGGGAGCTATTAATCATTATGTGAAATCGATTCCTTCTATTT
TCGGTGGAAGTGCGGATCTTTCTCATTCTACGATGACAGATATAAAAGGTGAAGCAGTGTATGCAGTAGAATCGTATGCT
GGCCGAAATATATACTTCGGTGTACGTGAACATGCAATGGGCGCGGCAGCGAATGGACTGGCTCTTCATGGAGGAGTAAA
ACCGTTCGTGAGTACATTCTTTGTATTTAATGACTATCTTCGTCCATCTATTCGACTGGCTGCATTGCAAAAGTTACCTG
TTACGTACGTATTTACACATGATTCGATTGCTGTAGGAGAAGATGGTCCAACGCATGAACCTATTGAACATTTAGCAGCT
CTTCGGGCAATTCCTGGTTTAACAGTTATCCGTCCGTCAGATGCAAATGAAACAGCAAGTGCGTGGGCATATGCTTTACA
GCAAACGGAAGGTCCGGTCGTTTTAGTACTGAGCCGTCAAAATTTACCGGTATTTAATGAAACGAAAGCGAACATAGAGA
ATCTTTCTAAAGGAGCTTACGTATTAACACAAACGAATGAAAATCCAGATGTGATTTTAATTGCGACAGGTTCTGAAGTT
TCTTTAGCTGCTAGTGCGAAAGCGAAATTAGAAGAAGATCAAGTTTCTGTTCGTATCGTTGCAATGCCAAGCTGGGAGTT
ATTCGATCGTCAATCGAACGAATATAAAGAATCCGTTCTTCCGTCTTCTGTAACGAAACGAGTATCTCTTGAGATGGGTG
TATCTCTCGGGTGGGAGCGTTATGTAGGACAAGAAGGAAAAGTACTATCAATTGAAACATTTGGAGCTTCAGGCACTGGA
GCTGAAGTCATGAATCTATTTGGATTTACGACAGAAAATGTTGTTCAAATTACAAAAAATGTGTTGAATTCTTAA

Upstream 100 bases:

>100_bases
TAATGAATTATTGCAAGAAAGTGGATTTAAATGGTGGTTAGATCAAGAAACGAAAAAATAAGTACTTTCTTTCATGAAAG
CATGTAGGGGGACGATTACT

Downstream 100 bases:

>100_bases
GCTATGACTGTGAATACCTTTCTGTACATACTAACATTTCAGTGCTGAAAGGTATTCCAGATTGTAGTGATATGAATTTT
TAATAAAAGATAATTTGAGG

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 664; Mature: 663

Protein sequence:

>664_residues
MTQNINQLAVNTIRTLSIDAINAANSGHPGLPMGAAPMAYALWANHLNHNPNHPKWFNRDRFVLSAGHGSSLLYSLLHLA
GYDVSIDDLKNFRKLNSKTPGHPEFGHTSGVEATTGPLGQGIANAVGMAMAEAHLAAKFNKGGHSIIDHNTYALVGDGDL
MEGVAYEAMSMAGHMKLGKLIVLYDSNEISLDGELNIAFSEDMQKRVESAHWQYVRVEDGNDVDAITKAIQLAKDNTDQP
TLIEIRTIIGYGSPKVAGTNKAHGNPLGVEEATATKQVYGWHYEEDFFVPEEVTAHFNELKQKGIEKENGWNEQFNLYRE
SNPALADELEKAITGEVLIEAKDILSFDTEKTISTRVASGGAINHYVKSIPSIFGGSADLSHSTMTDIKGEAVYAVESYA
GRNIYFGVREHAMGAAANGLALHGGVKPFVSTFFVFNDYLRPSIRLAALQKLPVTYVFTHDSIAVGEDGPTHEPIEHLAA
LRAIPGLTVIRPSDANETASAWAYALQQTEGPVVLVLSRQNLPVFNETKANIENLSKGAYVLTQTNENPDVILIATGSEV
SLAASAKAKLEEDQVSVRIVAMPSWELFDRQSNEYKESVLPSSVTKRVSLEMGVSLGWERYVGQEGKVLSIETFGASGTG
AEVMNLFGFTTENVVQITKNVLNS

Sequences:

>Translated_664_residues
MTQNINQLAVNTIRTLSIDAINAANSGHPGLPMGAAPMAYALWANHLNHNPNHPKWFNRDRFVLSAGHGSSLLYSLLHLA
GYDVSIDDLKNFRKLNSKTPGHPEFGHTSGVEATTGPLGQGIANAVGMAMAEAHLAAKFNKGGHSIIDHNTYALVGDGDL
MEGVAYEAMSMAGHMKLGKLIVLYDSNEISLDGELNIAFSEDMQKRVESAHWQYVRVEDGNDVDAITKAIQLAKDNTDQP
TLIEIRTIIGYGSPKVAGTNKAHGNPLGVEEATATKQVYGWHYEEDFFVPEEVTAHFNELKQKGIEKENGWNEQFNLYRE
SNPALADELEKAITGEVLIEAKDILSFDTEKTISTRVASGGAINHYVKSIPSIFGGSADLSHSTMTDIKGEAVYAVESYA
GRNIYFGVREHAMGAAANGLALHGGVKPFVSTFFVFNDYLRPSIRLAALQKLPVTYVFTHDSIAVGEDGPTHEPIEHLAA
LRAIPGLTVIRPSDANETASAWAYALQQTEGPVVLVLSRQNLPVFNETKANIENLSKGAYVLTQTNENPDVILIATGSEV
SLAASAKAKLEEDQVSVRIVAMPSWELFDRQSNEYKESVLPSSVTKRVSLEMGVSLGWERYVGQEGKVLSIETFGASGTG
AEVMNLFGFTTENVVQITKNVLNS
>Mature_663_residues
TQNINQLAVNTIRTLSIDAINAANSGHPGLPMGAAPMAYALWANHLNHNPNHPKWFNRDRFVLSAGHGSSLLYSLLHLAG
YDVSIDDLKNFRKLNSKTPGHPEFGHTSGVEATTGPLGQGIANAVGMAMAEAHLAAKFNKGGHSIIDHNTYALVGDGDLM
EGVAYEAMSMAGHMKLGKLIVLYDSNEISLDGELNIAFSEDMQKRVESAHWQYVRVEDGNDVDAITKAIQLAKDNTDQPT
LIEIRTIIGYGSPKVAGTNKAHGNPLGVEEATATKQVYGWHYEEDFFVPEEVTAHFNELKQKGIEKENGWNEQFNLYRES
NPALADELEKAITGEVLIEAKDILSFDTEKTISTRVASGGAINHYVKSIPSIFGGSADLSHSTMTDIKGEAVYAVESYAG
RNIYFGVREHAMGAAANGLALHGGVKPFVSTFFVFNDYLRPSIRLAALQKLPVTYVFTHDSIAVGEDGPTHEPIEHLAAL
RAIPGLTVIRPSDANETASAWAYALQQTEGPVVLVLSRQNLPVFNETKANIENLSKGAYVLTQTNENPDVILIATGSEVS
LAASAKAKLEEDQVSVRIVAMPSWELFDRQSNEYKESVLPSSVTKRVSLEMGVSLGWERYVGQEGKVLSIETFGASGTGA
EVMNLFGFTTENVVQITKNVLNS

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=671, Percent_Identity=26.6766020864382, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI4507521, Length=671, Percent_Identity=26.6766020864382, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI133778974, Length=662, Percent_Identity=25.8308157099698, Blast_Score=162, Evalue=1e-39,
Organism=Homo sapiens, GI225637459, Length=680, Percent_Identity=21.9117647058824, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI225637463, Length=596, Percent_Identity=22.3154362416107, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI225637461, Length=596, Percent_Identity=22.3154362416107, Blast_Score=124, Evalue=3e-28,
Organism=Escherichia coli, GI48994911, Length=658, Percent_Identity=48.0243161094225, Blast_Score=636, Evalue=0.0,
Organism=Escherichia coli, GI1788808, Length=666, Percent_Identity=47.1471471471471, Blast_Score=622, Evalue=1e-179,
Organism=Caenorhabditis elegans, GI17539652, Length=660, Percent_Identity=25.7575757575758, Blast_Score=170, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6325331, Length=674, Percent_Identity=46.2908011869436, Blast_Score=584, Evalue=1e-167,
Organism=Saccharomyces cerevisiae, GI6319593, Length=672, Percent_Identity=44.1964285714286, Blast_Score=551, Evalue=1e-157,
Organism=Drosophila melanogaster, GI45551847, Length=679, Percent_Identity=27.3932253313697, Blast_Score=206, Evalue=4e-53,
Organism=Drosophila melanogaster, GI45550715, Length=679, Percent_Identity=27.3932253313697, Blast_Score=206, Evalue=4e-53,
Organism=Drosophila melanogaster, GI24645119, Length=640, Percent_Identity=27.03125, Blast_Score=189, Evalue=4e-48,
Organism=Drosophila melanogaster, GI24666278, Length=582, Percent_Identity=27.8350515463918, Blast_Score=186, Evalue=4e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 72055; Mature: 71924

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQNINQLAVNTIRTLSIDAINAANSGHPGLPMGAAPMAYALWANHLNHNPNHPKWFNRD
CCCCHHHHHHHHHHEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
RFVLSAGHGSSLLYSLLHLAGYDVSIDDLKNFRKLNSKTPGHPEFGHTSGVEATTGPLGQ
EEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHH
GIANAVGMAMAEAHLAAKFNKGGHSIIDHNTYALVGDGDLMEGVAYEAMSMAGHMKLGKL
HHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEEECCHHHHHHHHHHHHHHCCEEECCE
IVLYDSNEISLDGELNIAFSEDMQKRVESAHWQYVRVEDGNDVDAITKAIQLAKDNTDQP
EEEECCCEEEECCEEEEEEHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHCCCCCCC
TLIEIRTIIGYGSPKVAGTNKAHGNPLGVEEATATKQVYGWHYEEDFFVPEEVTAHFNEL
EEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHCCEECCCCCCCHHHHHHHHHHH
KQKGIEKENGWNEQFNLYRESNPALADELEKAITGEVLIEAKDILSFDTEKTISTRVASG
HHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCEEEEEHHHHCCCCCHHHHHHHCCC
GAINHYVKSIPSIFGGSADLSHSTMTDIKGEAVYAVESYAGRNIYFGVREHAMGAAANGL
CHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCEEEEEECCCCCEEEEEEHHHHCCCCCCCE
ALHGGVKPFVSTFFVFNDYLRPSIRLAALQKLPVTYVFTHDSIAVGEDGPTHEPIEHLAA
EEECCHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEEECCCEEECCCCCCHHHHHHHHH
LRAIPGLTVIRPSDANETASAWAYALQQTEGPVVLVLSRQNLPVFNETKANIENLSKGAY
HHHCCCCEEECCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHCCCCEE
VLTQTNENPDVILIATGSEVSLAASAKAKLEEDQVSVRIVAMPSWELFDRQSNEYKESVL
EEEECCCCCCEEEEECCCCEEEEECCHHHCCCCCEEEEEEEECCHHHHCCCCHHHHHHCC
PSSVTKRVSLEMGVSLGWERYVGQEGKVLSIETFGASGTGAEVMNLFGFTTENVVQITKN
CHHHHHHEEEECCCCCCHHHHCCCCCCEEEEEECCCCCCCHHHHHHHCCCHHHHHHHHHH
VLNS
HHCC
>Mature Secondary Structure 
TQNINQLAVNTIRTLSIDAINAANSGHPGLPMGAAPMAYALWANHLNHNPNHPKWFNRD
CCCHHHHHHHHHHEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
RFVLSAGHGSSLLYSLLHLAGYDVSIDDLKNFRKLNSKTPGHPEFGHTSGVEATTGPLGQ
EEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHH
GIANAVGMAMAEAHLAAKFNKGGHSIIDHNTYALVGDGDLMEGVAYEAMSMAGHMKLGKL
HHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEEECCHHHHHHHHHHHHHHCCEEECCE
IVLYDSNEISLDGELNIAFSEDMQKRVESAHWQYVRVEDGNDVDAITKAIQLAKDNTDQP
EEEECCCEEEECCEEEEEEHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHCCCCCCC
TLIEIRTIIGYGSPKVAGTNKAHGNPLGVEEATATKQVYGWHYEEDFFVPEEVTAHFNEL
EEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHCCEECCCCCCCHHHHHHHHHHH
KQKGIEKENGWNEQFNLYRESNPALADELEKAITGEVLIEAKDILSFDTEKTISTRVASG
HHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCEEEEEHHHHCCCCCHHHHHHHCCC
GAINHYVKSIPSIFGGSADLSHSTMTDIKGEAVYAVESYAGRNIYFGVREHAMGAAANGL
CHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCEEEEEECCCCCEEEEEEHHHHCCCCCCCE
ALHGGVKPFVSTFFVFNDYLRPSIRLAALQKLPVTYVFTHDSIAVGEDGPTHEPIEHLAA
EEECCHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEEECCCEEECCCCCCHHHHHHHHH
LRAIPGLTVIRPSDANETASAWAYALQQTEGPVVLVLSRQNLPVFNETKANIENLSKGAY
HHHCCCCEEECCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHCCCCEE
VLTQTNENPDVILIATGSEVSLAASAKAKLEEDQVSVRIVAMPSWELFDRQSNEYKESVL
EEEECCCCCCEEEEECCCCEEEEECCHHHCCCCCEEEEEEEECCHHHHCCCCHHHHHHCC
PSSVTKRVSLEMGVSLGWERYVGQEGKVLSIETFGASGTGAEVMNLFGFTTENVVQITKN
CHHHHHHEEEECCCCCCHHHHCCCCCCEEEEEECCCCCCCHHHHHHHCCCHHHHHHHHHH
VLNS
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]