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The map label for this gene is recQ [H]

Identifier: 222095214

GI number: 222095214

Start: 1529486

End: 1530883

Strand: Direct

Name: recQ [H]

Synonym: BCQ_1554

Alternate gene names: 222095214

Gene position: 1529486-1530883 (Clockwise)

Preceding gene: 222095213

Following gene: 222095215

Centisome position: 29.33

GC content: 35.34

Gene sequence:

>1398_bases
ATGTGCTATCAACTTCCAGGGCTCATGCAAGAAGGGACAGTACTTGTTGTATCACCATTATTATCTTTGATGGAAGATCA
GGTTACACAATTAAAATATGTTGTGAAAAACCGAGTGATAGCATTTAATAGTTTTCGGACATTACAGGAAAAAAGAGAAG
CGATGAAAAGATTAGCTTCTTATAAATTTATTTTTGTATCACCAGAGATGTTGCAGTCGGAATTGTTAATAAGAGAATTG
AAGAAAGTTCATATTTCATTATTTGTTGTGGATGAAGCTCATTGTATTTCGCAATGGGGTTATGATTTTAGACCAGATTA
TAAAAAACTAGATGTAGTTATTAAGAATATCGGGTCTCCTACGGTGCTAGCATTAACTGCAACAGCGACGAAAGATGTAC
TCCGAGATATAGCAGAGAGTTTGAATTTGGAGAATGTGACGCAGCATGTGTATTCTATTGATCGTCCAAATATAGCAATG
GAAGTACAATTTGTAGAGACGATAGAAGAGAAGAAAGAGGCGCTTTTGGACCAGGTGATGTATTTACAAGGGCCGGGGAT
TGTATATTGTTCAAGCAGAGCGTGGACAGAACGTTTAACGGAATATTTAAGAGGAAAAGGCGTTACTGGTGTCGCTTTCT
ATCATGGTGGTATGGAACATGAAGAGCGTATGTTAATTCAACAGCAGTTTATGAATGACCAATTACAGCTTGTAATATGT
ACAAGTGCTTTTGGTATGGGAGTAAATAAATCGAACACGAGATATATTATTCATTTTCACTATCCGACTAATATAGCTTC
TTATTTACAAGAAATCGGAAGAGCTGGAAGAGATGGTGAACCAAGTATAGCTATTTTACTATGTAGTCCGTTAGATCACG
ATTTACCAATTTCAATCATTGAAGATGAATTGCCAAGCCAGTCACAAATACAATTTTTATTTTCTTTACTGCAGGAAAGA
ATGTTTCAAACGAAAGAATTACCAATAGAAGAGGTAGAAGAAATTTGTTATAATGCAGCAAGATTTAATGAACAATATTG
GCGTTTCATCCGCTATCATCTTGAACAGCTTGGAATCATACAACAACGAAAACTAATATTAGAGAGCTTGTCAGATGAAA
TTATGAACAGATTAATAGCTGAAGTAGAAATAAGGTTACGTAATAAATATAGTGAGCTAGAAAACATGAAATCATGGATA
CAAGTGAAAGAATGTAGACGAGAATATTTGCTGCGACAGTTCGGTTACAGAAAAGAGGGCGAGGTAAAGAATTGCTGCGA
CTATTGTCATATTACAAAAACAGATTATAAAAAAAGACAAGCGCAACAATCGGATTTCGACTATAATTGGGAAACAGAGT
TACAAAAGCTTTTCGGTCTAGAAAAGATGGGGGAATGA

Upstream 100 bases:

>100_bases
TGGATATTCTGAATTTCGTCCAGGTCAAAAAGGGGTAATTACAGATTTATTGGAAGGAAAAGATGTTATAGCGATGCTTC
CGACCGGAAGAGGGAAGTCT

Downstream 100 bases:

>100_bases
TGAACATTCAAAGGCATAATATTGAAGATATGAGTCCGAAAGAAATAAGGCTGAATCTGTATATCACACAGTTCATTATT
ATCGGTATCGGTTGTTTACT

Product: ATP-dependent DNA helicase q

Products: NA

Alternate protein names: Recombination protein S [H]

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MCYQLPGLMQEGTVLVVSPLLSLMEDQVTQLKYVVKNRVIAFNSFRTLQEKREAMKRLASYKFIFVSPEMLQSELLIREL
KKVHISLFVVDEAHCISQWGYDFRPDYKKLDVVIKNIGSPTVLALTATATKDVLRDIAESLNLENVTQHVYSIDRPNIAM
EVQFVETIEEKKEALLDQVMYLQGPGIVYCSSRAWTERLTEYLRGKGVTGVAFYHGGMEHEERMLIQQQFMNDQLQLVIC
TSAFGMGVNKSNTRYIIHFHYPTNIASYLQEIGRAGRDGEPSIAILLCSPLDHDLPISIIEDELPSQSQIQFLFSLLQER
MFQTKELPIEEVEEICYNAARFNEQYWRFIRYHLEQLGIIQQRKLILESLSDEIMNRLIAEVEIRLRNKYSELENMKSWI
QVKECRREYLLRQFGYRKEGEVKNCCDYCHITKTDYKKRQAQQSDFDYNWETELQKLFGLEKMGE

Sequences:

>Translated_465_residues
MCYQLPGLMQEGTVLVVSPLLSLMEDQVTQLKYVVKNRVIAFNSFRTLQEKREAMKRLASYKFIFVSPEMLQSELLIREL
KKVHISLFVVDEAHCISQWGYDFRPDYKKLDVVIKNIGSPTVLALTATATKDVLRDIAESLNLENVTQHVYSIDRPNIAM
EVQFVETIEEKKEALLDQVMYLQGPGIVYCSSRAWTERLTEYLRGKGVTGVAFYHGGMEHEERMLIQQQFMNDQLQLVIC
TSAFGMGVNKSNTRYIIHFHYPTNIASYLQEIGRAGRDGEPSIAILLCSPLDHDLPISIIEDELPSQSQIQFLFSLLQER
MFQTKELPIEEVEEICYNAARFNEQYWRFIRYHLEQLGIIQQRKLILESLSDEIMNRLIAEVEIRLRNKYSELENMKSWI
QVKECRREYLLRQFGYRKEGEVKNCCDYCHITKTDYKKRQAQQSDFDYNWETELQKLFGLEKMGE
>Mature_465_residues
MCYQLPGLMQEGTVLVVSPLLSLMEDQVTQLKYVVKNRVIAFNSFRTLQEKREAMKRLASYKFIFVSPEMLQSELLIREL
KKVHISLFVVDEAHCISQWGYDFRPDYKKLDVVIKNIGSPTVLALTATATKDVLRDIAESLNLENVTQHVYSIDRPNIAM
EVQFVETIEEKKEALLDQVMYLQGPGIVYCSSRAWTERLTEYLRGKGVTGVAFYHGGMEHEERMLIQQQFMNDQLQLVIC
TSAFGMGVNKSNTRYIIHFHYPTNIASYLQEIGRAGRDGEPSIAILLCSPLDHDLPISIIEDELPSQSQIQFLFSLLQER
MFQTKELPIEEVEEICYNAARFNEQYWRFIRYHLEQLGIIQQRKLILESLSDEIMNRLIAEVEIRLRNKYSELENMKSWI
QVKECRREYLLRQFGYRKEGEVKNCCDYCHITKTDYKKRQAQQSDFDYNWETELQKLFGLEKMGE

Specific function: Probable DNA helicase. Required in synaptic and/or post- synaptic stages of recombination. Probably has overlapping function with recQ (AC O34748). It probably acts to help generate ss-DNA from ds-DNA breaks [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI51242947, Length=322, Percent_Identity=38.8198757763975, Blast_Score=212, Evalue=5e-55,
Organism=Homo sapiens, GI51242943, Length=312, Percent_Identity=39.4230769230769, Blast_Score=212, Evalue=6e-55,
Organism=Homo sapiens, GI148612816, Length=312, Percent_Identity=39.4230769230769, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI110735439, Length=301, Percent_Identity=37.8737541528239, Blast_Score=199, Evalue=5e-51,
Organism=Homo sapiens, GI169218196, Length=301, Percent_Identity=37.8737541528239, Blast_Score=199, Evalue=7e-51,
Organism=Homo sapiens, GI14591902, Length=300, Percent_Identity=34.3333333333333, Blast_Score=183, Evalue=3e-46,
Organism=Homo sapiens, GI14591904, Length=300, Percent_Identity=34.3333333333333, Blast_Score=183, Evalue=3e-46,
Organism=Homo sapiens, GI4557365, Length=307, Percent_Identity=34.2019543973941, Blast_Score=172, Evalue=7e-43,
Organism=Homo sapiens, GI284005309, Length=323, Percent_Identity=33.7461300309598, Blast_Score=166, Evalue=5e-41,
Organism=Escherichia coli, GI48994977, Length=301, Percent_Identity=42.1926910299003, Blast_Score=227, Evalue=1e-60,
Organism=Caenorhabditis elegans, GI32564293, Length=302, Percent_Identity=38.7417218543046, Blast_Score=199, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI71987997, Length=333, Percent_Identity=33.9339339339339, Blast_Score=192, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI71987993, Length=333, Percent_Identity=33.9339339339339, Blast_Score=191, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI25145561, Length=304, Percent_Identity=34.5394736842105, Blast_Score=183, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17552866, Length=332, Percent_Identity=32.2289156626506, Blast_Score=163, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI71995724, Length=217, Percent_Identity=26.7281105990783, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17507121, Length=217, Percent_Identity=26.7281105990783, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71987143, Length=256, Percent_Identity=24.21875, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6323844, Length=303, Percent_Identity=36.6336633663366, Blast_Score=189, Evalue=9e-49,
Organism=Saccharomyces cerevisiae, GI6324217, Length=321, Percent_Identity=23.6760124610592, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24664226, Length=303, Percent_Identity=35.973597359736, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24664230, Length=303, Percent_Identity=35.973597359736, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI62472181, Length=303, Percent_Identity=35.973597359736, Blast_Score=189, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24646066, Length=301, Percent_Identity=35.8803986710963, Blast_Score=189, Evalue=3e-48,
Organism=Drosophila melanogaster, GI21358123, Length=318, Percent_Identity=34.9056603773585, Blast_Score=168, Evalue=8e-42,
Organism=Drosophila melanogaster, GI24666101, Length=234, Percent_Identity=28.2051282051282, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR002464
- InterPro:   IPR004589
- InterPro:   IPR001650
- InterPro:   IPR014021 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 54468; Mature: 54468

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS00690 DEAH_ATP_HELICASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCYQLPGLMQEGTVLVVSPLLSLMEDQVTQLKYVVKNRVIAFNSFRTLQEKREAMKRLAS
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHC
YKFIFVSPEMLQSELLIRELKKVHISLFVVDEAHCISQWGYDFRPDYKKLDVVIKNIGSP
CEEEEECHHHHHHHHHHHHHHHHEEEEEEEECHHHHHHCCCCCCCCHHHHHHHHHHCCCC
TVLALTATATKDVLRDIAESLNLENVTQHVYSIDRPNIAMEVQFVETIEEKKEALLDQVM
EEEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHH
YLQGPGIVYCSSRAWTERLTEYLRGKGVTGVAFYHGGMEHEERMLIQQQFMNDQLQLVIC
HHCCCCEEEECCHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEE
TSAFGMGVNKSNTRYIIHFHYPTNIASYLQEIGRAGRDGEPSIAILLCSPLDHDLPISII
EHHHCCCCCCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHH
EDELPSQSQIQFLFSLLQERMFQTKELPIEEVEEICYNAARFNEQYWRFIRYHLEQLGII
HCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQRKLILESLSDEIMNRLIAEVEIRLRNKYSELENMKSWIQVKECRREYLLRQFGYRKEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
EVKNCCDYCHITKTDYKKRQAQQSDFDYNWETELQKLFGLEKMGE
CHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCHHHCCC
>Mature Secondary Structure
MCYQLPGLMQEGTVLVVSPLLSLMEDQVTQLKYVVKNRVIAFNSFRTLQEKREAMKRLAS
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHC
YKFIFVSPEMLQSELLIRELKKVHISLFVVDEAHCISQWGYDFRPDYKKLDVVIKNIGSP
CEEEEECHHHHHHHHHHHHHHHHEEEEEEEECHHHHHHCCCCCCCCHHHHHHHHHHCCCC
TVLALTATATKDVLRDIAESLNLENVTQHVYSIDRPNIAMEVQFVETIEEKKEALLDQVM
EEEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHH
YLQGPGIVYCSSRAWTERLTEYLRGKGVTGVAFYHGGMEHEERMLIQQQFMNDQLQLVIC
HHCCCCEEEECCHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEE
TSAFGMGVNKSNTRYIIHFHYPTNIASYLQEIGRAGRDGEPSIAILLCSPLDHDLPISII
EHHHCCCCCCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHH
EDELPSQSQIQFLFSLLQERMFQTKELPIEEVEEICYNAARFNEQYWRFIRYHLEQLGII
HCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQRKLILESLSDEIMNRLIAEVEIRLRNKYSELENMKSWIQVKECRREYLLRQFGYRKEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
EVKNCCDYCHITKTDYKKRQAQQSDFDYNWETELQKLFGLEKMGE
CHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377; 9642195 [H]