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The map label for this gene is yyaH [H]

Identifier: 222096811

GI number: 222096811

Start: 3102660

End: 3103040

Strand: Reverse

Name: yyaH [H]

Synonym: BCQ_3151

Alternate gene names: 222096811

Gene position: 3103040-3102660 (Counterclockwise)

Preceding gene: 222096812

Following gene: 222096808

Centisome position: 59.51

GC content: 35.96

Gene sequence:

>381_bases
ATGAAAATTGAACATGTAGCAATTTGGGTGAATGATTTAGAAGGAATGCGTGATTTTTATAAAAAGTACTTTAATGGTGA
AGAAAATAGCTTATATCACAATCCGAAAAAGCAGTTTGAATCTTATTTCATAACTTTTGAAGGTGGTGCGCGTCTAGAAC
TTATGAAGCGGGTAGGGATAGAGGATGCATTACAAACAGAAACAATAGGATATGCGCATATTGCTTTTTCTGTAGGTAGT
AAAGAAAAAGTGAACGAATTAACGAATACATTAAGAGAAGCAGGATACGCTGTGTTAAACGGCCCACGAACTACAGGGGA
TGGTTACTACGAAAGTGTAGTAAGTGATCCTGAAGGAAATCAGATTGAGATAACGATCTAA

Upstream 100 bases:

>100_bases
CTTGATCTTATGATTACGAGAACGAATAAAGAAAATTAAATGTGCTGGCAATGAAGCATCCAATTTTCAGTTGAATAACA
TAAAAGAAAAGGTGCCAATT

Downstream 100 bases:

>100_bases
CATGAACAACCTCATTTCGCATTATCATGACGGGAGATGAGGCTGTTTTATTTTTATCTTTAATTGGAGTGATGAAAATG
GCGAAGAATCCCCTCAATAA

Product: glyoxylase family protein (lactoylglutathione lyase)

Products: glutathione; methylglyoxal

Alternate protein names: ORFF [H]

Number of amino acids: Translated: 126; Mature: 126

Protein sequence:

>126_residues
MKIEHVAIWVNDLEGMRDFYKKYFNGEENSLYHNPKKQFESYFITFEGGARLELMKRVGIEDALQTETIGYAHIAFSVGS
KEKVNELTNTLREAGYAVLNGPRTTGDGYYESVVSDPEGNQIEITI

Sequences:

>Translated_126_residues
MKIEHVAIWVNDLEGMRDFYKKYFNGEENSLYHNPKKQFESYFITFEGGARLELMKRVGIEDALQTETIGYAHIAFSVGS
KEKVNELTNTLREAGYAVLNGPRTTGDGYYESVVSDPEGNQIEITI
>Mature_126_residues
MKIEHVAIWVNDLEGMRDFYKKYFNGEENSLYHNPKKQFESYFITFEGGARLELMKRVGIEDALQTETIGYAHIAFSVGS
KEKVNELTNTLREAGYAVLNGPRTTGDGYYESVVSDPEGNQIEITI

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: 4.4.1.5

Molecular weight: Translated: 14335; Mature: 14335

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIEHVAIWVNDLEGMRDFYKKYFNGEENSLYHNPKKQFESYFITFEGGARLELMKRVGI
CCCEEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCEEEEEECCCCHHHHHHHCCC
EDALQTETIGYAHIAFSVGSKEKVNELTNTLREAGYAVLNGPRTTGDGYYESVVSDPEGN
HHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHHCCCCCCC
QIEITI
EEEEEC
>Mature Secondary Structure
MKIEHVAIWVNDLEGMRDFYKKYFNGEENSLYHNPKKQFESYFITFEGGARLELMKRVGI
CCCEEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCEEEEEECCCCHHHHHHHCCC
EDALQTETIGYAHIAFSVGSKEKVNELTNTLREAGYAVLNGPRTTGDGYYESVVSDPEGN
HHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHHCCCCCCC
QIEITI
EEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-S-lactoylglutathione

Specific reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 8011666; 9384377 [H]