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The map label for this gene is adp [C]

Identifier: 222096620

GI number: 222096620

Start: 2894744

End: 2895871

Strand: Reverse

Name: adp [C]

Synonym: BCQ_2960

Alternate gene names: 222096620

Gene position: 2895871-2894744 (Counterclockwise)

Preceding gene: 222096622

Following gene: 222096619

Centisome position: 55.54

GC content: 39.36

Gene sequence:

>1128_bases
ATGAAAACACGCAGTAAAATTACATGTGCAAGTCTAGCACTTTTAATAGCTGGAAGTTCTCTGTTATACGTAACACCAAC
ATCCATTGTAAAAGCAGAACCTACGCAAAATGTAAATCGTACTTCCGTTAAGAAAGCAATGCGAGATGAACTGCAACTTG
GATACCCGGGAATACTCGCTAGCATTTCTAAGGGTGGTAAAACTTGGATTTATACTGCTGGGATAGCGGATCTGAGAACT
AAGAAACCAATGAAAGCAGATTTTCGCTTTCGCATTGGCAGTGTGACGAAAACGTTCATTGCAACAGTGCTCCTTCAATT
ATCTGGAGAGAACCGTTTGAATCTAGATGACTCCATTGAAAAATGGTTGCCTGGTGTCATTCAAGGAAACGGATATGATG
GTAACCAGATTACAATCCGGCAAATCATGAATCATACAAGTGGTATTGCTGACTATATAAATTCAAAAGACTTTGATATT
ACGGATATAAAAAAATCGTATACAGCTGAAGAATTTGTAAAGATGGGGATTTCTCTTCCCCCAGACTTTGCTCCAGGAAA
GGGTTGGTCTTATTCAAACACAGGATACGTATTACTGGGGATGCTTATTGAAAAAGTAACAGGAAACAGTTATGCGGAAG
AGGTTGAAAATCGGATTATTGAACCGCTTGATTTGTCAAATACATTCCTACCTGGCAATTCAAGCGTGATTCCAGGCACC
AAGCATGCCCGTGGCTATTTGCAACTAGACAAAGCGAGTGAGCTAAAAGACGTTACTTATATTAACCCAGGTAGCTCGGA
TGGAGATATGATTTCTACTGCTGACGACTTAAACAAATTCTTCTCTTACTTACTAGGTGGCAAATTACTGAAGGAACAGC
AATTAAAACAAATGCTTACTACAGTTCCTACAGAAAGAGAGGGAACTGGATATGGTCTTGGAATACTTGAAATTAAGCTT
CCAAATGGTGTCTCGGTATGGGGACACAGGGGAGCCGTTCCAGGGTTTTCCACTTTTGTTGGTGGAACACTTGGAGGTAA
ACATACACTCGCTATCAATGCGAACAGTTTAAACATTAATAATCCGGAATTTTTTAAAAATATTTTACTTGCTGAATTTA
GCAAGTAG

Upstream 100 bases:

>100_bases
TGTTGCCTTTTCATCAGTGGGAGAATGGATAATTGTGTGGTTCGTATAGGACACTGCTATCAACTATCTATACAATTTTA
ATAGAAGAGAGGAATTCTTT

Downstream 100 bases:

>100_bases
ACAAAAAGGAAAAACGGAAAAATTTTGTCATTTGTAATTTCAATCAGAATGGATTATCGCTTGAAATGAGTATAGAGGGG
ATTAAGTATATAGAAACAAT

Product: D-alanyl-D-alanine carboxypeptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase [H]

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MKTRSKITCASLALLIAGSSLLYVTPTSIVKAEPTQNVNRTSVKKAMRDELQLGYPGILASISKGGKTWIYTAGIADLRT
KKPMKADFRFRIGSVTKTFIATVLLQLSGENRLNLDDSIEKWLPGVIQGNGYDGNQITIRQIMNHTSGIADYINSKDFDI
TDIKKSYTAEEFVKMGISLPPDFAPGKGWSYSNTGYVLLGMLIEKVTGNSYAEEVENRIIEPLDLSNTFLPGNSSVIPGT
KHARGYLQLDKASELKDVTYINPGSSDGDMISTADDLNKFFSYLLGGKLLKEQQLKQMLTTVPTEREGTGYGLGILEIKL
PNGVSVWGHRGAVPGFSTFVGGTLGGKHTLAINANSLNINNPEFFKNILLAEFSK

Sequences:

>Translated_375_residues
MKTRSKITCASLALLIAGSSLLYVTPTSIVKAEPTQNVNRTSVKKAMRDELQLGYPGILASISKGGKTWIYTAGIADLRT
KKPMKADFRFRIGSVTKTFIATVLLQLSGENRLNLDDSIEKWLPGVIQGNGYDGNQITIRQIMNHTSGIADYINSKDFDI
TDIKKSYTAEEFVKMGISLPPDFAPGKGWSYSNTGYVLLGMLIEKVTGNSYAEEVENRIIEPLDLSNTFLPGNSSVIPGT
KHARGYLQLDKASELKDVTYINPGSSDGDMISTADDLNKFFSYLLGGKLLKEQQLKQMLTTVPTEREGTGYGLGILEIKL
PNGVSVWGHRGAVPGFSTFVGGTLGGKHTLAINANSLNINNPEFFKNILLAEFSK
>Mature_375_residues
MKTRSKITCASLALLIAGSSLLYVTPTSIVKAEPTQNVNRTSVKKAMRDELQLGYPGILASISKGGKTWIYTAGIADLRT
KKPMKADFRFRIGSVTKTFIATVLLQLSGENRLNLDDSIEKWLPGVIQGNGYDGNQITIRQIMNHTSGIADYINSKDFDI
TDIKKSYTAEEFVKMGISLPPDFAPGKGWSYSNTGYVLLGMLIEKVTGNSYAEEVENRIIEPLDLSNTFLPGNSSVIPGT
KHARGYLQLDKASELKDVTYINPGSSDGDMISTADDLNKFFSYLLGGKLLKEQQLKQMLTTVPTEREGTGYGLGILEIKL
PNGVSVWGHRGAVPGFSTFVGGTLGGKHTLAINANSLNINNPEFFKNILLAEFSK

Specific function: Catalyzes distinct carboxypeptidation and transpeptidation reactions during the last stages of wall peptidoglycan synthesis. Mistaking a beta-lactam antibiotic molecule for a normal substrate (i.e., a D-alanyl-D-alanine- terminated peptide), it becomes im

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S12 family [H]

Homologues:

Organism=Escherichia coli, GI1790593, Length=320, Percent_Identity=25.625, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI87082101, Length=245, Percent_Identity=25.3061224489796, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI115533026, Length=383, Percent_Identity=25.065274151436, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17550934, Length=314, Percent_Identity=26.1146496815287, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17565630, Length=224, Percent_Identity=27.2321428571429, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 40889; Mature: 40889

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTRSKITCASLALLIAGSSLLYVTPTSIVKAEPTQNVNRTSVKKAMRDELQLGYPGILA
CCCCHHHHHHHHHHHHHCCCEEEECCCHHEECCCCCCCCHHHHHHHHHHHHHCCCCHHHH
SISKGGKTWIYTAGIADLRTKKPMKADFRFRIGSVTKTFIATVLLQLSGENRLNLDDSIE
HHCCCCCEEEEECCCHHHHCCCCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCHHHH
KWLPGVIQGNGYDGNQITIRQIMNHTSGIADYINSKDFDITDIKKSYTAEEFVKMGISLP
HHCCCEEECCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCC
PDFAPGKGWSYSNTGYVLLGMLIEKVTGNSYAEEVENRIIEPLDLSNTFLPGNSSVIPGT
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
KHARGYLQLDKASELKDVTYINPGSSDGDMISTADDLNKFFSYLLGGKLLKEQQLKQMLT
CCCCCEEEECCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
TVPTEREGTGYGLGILEIKLPNGVSVWGHRGAVPGFSTFVGGTLGGKHTLAINANSLNIN
HCCCCCCCCCCCEEEEEEECCCCCEECCCCCCCCCHHHHHCCCCCCCEEEEEECCCCCCC
NPEFFKNILLAEFSK
CHHHHHHHHHHHCCC
>Mature Secondary Structure
MKTRSKITCASLALLIAGSSLLYVTPTSIVKAEPTQNVNRTSVKKAMRDELQLGYPGILA
CCCCHHHHHHHHHHHHHCCCEEEECCCHHEECCCCCCCCHHHHHHHHHHHHHCCCCHHHH
SISKGGKTWIYTAGIADLRTKKPMKADFRFRIGSVTKTFIATVLLQLSGENRLNLDDSIE
HHCCCCCEEEEECCCHHHHCCCCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCHHHH
KWLPGVIQGNGYDGNQITIRQIMNHTSGIADYINSKDFDITDIKKSYTAEEFVKMGISLP
HHCCCEEECCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCC
PDFAPGKGWSYSNTGYVLLGMLIEKVTGNSYAEEVENRIIEPLDLSNTFLPGNSSVIPGT
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
KHARGYLQLDKASELKDVTYINPGSSDGDMISTADDLNKFFSYLLGGKLLKEQQLKQMLT
CCCCCEEEECCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
TVPTEREGTGYGLGILEIKLPNGVSVWGHRGAVPGFSTFVGGTLGGKHTLAINANSLNIN
HCCCCCCCCCCCEEEEEEECCCCCEECCCCCCCCCHHHHHCCCCCCCEEEEEECCCCCCC
NPEFFKNILLAEFSK
CHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3830154; 7925404; 3030739; 2175384; 2386365; 3997832; 7490745 [H]