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The map label for this gene is cobW [H]

Identifier: 222095576

GI number: 222095576

Start: 1896472

End: 1897317

Strand: Direct

Name: cobW [H]

Synonym: BCQ_1916

Alternate gene names: 222095576

Gene position: 1896472-1897317 (Clockwise)

Preceding gene: 222095575

Following gene: 222095577

Centisome position: 36.37

GC content: 32.74

Gene sequence:

>846_bases
TTGTTAGCAGAGAAAAAGAAGAATAGAAAAGTTGCAGTATTAATGAATGAAATTGGTGAATACTCAGTAGATACAGATAT
TATTGGAAAAGAGAATGTTTTAAGAGAACTTCTTAAAGGATGTATTTGTTGTACGTTAAAAGAAGAGCTTGAAATACAAT
TACATTCGTTATACCAGCAAGAAAGACCAGATGTCATTTATATAGAAACGACAGGTGTTGCGCATCCAATTGAAGTACTA
GATGCATGTGTATCACCAATTTTAGCACCGTTCTTAGAAGTGAAATCAATAGTAGTCGTTTTAGATGCAGTAAGGTGGTT
AAATCGAAGTATATTAAGTGCAAATGTGCAACAGCTACTGCATGAGCAAATGAAATTTGGTAGCCATATTTTAATTAATA
AATCAGATTTACTAACAGATGCGGATAAGAAGAAAGTAATTGAAGACGTGAAAGCAATAAATAATCATGCAAAATTGTTT
GAAACAAAATATTGTAATATATCTTTAGAAGATATAGAAGAAGCTGAATTTATGAATGATGGGGAACATGAGACACTACA
TGTCAAACAGCATTTACATATACAAACGATGACATATCAATTTACGAAATCGATTGATCAAGACAATTTATATGAATGGC
TTTCAAATTTACCAGATAGTATTTATCGTGTAAAAGGTTTTGTGAAATTTCATGGGGACAAATATCCTCACTTATTCCAA
TACTCGTTCGGAGTACCGACTTTACTGGAACAAGACTTCGGTTTCCCAACGAACTTAGTAGTAATAGGGGAAGGGCTAGA
TAAGAAGCGATTGGCTGAAGGGTTAGAGGAAGTGGAAAATAATTAA

Upstream 100 bases:

>100_bases
TGAAGTAAAGAAATGGATGGTCGGTTGAATGAATAAAGTGGAGATTCATATATTAGGTGGTTTTTTAGGTAGTGGAAAAT
CAACATTATTACAAAATTTA

Downstream 100 bases:

>100_bases
GTGTTTTTTACATAGGCTGCAATAATTGACTTAAGAACTTAAGTTAATTATTGTAGCTTTTTTCATGATTAATACTGCAA
CGAAACAGTATTTTCAATTG

Product: gtpase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MLAEKKKNRKVAVLMNEIGEYSVDTDIIGKENVLRELLKGCICCTLKEELEIQLHSLYQQERPDVIYIETTGVAHPIEVL
DACVSPILAPFLEVKSIVVVLDAVRWLNRSILSANVQQLLHEQMKFGSHILINKSDLLTDADKKKVIEDVKAINNHAKLF
ETKYCNISLEDIEEAEFMNDGEHETLHVKQHLHIQTMTYQFTKSIDQDNLYEWLSNLPDSIYRVKGFVKFHGDKYPHLFQ
YSFGVPTLLEQDFGFPTNLVVIGEGLDKKRLAEGLEEVENN

Sequences:

>Translated_281_residues
MLAEKKKNRKVAVLMNEIGEYSVDTDIIGKENVLRELLKGCICCTLKEELEIQLHSLYQQERPDVIYIETTGVAHPIEVL
DACVSPILAPFLEVKSIVVVLDAVRWLNRSILSANVQQLLHEQMKFGSHILINKSDLLTDADKKKVIEDVKAINNHAKLF
ETKYCNISLEDIEEAEFMNDGEHETLHVKQHLHIQTMTYQFTKSIDQDNLYEWLSNLPDSIYRVKGFVKFHGDKYPHLFQ
YSFGVPTLLEQDFGFPTNLVVIGEGLDKKRLAEGLEEVENN
>Mature_281_residues
MLAEKKKNRKVAVLMNEIGEYSVDTDIIGKENVLRELLKGCICCTLKEELEIQLHSLYQQERPDVIYIETTGVAHPIEVL
DACVSPILAPFLEVKSIVVVLDAVRWLNRSILSANVQQLLHEQMKFGSHILINKSDLLTDADKKKVIEDVKAINNHAKLF
ETKYCNISLEDIEEAEFMNDGEHETLHVKQHLHIQTMTYQFTKSIDQDNLYEWLSNLPDSIYRVKGFVKFHGDKYPHLFQ
YSFGVPTLLEQDFGFPTNLVVIGEGLDKKRLAEGLEEVENN

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI126722884, Length=305, Percent_Identity=24.9180327868852, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI223941776, Length=300, Percent_Identity=25, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI33469141, Length=305, Percent_Identity=24.9180327868852, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI148727351, Length=305, Percent_Identity=25.2459016393443, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1788499, Length=140, Percent_Identity=32.1428571428571, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI87082430, Length=269, Percent_Identity=26.3940520446097, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 32241; Mature: 32241

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAEKKKNRKVAVLMNEIGEYSVDTDIIGKENVLRELLKGCICCTLKEELEIQLHSLYQQ
CCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERPDVIYIETTGVAHPIEVLDACVSPILAPFLEVKSIVVVLDAVRWLNRSILSANVQQLL
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HEQMKFGSHILINKSDLLTDADKKKVIEDVKAINNHAKLFETKYCNISLEDIEEAEFMND
HHHHHCCCEEEEECHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
GEHETLHVKQHLHIQTMTYQFTKSIDQDNLYEWLSNLPDSIYRVKGFVKFHGDKYPHLFQ
CCCCEEEEHHHEEHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHEECCCCCCCEEE
YSFGVPTLLEQDFGFPTNLVVIGEGLDKKRLAEGLEEVENN
ECCCCCHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MLAEKKKNRKVAVLMNEIGEYSVDTDIIGKENVLRELLKGCICCTLKEELEIQLHSLYQQ
CCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERPDVIYIETTGVAHPIEVLDACVSPILAPFLEVKSIVVVLDAVRWLNRSILSANVQQLL
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HEQMKFGSHILINKSDLLTDADKKKVIEDVKAINNHAKLFETKYCNISLEDIEEAEFMND
HHHHHCCCEEEEECHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
GEHETLHVKQHLHIQTMTYQFTKSIDQDNLYEWLSNLPDSIYRVKGFVKFHGDKYPHLFQ
CCCCEEEEHHHEEHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHEECCCCCCCEEE
YSFGVPTLLEQDFGFPTNLVVIGEGLDKKRLAEGLEEVENN
ECCCCCHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]