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The map label for this gene is yclK [H]

Identifier: 222096357

GI number: 222096357

Start: 2637535

End: 2638911

Strand: Reverse

Name: yclK [H]

Synonym: BCQ_2697

Alternate gene names: 222096357

Gene position: 2638911-2637535 (Counterclockwise)

Preceding gene: 222096358

Following gene: 222096356

Centisome position: 50.61

GC content: 29.63

Gene sequence:

>1377_bases
GTGAATAAACTTGGAAAAAAGCTATTTCTCAGCATTTCTTTAACTGTTATTCTTATTTTTACGATCTCTTTATTAATAAT
TAACTATCTTTTACCGAAATATAATATTTACAAAACGAGAGAGAACTTGAATGAATTTACAGTGCAAATACAAAATACAT
CTGTAAATGAGTTAGAAGATGTAATTCGTACAATTGAAAGCGAAAATAACGTTACGTTTGCATATACGTCAATCAATCAG
TCAGAAGATGATATGAACGAAGCGTTACGCATGCAACTTACGAAAAAGAAAGTAGTTTTAAATAAACTGTGGATTACGAA
AGACGCAGTCATGAAGGTGAAAGCGGAAGGGCAATCGAATAAACTGTATGATCAAGAGAAGTTAAAAGCAAGTTTTTTCG
CTAAATATATTGCAAAAGATAATACAATAATTTTAATGGGAACTTCTATTGCACATTCTAACGAAATTATAAAAACGTTA
AATACATTTTATTTATACATTCTTTGTTTCTCACTCCTTCTTATTATTTTACTTGTGTGGATACTTTCAAAAATAATAAC
GACTCCATTGAAAGATCTAAGCGATGTAGCTCAGGATATTTCACATTTGAAGTTTAAAAGAACGAAAGTGAAAACGAATG
ATGAAATAGGAGAATTAGCCAATAGCATTAATATTATGAGTGAAAAACTACATGAAGCACATCAAGATTTAACAGATCGT
AATGAACATTTAAAACGATTTATGGGTGATGTGACGCATGAATTAAAGACACCAATTGCATTAGTAAAAGCATATTCTAT
GGGAATTAAGGATGGATTGGATGATGGGACATACGTAGATACAATTATTAAACAAACAGATCAAATATCAAACTTAATTG
AAGAACTATTACGATTTTCGAAGTTAGAAAGAGATGTTTTACAAAAAGAAGAATTCCCTATTGAACCATTAGTCCGAAGT
ATAATAGATAAGCATAAAATTGAACTGGAGTCGAAAGAAATACAGTTGCAGACGAACAGTAATATTAAAAATCAGGTCAT
TTATGCGGATTTAAATAAAATGGGAATGGTGTTTCAAAATTTAATTTCAAACGCAATAAAATATACAACAAATCAAAACA
TAATAATCACTTTAGAAGAGAGAAATAATAGTGTATATTTTCAAATTAAAAATGGGATTAATGCAGAACAAATTAAAGAT
GTCGATAAAATTTGGGAACCTTTTTATGTCTTAGACTCTTCGCGAAGTAAAGAAAAATCAGGCACAGGATTAGGACTAGC
GATAGTGAAAAGTATTTTAGAAAGGCATGGTTTTGACTATGGCGTATCTACTAAAGAGGGAGAAATACGGTTTTATATTA
CTATGAAGAATGACTAA

Upstream 100 bases:

>100_bases
GAGCGAACTGTTGATACACATGTAAGAAGGTTACGTAAAAAAGTAGGAGAAAATATTATAAAGACGCATCGTGGTTTAGG
GTATAGTTTGGAGGAGCAGA

Downstream 100 bases:

>100_bases
TTCAATACAATTAGAAGCATCGTCTATTAATAGGTGATGTTTTTTATTGATTATATGAGAGCAGTAAATCAGAATATATA
ACCTTGAAAGCCCGTTGGAA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MNKLGKKLFLSISLTVILIFTISLLIINYLLPKYNIYKTRENLNEFTVQIQNTSVNELEDVIRTIESENNVTFAYTSINQ
SEDDMNEALRMQLTKKKVVLNKLWITKDAVMKVKAEGQSNKLYDQEKLKASFFAKYIAKDNTIILMGTSIAHSNEIIKTL
NTFYLYILCFSLLLIILLVWILSKIITTPLKDLSDVAQDISHLKFKRTKVKTNDEIGELANSINIMSEKLHEAHQDLTDR
NEHLKRFMGDVTHELKTPIALVKAYSMGIKDGLDDGTYVDTIIKQTDQISNLIEELLRFSKLERDVLQKEEFPIEPLVRS
IIDKHKIELESKEIQLQTNSNIKNQVIYADLNKMGMVFQNLISNAIKYTTNQNIIITLEERNNSVYFQIKNGINAEQIKD
VDKIWEPFYVLDSSRSKEKSGTGLGLAIVKSILERHGFDYGVSTKEGEIRFYITMKND

Sequences:

>Translated_458_residues
MNKLGKKLFLSISLTVILIFTISLLIINYLLPKYNIYKTRENLNEFTVQIQNTSVNELEDVIRTIESENNVTFAYTSINQ
SEDDMNEALRMQLTKKKVVLNKLWITKDAVMKVKAEGQSNKLYDQEKLKASFFAKYIAKDNTIILMGTSIAHSNEIIKTL
NTFYLYILCFSLLLIILLVWILSKIITTPLKDLSDVAQDISHLKFKRTKVKTNDEIGELANSINIMSEKLHEAHQDLTDR
NEHLKRFMGDVTHELKTPIALVKAYSMGIKDGLDDGTYVDTIIKQTDQISNLIEELLRFSKLERDVLQKEEFPIEPLVRS
IIDKHKIELESKEIQLQTNSNIKNQVIYADLNKMGMVFQNLISNAIKYTTNQNIIITLEERNNSVYFQIKNGINAEQIKD
VDKIWEPFYVLDSSRSKEKSGTGLGLAIVKSILERHGFDYGVSTKEGEIRFYITMKND
>Mature_458_residues
MNKLGKKLFLSISLTVILIFTISLLIINYLLPKYNIYKTRENLNEFTVQIQNTSVNELEDVIRTIESENNVTFAYTSINQ
SEDDMNEALRMQLTKKKVVLNKLWITKDAVMKVKAEGQSNKLYDQEKLKASFFAKYIAKDNTIILMGTSIAHSNEIIKTL
NTFYLYILCFSLLLIILLVWILSKIITTPLKDLSDVAQDISHLKFKRTKVKTNDEIGELANSINIMSEKLHEAHQDLTDR
NEHLKRFMGDVTHELKTPIALVKAYSMGIKDGLDDGTYVDTIIKQTDQISNLIEELLRFSKLERDVLQKEEFPIEPLVRS
IIDKHKIELESKEIQLQTNSNIKNQVIYADLNKMGMVFQNLISNAIKYTTNQNIIITLEERNNSVYFQIKNGINAEQIKD
VDKIWEPFYVLDSSRSKEKSGTGLGLAIVKSILERHGFDYGVSTKEGEIRFYITMKND

Specific function: Could be member of the two-component regulatory system yclK/yclJ. Potentially phosphorylates yclJ [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=259, Percent_Identity=26.2548262548263, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1789149, Length=323, Percent_Identity=26.0061919504644, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1788279, Length=278, Percent_Identity=26.2589928057554, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790346, Length=214, Percent_Identity=22.8971962616822, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790436, Length=230, Percent_Identity=27.3913043478261, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787894, Length=212, Percent_Identity=27.8301886792453, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786783, Length=300, Percent_Identity=25.3333333333333, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87082128, Length=300, Percent_Identity=22.6666666666667, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1786600, Length=204, Percent_Identity=25, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI48994928, Length=225, Percent_Identity=25.3333333333333, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI145693157, Length=234, Percent_Identity=27.3504273504274, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1790861, Length=272, Percent_Identity=23.8970588235294, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 52740; Mature: 52740

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLGKKLFLSISLTVILIFTISLLIINYLLPKYNIYKTRENLNEFTVQIQNTSVNELED
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCEEEEEECCCHHHHHH
VIRTIESENNVTFAYTSINQSEDDMNEALRMQLTKKKVVLNKLWITKDAVMKVKAEGQSN
HHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEECCCCCC
KLYDQEKLKASFFAKYIAKDNTIILMGTSIAHSNEIIKTLNTFYLYILCFSLLLIILLVW
CCCCHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILSKIITTPLKDLSDVAQDISHLKFKRTKVKTNDEIGELANSINIMSEKLHEAHQDLTDR
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCH
NEHLKRFMGDVTHELKTPIALVKAYSMGIKDGLDDGTYVDTIIKQTDQISNLIEELLRFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KLERDVLQKEEFPIEPLVRSIIDKHKIELESKEIQLQTNSNIKNQVIYADLNKMGMVFQN
HHHHHHHHHCCCCHHHHHHHHHHHHHEEECCCEEEEEECCCCCCEEEEECHHHHHHHHHH
LISNAIKYTTNQNIIITLEERNNSVYFQIKNGINAEQIKDVDKIWEPFYVLDSSRSKEKS
HHHHHHHCCCCCCEEEEEEECCCEEEEEECCCCCHHHHHHHHHHCCCEEEECCCCCCCCC
GTGLGLAIVKSILERHGFDYGVSTKEGEIRFYITMKND
CCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCC
>Mature Secondary Structure
MNKLGKKLFLSISLTVILIFTISLLIINYLLPKYNIYKTRENLNEFTVQIQNTSVNELED
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCEEEEEECCCHHHHHH
VIRTIESENNVTFAYTSINQSEDDMNEALRMQLTKKKVVLNKLWITKDAVMKVKAEGQSN
HHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEECCCCCC
KLYDQEKLKASFFAKYIAKDNTIILMGTSIAHSNEIIKTLNTFYLYILCFSLLLIILLVW
CCCCHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILSKIITTPLKDLSDVAQDISHLKFKRTKVKTNDEIGELANSINIMSEKLHEAHQDLTDR
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCH
NEHLKRFMGDVTHELKTPIALVKAYSMGIKDGLDDGTYVDTIIKQTDQISNLIEELLRFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KLERDVLQKEEFPIEPLVRSIIDKHKIELESKEIQLQTNSNIKNQVIYADLNKMGMVFQN
HHHHHHHHHCCCCHHHHHHHHHHHHHEEECCCEEEEEECCCCCCEEEEECHHHHHHHHHH
LISNAIKYTTNQNIIITLEERNNSVYFQIKNGINAEQIKDVDKIWEPFYVLDSSRSKEKS
HHHHHHHCCCCCCEEEEEEECCCEEEEEECCCCCHHHHHHHHHHCCCEEEECCCCCCCCC
GTGLGLAIVKSILERHGFDYGVSTKEGEIRFYITMKND
CCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]