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The map label for this gene is matE [H]

Identifier: 222096622

GI number: 222096622

Start: 2898397

End: 2899725

Strand: Reverse

Name: matE [H]

Synonym: BCQ_2962

Alternate gene names: 222096622

Gene position: 2899725-2898397 (Counterclockwise)

Preceding gene: 222096623

Following gene: 222096620

Centisome position: 55.61

GC content: 34.84

Gene sequence:

>1329_bases
ATGTCTATTTTTCTAGTTCCCTTGCTTTTAAGTAACATATTACAATCAGTTGGACAATTATTTGGTATGGTGGTAGTAGG
ACGATGGCTTGGTGTGAATGAATTAGCTGCCATTTCAGCATTTTTCCCATTATTCTTTTTACTTGTTTCGTTTGTAATTG
GAATTGGATCAGGTAGTTCGATTTTAATTGGTCAGGCATTTGGAGCCCGTAATGAAGATCGTTTAAAAGCCATTGTTGGT
ACGACGTTGACATTTACCTTTATAATAGGAGTTATTTTGGCAATAGTGGGAAATGTATTTGCTCTGAACATTATGCGTTT
TATGGGTACGCCAGAGAATATAATTGATATGAGTGTGCATTATGCGCGTATTTTATTTATTTCTATGCCAGTTTTATTTC
TATATTTCTCTTATACAACGTTTATAAGAGGTACAGGAGATTCTAAGACACCGTTTTATTTCTTAATTGTTAGTACAGTC
TTAAATATAATTCTATTACCTATTCTAATTTTTGGTTGGCTAGGAATACCCAAACTTGGTGTGTACGGAGCTGCCTATGC
TTCTGTTATCTCGACAGTTGTAACATTTATTGTTATGCTTATTTATTTAAAAAAGAAGAATCATCCACTGCAATTAGATG
AGACCGTACGGAAATATCTTCGTATGGATTGGGATTTATTAAAACTATTATTACGCCTTGGAATTCCAGCGAGTATTAAT
ATGATTCTTGTTTCGTTATCTGAGATTGCGGTAATCGCATTTGTGAATCGTTTCGGTTCTGATGCGACTGCTGCATATGG
GGTTGTAAACCAGGTTGCAAGTTATGTTCAGATGCCTGCGGTTAGCCTTGGAATTACGGTATCTATTTTCGCTGCGCAAT
CTATTGGTGGGAAACAATTTAACCGATTACAGGAAGTTATTCGTGCTGGAATTATTATGAATTATATAATTGGTGGTATA
CTAATCGCTTTTATTTACTTGTTTTCAAGAGAAATCTTATCGTTATTCTTAACGAACACGAATACAGTTGAAATTGCGCA
TAGTTTGGTGATGATTACACTTTGGAGTTACTTAATTTTCGGTCATGCTCAAATTATTGGTGCAACAATGCGAGCAAGTG
GAACTGTATTATGGCCCACTATTATCGGTGTCGTATCAATATGGCTTGTAGAAGTCCCTGTTGCTTATTACCTTTCTTAT
CATACAAATCTTGGTATAAAAGGAATATGGATTGGGTATCCAGCAGCATTTATTGTAAGTTTACTTTTGCAATATGGATA
TTATAAACTTTCATGGAAGAAGAAACGAATTTCACGACTTGTTAGTTAG

Upstream 100 bases:

>100_bases
ATAAAAGGGGAAATCAAATGTGAAATCATCGATAGATAGTATTCAAGAAAGTAAAAAATTAAAAAATCAACAAAAGGGAG
AGAAAACAACATGGAAATTA

Downstream 100 bases:

>100_bases
AATAGAAGGTGAAAAATGATATTCTCTTATAAGTTGTCAGTTTTAGGAGTAGGACCATAACATCATCAAACGAATAAAAC
CGAGTTACCCTCAAACGGCA

Product: Na+ driven multidrug efflux pump

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MSIFLVPLLLSNILQSVGQLFGMVVVGRWLGVNELAAISAFFPLFFLLVSFVIGIGSGSSILIGQAFGARNEDRLKAIVG
TTLTFTFIIGVILAIVGNVFALNIMRFMGTPENIIDMSVHYARILFISMPVLFLYFSYTTFIRGTGDSKTPFYFLIVSTV
LNIILLPILIFGWLGIPKLGVYGAAYASVISTVVTFIVMLIYLKKKNHPLQLDETVRKYLRMDWDLLKLLLRLGIPASIN
MILVSLSEIAVIAFVNRFGSDATAAYGVVNQVASYVQMPAVSLGITVSIFAAQSIGGKQFNRLQEVIRAGIIMNYIIGGI
LIAFIYLFSREILSLFLTNTNTVEIAHSLVMITLWSYLIFGHAQIIGATMRASGTVLWPTIIGVVSIWLVEVPVAYYLSY
HTNLGIKGIWIGYPAAFIVSLLLQYGYYKLSWKKKRISRLVS

Sequences:

>Translated_442_residues
MSIFLVPLLLSNILQSVGQLFGMVVVGRWLGVNELAAISAFFPLFFLLVSFVIGIGSGSSILIGQAFGARNEDRLKAIVG
TTLTFTFIIGVILAIVGNVFALNIMRFMGTPENIIDMSVHYARILFISMPVLFLYFSYTTFIRGTGDSKTPFYFLIVSTV
LNIILLPILIFGWLGIPKLGVYGAAYASVISTVVTFIVMLIYLKKKNHPLQLDETVRKYLRMDWDLLKLLLRLGIPASIN
MILVSLSEIAVIAFVNRFGSDATAAYGVVNQVASYVQMPAVSLGITVSIFAAQSIGGKQFNRLQEVIRAGIIMNYIIGGI
LIAFIYLFSREILSLFLTNTNTVEIAHSLVMITLWSYLIFGHAQIIGATMRASGTVLWPTIIGVVSIWLVEVPVAYYLSY
HTNLGIKGIWIGYPAAFIVSLLLQYGYYKLSWKKKRISRLVS
>Mature_441_residues
SIFLVPLLLSNILQSVGQLFGMVVVGRWLGVNELAAISAFFPLFFLLVSFVIGIGSGSSILIGQAFGARNEDRLKAIVGT
TLTFTFIIGVILAIVGNVFALNIMRFMGTPENIIDMSVHYARILFISMPVLFLYFSYTTFIRGTGDSKTPFYFLIVSTVL
NIILLPILIFGWLGIPKLGVYGAAYASVISTVVTFIVMLIYLKKKNHPLQLDETVRKYLRMDWDLLKLLLRLGIPASINM
ILVSLSEIAVIAFVNRFGSDATAAYGVVNQVASYVQMPAVSLGITVSIFAAQSIGGKQFNRLQEVIRAGIIMNYIIGGIL
IAFIYLFSREILSLFLTNTNTVEIAHSLVMITLWSYLIFGHAQIIGATMRASGTVLWPTIIGVVSIWLVEVPVAYYLSYH
TNLGIKGIWIGYPAAFIVSLLLQYGYYKLSWKKKRISRLVS

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=404, Percent_Identity=21.7821782178218, Blast_Score=90, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 48910; Mature: 48779

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIFLVPLLLSNILQSVGQLFGMVVVGRWLGVNELAAISAFFPLFFLLVSFVIGIGSGSS
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ILIGQAFGARNEDRLKAIVGTTLTFTFIIGVILAIVGNVFALNIMRFMGTPENIIDMSVH
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
YARILFISMPVLFLYFSYTTFIRGTGDSKTPFYFLIVSTVLNIILLPILIFGWLGIPKLG
HHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
VYGAAYASVISTVVTFIVMLIYLKKKNHPLQLDETVRKYLRMDWDLLKLLLRLGIPASIN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCHHH
MILVSLSEIAVIAFVNRFGSDATAAYGVVNQVASYVQMPAVSLGITVSIFAAQSIGGKQF
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHCCEEEEEEHHHCCHHHH
NRLQEVIRAGIIMNYIIGGILIAFIYLFSREILSLFLTNTNTVEIAHSLVMITLWSYLIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
GHAQIIGATMRASGTVLWPTIIGVVSIWLVEVPVAYYLSYHTNLGIKGIWIGYPAAFIVS
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHH
LLLQYGYYKLSWKKKRISRLVS
HHHHCCCEEEEHHHHHHHHHCC
>Mature Secondary Structure 
SIFLVPLLLSNILQSVGQLFGMVVVGRWLGVNELAAISAFFPLFFLLVSFVIGIGSGSS
CEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ILIGQAFGARNEDRLKAIVGTTLTFTFIIGVILAIVGNVFALNIMRFMGTPENIIDMSVH
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
YARILFISMPVLFLYFSYTTFIRGTGDSKTPFYFLIVSTVLNIILLPILIFGWLGIPKLG
HHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
VYGAAYASVISTVVTFIVMLIYLKKKNHPLQLDETVRKYLRMDWDLLKLLLRLGIPASIN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCHHH
MILVSLSEIAVIAFVNRFGSDATAAYGVVNQVASYVQMPAVSLGITVSIFAAQSIGGKQF
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHCCEEEEEEHHHCCHHHH
NRLQEVIRAGIIMNYIIGGILIAFIYLFSREILSLFLTNTNTVEIAHSLVMITLWSYLIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
GHAQIIGATMRASGTVLWPTIIGVVSIWLVEVPVAYYLSYHTNLGIKGIWIGYPAAFIVS
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHH
LLLQYGYYKLSWKKKRISRLVS
HHHHCCCEEEEHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]