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The map label for this gene is rrmA [C]

Identifier: 222095744

GI number: 222095744

Start: 2054670

End: 2055299

Strand: Direct

Name: rrmA [C]

Synonym: BCQ_2084

Alternate gene names: 222095744

Gene position: 2054670-2055299 (Clockwise)

Preceding gene: 222095742

Following gene: 222095745

Centisome position: 39.41

GC content: 37.62

Gene sequence:

>630_bases
ATGTGGGATAGTGGGAGTAGGAGTACGATTATTCCATTTTTTGAACAATATGTGAAGAAAGAAGCCAAGGTGCTTGACGT
TGGTTGTGGAGATGGATACGGTACATATAAATTAAGTCGCGCGGGCTATAAAGCAGTTGGAGTAGATTTATCAGAAGTGA
TGATTCAAAAAGGGAAGGAGCGCGGAGAGGGACCGGATTTATCCTTTATAAAAGGAGATCTTTCTTCCTTACCGTTCGAA
AATGAACAATTTGAAGCAATTATGGCAATTAATTCTTTAGAATGGACCGAGGAGCCATTACGAGCATTAAATGAGATAAA
GCGTGTTCTAAAAAGTGATGGGTATGCATGTATTGCAATTTTAGGGCCGACAGCAAAGCCAAGAGAGAACAGTTATCCTC
GTTTATACGGCAAAGACGTTGTATGTAATACGATGATGCCTTGGGAATTTGAACAGTTAGCAAAAGAACAAGGTTTTAAA
GTTGTAGATGGTATCGGTGTATATAAGCGCGGAGTAAATGAGAAGATGTTAGGTCAACTATCTACAGAGTTACAACAATC
GTTAACGTTCTTATGGGTATTTATGTTAAAAAAGCATAAAGAAATGAAAGAATTTTTAGGAGGTAAATAA

Upstream 100 bases:

>100_bases
CGTGAAGGTAGGGGAATGTATGACGAAATTTAATTGGCATGAATCAGCAGAGAAGAAATGGGATAGTAGTGCAGAGTTTT
GGAATCAAAATAGTCAGGAG

Downstream 100 bases:

>100_bases
GTGCAGAAAATACAAAAAACTGATACAATATCATCAGAACCAATTAAAGGGGGACTAGGGTATATGACAACTACTACAAC
AGTTAAATCCGACATTGAAA

Product: methyltransferase

Products: S-adenosyl-L-homocysteine +rRNA containing Nmethylguanine [C]

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MWDSGSRSTIIPFFEQYVKKEAKVLDVGCGDGYGTYKLSRAGYKAVGVDLSEVMIQKGKERGEGPDLSFIKGDLSSLPFE
NEQFEAIMAINSLEWTEEPLRALNEIKRVLKSDGYACIAILGPTAKPRENSYPRLYGKDVVCNTMMPWEFEQLAKEQGFK
VVDGIGVYKRGVNEKMLGQLSTELQQSLTFLWVFMLKKHKEMKEFLGGK

Sequences:

>Translated_209_residues
MWDSGSRSTIIPFFEQYVKKEAKVLDVGCGDGYGTYKLSRAGYKAVGVDLSEVMIQKGKERGEGPDLSFIKGDLSSLPFE
NEQFEAIMAINSLEWTEEPLRALNEIKRVLKSDGYACIAILGPTAKPRENSYPRLYGKDVVCNTMMPWEFEQLAKEQGFK
VVDGIGVYKRGVNEKMLGQLSTELQQSLTFLWVFMLKKHKEMKEFLGGK
>Mature_209_residues
MWDSGSRSTIIPFFEQYVKKEAKVLDVGCGDGYGTYKLSRAGYKAVGVDLSEVMIQKGKERGEGPDLSFIKGDLSSLPFE
NEQFEAIMAINSLEWTEEPLRALNEIKRVLKSDGYACIAILGPTAKPRENSYPRLYGKDVVCNTMMPWEFEQLAKEQGFK
VVDGIGVYKRGVNEKMLGQLSTELQQSLTFLWVFMLKKHKEMKEFLGGK

Specific function: Catalyzes the methylation of the lipid moiety of the intermediate compounds phthiotriol and glycosylated phenolphthiotriol dimycoserosates to form phthiocerol dimycocerosates (DIM A) and glycosylated phenolphthiocerol dimycocerosates (PGL) [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. Phthiotriol/phenolphthiotriol dimycocerosates methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: 2.1.1.51 [C]

Molecular weight: Translated: 23614; Mature: 23614

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWDSGSRSTIIPFFEQYVKKEAKVLDVGCGDGYGTYKLSRAGYKAVGVDLSEVMIQKGKE
CCCCCCCCCCHHHHHHHHHHHHHEEECCCCCCCCCEEECCCCCHHHCCCHHHHHHHHCCC
RGEGPDLSFIKGDLSSLPFENEQFEAIMAINSLEWTEEPLRALNEIKRVLKSDGYACIAI
CCCCCCHHHHHCHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEE
LGPTAKPRENSYPRLYGKDVVCNTMMPWEFEQLAKEQGFKVVDGIGVYKRGVNEKMLGQL
ECCCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHCCCEEECCHHHHHHCCCHHHHHHH
STELQQSLTFLWVFMLKKHKEMKEFLGGK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MWDSGSRSTIIPFFEQYVKKEAKVLDVGCGDGYGTYKLSRAGYKAVGVDLSEVMIQKGKE
CCCCCCCCCCHHHHHHHHHHHHHEEECCCCCCCCCEEECCCCCHHHCCCHHHHHHHHCCC
RGEGPDLSFIKGDLSSLPFENEQFEAIMAINSLEWTEEPLRALNEIKRVLKSDGYACIAI
CCCCCCHHHHHCHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEE
LGPTAKPRENSYPRLYGKDVVCNTMMPWEFEQLAKEQGFKVVDGIGVYKRGVNEKMLGQL
ECCCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHCCCEEECCHHHHHHCCCHHHHHHH
STELQQSLTFLWVFMLKKHKEMKEFLGGK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Unidentified protein factor B [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-methionine; rRNA [C]

Specific reaction: S-Adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine +rRNA containing Nmethylguanine [C]

General reaction: Methyl group transfer [C]

Inhibitor: Mg2+; Unidentified protein factor A1 [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]