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The map label for this gene is phoP [H]

Identifier: 222096358

GI number: 222096358

Start: 2638904

End: 2639551

Strand: Reverse

Name: phoP [H]

Synonym: BCQ_2698

Alternate gene names: 222096358

Gene position: 2639551-2638904 (Counterclockwise)

Preceding gene: 222096360

Following gene: 222096357

Centisome position: 50.62

GC content: 31.79

Gene sequence:

>648_bases
ATGAAAGTATTAATCGCAGATGATGAACAAGATATGCTAAGGATTTTAAAAGCTTATTTTGAAAAAGAAGATTTCGAAGT
GTTATTAGCGAAAGATGGAGAGGAAGCACTTCAAATATTTTATGATGAGAAAATTGATTTAGCTATTTTAGATTGGATGA
TGCCGAAATATAGTGGCATTACTGTCTGTCAGGAAATAAAAAAGAATTCAAGCGTAAAAGTATTAATGCTTACGGCGAAA
AGTGAAAGCGAAGATGAATTAGCAGCGCTTCAAAGCGGGGCAGATGAGTATGTAAAAAAACCATTTCATCCAGGCGTATT
AATCACTAGAGCGAAAAAGCTTATACAGCATGATGATGTCATTCAAGTTCAAGATTTGAAAATAGATTTTACGAAAAATA
AAGTTTATAAAAATGACAAAGAGTTAGATATTACAAAAACAGAGCTAGAATTAATAAAGTGTTTTTTAAATCATAAAGGC
ATGATTTTAACTCGTAAAAAATTGTTAGATATCGTATGGGGATTTGACTATTTTGGAGAAGAGCGAACTGTTGATACACA
TGTAAGAAGGTTACGTAAAAAAGTAGGAGAAAATATTATAAAGACGCATCGTGGTTTAGGGTATAGTTTGGAGGAGCAGA
GTGAATAA

Upstream 100 bases:

>100_bases
TATACCCTTAACTAGTTCAAATATTTTTCTGTCACATACATGTAACAAAGAAGTTGTATGATACAATTAATTTTTGTTTA
AAAGCAATGGAGGATAATGT

Downstream 100 bases:

>100_bases
ACTTGGAAAAAAGCTATTTCTCAGCATTTCTTTAACTGTTATTCTTATTTTTACGATCTCTTTATTAATAATTAACTATC
TTTTACCGAAATATAATATT

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MKVLIADDEQDMLRILKAYFEKEDFEVLLAKDGEEALQIFYDEKIDLAILDWMMPKYSGITVCQEIKKNSSVKVLMLTAK
SESEDELAALQSGADEYVKKPFHPGVLITRAKKLIQHDDVIQVQDLKIDFTKNKVYKNDKELDITKTELELIKCFLNHKG
MILTRKKLLDIVWGFDYFGEERTVDTHVRRLRKKVGENIIKTHRGLGYSLEEQSE

Sequences:

>Translated_215_residues
MKVLIADDEQDMLRILKAYFEKEDFEVLLAKDGEEALQIFYDEKIDLAILDWMMPKYSGITVCQEIKKNSSVKVLMLTAK
SESEDELAALQSGADEYVKKPFHPGVLITRAKKLIQHDDVIQVQDLKIDFTKNKVYKNDKELDITKTELELIKCFLNHKG
MILTRKKLLDIVWGFDYFGEERTVDTHVRRLRKKVGENIIKTHRGLGYSLEEQSE
>Mature_215_residues
MKVLIADDEQDMLRILKAYFEKEDFEVLLAKDGEEALQIFYDEKIDLAILDWMMPKYSGITVCQEIKKNSSVKVLMLTAK
SESEDELAALQSGADEYVKKPFHPGVLITRAKKLIQHDDVIQVQDLKIDFTKNKVYKNDKELDITKTELELIKCFLNHKG
MILTRKKLLDIVWGFDYFGEERTVDTHVRRLRKKVGENIIKTHRGLGYSLEEQSE

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=220, Percent_Identity=34.0909090909091, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=28.4444444444444, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=33.4841628959276, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1786911, Length=219, Percent_Identity=30.1369863013699, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1788394, Length=222, Percent_Identity=30.1801801801802, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=31.0810810810811, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=28.4403669724771, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1787229, Length=221, Percent_Identity=26.2443438914027, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI2367329, Length=225, Percent_Identity=30.2222222222222, Blast_Score=100, Evalue=5e-23,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=30.3964757709251, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=27.1493212669683, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI145693140, Length=228, Percent_Identity=27.1929824561404, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=29.0178571428571, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1789402, Length=219, Percent_Identity=26.027397260274, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1788550, Length=102, Percent_Identity=36.2745098039216, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1788191, Length=120, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1790437, Length=101, Percent_Identity=34.6534653465347, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25014; Mature: 25014

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLIADDEQDMLRILKAYFEKEDFEVLLAKDGEEALQIFYDEKIDLAILDWMMPKYSGI
CEEEEECCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCCHHHHHHHCCCCCCH
TVCQEIKKNSSVKVLMLTAKSESEDELAALQSGADEYVKKPFHPGVLITRAKKLIQHDDV
HHHHHHHCCCCEEEEEEEECCCCHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHCCCCC
IQVQDLKIDFTKNKVYKNDKELDITKTELELIKCFLNHKGMILTRKKLLDIVWGFDYFGE
EEEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCHHHCCC
ERTVDTHVRRLRKKVGENIIKTHRGLGYSLEEQSE
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKVLIADDEQDMLRILKAYFEKEDFEVLLAKDGEEALQIFYDEKIDLAILDWMMPKYSGI
CEEEEECCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCCHHHHHHHCCCCCCH
TVCQEIKKNSSVKVLMLTAKSESEDELAALQSGADEYVKKPFHPGVLITRAKKLIQHDDV
HHHHHHHCCCCEEEEEEEECCCCHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHCCCCC
IQVQDLKIDFTKNKVYKNDKELDITKTELELIKCFLNHKGMILTRKKLLDIVWGFDYFGE
EEEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCHHHCCC
ERTVDTHVRRLRKKVGENIIKTHRGLGYSLEEQSE
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]