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The map label for this gene is mrdB [H]

Identifier: 222094771

GI number: 222094771

Start: 1095703

End: 1096902

Strand: Direct

Name: mrdB [H]

Synonym: BCQ_1109

Alternate gene names: 222094771

Gene position: 1095703-1096902 (Clockwise)

Preceding gene: 222094770

Following gene: 222094772

Centisome position: 21.01

GC content: 35.75

Gene sequence:

>1200_bases
GTGGCAACGGAACTAGACTTTCACTTGAAACAGACGAAGGATATGTGGATAGGGAAAGGGTTAAGTGAGGAAGTTGCTGA
AGATAAGGCTGTTGAACAAATGGGGAGTCCGATTAAACTGGGGCAGGAACTTAACAAACTTCATAAGCCAAAGGTTGATT
GGTTTTTAATTGGTTTATTAGTGGCTGCGATGGGGTTAGGGTTTTTGCCGGTTATAGCTTTTGGATATATGAATGATTTA
CTAATGGATAAAGTGATATTTGTTGTTCTTGGTATTGCAACAGCGTTAGGGATGATGCTGATTAATTATCGGAAGTTAGA
GAGATTAGGATGGTTGTTTTATACAATTGGTGTACTTATCTTGTTAATGCTATACTGCTTTCCGAATGCTGGGATGCTTG
GAGAACCGATAATAAAAGTTGGTCCTATTGCAATTGACCGTTTAATGGCAGTGCCGTTCTTTTTTCTAGCTTGGGCTTCT
TTTTTCAATAATAGTAGGATAAAAGTAATGCATCTTGTGGCTCTTTATTTATTTTCTTTGTATTTATTTTTAATTGGCGC
AGCTTTTTCAGTGATTTTTATTTATATCACGATGGTATTCGTTATGCTTTGGTGGAGTAAGTTAGGGAAGAAAAAGGCAT
TAATTATTACAATTGTACCAATCTGTTTATTGATTATAGGGGTCTATTTTTCCTGGCACACAGTAAAAGGAGTTTATTTG
GATAGATTTTTAGGGTATTTGAATCCAGAGCGTGATGCACAGGGCGCAGGATTTATGTATATACGTTTAAAGGAGGTAAT
GTCGTCAGCAGGTTGGTTTGGTACATACGGAGATGTAAAGTTCATCCCTAATCCAGATACTGATTTTGTATTTGCAAGTT
TGACTTATTATTATGGATATGTGCTTGCACTGGTCCTTGTCTTAATTCTTTCTCTTTTTGTAGCACGGTTAATCTTCATA
TCTTATACAATAAATGACCGATATGGTAAATTGCTTCTCATTGGAGGCATGACTCTTTTCGTAGTACAATTCCTTTATAA
CGTCGGTATGATTTTAGGTTTATTACCGATTACTGCTATATCATTACCTTTTATTAGTTATGGATTAACACCTACTTTAT
TTCATGCATTTTTAATGGGAATCGTGTTAAGTGTATATAGGCGTAAAGATGTGTCGTTTAGAAGGGAAGAGACAACTTGA

Upstream 100 bases:

>100_bases
AAAGGATTAGTACAGGAGTGAGAACAAATTGAACAAAAAAGGGGAGCGTTTTTTAAAAGAAGTTACGAACCATATTAAAT
CAAAAGAAGCAAAGGACTTA

Downstream 100 bases:

>100_bases
TGATTTGAAGTGAACCCGAATAGTGGTACATAAAAAAACACAAGAGTTCATTACCTAGAAGAAATAAAGTGAAAAGTGAT
TGGAATGAAAAAGGATGGTT

Product: cell division protein, ftsw/roda/spove family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MATELDFHLKQTKDMWIGKGLSEEVAEDKAVEQMGSPIKLGQELNKLHKPKVDWFLIGLLVAAMGLGFLPVIAFGYMNDL
LMDKVIFVVLGIATALGMMLINYRKLERLGWLFYTIGVLILLMLYCFPNAGMLGEPIIKVGPIAIDRLMAVPFFFLAWAS
FFNNSRIKVMHLVALYLFSLYLFLIGAAFSVIFIYITMVFVMLWWSKLGKKKALIITIVPICLLIIGVYFSWHTVKGVYL
DRFLGYLNPERDAQGAGFMYIRLKEVMSSAGWFGTYGDVKFIPNPDTDFVFASLTYYYGYVLALVLVLILSLFVARLIFI
SYTINDRYGKLLLIGGMTLFVVQFLYNVGMILGLLPITAISLPFISYGLTPTLFHAFLMGIVLSVYRRKDVSFRREETT

Sequences:

>Translated_399_residues
MATELDFHLKQTKDMWIGKGLSEEVAEDKAVEQMGSPIKLGQELNKLHKPKVDWFLIGLLVAAMGLGFLPVIAFGYMNDL
LMDKVIFVVLGIATALGMMLINYRKLERLGWLFYTIGVLILLMLYCFPNAGMLGEPIIKVGPIAIDRLMAVPFFFLAWAS
FFNNSRIKVMHLVALYLFSLYLFLIGAAFSVIFIYITMVFVMLWWSKLGKKKALIITIVPICLLIIGVYFSWHTVKGVYL
DRFLGYLNPERDAQGAGFMYIRLKEVMSSAGWFGTYGDVKFIPNPDTDFVFASLTYYYGYVLALVLVLILSLFVARLIFI
SYTINDRYGKLLLIGGMTLFVVQFLYNVGMILGLLPITAISLPFISYGLTPTLFHAFLMGIVLSVYRRKDVSFRREETT
>Mature_398_residues
ATELDFHLKQTKDMWIGKGLSEEVAEDKAVEQMGSPIKLGQELNKLHKPKVDWFLIGLLVAAMGLGFLPVIAFGYMNDLL
MDKVIFVVLGIATALGMMLINYRKLERLGWLFYTIGVLILLMLYCFPNAGMLGEPIIKVGPIAIDRLMAVPFFFLAWASF
FNNSRIKVMHLVALYLFSLYLFLIGAAFSVIFIYITMVFVMLWWSKLGKKKALIITIVPICLLIIGVYFSWHTVKGVYLD
RFLGYLNPERDAQGAGFMYIRLKEVMSSAGWFGTYGDVKFIPNPDTDFVFASLTYYYGYVLALVLVLILSLFVARLIFIS
YTINDRYGKLLLIGGMTLFVVQFLYNVGMILGLLPITAISLPFISYGLTPTLFHAFLMGIVLSVYRRKDVSFRREETT

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=193, Percent_Identity=29.5336787564767, Blast_Score=73, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 45273; Mature: 45142

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
ATELDFHLKQTKDMWIGKGLSEEVAEDKAVEQMGSPIKLGQELNKLHKPKVDWFLIGLL
CCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHH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HHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]